Clinical trials: Venous Congestion
Sepsis, Acute Kidney Injury
VExUS Combined With CVP to Predict Clinical Outcomes in Sepsis Participants
Introduction: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host immune response to infection, and it is a common critical condition in the ICU.
- Trial name
- NCT06524622
- Testing
- Point-of-care ultrasound (POCUS)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Second People's Hospital of Yibin
Varicocele, Pelvic Congestion Syndrome
Evaluation of PerformanCe of the Peripheral EOS in the Treatment of Varicocele or Pelvic Congestion SynDromE
To collect confirmatory data in support of the safety and performance of the ArtVentive Medical Group Endoluminal Occlusion System.
- Trial name
- OCCLUDE-I (NCT02033863)
- Where
- 3 sites in Belgium, Poland and 1 more
- Volunteers
- 40 people
- Sponsor
- ArtVentive Medical Group, Inc.
Mechanical Ventilation, Acute Respiratory Distress Syndrome (ARDS)
Relationship Between the Level of Positive End-expiratory Pressure and Venous Congestion During Acute Respiratory Distress Syndrome.
The main objective is to assess the effect of increased PEEP on echo-Doppler venous congestion in ARDS patients at two PEEP levels, by grading congestion in each venous flow (suprahepatic, renal, portal) as "absent," "moderate,"…
- Trial name
- SURVEX (NCT07452952)
- Testing
- Non-interventionnal study
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Angers
Pelvic Congestion Syndrome
Quality of Life Questionnaire and Disease Severity Scale
There are currently no specific validated patient-centric tools for the clinical evaluation of patients with chronic pelvic venous disorders (CPVD).
- Trial name
- NCT05889000
- Testing
- questionnaire responses
- Where
- Russia
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Kazan State Medical University
Intraoperative, Venous Congestion
Venous Congestion And Delirium After Cardiac Surgery
Postoperative delirium (POD) is an acute brain dysfunction characterized by inattention, impaired consciousness, and cognitive and orientation disturbances, and is a common complication after cardiac surgery.
- Conditions
- Intraoperative, Venous Congestion, Postoperative Delirium (POD), Cardiac Surgery
- Trial name
- NCT07285187
- Testing
- collection of demographic characteristics and comorbidities, surgery-related parameters, POD assessments
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhuan Zhang
Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
VExUS in Ards Patients and Association with AKI
A single-center prospective observational study will be conducted with the aim of determining the prevalence of venous congestion during ARDS using venous Doppler and the VExUS score.
- Trial name
- VEXAKI (NCT06805409)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Kidney Injury After Open Heart Surgery, Venous Congestion After Open Heart Surgery
Evaluation of the Association Between the VEXUS Score and Hemodynamic Status and the Occurrence of Acute Kidney Injury After Open-Heart Surgery
Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass and is associated with prolonged intensive care unit stay, increased morbidity, and mortality.
- Trial name
- NCT07805564
- Where
- Vietnam
- Volunteers
- 135 people
- Sponsor
- Hanoi Medical University
Acute Heart Failure
VExUS in Patients With Acute Heart Failure
The importance of assessing venous congestion in heart failure patients is widely acknowledged, but its study is hampered by the lack of a practical evaluation tool.
- Trial name
- NCT06397404
- Testing
- Venous excess ultrasound score (VExUS) protocol
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Renal Failure, Acute Renal Failure
External Validation of the VExUS Score for the Prediction of Acute Renal Failure in Cardiac Surgery
Acute renal failure is a frequent complication associated with significant morbidity and mortality in postoperative cardiac surgery.
- Conditions
- Renal Failure, Acute Renal Failure, Renal Insufficiency, Acute Renal Insufficiency
- Trial name
- ValiVexus (NCT05640518)
- Where
- France
- Volunteers
- 119 people
- Sponsor
- University Hospital, Grenoble
Venous Congestion, Organ Dysfunction Syndrome
Venous Congestion and Organ Dysfunction.
Venous congestion, which is a phenomenon described in cardiology and post-operative cardiac surgery, is responsible for an increase in morbidity and mortality.
- Trial name
- CoDoRéa (NCT04680728)
- Testing
- collection of biological parameters, collection of echographic parameters, collection of clinical parameters
- Where
- France
- Volunteers
- 185 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Renal Vascular Disease, Nutcracker Syndrome, Renal
Renal Autotransplantation; Case Series
Renal autotransplantation (RAT) is a method of removing a kidney from its place of origin in a patient, repairing it, and transplanting it in another location of the body, generally the iliac fossa of the same patient.RAT is a…
- Conditions
- Renal Vascular Disease, Nutcracker Syndrome, Renal, Pelvic Trauma, Loin Pain-Hematuria Syndrome
- Trial name
- NCT05115812
- Testing
- Pre-Operative Information, Intra-Operative Data, Post-Operative Data (up to discharge)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Methodist Health System
Intra-Abdominal Hypertension, Venous Congestion
Correlation of Ultrasonography Indices of Venous Congestion With Intra-abdominal Pressure in ICU Patients.
The goal of this prospective observational study is to examine the potential association between intra-abdominal pressure and venous congestion as assessed by abdominal ultrasound, in critically ill patients in the Intensive Care…
- Trial name
- NCT06160856
- Testing
- Abdominal ultrasound
- Volunteers
- 84 people
- Sponsor
- National and Kapodistrian University of Athens
Pachychoroid Disease
Choroidal Venous Congestion Following Scleral Buckling - An Imaging Study
This study aims to understand how blood flow at the back of the eye changes over time after this surgery. By studying these changes, the investigators hope to gain insights that could help improve the understanding of other eye…
- Trial name
- SB (NCT07260097)
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore National Eye Centre
Blindness
Determine the Effect of Intraocular Pressure (IOP), Optic Nerve Imaging, Venous Congestion in Volunteers Prone Position 5 Hours
The purpose of this study is to provide data that would give the investigators a better understanding of the physiologic changes that occur and may contribute to post operative blindness.
- Trial name
- NCT00875043
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Inferior Vena Cava Abnormality, Fluid Responsiveness
Transhepatic Echography for Fluid Responsiveness After Cardiovascular Surgery
Fluid expansion in critically ill patients following high risk surgery may induce fluid overload and worse outcome. Several tools have been developped to predict fluid responsiveness in such situation in order to avoid…
- Conditions
- Inferior Vena Cava Abnormality, Fluid Responsiveness, Fluid Overload, Venous Congestion
- Trial name
- THEFRACS (NCT04914455)
- Testing
- Echocardiography and transhepatic inferior vena cava assessment using ultrasound.
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Lille
Pulmonary Hypertension, Cardiorenal Syndrome
Predictive Value of Renal Venous Flow Profiles for Adverse Outcomes in Right Heart Failure
Predictive value of renal venous flow profiles for adverse outcomes in patients with right heart failure
- Conditions
- Pulmonary Hypertension, Cardiorenal Syndrome, Heart Failure
- Trial name
- NCT03039959
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 421 people
- Sponsor
- University of Giessen
Acute Kidney Injury, Acute Kidney Disease
Effect of CVP and IOH on AKI and AKD
This study was aimed to explore the effect of intraoperative venous congestion and intraoperative hypotension (IOH) on acute adverse kidney events, defined as acute kidney injury (AKI) and acute kidney disease (AKD), after…
- Trial name
- NCT05222074
- Testing
- Venous congestion, Introperation hypotension
- Where
- China
- Volunteers
- 5,127 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Septic Shock, Sepsis
Venous Excess Ultrasound for Personalized Resuscitation in Septic Shock
The goal of this pilot clinical trial is to determine if conducting a larger study using venous excess ultrasound (VEXUS) to guide fluid management in patients with septic shock is feasible.
- Conditions
- Septic Shock, Sepsis, Shock, Critical Care, Intensive Care
- Trial name
- VESPER (NCT06696391)
- Testing
- Venous Excess Ultrasound (VEXUS)-Guided Management
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Western University, Canada
Varicose Veins, Venous Reflux
Pelvic Embolisation to Reduce Recurrent Varicose Veins - Recurrent
The aim of this study is to identify whether the treatment of pelvic venous reflux (pelvic embolisation) in females with recurrent leg varicose veins, who have a proven contribution to their leg varicose veins from pelvic venous…
- Conditions
- Varicose Veins, Venous Reflux, Pelvic Congestion Syndrome
- Trial name
- NCT01909024
- Testing
- Coil embolisation, endovenous treatment of leg recurrent varicose veins
- Where
- 2 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- The Whiteley Clinic
Venous Congestion
Changes in Portal Vein Pulsatility Variability During a Tidal Volume Challenge Can Predict Fluid Tolerance
In critically ill patients, appropriate fluid administration is one of the cornerstones of hemodynamic management, as both hypovolemia and fluid overload can negatively impact clinical outcomes.
- Trial name
- SERLU (NCT07131228)
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín