Clinical trials: Venous
Venous Thromboembolism
Comparison of Bleeding Risk Between Rivaroxaban and Apixaban: The Pilot Study
This vanguard pilot study compares rivaroxaban and apixaban, two of the new oral blood thinners for the treatment of blood clots. Half of the patients will receive apixaban and half will receive rivaroxaban.
- Trial name
- COBRRA Pilot (NCT02559856)
- Testing
- Apixaban, Rivaroxaban
- Where
- 4 sites in Canada
- Volunteers
- 71 people
- Sponsor
- Ottawa Hospital Research Institute
Cerebral Vein Thrombosis
Venous Sinus Thrombosis : Clinical Picture and Outcome
Cerebral venous sinus thrombosis (cvst) is an underdiagnosed neurological condition with variable clinical presentations and variable risk factors CVST is often an underdiagnosed cause of acute or slowly progressive neurological…
- Trial name
- NCT05211102
- Volunteers
- 50 people
- Sponsor
- Assiut University
Malaria Falciparum, Malaria Infection
Age De-escalation Safety Trial of PfSPZ-LARC2 Vaccine in Burkina Faso
This is a first-in-humans randomized, double-blind, placebo-controlled, age de-escalation Phase 1 trial of Plasmodium falciparum (Pf) late liver stage-arresting replication-competent (LARC) sporozoite (SPZ) malaria vaccine…
- Trial name
- NCT06652737
- Testing
- PfSPZ-LARC2 Vaccine
- Where
- Burkina Faso
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sanaria Inc.
Deep Venous Thrombosis
Rivaroxaban for Scheduled Work-up of DVT - The Ri-Schedule Study
This prospective outcome study is designed to assess the safety of rivaroxaban in the pre-diagnosis phase of DVT.
- Trial name
- Ri-Schedule (NCT02486445)
- Testing
- Rivaroxaban
- Where
- Norway
- Volunteers
- 625 people
- Sponsor
- Ostfold Hospital Trust
Stenosis in Saphenous Vein Graft, Drug Eluting Stent
Comparison of Safety and Efficacy of Two Different Drug Eluting Stents Implanted Into Saphenous Vein Grafts
Drug eluting stents significantly reduced the rate of in-stent restenosis in coronary arteries. There are several kinds of DES i.e. eluting the drug either from stable or biodegradable polymer.
- Trial name
- NCT00766129
- Testing
- Taxus stent implantation, Luc-Chopin stent
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Varicose Veins, Venous Insufficiency
The Party Balloon Assisted Valsalva in Diagnosis of Superficial Venous Valvular Reflux of Lower Limb
This study was designed to compare the party balloon assisted Valsalva with the conventional Valsava for exhibiting the reverse venous flow in superficial venous valvular incompetence duplex examination.
- Trial name
- NCT02051439
- Testing
- Valsava
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy
Penile Implant Intraoperative Measurements Planning Chart
This is a chart of penile size measurements where penile length and width are recorded intra-operatively prior to penile prosthesis implantation to guide the surgeon to the correct and adequate post-operative penile size
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction With Diabetes Mellitus, Erectile Dysfunction Due to Arterial Disease
- Trial name
- PIIMP (NCT05531877)
- Testing
- Penile Prosthesis Implantation
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
IVC Collapsibility Index
Accuracy of IVCCI as a Measure of CVP
The primary aim of the current study is to examine the accuracy of IVCCI for measurement of CVP and to derive equation or formula to predict CVP from IVCCI.
- Trial name
- NCT06166875
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Nermeen Shawky Ahmed Mohamed
Pulmonary Embolism
Accuracy of Multi-organ Ultrasound for the Diagnosis of Pulmonary Embolism
Patients with suspected Pulmonary Embolism (PE) and a high clinical probability or a high D-dimer level should undergo a second level diagnostic test such as Multidetector Computed Tomography Angiography (MCTPA).
- Trial name
- SPES (NCT01635257)
- Testing
- Ultrasound scan
- Where
- 3 sites in Italy
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Chronic Venous Insufficiency
A Feasibility Study of the ReLeaf Catheter System
This study is designed to evaluate the safety and technical feasibility of the ReLeaf Catheter System in the creation of one or more tissue leaflets in the femoral and/or popliteal vein in subjects with chronic venous…
- Trial name
- ReLeaf (NCT02462096)
- Testing
- ReLeaf
- Where
- New Zealand
- Volunteers
- 2 people
- Sponsor
- Intervene, Inc.
Paroxysmal Atrial Fibrillation
SINGLE SHOT CHAMPION
Pulmonary vein isolation (PVI) is an effective treatment for atrial fibrillation (AF). Currently, Medtronic Arctic Front Cryoballoon is the most frequently used single shot technology and hence is the benchmark for upcoming…
- Trial name
- NCT05534581
- Testing
- PVI using the Arctic Front Cryoballoon (Medtronic), PVI using FARAPULSE Pulsed Field Ablation (Boston Scientific)
- Where
- 2 sites in Switzerland
- Volunteers
- 210 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Internal Jugular Vein Cannulation
Sono-ease Device for Internal Jaguar Vein Cannulation
A novel device attached to ultrasound probe designed to increase success rate and safety of internal jugular vein cannulation.
- Trial name
- Sono-ease (NCT02973841)
- Testing
- Sono-ease device
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Acidosis, Lactic
D4T or Abacavir Plus Vitamin Enhancement in HIV-Infected Patients (DAVE)
The purpose of this study is to determine the best way to treat people on d4T (stavudine) with high levels of lactic acid. Switching from d4T to abacavir will be assessed. Adding riboflavin and thiamine will also be assessed.
- Trial name
- NCT00143702
- Testing
- d4T, Abacavir, Riboflavin and Thiamine (Supplementation)
- Where
- 2 sites in Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Venous Thromboembolism
Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Hip Fracture Surgery
The objective of this study is to evaluate the safety and efficacy of DU-176b compared with enoxaparin sodium for the prevention of venous thromboembolism in patients after elective hip fracture surgery.
- Trial name
- NCT01181141
- Testing
- DU-176b (edoxaban), Enoxaparin sodium 20mg
- Where
- Japan
- Volunteers
- 92 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Varicose Veins
Comparison of Radiofrequency, Vein Stripping and CHIVA for Venous Insufficency
Randomized controlled clinical trial aimed to compare the effectiveness and safety of radiofrequency, saphenous vein stripping and conservative hemodynamic treatment of venous insufficiency (CHIVA) in the treatment of saphenous…
- Trial name
- NCT02454452
- Testing
- Radiofrequency, Saphenous vein stripping, CHIVA
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Corporacion Parc Tauli
Pressure Ulcer, Venous Ulcer
PuraPly™ Antimicrobial Wound Matrix and Wound Management
The PuraPly Antimicrobial Wound Matrix (PuraPly AM) case series is a prospective, observational study for patients who have received PuraPly AM which consists of a collagen sheet coated with polyhexamethylenbiguanide…
- Conditions
- Pressure Ulcer, Venous Ulcer, Diabetic Ulcer, Surgical Wound
- Trial name
- PuraPlyAM (NCT03070938)
- Testing
- PuraPly™ Antimicrobial Wound Matrix
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Organogenesis
Stenosis, Restenosis
Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft in AV Graft Patients (AVeVA)
The objective of this study is to assess the safety and effectiveness of the COVERA™ Vascular Covered Stent for the treatment of stenotic lesions in the upper extremity venous outflow of the Arteriovenous (AV) access circuit.
- Trial name
- AVeVA (NCT02790606)
- Testing
- Covera(TM) Vascular Covered Stent
- Where
- 16 sites in United States
- Volunteers
- 110 people
- Sponsor
- C. R. Bard
Abdominal Aortic Aneurysm, Deep Vein Thrombosis
Evaluation of a New Imagingtechnologie for Thrombosis
Arterial and venous thrombi play an important role in various vascular diseases such as myocardial infarction, stroke, transient ischemic attacks (TIA) and pulmonary embolism.
- Trial name
- PET-GP1_1 (NCT02469376)
- Testing
- [18F]-GP1
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- University of Zurich
Sepsis, Sepsis Bacterial
Analytical Validation of the abioSCOPE Device With the IVD CAPSULE PSP Test: Comparison of PSP Values Measured With Venous Whole Blood and Those Measured With Arterial Whole Blood.
Abionic has developed a targeted, rapid test for pancreatic stone protein (PSP) in human K2-EDTA venous whole blood using the abioSCOPE instrument.
- Trial name
- NCT05627076
- Testing
- Blood Sampling
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Abionic SA
Idiopathic Intracranial Hypertension (IIH)
Stenting Of Symptomatic Cerebral siNus stenosIs With the laserCut Self-expanding SILANCE Stent
The objective of this clinical investigation is to evaluate and demonstrate the clinical benefit, performance, and safety of the SILANCE Stent, which is specifically designed for the treatment of patients with symptomatic sinus…
- Trial name
- SONIC (NCT07561268)
- Testing
- SILANCE Stent Implantation
- Volunteers
- 99 people
- Sponsor
- Acandis GmbH
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