Clinical trials: Venous Insufficiency
Chronic Venous Insufficiency (CVI), Deep Vein Reflux
Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System (INFINITE-US)
Prospective, non-randomized, multicenter pre-market early feasibility study (EFS) to evaluate subjects treated with the BlueLeaf System for the treatment of symptomatic chronic venous insufficiency (CVI) of the lower extremity
- Trial name
- INFINITE-US (NCT04225806)
- Testing
- BlueLeaf® Endovenous Valve Formation System (BlueLeaf System)
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Intervene, Inc.
Venous Insufficiency (Chronic)(Peripheral)
Chronic Venous Insufficiency and Balneotherapy
The aim of this clinical trial is to assess the efficacy of the balneotherapy program (therapeutic orientation: Phlebology) in terms of chronic venous disease improvement and related quality of life, in patients presented with…
- Trial name
- NCT06054737
- Testing
- SPA THERAPY
- Where
- France
- Volunteers
- 64 people
- Sponsor
- CEN Biotech
Chronic Venous Insufficiency
A Feasibility Study of the ReLeaf Catheter System
This study is designed to evaluate the safety and technical feasibility of the ReLeaf Catheter System in the creation of one or more tissue leaflets in the femoral and/or popliteal vein in subjects with chronic venous…
- Trial name
- ReLeaf (NCT02462096)
- Testing
- ReLeaf
- Where
- New Zealand
- Volunteers
- 2 people
- Sponsor
- Intervene, Inc.
Chronic Venous Insufficiency
Investigation of Femoropopliteal In Situ Valve Formation With the InterVene System (INFINITE-Canada)
Prospective, non-randomized, multicenter pre-market feasibility study to evaluate subjects treated with the BlueLeaf System for the treatment of symptomatic CVI of the lower extremity.
- Trial name
- NCT05047302
- Testing
- BlueLeaf Procedure
- Sponsor
- Intervene, Inc.
Chronic Venous Insufficiency
Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study
This is a multi-center series assessment with a planned accrual of 70 patients with diagnosed symptomatic primary GSV insufficiency.
- Trial name
- VEINRESET (NCT05926830)
- Testing
- Sonovein Treatment
- Where
- 4 sites in United States, Austria and 1 more
- Volunteers
- 70 people
- Sponsor
- Theraclion
May-Thurner Syndrome, Deep Vein Thrombosis
Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System
This is a prospective, multi-center, single-arm, non-blinded clinical trial designed to investigate the safety and efficacy of the Vesper DUO Venous Stent System as compared to a pre-defined performance goal (PG) established from…
- Conditions
- May-Thurner Syndrome, Deep Vein Thrombosis, Chronic Venous Insufficiency
- Trial name
- VIVID (NCT04580160)
- Testing
- Duo Venous Stent System
- Where
- 30 sites in United States, Poland
- Volunteers
- 162 people
- Sponsor
- Vesper Medical, Inc.
Venous Leg Ulcer, Venous Ulcer
Tissue Repair Gel in Venous Leg Ulcers in AU/US
The goal of this clinical trial is to learn if TR987 0.1% gel + Standard of Care works better than Standard of Care alone to treat Venous Leg Ulcers (VLUs).
- Conditions
- Venous Leg Ulcer, Venous Ulcer, Venous Stasis Ulcer, Venous Stasis
- Trial name
- TRIVIA (NCT06707103)
- Testing
- TR987 0.1% gel + Standard of Care, Standard of care
- Where
- 12 sites in United States, Australia
- Volunteers
- 312 people
- Sponsor
- TR Therapeutics
Chronic Venous Insufficiency
VAP-PRO-C6. Effectiveness and Tolerability of Venoactive Drugs in Combination Therapy in Patients With CVD (CEAP C6)
The VAP-PRO-C6 is a Russian multicenter observational program to be implemented at the routine visits and assessments. The program will include patients with chronic venous disease of CEAP classes C6.
- Trial name
- VAP-PRO-C6 (NCT04757766)
- Testing
- in daily everyday routine practice
- Where
- Russia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Servier Russia
Arterio-Venous Fistula, Kidney Failure, Chronic
VALUE- Vascular Access Laminate eUropean Experience. A Post Market Surveillance Study to Assess the Safety and Effectiveness of VasQ
This is a prospective single arm study enrolling patients who are scheduled for creation of a new Brachiocephalic or Radiocephalic AV fistula.
- Conditions
- Arterio-Venous Fistula, Kidney Failure, Chronic, Kidney Diseases, Renal Failure Chronic
- Trial name
- VALUE (NCT03246984)
- Testing
- VasQ
- Where
- 11 sites in France, Germany and 2 more
- Volunteers
- 80 people
- Sponsor
- Laminate Medical Technologies
Venous Leg Ulcer, Venous Insufficiency of Leg
Preliminary Investigation of a Smart Compression Therapy Prototype
Compression wraps treat venous leg ulcers when applied correctly. Often, clinicians apply the wraps at the wrong compression, or the wrap loosens, stopping clinical benefits.
- Trial name
- PRESUF-VLU (NCT05610241)
- Testing
- Compression Therapy System Prototype, Standard Compression
- Where
- Ireland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- DeRoyal Industries, Inc.
Chronic Venous Insufficiency, CVI
Clinical Study to Assess the Safety and Efficacy of Mechanochemical Ablation With Flebogrif in Patients With Great Saphenous Vein Insufficiency
The objective of the study is to collect clinical data of patients in whom Flebogrif® will have been used for mechanochemical ablation of incompetent veins in the follow-up period, as related to the safety, clinical…
- Trial name
- POLFLEB (NCT04558957)
- Testing
- FLEBOGRIF
- Where
- 4 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Balton Sp.zo.o.
Multiple Myeloma, Myelodysplastic Syndromes
A Study of Special Use Results Surveillance of Revlimid 5mg Capsules
To understand the safety and efficacy of Revlimid® 5 mg Capsules (hereinafter referred to as Revlimid) in all patients who are treated with it under the actual condition of use pursuant to the conditions of approval. 1.
- Trial name
- NCT02921802
- Where
- Japan
- Volunteers
- 4,626 people
- Sponsor
- Celgene
Multiple Myeloma
A Safety and Efficacy Study of Revlimid® 5 mg Capsules in Patients With Relapsed or Refractory Multiple Myeloma Who Have Received Long-term Treatment With it Under the Actual Condition of Use
To understand the safety and efficacy of Revlimid® 5 mg Capsules (hereinafter referred to as Revlimid) in patients with "relapsed or refractory multiple myeloma" (hereinafter referred to as "relapsed or refractory MM") who have…
- Trial name
- NCT02922543
- Where
- Japan
- Volunteers
- 361 people
- Sponsor
- Celgene
Chronic Venous Insufficiency
Venclose RF Ablation System for the Treatment of IPVs
A feasibility study conducted in patients with incompetent (i.e. refluxing) perforator veins were treated using the Venclose RF Ablation System.
- Trial name
- NCT04386785
- Testing
- Radiofrequency (RF) Thermal Ablation of Incompetent Perforator Veins
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Venclose, Inc.
Stasis Dermatitis
Study Evaluating Efficacy and Safety of Crisaborole in Adults With Stasis Dermatitis
This is a Phase 2a, randomized, double blind, vehicle controlled, parallel group, proof of concept study that will include participants with stasis dermatitis without active skin ulceration, who will receive crisaborole ointment…
- Trial name
- NCT04091087
- Testing
- crisaborole ointment, vehicle ointment
- Where
- 4 sites in United States
- Volunteers
- 66 people
- Sponsor
- Pfizer
Chronic Venous Insufficiency
EU Post Market Clinical Follow-Up Study of the Venclose System for Saphenous Vein Incompetence
This is a prospective, non-randomized study in which patients who meet eligibility criteria and consent to participate will undergo a minimally invasive procedure using radiofrequency (RF) energy for ablation of the great…
- Trial name
- NCT04236245
- Testing
- Venclose RF System
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Venclose, Inc.
Venous Insufficiency
A Study Evaluating ClariVein With a Sclerosing Agent for the Treatment of Venous Insufficiency
VICARES is a prospective randomized, controlled, multi-center, double blind study treating venous insufficiency associated with incompetent saphenous veins with 1% and 3% Sodium Tetradecyl Sulfate (STS) solution utilizing the…
- Trial name
- VICARES (NCT03311269)
- Testing
- ClariVein RES, Sodium Tetradecyl Sulfate 1% Injection, Sodium Tetradecyl Sulfate 3% Injection
- Where
- 5 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Vascular Insights, LLC
Venous Leg Ulcer
Effect of VarIthena on Wound Healing in Venous Leg Ulcers (VLU)
A 12 month, multicenter, open-label registry to observe chronic venous insufficiency resulting in VLU treated with Varithena.
- Trial name
- VIEW-VLU (NCT03257254)
- Testing
- Varithena
- Where
- 14 sites in United States, Canada
- Volunteers
- 76 people
- Sponsor
- Boston Scientific Corporation
Chronic Venous Insufficiency
Feasibility of the InnoVein Valve and Delivery System for Chronic Venous Insufficiency
This objective of this feasibility study is to evaluate the safety of the InnoVein Valve and Delivery System for treatment of chronic venous insufficiency.
- Trial name
- NCT04253301
- Testing
- InnoVein Valve Treatment
- Where
- 3 sites in Australia
- Volunteers
- 5 people
- Sponsor
- InnoVein
Chronic Venous Insufficiency
SeCure Endovenous Laser Treatment Study
The VenaCure EVLT 400 µm Fiber Kit is currently marketed for the treatment of varicose veins. AngioDynamics, Inc., the company that manufacturers the VenaCure device, is sponsoring this study to assess the safety and…
- Trial name
- SeCure (NCT02215369)
- Testing
- VenaCure EVLT 400 µm fiber Procedure Kit
- Where
- 7 sites in United States
- Volunteers
- 112 people
- Sponsor
- Angiodynamics, Inc.