Clinical trials: Venous Insufficiency
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
A Tissue Sparing, Laser Assisted Penile Prosthesis Implantation Technique
A surgical technique using laser assisted penile prosthesis implantation
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Due to Arterial Disease, Erectile Dysfunction Due to Arterial Insufficiency
- Trial name
- TSLA (NCT06743048)
- Testing
- Tissue Sparing Laser Implantation
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Renal Insufficiency
Colour Coded Duplex Ultrasound of Native Arterio-venous Fistula for Haemodialysis With Venous Pressure Measurement Using Controlled Compression Ultrasound as a Predictor for Shunt Maturation in the Early Postoperative Phase
Prospective observational ultrasound study of native arterio-venous fistula for haemodialysis with venous pressure measurement using controlled compression ultrasound.
- Trial name
- NCT01001000
- Testing
- Ultrasound (Pressure measurement)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
End Stage Renal Disease, Vascular Access Patency
Determine the Safety/Efficacy of Ticagrelor for Maintaining Patency of Arterio-Venous Fistulae Created for Hemodialysis
This study is a randomized, placebo-controlled, single blind clinical trial. Seventy patients with ESRD on chronic HD and a functioning AVF will be recruited.
- Trial name
- NCT02335099
- Testing
- ticagrelor
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Virginia
Venous Thromboembolic Disease, Kidney Failure, Chronic
Anticoagulation Strategies for Acute Venous Thromboembolism in Patients With End-Stage Renal Disease Using USRDS Data
Patients with end stage renal disease (ESRD) are at significantly increased risk of thrombosis and bleeding relative to those with normal renal function which makes anticoagulation particularly challenging.
- Trial name
- NCT04818151
- Testing
- Warfarin, Apixaban
- Where
- United States
- Volunteers
- 14,914 people
- Sponsor
- Johns Hopkins University
Rhabdomyolysis, Renal Failure
Myoglobin Removal by High Cut-off CVVHD
A high cut-off dialyzer (septeX) is tested for the removal of myoglobin which is not efficiently removed by standard high flux dialysis membranes.
- Trial name
- HicoRhabdo (NCT01467180)
- Testing
- septeX, HF CVVH
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Vantive Health LLC
Chronic Venous Insufficiency, CVI, Chronic Venous Insufficiency C2 or Higher
Reducing Skin Tone Inequities in Chronic Venous Insufficiency
The aim of this project is to define assessment criteria for chronic venous insufficiency (CVI) in people with dark skin tones. It will inform future interventions and modifications to practice for the assessment of CVI in people…
- Conditions
- Chronic Venous Insufficiency, CVI, Chronic Venous Insufficiency C2 or Higher, Chronic Venous Disease of Lower Limbs, Venous Leg Ulcer (VLU)
- Trial name
- NCT06798766
- Where
- 2 sites in United Kingdom
- Volunteers
- 51 people
- Sponsor
- King's College London
Chronic Venous Insufficiency
Clinical Trial of Aesculus Hippocastanum and Associations Versus Diosmina and Hesperidina in Chronic Venous Insuficiency
To demonstrate the clinical non-inferiority of efficacy between Aesculus hippocastanum, Polygonum acre, Smilax Pepyracea, Rutin and Diosmin 450mg and Hesperidin 50mg tablets in the improvement of lower limb symptoms assessed by…
- Trial name
- NCT06579482
- Testing
- Aesculus hippocastanum, and associations
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Fundação Educacional Serra dos Órgãos
Trauma (Including Fractures), Trauma Patients
Renal and Hepatic Abnormal Doppler Patterns in Trauma
The goal of this observational study is to learn about renal and hepatic blood flow abnormalities detected by bedside ultrasound in adult patients admitted to the intensive care unit (ICU) following major trauma.
- Conditions
- Trauma (Including Fractures), Trauma Patients, Kidney Disease, Hypovolemia
- Trial name
- RECREANT (NCT07492511)
- Testing
- Point of care ultrasound
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Azienda Usl di Bologna
End Stage Kidney Disease (ESRD)
Effect of the Amplifi™ Vein Dilation System on Outflow Vein Dilation and AV Fistula Maturation (AMPLIFI-1)
The AMPLIFI-1 Study is a prospective, multicenter pivotal clinical trial designed to evaluate the safety and effectiveness of the Amplifi™ Vein Dilation System in patients requiring distal arteriovenous fistula (AVF) creation for…
- Trial name
- AMPLIFI-1 (NCT07211035)
- Testing
- The Amplifi System is a temporary extracorporeal blood pump designed to deliver controlled flow through a peripheral vein for 24-72 hours prior to AVF creation., Standard of Care (AVF creation)
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Amplifi Vascular, Inc.
Liver Cirrhosis
Comparing a Direct Versus an Indirect Approach to Measuring the Portalsytemic Pressure Gradients
The objective of this study is to evaluate the correlation of the calculated portosystemic pressure gradient (PPG) obtained by direct portal and hepatic pressure measurements with the EchoTip® Insight™ and indirect portal vein…
- Trial name
- NCT04987034
- Testing
- EchoTip® Insight™
- Where
- 3 sites in Belgium, Netherlands and 1 more
- Volunteers
- 35 people
- Sponsor
- Cook Research Incorporated
Shock
High Volume Veno-venous Hemofiltration Versus Standard Care for Post-cardiac Surgery Shock
This study seeks to determine if early continuous High Volume Veno-venous Hemofiltration (HVHF) reduces 30-day all cause mortality in post-cardiac surgery patients developing shock requiring high doses catecholamines.
- Trial name
- HEROICS (NCT01077349)
- Testing
- high volume hemofiltration, standard care
- Where
- France
- Volunteers
- 226 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dialysis Access Malfunction, End Stage Renal Failure on Dialysis
MAgicTouch™ Intervention Leap for Dialysis Access (MATILDA) Trial
For patients with End Stage Renal Failure (ESRF), the surgical creation of an Autogenous Arteriovenous Fistula (AVF) or Autogenous Arteriovenous Graft (AVG) is the recognised standard for providing vascular access.
- Conditions
- Dialysis Access Malfunction, End Stage Renal Failure on Dialysis, End Stage Renal Disease, Fistulas Arteriovenous
- Trial name
- MATILDA (NCT04698512)
- Testing
- AVFistuloplasty with Sirolimus coated balloon
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Singapore General Hospital
Chronic Venous Disease
Clinical Trial to Assess the Efficacy of µSmin® Plus
This study evaluates treatment with the dietary supplement µSmin® Plus in a group of patients suffering from chronic venous insufficiency in comparison with a similarly-sized group of patients receiving placebo evaluated by…
- Trial name
- NCT04101201
- Testing
- µSmin® Plus
- Where
- Romania
- Volunteers
- 73 people
- Sponsor
- Giellepi S.p.A
Venous Insufficiency
Feasibility, Efficacy, and Safety of Venous Ulcer Treatment Using a Hand Plasma Generator (PlasmaDerm) Chronisch venöser Ulzerationen (PlasmaDerm)
The purpose of this study is to prove the safety and efficacy of plasma as an add-on treatment in combination with conventional treatment in cases of chronical venous Ulcus cruris.
- Trial name
- NCT01415622
- Testing
- PlasmaDerm, standard care of Ulcera crurum
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Cinogy GmbH
Preeclampsia, Acute Kidney Injury
Accuracy of Venous Excess Ultrasound Score at Hospital Admission to Predict Acute Kidney Injury
To evaluate diagnostic accuracy of venous excess ultrasound score to predict acute kidney injury
- Trial name
- NCT07040696
- Testing
- Venous excess ultrasound score (VEXUS)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Venous Obstruction
RECANA OUS - Recana Thrombectomy Catheter System for Venous Obstruction and Occlusion Study (RECANA-OUS-IRL)
The goal of this clinical investigation is to learn if the Recana Thrombectomy Catheter System can treat chronic venous obstruction and occlusion in participants with symptomatic postthrombotic venous inflow/outflow obstruction.
- Trial name
- NCT07095660
- Testing
- Recana procedure
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- Intervene, Inc.
Steal Syndrome, Chronic Kidney Diseases
Hemodynamic Assessment of Distal Revascularization Interval Ligation
Our study seeks to define the effect of each component of the distal revascularization interval ligation (DRIL) procedure on the in vivo distal blood pressure of patients with ischemic steal, and to determine whether the interval…
- Conditions
- Steal Syndrome, Chronic Kidney Diseases, Arterio-Venous Fistula
- Trial name
- DRIL (NCT03054623)
- Testing
- DRIL procedure
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- University of South Florida
Chronic Venous Insufficiency, Lipedema
Plantar Pressure Analysis and Foot Biomechanics in Lipedema and Chronic Venous Disease
Chronic venous disease (CVD) are common vascular pathology characterized by a wide spectrum of clinical manifestations occurring with symptoms and/or signs that vary in type and severity.
- Trial name
- NCT06238791
- Testing
- Presence of foot deformity, ankle range of motion, foot posture, local tissue water percentage, and foot pressure distribution will be evaluated in patients with chronic venous disease.
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Hacettepe University
Venous Leg Ulcer, Venous Ulcer
Tissue Repair Gel in Venous Leg Ulcers (US)
The goal of this clinical trial is to learn if TR987 0.1% gel + Standard of Care works better than Standard of Care alone to treat Venous Leg Ulcers (VLUs).
- Conditions
- Venous Leg Ulcer, Venous Ulcer, Venous Stasis Ulcer, Venous Stasis
- Trial name
- TRIVIA (NCT06707090)
- Testing
- TR987 0.1% gel + Standard of Care, Standard of care
- Where
- 33 sites in United States
- Volunteers
- 312 people
- Sponsor
- TR Therapeutics
Nonthrombotic Iliac Vein Lesions, Pelvic Congestive Syndrome
Comparative Study Between Isolated Iliac Vein Stenting Versus Concomitant Iliac Vein Stenting With Pelvic Vein Embolization in Patients With Pelvic Venous Insufficiency Secondary to Nonthrombotic Iliac Vein Lesions
The aim of the study is to compare between Isolated Iliac vein stenting vs Concomitant Iliac vein stenting with pelvic vein embolization in patients with Pelvic Venous Insufficiency secondary to Nonthrombotic iliac vein lesions
- Trial name
- NCT06311669
- Testing
- iliac vein stenting, pelvic vein embolization
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University