Clinical trials: Venous Insufficiency
Venous Insufficiency
Tolerability of Antistax® in Patients Suffering From Chronic Venous Insufficiency (CVI)
Main objective: Safety and tolerability of Antistax® film coated tablets Secondary objective: Effect of Antistax® film coated tablets on subjective symptoms of chronic venous insufficiency
- Trial name
- NCT02184234
- Testing
- Antistax film coated tablets
- Volunteers
- 65 people
- Sponsor
- Boehringer Ingelheim
Venous Insufficiency
Assess the Efficacy and Tolerability of Antistax Film-coated Tablets in Patients With Chronic Venous Insufficiency
To assess the efficacy and tolerability of Antistax film coated tablets in patients with chronic venous insufficiency (CVI, CEAP Classification: Clinical class 3 and 4a).
- Trial name
- NCT00855179
- Testing
- Red vine leaf extract (AS 195)
- Where
- 20 sites in Germany
- Volunteers
- 250 people
- Sponsor
- Boehringer Ingelheim
Venous Insufficiency
Efficacy and Tolerability CVI (A 12-week, Double-blind, Randomised, Placebo-controlled, Multicentre Trial (CVI)
To determine efficacy and tolerability of Antistax 360 mg tablets in chronic venous insufficiency linked to edema (swelling) and subjective symptoms
- Trial name
- NCT00292435
- Testing
- Read vine leaf extract (AS 195)
- Where
- 16 sites in Austria, Czechia and 1 more
- Volunteers
- 202 people
- Sponsor
- Boehringer Ingelheim
Central Venous Pressure
Comparison of a Non-Invasive Central Venous Pressure Device and Physical Examination in Patients With Chronic Kidney Disease
The primary objective of this study is to determine whether a correlation exists between the Mespere Non-Invasive Central Venous Pressure (NICVP) device for measuring central venous pressure (CVP), and assessment of CVP via…
- Trial name
- NCT01243515
- Testing
- Non-Invasive Central Venous Pressure monitor, Physical examination of jugular vein
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mespere Lifesciences Inc.
Venous Insufficiency
Feasibility, Efficacy, and Safety of Venous Ulcer Treatment Using a Hand Plasma Generator (PlasmaDerm) Chronisch venöser Ulzerationen (PlasmaDerm)
The purpose of this study is to prove the safety and efficacy of plasma as an add-on treatment in combination with conventional treatment in cases of chronical venous Ulcus cruris.
- Trial name
- NCT01415622
- Testing
- PlasmaDerm, standard care of Ulcera crurum
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Cinogy GmbH
Varicose Veins, Venous Insufficiency
Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous Vein
This is a multi center, randomized, comparison study using two already cleared methods of treatment of the great saphenous vein (GSV).
- Trial name
- RECoN (NCT01173419)
- Testing
- VNUS RF ClosureFAST, VenaCure EVLT NeverTouch
- Where
- 6 sites in United States
- Sponsor
- Angiodynamics, Inc.
Chronic Cerebral Spinal Venous Insufficiency
Venous Obstruction in Neurodegenerative Disorders Research Registry
To establish if there are venous obstructions in patients with neurodegenerative disorders
- Trial name
- NCT01593358
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Synergy Health Concepts, Inc.
Chronic Venous Insufficiency, Disease
Study to Evaluate the Efficacy and Tolerability of Venaflon Use in Reducing the Symptoms Caused by Chronic Venous Insufficiency When Compared With Daflon
The objective is to evaluate the effectiveness of the safety of Daflon in decreasing symptoms resulting from chronic venous insufficiency when compared with Daflon.
- Trial name
- NCT01477281
- Testing
- Daflon, Venaflon (Diosmin and Hesperidin)
- Volunteers
- 82 people
- Sponsor
- Laboratório Teuto Brasileiro S/A
Chronic Venous Insufficiency, Hemorrhoids
Efficacy and Tolerability of the Use of Varicell Compared With Daflon
The purpose of this study is to evaluate the efficacy and tolerability of Varicell compared to Daflon, in reducing the symptoms caused by chronic venous insufficiency and hemorrhoidal syndrome.
- Trial name
- NCT01321619
- Testing
- Daflon
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- Vidfarma Indústria de Medicamentos Ltda.
Venous Insufficiency
Safety and Efficacy of the External Synchronized Vein Valve (ESVV) in Treatment of Chronic Venous Insufficiency (CVI)
The External Synchronized Vein Valve (ESVV), is intended for the treatment of Chronic Venous Insufficiency (CVI), incorporates an external apparatus that is aimed to replace the one-way venous valve and a sensor that identifies…
- Trial name
- NCT01346553
- Testing
- ESVV device
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- GB-Veintech
Venous Insufficiency
Comparative Efficacy of Two Preparations of the Association Diosmin (450 mg) + Hesperidin (50 mg) in the Treatment of Chronic Venous Insufficiency (CVI)
It is hoped that with the use of medication, occurs improvement of the CVI parameters, such as edema, pain, night cramps, functional discomfort, heavy feeling and that the drug test is non-inferior than the comparator.
- Trial name
- NCT01110512
- Testing
- Flavonid, Daflon
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Azidus Brasil
Venous Stasis Ulcers
Study of Thymosin Beta 4 in Patients With Venous Stasis Ulcers
The purpose of this study is to evaluate the safety, tolerability and effectiveness of Thymosin Beta 4 administered topically in patients with Venous Stasis ulcers
- Trial name
- SSVS (NCT00832091)
- Testing
- Thymosin Beta 4
- Where
- 8 sites in Italy, Poland
- Volunteers
- 72 people
- Sponsor
- RegeneRx Biopharmaceuticals, Inc.
Venous Insufficiency
Efficacy and Safety of the Use of Venocur Triplex® in Patients With Chronic Venous Insufficiency
The purpose of this study is to assess the therapeutic efficacy and safety of Venocur Triplex®, administered BID for 60 days in patients with Chronic Venous Insufficiency rated between CEAP 2 and 4, in comparison to a Placebo…
- Trial name
- NCT00835822
- Testing
- Venocur Triplex®
- Where
- 4 sites in Brazil
- Volunteers
- 216 people
- Sponsor
- Abbott
Venous Insufficiency
Compression Device Safety Study
To evaluate the safety of the Compression Device to subjects with venous insufficiency and oedema.
- Trial name
- NCT00732823
- Testing
- Prototype device(unnamed)-A battery operated inflatable pneumatic cuffs
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- ConvaTec Inc.
Venous Insufficiency, Diabetes
Evaluation of DermStream(tm) - an Irrigation Product for Chronic Wound Management
The primary purpose of this study is to evaluate the safety of DermaStream(tm) in the management of chronic wounds. Other goals of this study are to gain feedback from patients and healthcare providers on the ease of use (the…
- Trial name
- NCT00310752
- Testing
- DermaStream(tm) application and Streaming of Saline
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- EnzySurge
Venous Insufficiency, Leg Ulcer
The Evaluation of OrCel for the Treatment of Venous Ulcers
This study was designed to confirm the clinical benefits and safety of OrCel in the treatment of venous ulcers. OrCel and standard care are compared to standard care alone.
- Trial name
- NCT00270972
- Testing
- Bilayered Cellular Matrix (OrCel)
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Ortec International