Clinical trials: Venous Insufficiency
Total Knee Arthroplasty, Venous Insufficiency of Leg
Efficacy of Diosmin and Hesperidin on Early Rehabilitation After Total Knee Arthroplasty
The goal of this clinical trial is to find out the efficacy of diosmin and hesperidin on postoperative early rehabilitation after primary total knee arthroplasty.
- Trial name
- NCT06753448
- Testing
- Diosmin and Hesperidin Combination
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people
- Sponsor
- Ankara Etlik City Hospital
Varicose Veins, Chronic Venous Disorder
First- or Second- Class Compression Hosiery After Endovenous Laser With Sclerotherapy and Ambulatory Phlebectomy
Investigators hypothesize that first class compression therapy during the postoperative period will improve patient adherence due to easier application and reduced discomfort.
- Conditions
- Varicose Veins, Chronic Venous Disorder, Chronic Venous Insufficiency (CVI), Venous Reflux
- Trial name
- FISCHER (NCT06913764)
- Testing
- class I compression stockings of the RAL-GZ 387 standard: 1 month using, class II compression stockings of the RAL-GZ 387 standard: 1 month using
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Moscow City Hospital named after A.K. Eramishantsev
Varicose Veins of Lower Limb, Venous Insufficiency of Leg
Clinical Outcomes, Safety, and Cost-Effectiveness Analysis of Two Catheters (Xianrui Da and Medtronic) in Radiofrequency Ablation for Varicose Veins
This study aims to systematically compare the clinical efficacy (venous closure rate and symptom relief rate), safety (perioperative and postoperative complications), and cost-effectiveness (direct medical costs) of domestic…
- Conditions
- Varicose Veins of Lower Limb, Venous Insufficiency of Leg, Vascular Disease，Peripheral
- Trial name
- NCT07046286
- Testing
- Compare the two brands of radiofrequency ablation catheters for the treatment of lower limb varicose veins.
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Chronic Venous Insufficiency, Chronic Venous Thrombosis
Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous Disease
Chronic obstruction of the iliac veins or inferior vena cava can occur as a result of deep vein thrombosis (DVT), or due to extrinsic compression in non-thrombotic iliac vein lesions (NIVLs).
- Conditions
- Chronic Venous Insufficiency, Chronic Venous Thrombosis, Iliac Vein Stenosis, Iliac Vein Obstruction
- Trial name
- BEST (NCT05622500)
- Testing
- Deep venous stenting, Best medical therapy
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Imperial College London
Chronic Venous Insufficiency
Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study
This is a multi-center series assessment with a planned accrual of 70 patients with diagnosed symptomatic primary GSV insufficiency.
- Trial name
- VEINRESET (NCT05926830)
- Testing
- Sonovein Treatment
- Where
- 4 sites in United States, Austria and 1 more
- Volunteers
- 70 people
- Sponsor
- Theraclion
Varicose Veins, Chronic Venous Insufficiency
Elastic Compression Stockings and Varicose Veins Recurrence
Hypothesis. Regular using of Class 1 below-knee graduated compression stockings (RAL GZ 387 standard) compared to the absence of elastic compression will reduce the risk of clinically significant varicose veins recurrence at 12…
- Trial name
- ECOS-VVR (NCT04231942)
- Testing
- Graduated Compression Stocking: continuous using, Graduated Compression Stocking: intermittent using
- Where
- 3 sites in Russia
- Volunteers
- 319 people
- Sponsor
- Pirogov Russian National Research Medical University
Chronic Venous Insufficiency
Long-term Effects of Inspiratory Muscle Training in Chronic Venous Insufficiency
The long-term effectiveness of inspiratory muscle training, which is known in the literature to help venous return by increasing the pump effect of the diaphragm muscle, remains unclear in individuals with chronic venous…
- Trial name
- NCT05982405
- Testing
- Training group: Inspiratory muscle training, Control group: Thoracic expansion exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Democracy University
May-Thurner Syndrome, Deep Vein Thrombosis
Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System
This is a prospective, multi-center, single-arm, non-blinded clinical trial designed to investigate the safety and efficacy of the Vesper DUO Venous Stent System as compared to a pre-defined performance goal (PG) established from…
- Conditions
- May-Thurner Syndrome, Deep Vein Thrombosis, Chronic Venous Insufficiency
- Trial name
- VIVID (NCT04580160)
- Testing
- Duo Venous Stent System
- Where
- 30 sites in United States, Poland
- Volunteers
- 162 people
- Sponsor
- Vesper Medical, Inc.
Chronic Venous Insufficiency
The Effect of Inelastic Compression System on Quality of Life in People With Chronic Venous Insufficiency
The purpose of this protocol is to measure the effect of the use of an inelastic compression system (ICS) on quality of life (QOL) in patients with chronic venous insufficiency (CVI) who have demonstrated limited or no compliance…
- Trial name
- NCT05051540
- Testing
- Sigvaris Compreflex Inelastic Compression Wrap
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Venous Leg Ulcer, Venous Ulcer
Tissue Repair Gel in Venous Leg Ulcers in AU/US
The goal of this clinical trial is to learn if TR987 0.1% gel + Standard of Care works better than Standard of Care alone to treat Venous Leg Ulcers (VLUs).
- Conditions
- Venous Leg Ulcer, Venous Ulcer, Venous Stasis Ulcer, Venous Stasis
- Trial name
- TRIVIA (NCT06707103)
- Testing
- TR987 0.1% gel + Standard of Care, Standard of care
- Where
- 12 sites in United States, Australia
- Volunteers
- 312 people
- Sponsor
- TR Therapeutics
Deep Venous Insufficiency (Diagnosis)
The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis Study
A prospective, non blinded, single arm, multicenter study designed to assess the safety and effectiveness of the bioprosthetic, VenoValve, which is surgically implanted into the deep venous system for treatment of patients with…
- Trial name
- SAVVE (NCT04943172)
- Testing
- Hancock-Jaffe bioprosthetic venous valve (VenoValve®)
- Where
- 29 sites in United States
- Volunteers
- 75 people
- Sponsor
- Hancock Jaffe Laboratiores, Inc
Fractures, Bone, CKD Stage 4
The Effect of Prophylactic Anticoagulation on Major Bleeding Events in Hospitalized Chronic Kidney Disease and Lower Limb Fracture Patients.
the risk of bleeding may be greater than the benefit of antithrombotic protection when prophylactically anticoagulating a patient with a lower limb fracture and advanced CKD.
- Conditions
- Fractures, Bone, CKD Stage 4, CKD Stage 3, CKD Stage 5
- Trial name
- FAA (NCT06795698)
- Testing
- Enoxaparin
- Where
- Mexico
- Volunteers
- 61 people
- Sponsor
- Hospital Civil de Guadalajara
Steal Syndrome, Chronic Kidney Diseases
Hemodynamic Assessment of Distal Revascularization Interval Ligation
Our study seeks to define the effect of each component of the distal revascularization interval ligation (DRIL) procedure on the in vivo distal blood pressure of patients with ischemic steal, and to determine whether the interval…
- Conditions
- Steal Syndrome, Chronic Kidney Diseases, Arterio-Venous Fistula
- Trial name
- DRIL (NCT03054623)
- Testing
- DRIL procedure
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- University of South Florida
Chronic Venous Insufficiency, CVI
Respiratory Functions, Aerobic Capacity and Quality of Life in Chronic Venous Insufficiency
This study aims to retrospectively examine the dataset obtained from a previously conducted study titled 'Inspiratory muscle training in individuals with chronic venous insufficiency: randomized controlled trial'.
- Trial name
- NCT06785805
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Izmir Democracy University
Chronic Venous Insufficiency
Inspiratory Muscle Training in Chronic Venous Diseases
There is insufficient evidence of inspiratory muscle training on venous function, clinical severity, symptoms and functional capacity and quality of life in CVI patients.
- Trial name
- NCT05993650
- Testing
- Inspiratuar Muscle Training Group, Thoracic Expansion Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Democracy University
Pregnancy Related, Pelvic Floor Disorders
Effects of Reformer Pilates in Pregnant Women
Pregnancy is known as a period associated with important physiological and psychological changes in women's lives. There is moderately sufficient evidence in the literature to recommend supplementing prenatal physical activity…
- Conditions
- Pregnancy Related, Pelvic Floor Disorders, Pain, Back, Pain, Neck
- Trial name
- NCT06777771
- Testing
- Reformer pilates exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Chronic Venous Insufficiency
Assessment of the Effect of Spa Therapy on the Quality of Life of Patients with Chronic Venous Insufficiency (NEYRAC)
Evaluation of the effectiveness of a phlebology-oriented spa therapy at 6 months on the quality of life of patients suffering from chronic venous insufficiency of the lower limbs
- Trial name
- NEYRAC (NCT05449743)
- Testing
- Spa therapy
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Le Syndicat Intercommunal pour le Thermalisme et l'Environnement
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
A Tissue Sparing, Laser Assisted Penile Prosthesis Implantation Technique
A surgical technique using laser assisted penile prosthesis implantation
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Due to Arterial Disease, Erectile Dysfunction Due to Arterial Insufficiency
- Trial name
- TSLA (NCT06743048)
- Testing
- Tissue Sparing Laser Implantation
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Chronic Venous Insufficiency, CVI
Adding a Combined Program of Therapeutic Exercise and Self-massage to the Conventional Approach of Compression Stockings and Preventive Measures in Chronic Venous Insufficiency.
The purpose of this study is to evaluate whether the inclusion of a physiotherapy approach in primary care consultation prescribing exercises and teaching self-massage techniques would be well accepted by patients of chronic…
- Trial name
- CVI (NCT06727968)
- Testing
- Compression Stocking, Therapeutic exercise, Self-massage
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- University of Valencia
Varicose Veins, Venous Insufficiency
Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open Surgery
200 patients with insufficient great saphenous veins will be randomized to either radiofrequency ablation or high ligation/stripping (open surgery).
- Trial name
- NCT02397226
- Testing
- Radiofrequency ablation, High ligation/stripping, Radiofrequency ablation catheter
- Where
- 2 sites in Sweden
- Volunteers
- 198 people
- Sponsor
- University Hospital, Linkoeping