Clinical trials: Vasospasm, Cerebral
Subarachnoid Hemorrhage
Constitution of Cerebrospinal Fluid and Blood Database/Specimen in Acute Stage of Subarachnoid Hemorrhage (aSAH) Patients
Neuropeptide Y (NPY) may play a major role in the pathophysiology of aneurysmal subarachnoid hemorrhage (aSAH). To investigate the correlation of NPY in cerebrospinal fluid (CSF) and blood (serum) and the neurological outcome in…
- Trial name
- NCT01292278
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Vasospasm, Intracranial, Subarachnoid Hemorrhage
Lumenate Observational Vasospasm Interventional Trial (LOVIT)
The LOVIT study is a European prospective, multi-center, open-label, single-arm feasibility trial designed to determine the safety and angiographic effectiveness through 30 days post treatment with Lumenate Intraluminal Device in…
- Trial name
- LOVIT (NCT03511040)
- Testing
- Lumenate Intraluminal Device
- Where
- 5 sites in France, Germany and 2 more
- Volunteers
- 20 people
- Sponsor
- Neurvana Medical
Cerebral Vasospasm
Milrinone in Addition to Hyperdynamic Therapy in the Treatment of Vasospasm Following Aneurysmal Subarachnoid Hemorrhage
The purpose of this study is to evaluate the usefulness of adding Milrinone to the current standard treatment for cerebral vasospasm.
- Trial name
- NCT02712788
- Testing
- Milrinone
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Indiana University
Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia
Epigenome-wide DNA Methylation Profiling in Aneurysmal Subarachnoid Hemorrhage and Delayed Ischemic Neurologic Deficit
The goal of this observational study is to investigate DNA methylation changes in adults with bleeding from brain aneurysm, which is called aneurysmal subarachnoid hemorrhage (aSAH), and their association with delayed ischemic…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm After Subarachnoid Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT06881329
- Where
- Poland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Cerebral Ischemia, Subarachnoid Hemorrhage
Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage
The objective of this multi-centre, randomized controlled trial is to investigate the outcome after induced hypertension versus no induced hypertension in patients with delayed cerebral ischemia (DCI) after aneurysmal…
- Trial name
- HIMALAIA (NCT01613235)
- Testing
- Induced hypertension
- Where
- 2 sites in Netherlands
- Volunteers
- 26 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cerebral Vasospasm, Delayed Cerebral Ischemia
Bilateral Bispectral Index (BIS) Study
The purpose of this study is to assess real time changes in raw and processed EEG in relation to the clinical and radiological evidence of cerebral vasospasm.
- Conditions
- Cerebral Vasospasm, Delayed Cerebral Ischemia, Subarachnoid Hemorrhage
- Trial name
- BIS (NCT01187420)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cerebral Vasospasm, Subarachnoid Hemorrhage
Safety Study of Sildenafil in Treatment of Cerebral Aneurysm Vasospasm
Rupture of a cerebral aneurysm is a serious medical condition that may result in permanent disability or even death just related to the aneurysm rupture itself.
- Trial name
- NCT00871065
- Testing
- Sildenafil citrate
- Sponsor
- University of Nebraska
Subarachnoid Hemorrhage, Aneurysmal
SAHaRA: A Randomized Controlled Trial
The SAHaRA trial will clarify the role of treating anemia with Red Blood Cell (RBC) transfusion in a unique and vulnerable patient population, and determine whether that impacts on functional outcomes and mortality.
- Trial name
- NCT03309579
- Testing
- Liberal RBC Transfusion Strategy, Restrictive RBC Transfusion Strategy
- Where
- 23 sites in United States, Australia and 1 more
- Volunteers
- 742 people
- Sponsor
- Ottawa Hospital Research Institute
Subarachnoid Hemorrhage
Correlation of Various Laboratory Parameters With Outcome in Patients Suffering From Acute Non-traumatic Subarachnoid Hemorrhage - Prospective Case Series
In this prospective study, the investigators aim to investigate the effect of the following three factors on the development of vasospasm and patient outcome: (1.) the role of anemia; (2.) the role of plasma fibrinolytic…
- Trial name
- NCT05403970
- Where
- Hungary
- Volunteers
- 300 people
- Sponsor
- University of Debrecen