Clinical trials: Venous
Venous Thromboembolism
Dose-Ranging Study of BAY 59-7939 on the Prevention of VTE in Patients Undergoing Elective Total Hip Replacement
Patients undergoing surgery, especially hip and knee surgery, are at high risk for VTE. The administration of drugs for thromboprophylaxis, such as heparins, significantly lowers that risk, but heparins have to be applied by…
- Trial name
- ODIXa-HIP2 (NCT00398905)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Enoxaparin
- Where
- 61 sites in Austria, Belgium and 11 more
- Volunteers
- 726 people
- Sponsor
- Bayer
Heart Failure, Heart Failure - NYHA II - IV
Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
This is a pivotal, global, prospective, cross-sectional, multicentric clinical investigation designed to explore a non-invasive, reliable alternative to invasive, catheter-based hemodynamic assessments, which are associated with…
- Trial name
- NCT07222813
- Testing
- FibroScan, Right-sided Heart Catheterization, Transthoracic echocardiography
- Where
- 7 sites in United States, France and 2 more
- Volunteers
- 149 people
- Sponsor
- Echosens
Varicose Ulcer
A Clinical Study to Assess a Compression Device in Patients With Venous Leg Ulcers
The purpose of this study is to evaluate the product performance of a new adjustable compression system for the treatment of venous leg ulcers.
- Trial name
- NCT02561013
- Testing
- 3M™ Coban™ Custom Fit Compression System, Profore
- Where
- 5 sites in United States, Canada
- Sponsor
- 3M
Chronic Venous Hypertension With Ulcer and Inflammation, Venous Ulcer Pain
Electromagnetic Field Therapy to Improve Healing of Chronically Venous Ulcer
Chronically venous ulcer in lower extremities is a permanent and disabling disease. Venous insufficience is the main cause of chronic ulcer. There is a high prevalence and frequency of the disease, primarily among elderly people.
- Trial name
- NCT01561170
- Testing
- Active Pulsed Electro-Magnetic Field (PEMF)
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Deep Venous Thrombosis of Deep Femoral Vein
Venous Thrombosis Prevention and Sleep Quality: A Comparison of the Kendall and the Recovery Health MAC Systems
Venous thromboembolism is prevalent, associated with a high degree of morbidity and mortality, and largely preventable. External mechanical compression is a standard of care for prevention, but compliance with traditional…
- Trial name
- NCT06042686
- Testing
- RF Health MAC Device
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
SARS Virus
Prevalence and Risk Factors for Venous Thromboembolic Events in Critically Ill Patients With COVID-19
The purpose of the study is to assess the frequency of the occurrence of a venous thrombosis in patients with the new Coronavirus disease, who are admitted to the Intensive Care Unit for impending respiratory failure requiring…
- Trial name
- NCT04567927
- Testing
- Ultrasonography
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Chiesa Alessandro Felice
Covid-19
Bicentric Study on the Use of ECMO-VV or VA for Severe ARDS Associated With Covid-19
Describes the cohort of patients receiving ECMO-VV or ECMO-VA in the management of severe ARDS refractory to SARS-CoV-2 in the Strasbourg and Louvain centres
- Trial name
- ECMO-SL-CoV-2 (NCT04446286)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Venous Leg Ulcer
Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers
This study randomly assigns patients with venous leg ulcers to receive standard therapy (compression) alone or compression plus Dermagraft(R).
- Trial name
- DEVO (NCT00909870)
- Testing
- Dermagraft(R), Profore
- Where
- 70 sites in United States, Austria and 6 more
- Volunteers
- 537 people
- Sponsor
- Organogenesis
Pediatric Obesity, Sleep Apnea, Obstructive
Exercise and Venous Compression on Upper Airway Resistance in Obese Teenagers With OSA
The purpose of this study is to assess the effects of physical exercise, associated or not with venous compression of the leg, on obstructive sleep apnea (OSA) severity and upper airway resistance in obese teenagers.
- Trial name
- OBESOMAC (NCT02588469)
- Testing
- Interventional group, Control group
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Atrial Fibrillation, Cardioembolic Events
Prevention of Silent Cerebral Thromboembolism by Oral Anticoagulation With Dabigatran After Pulmonary Vein Isolation for Atrial Fibrillation
Oral anticoagulation treatment (OAC) following clinically successful catheter abla-tion of atrial fibrillation (AF) is controversial.
- Conditions
- Atrial Fibrillation, Cardioembolic Events, Oral Anticoagulation
- Trial name
- ODIn-AF (NCT02067182)
- Testing
- Dabigatran
- Where
- 19 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Georg Nickenig
Pneumothorax Iatrogenic Postprocedural, Malposition, Central Venous Catheter
Comparison of Bedside Ultrasound With Chest X-ray for Confirmation of Central Venous Catheter Position
Background: Insertion of a central venous catheter (CVC) could lead to a variety of complications. To detect those complications, Chest X-ray (CXR) is still the reference standard.
- Trial name
- COMBUX (NCT02959203)
- Where
- Netherlands
- Volunteers
- 750 people
- Sponsor
- Amsterdam UMC, location VUmc
Vascular Access Complication, Central Line Complication
Novel Strategy to Encourage Early Removal of Central Venous Catheters
The goal of this study is to determine if early placement of a midline catheter in patients with a central venous catheter (CVC) will decrease the number of days the CVC is in place.
- Conditions
- Vascular Access Complication, Central Line Complication, Central Line-Associated Infection, Superficial Vein Thrombosis
- Trial name
- NCT04136561
- Testing
- Midline catheter
- Where
- United States
- Sponsor
- Corewell Health East
Atrial Fibrillation
Efficacy of Anterior Wall PVI With QDOT Catheter - Intraprocedural Comparison Between vHPSD and HPSD Ablation.
This study is a prospective, randomized controlled study to evaluate intraprocedural efficacy of anterior aspects of pulmonary veins insolation between very High Power Short Duration (vHPSD) and High Power Short Duration (HPSD)…
- Trial name
- A-Q-RATE-POWER (NCT05780996)
- Testing
- QMODE +, QMODE
- Where
- 2 sites in Poland
- Volunteers
- 70 people
- Sponsor
- Medical University of Warsaw
Hepatocellular Carcinoma With Portal Vein Tumor Thrombus
Resection vs. Best Supportive Care for Hepatocellular Carcinoma (HCC) With Portal Venous Thrombus
The purpose of this study is to evaluate the long-term efficacy and safety of surgical resection compared with best supportive care in patients with resectable hepatocellular carcinoma (HCC) with portal venous thrombus (PVTT) in…
- Trial name
- NCT01600196
- Testing
- Liver resection plus Thrombectomy
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Sun Yat-sen University
Venous Thrombosis or Pulmonary Embolism
What Treatment for Patients With Phlebitis or Pulmonary Embolism ?
The objective of the "anticoagchoice" study is to analyze the preferences of people suffering from phlebitis, in terms of anticoagulant, to improve adherence to these treatments, to adapt the medical prescriptions.
- Trial name
- AntiCoagChoice (NCT03889457)
- Testing
- anticoagulation choice
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Rennes University Hospital
End-stage Renal Disease (ESRD)
Creating a Buttonhole Tunnel Track by Repeated Needling of the AV Fistula on the Same Day in Patients on Hemodialysis.
BACKGROUND: The patients diagnosed with end stage renal disease require dialysis and for that they need to have a vascular access for hemodialysis (HD) placed.
- Trial name
- NCT03989141
- Testing
- Repeated cannulation Buttonhole., Single cannulation Buttonhole.
- Where
- 2 sites in Denmark
- Volunteers
- 43 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Persistent Atrial Fibrillation, Catheter Ablation
Left Atrial Function Analysis for Patients With Persistent Atrial Fibrillation Undergoing Pulmonary Vein Isolation
This prospective observational study is designed to describe the factors determining the success of pulmonary vein isolation (PVI) for patients with persistent atrial fibrillation (AF).
- Trial name
- LAMPP (NCT03242694)
- Testing
- LA pressure, voltage map, strain, scar-map, blood sampling, pulmonary vein isolation
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Semmelweis University Heart and Vascular Center
COVID-19, Venous Thromboembolism
Prevalence and Severity of Venous Thromboembolism in a General Population During the COVID-19 Pandemic
The purpose of this study is to investigate the prevalence of venous thromboembolism in a regional health care system (Region Östergötland, Sweden) before and during the SARS-COV-2 pandemic.
- Conditions
- COVID-19, Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- NCT04400877
- Testing
- Diagnostic examination for venous thromboembolism
- Where
- Sweden
- Volunteers
- 7,795 people
- Sponsor
- University Hospital, Linkoeping
Diabete Mellitus, Retina Vein Occlusion
Serum Cholinesterases, Paraoxonase, and Cardiovascular Risk After Intravitreal Bevacizumab
Bevacizumab, an anti-VEGF (vascular endothelial growth factor) agent used in the treatment of diabetic retinopathy and macular edema associated with retinal vein occlusion, is commonly administered in ophthalmology clinics…
- Conditions
- Diabete Mellitus, Retina Vein Occlusion, Age Macular Degeneration
- Trial name
- NCT07550777
- Testing
- blood test
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Achilles Tendon Rupture, Deep Vein Thrombosis
Non-operative Treatment of Acute Achilles Tendon Rupture: Early Controlled Mobilization Compared With Immobilization
Study objectives To investigate if early controlled mobilization of the ankle in week 3 to 8 affects the functional outcome and patient reported outcome after treatment of acute Achilles tendon rupture.
- Trial name
- NCT02015364
- Testing
- Controlled early mobilization
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Hvidovre University Hospital
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