Clinical trials: Vein Collapse
IVC Collapsibility Index, Hemorrhagic Shock
The Cutoff Point for Caval Index and Its Correlation With Central Venous Pressure and Plasma Lactate Level for Assessing Patients in Hypovolemic Hemorrhagic States
The purpose of this study is to determine the cutoff point for IVC collapsibility index (by Bedside Ultrasonographic technique) for cases in hypovolemic hemorrhagic shock with CVP measures less than 8 cmH2o.
- Trial name
- NCT01741818
- Testing
- Measuring IVC collapsibility index by bedside ultrasonography
- Where
- 2 sites in Iran
- Volunteers
- 106 people
- Sponsor
- Isfahan University of Medical Sciences
Kidney Injury, Acute
Effects of Continuous Veno-venous Haemofiltration on Plasma Lactate in Critically Ill Patients
Continuous Veno-Venous Hemofiltration (CVVH) can eliminate metabolic products effectively and replace renal function partly. It is widely used in intensive care units (ICUs), especially for patients with acute kidney…
- Trial name
- NCT01824771
- Testing
- Plasma lactate were measured
- Where
- China
- Volunteers
- 15 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Septic Shock
The Effect of Lactate Clearance Oriented Haemodynamic Therapy on the Outcome of Patients With Septic Shock
The purpose of this study is to explore and assess possible outcome benefits of lactate clearance>30% vs ScvO2 ≥70% in 6 hours as the protocol goal that evaluated adequacy of during early resuscitation of septic shock through a…
- Trial name
- NCT02566460
- Testing
- Resuscitation
- Volunteers
- 360 people
- Sponsor
- Peking Union Medical College Hospital
Sepsis, Septic Shock
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Background: Central Venous catheter insertion technique and indwelling time are major risk factors for CVC colonisation. Colonisation occurs through microbial migration and biofilm formation along the catheter insertion tract.
- Conditions
- Sepsis, Septic Shock, Post-cardiac Surgery, Post-Cardiorespiratory Arrest Coma
- Trial name
- NCT03270774
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makerere University
Shock
PICU Admission Lactate and Central Venous Oxymetry Study
Observational multicentre cohort study. Children admitted to a Dutch PICU are studied for lactate levels and ScvO2. Children instrumented with arterial and central venous catheters are included within the first 12 hours after…
- Trial name
- PALVOS (NCT01696175)
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Radboud University Medical Center
Acute Myocardial Infarction Complicated With Cardiogenic Shock, Mild Therapeutic Hypothermia
Evaluation of MTH in PCI Under VA-ECMO for AMICS
This study is a randomized controlled trial conducted at Beijing Anzhen Hospital, Capital Medical University. The primary objective is to assess the efficacy of mild therapeutic hypothermia in reducing infarct size and improving…
- Conditions
- Acute Myocardial Infarction Complicated With Cardiogenic Shock, Mild Therapeutic Hypothermia, Venous-arterial Extracorporeal Membrane Oxygenation
- Trial name
- HOPE-CS (NCT07186972)
- Testing
- Mild therapeutic hypothermia
- Volunteers
- 44 people
- Sponsor
- Beijing Anzhen Hospital
Septic Shock, Sepsis
Venous Excess Ultrasound for Personalized Resuscitation in Septic Shock
The goal of this pilot clinical trial is to determine if conducting a larger study using venous excess ultrasound (VEXUS) to guide fluid management in patients with septic shock is feasible.
- Conditions
- Septic Shock, Sepsis, Shock, Critical Care, Intensive Care
- Trial name
- VESPER (NCT06696391)
- Testing
- Venous Excess Ultrasound (VEXUS)-Guided Management
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Western University, Canada
Sepsis, Disease Progression
Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency Department
To investigate the role of initial venous lactate in predicting the severity progression to overt septic shock and 30-day mortality in non-elderly patients without hemodynamic shock who suspected to have acute infections.
- Conditions
- Sepsis, Disease Progression, Septic Shock, Fatal Outcome
- Trial name
- NCT01947127
- Where
- Thailand
- Volunteers
- 458 people
- Sponsor
- Chulalongkorn University
Intracranial Pressure, Critical Care
JUgular Gating for Upright Level Adjustment and Targeted Enhancement of Cerebral Perfusion
Investigators aim to demonstrate that the evolution of intracranial pressure (ICP) is nonlinear and may be influenced by jugular vein collapse.
- Trial name
- JUGULATE (NCT07665606)
- Testing
- Ultrasound assessment
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bordeaux
Shock
GapCO2 and Respiratory Rate in Patients Under Volume Mechanical Ventilation
As an approximate of the difference between venous-to-arterial CO2 tension (∆PCO2), ∆PCO2 is proportional to CO2 production and inversely related to cardiac output (Fick equation).
- Trial name
- gapCO2 (NCT02867943)
- Testing
- Effects of respiratory rate on gapCO2
- Volunteers
- 28 people
- Sponsor
- 105 Hospital of Chinese People's Liberation Army
AKI - Acute Kidney Injury, Fluid Balance
Fluid Balance Guided by Modified Venous Excess Ultrasonography Versus Standard Care in Patients With Acute Kidney Injury Receiving Continuous Renal Replacement Therapy
The goal of this randomised controlled trial is to compare the cumulative fluid balance over the first 72 h following inclusion guided by mVExUS versus standard of care in critically ill patients with acute kidney injury…
- Conditions
- AKI - Acute Kidney Injury, Fluid Balance, Acute Circulatory Failure, Continuous Renal Replacement Therapy (CRRT)
- Trial name
- mVExUS-CRRT (NCT07346118)
- Testing
- mVExUS-guided fluid management
- Where
- 2 sites in Thailand
- Volunteers
- 126 people
- Sponsor
- Chulalongkorn University
Necrotizing Fascitis, Cellulitis
Validation of the Use of the Arteriovenous Tension Difference in CO2 Under Hyperbaric Conditions
The central venous-arterial carbon dioxide tension difference is used daily in intensive care to establish peripheral tissue hypoperfusion, mainly mediated by a low cardiac index.
- Conditions
- Necrotizing Fascitis, Cellulitis, Septic Shock
- Trial name
- SEPTICO2HBO (NCT07492030)
- Testing
- Echography
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Lille
Shock, Hypovolemia
Predicting Volume Response Study
The purpose of this study is to understand and document measurements in heart stroke volume (the volume or amount of blood pumped per heart beat) and cardiac output (the volume or amount of blood pumped by your heart per minute)…
- Trial name
- PVRS (NCT01656954)
- Testing
- Passive Leg Raise (PLR)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Pennsylvania
Shock
Effects of Increasing Mean Arterial Pressure on Renal Function in Patients With Shock and With Elevated Central Venous Pressure
The purpose of this study is to assess the effect of a higher mean arterial pressure on renal function for patients with shock and elevated central venous pressure.
- Trial name
- MAPAKI (NCT05655065)
- Testing
- increase of mean arterial pressure at 65-70 mmHg, increase of mean arterial pressure at 80-85 mmHg
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Angers
Cesarean Section Complications, Regional Anesthesia Morbidity
Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index and Shock Indices
Jugular vein collapsibility index and shock indices (Shock index, Modified Shock Index, Diastolic Shock Index) may be useful in estimating post spinal hypotension in cesarean section operations.
- Conditions
- Cesarean Section Complications, Regional Anesthesia Morbidity, Hemodynamic Instability, Shock
- Trial name
- NCT05953129
- Testing
- Right Jugular Vein Collapsibility Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Shock, Hypovolemia
Bedside Ultrasound Measurement of the Inferior Vena Cava Correlates to Central Venous Pressure
This study proposes to examine the correlation of central venous pressure to measures of the diameter of the inferior vena cava as determined by bedside ultrasonography.
- Conditions
- Shock, Hypovolemia, Hypervolemia
- Trial name
- NCT00596921
- Volunteers
- 100 people
- Sponsor
- Brooke Army Medical Center
Septic Shock, Vein Collapsibility
Fluid Responsiveness in Septic Shock Evaluated by Caval Ultrasound Doppler Examination
The study aims at clarification of venous collapsibility measures with real venous flow measurements during dynamic maneuver testing fluid responsiveness in septic shock patients.
- Conditions
- Septic Shock, Vein Collapsibility, Intravascular Doppler, Volume Responsiveness in Septic Shock
- Trial name
- FRIEND (NCT02676427)
- Testing
- passive leg raising
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Charles University, Czech Republic
Shock
Central Venous Oxygen Saturation and Carbone Dioxide (CO2)-Derived Indices in the Critically:
The optimal management of shock states requires a precise evaluation of several parameters, clinical, biological, hemodynamic, and echocardiographic.
- Trial name
- NCT05220696
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Montpellier
Cardiogenic Shock
ECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic Shock
In the ECMOsorb study the impact of a veno-arterial -ECMO in combination with an extracorporeal cytokine hemadsorption system in critically ill patients with cardiogenic shock is to be examined
- Trial name
- ECMOsorb (NCT05027529)
- Testing
- CytoSorb, VA-ECMO only
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Christian Schulze
Central Venous Pressure and Inferior Vena Cava Distensibility Index in Assessing Fluid Responsiveness in Septic Shocked Patients
Central Venous Pressure Versus Inferior Vena Cava Distensibility Index in Assessing Fluid Responsiveness in Septic Shocked Patients
This study aims to compare ultrasound-guided inferior vena cava distensibility index(IVC_DI) assessment with central venous pressure (CVP) monitoring for the detection of hypovolemia in septic shocked patients in the emergency…
- Trial name
- NCT07279064
- Testing
- Ultrasound guided inferior vena cava distensibility index
- Volunteers
- 70 people
- Sponsor
- Assiut University