Clinical trials: Venous
Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Time Efficiency Comparison of Two IntraVitreal Injection Techniques
Prospective, single-center, randomized, clinical trial (RCT) comparing the time efficiency and safety of a single-use intravitreal injection (IVI) guide versus a traditional technique using a dual blade speculum among patients…
- Conditions
- Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion With Macular Edema, Uveitic Macular Edema
- Trial name
- TIVI (NCT04455399)
- Testing
- Intravitreal injection guide (Malosa), Dual Blade Eyelid Speculum
- Where
- Philippines
- Volunteers
- 200 people
- Sponsor
- Peregrine Eye and Laser Institute
Decompression Sickness, Endothelial Dysfunction
Exercise and Repetitive Diving
SCUBA diving frequently involves repetitive exposures over multiple days. The goal of this study was to see how exercise impacts microparticles (MPs), endothelial function, and venous gas emboli (VGE) over a series of dives.
- Conditions
- Decompression Sickness, Endothelial Dysfunction, Neutrophil Activation, Venous Gas Emboli
- Trial name
- NCT02118207
- Testing
- Aerobic running exercise
- Where
- 2 sites in United States, Croatia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Split
Hepatocellular Carcinoma, Hepatic Portal Vein Tumor Invasion
Combination Treatment for Advanced Liver Cancer
The purpose of this study is to determine whether TACE combined endovascular stent implantation confers a survival benefit over TACE alone.
- Trial name
- NCT02149771
- Testing
- chemoembolization, endovascular stents implantation, iodine-125 seed strand implantation
- Where
- China
- Sponsor
- Shanghai Zhongshan Hospital
Severe Sepsis, Septic Shock
Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring
The purpose of this study was to compare ACCM/PALS guidelines performed with and without central venous oxygen saturation monitoring on the morbidity and mortality rate of children with severe sepsis and septic shock.
- Trial name
- NCT00407823
- Testing
- Central venous oxygen saturation continuous monitoring
- Where
- 2 sites in Brazil
- Volunteers
- 268 people
- Sponsor
- University of Sao Paulo
Atrial Fibrillation
Same-Day Discharge Versus Overnight Stay Following Pulmonary Vein Isolation for Atrial Fibrillation
Prospective, randomized, controlled, multicentre study to compare the safety and efficacy of a Same Day Discharge (SDD) protocol in combination with a Perclose ProStyle (PPS) /ProGlide (PPG) suture mediated vascular closure…
- Trial name
- SHAzAM-AF (NCT06598280)
- Testing
- Atrial Fibrillation with femoral closure using closing system, Atrial Fibrillation with femoral closure using figure-of-eight stitch
- Where
- Germany
- Volunteers
- 270 people
- Sponsor
- University of Luebeck
Venous Thromboembolism, Blood Clot
Statins for Venous Event Reduction in Patients With Venous Thromboembolism
The standard or usual treatment for patients diagnosed with deep vein thrombosis or pulmonary embolism is treatment with blood thinners (called anticoagulants).
- Conditions
- Venous Thromboembolism, Blood Clot, Post Thrombotic Syndrome
- Trial name
- SAVER (NCT04319627)
- Testing
- Rosuvastatin Calcium
- Where
- 31 sites in Canada, France and 4 more
- Volunteers
- 2,700 people
- Sponsor
- Ottawa Hospital Research Institute
Venous Thromboembolism, covid19
Hemostasis and Inflammation in COVID-19 Patients With Venous and Arterial Thrombotic Complications
The study is aimed at assessing the role of the activity of high-risk markers of thrombotic events (MCP-1, MIP1α, IP-10, phosphatedylserine, calreticulin) on the development of thrombotic complications in patients with COVID -19.
- Conditions
- Venous Thromboembolism, covid19, Thrombosis
- Trial name
- NCT05143567
- Testing
- standard of care anticoagulation in absence of thrombotic complications, standard of care anticoagulation in presence of thrombotic complications, standard of care anticoagulation in combination with elastic compression
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Ryazan State Medical University
Acute Coronary Syndromes, Heart Failure
Prospective Cohort of Acute Cardiology Referrals in an Ambulatory Day-Hospital Setting
Suspected acute or subacute cardiovascular diseases-including chest pain, dyspnea, and palpitations-are among the most common reasons for unscheduled emergency department visits and pre-hospital referrals.
- Conditions
- Acute Coronary Syndromes, Heart Failure, Pulmonary Embolism, Deep Vein Thrombosis, HTN-Hypertension
- Trial name
- CESAR (NCT07675434)
- Volunteers
- 25,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Comparison of the Right and Left Internal Jugular Vein Using Ultrasound
Comparison of the Right and Left Internal Jugular Vein Using Ultrasound
The purpose of this study is to determine whether there is a difference between the diameter, and the cross-sectional area of the right internal in left internal jugular vein in preoperative, mechanically ventilated patients.
- Trial name
- NCT01599299
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Vision
Does the VTS1000 Infra Red Vein Imager Allow Better Identification of Veins Than Normal Eyesight?
VueTek has developed a head mounted device that will improve the viewing of superficial, subcutaneous vasculature, differentiating it with higher contrast from surrounding tissue.
- Trial name
- VFvalidation (NCT01138228)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Non-small Cell Lung Cancer
Endostar Durative Transfusion Combining With Gemcitabine-Cisplatin to Treat Non-Small Cell Lung Cancer (NSCLC)
The purpose of this study is to determine whether Endostar pumping into vein with Gemcitabine-Cisplatin are more effective than Endostar with Gemcitabine-Cisplatin regularly in the treatment of Non-Small Cell Lung Cancer (NSCLC).
- Trial name
- NCT01669707
- Testing
- Endostar -Continued Pumping into+GP, Endostar -injecting into +GP
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Chest Hospital
Lower Limb Venous Thrombosis
Grade Analysis of Veins by MRI and CT in Post-Thrombotic Syndrome
The aim is to improve the diagnosis of chronic lower limb venous thrombosis before a lower limb venous recanalization procedure.
- Trial name
- MR/CT PPS (NCT06451484)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Coronary Artery Disease, Coronary Artery Stenosis
Study of the No-touch Saphenous Vein Graft
Authors hypothesize that "no-touch" saphenous vein as I graft is superior over conventional "no-touch" saphenous vein as free graft in the incidence of graft patency.
- Conditions
- Coronary Artery Disease, Coronary Artery Stenosis, Graft Failure, Cardiac Ischemia
- Trial name
- NCT05757947
- Testing
- Сoronary bypass surgery according to the I-graft method, Сoronary bypass surgery by the method of free conduit
- Where
- Russia
- Volunteers
- 106 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Lung Neoplasms, Venous Thromboembolism
Venous Thromboembolism in Advanced Lung Cancer
This is a prospective observatory clinical study, aiming to establish and validate venous thromboembolism risk model in Chinese advanced non-small cell lung cancer.
- Trial name
- RIVAL (NCT03581708)
- Testing
- lung cancer
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- Guangdong Provincial People's Hospital
Atrial Fibrillation, CryoAblation
Wide Area Circumferential Ablation With Contact Force Versus Cryoballoon Ablation
The purpose of this randomized clinical trial is to compare the efficacy and safety of wide area circumferential ablation using contact force catheter with cryoballoon ablation for the treatment of paroxysmal atrial fibrillation.
- Conditions
- Atrial Fibrillation, CryoAblation, Pulmonary Vein Isolation
- Trial name
- WACACF vs Cryo (NCT03564925)
- Testing
- Wide area circumferential ablation, Cryoballoon ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Cardiovascular Diseases, Metabolic Disease
Vascular Lab Resource (VLR) Biorepository
This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases.
- Conditions
- Cardiovascular Diseases, Metabolic Disease, Peripheral Artery Disease, Carotid Disease
- Trial name
- NCT05628948
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- The Cleveland Clinic
Peripheral Venous Cannulation
Ultrasound Guided Peripheral Intravenous Catheterization in the Pediatric Intensive Care Unit.
This is a randomized controlled prospective study. The purpose of this study is to compare a recently described technique of ultrasound (US) guided, dynamic needle tip positioning (DNTP), to the traditional technique of vein…
- Trial name
- NCT04268225
- Testing
- US guided dynamic needle tip positioning peripheral intravenous cannulation, Traditional peripheral intravenous cannulation
- Volunteers
- 90 people
- Sponsor
- Rabin Medical Center
Atrial Fibrillation
Observational Study of Sinus Rhythm Mapping in Pulmonary Vein Isolation Naive Patients With Atrial Fibrillation
Atrial fibrillation (AF) initially starts in a paroxysmal form, which is mainly based on the presence of triggers. Progression of AF is accompanied by structural and electrical remodelling which can typically be described as a…
- Trial name
- SUSTAINER (NCT06098664)
- Testing
- AI-enabled ECG score for Atrial Fibrillation (DNN score), Atrial voltage map in sinus rhythm
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Ziekenhuis Oost-Limburg
Venous Malformation, Low Flow, Anticoagulants
A Study of Direct Oral Anticoagulants in Patients with Painful Venous Malformations with Localized Intravascular Coagulation
There are two parts of the study. In Part 1, the invesitgaotrs want to investigate whether treatment with apixaban improves pain and quality of life in patients with painful venous malformations The participants are randomized to…
- Trial name
- AVA (NCT06729034)
- Testing
- Apixaban (Eliquis)
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Varicose Veins, Endovenous Laser Ablation
Concomitant or Sequential Phlebectomy After Endovenous Laser Therapy for Varicose Veins
Varicose veins of the leg often have superficial tributaries, which are often symptomatic and a major reason for coming to the doctor.
- Conditions
- Varicose Veins, Endovenous Laser Ablation, Phlebectomies
- Trial name
- EVLTAP (NCT02017106)
- Testing
- Endovenous Laser ablation and concomitant phlebectomies, Endovenous Laser ablation and sequential phlebectomies
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
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