Clinical trials: Venous Malformation
Venous Malformation, Low Flow, Anticoagulants
A Study of Direct Oral Anticoagulants in Patients with Painful Venous Malformations with Localized Intravascular Coagulation
There are two parts of the study. In Part 1, the invesitgaotrs want to investigate whether treatment with apixaban improves pain and quality of life in patients with painful venous malformations The participants are randomized to…
- Trial name
- AVA (NCT06729034)
- Testing
- Apixaban (Eliquis)
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Venous Aneurysm Nos, Arteriovenous Malformations
Report of Ten Cases of Venous Aneurysm in Extremities
Venous aneurysms are not common in general, but because of the inherent risk of thrombosis in aneurysms, their timely diagnosis and treatment are recommended in most of the current sources.
- Conditions
- Venous Aneurysm Nos, Arteriovenous Malformations, Vascular Diseases
- Trial name
- NCT06437561
- Where
- Iran
- Volunteers
- 10 people
- Sponsor
- Golestan University of Medical sciences
Venous Malformation
Compare Two Different Sclerosing Agents in the Treatment of Venous Malformations
The purpose of this study is to determine the effectiveness of bleomycin, fibrovein and bleomycin and fibrovein in the treatment of venous malformation.
- Trial name
- NCT01347294
- Testing
- Bleomycin, Fibrovein, Bleomycin + Fibrovein
- Where
- Norway
- Volunteers
- 135 people
- Sponsor
- Oslo University Hospital
Venous Malformation
Electromagnetic Navigation During Ultrasound Guided Foam Sclerotherapy for Venous Malformations
The aim of this study is to evaluate the feasibility of assisted electromagnetic navigation in percutaneous echo-guided sclerotherapy of slow-flow vascular malformations.
- Trial name
- SCLERONAV (NCT04486599)
- Testing
- Electromagnetic Navigation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Venous Malformation
Treatment of Venous Malformation
Vascular malformations are birth defects that happen when different stages of angiogenesis shut down. 44 - 64% of all vascular malformations are venous malformations (VMs). Sclerotherapy is the first treatment line for VMs.
- Trial name
- NCT05586919
- Testing
- Direct Puncture Repair / Ethanol, Direct Puncture Repair / Polidocanol
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Venous Malformation, Lymphatic Malformation
First in Human Trial of Topical VT30 in Pts With Venous/Lymphatic Malformations Assoc With PIK3CA or TEK Gene Mutations
VT30-101 is a 2-part first-in-human trial of topically administered VT30 to subjects with cutaneous venous malformations, lymphatic malformations, or mixed venolymphatic malformations associated with PIK3CA or TEK mutations.
- Conditions
- Venous Malformation, Lymphatic Malformation, Venolymphatic Malformation
- Trial name
- NCT04409145
- Testing
- VT30
- Where
- 15 sites in United States
- Volunteers
- 15 people
- Sponsor
- Venthera, Inc., a BridgeBio company
Vascular Malformations, Vascular Anomaly
Vascular Anomaly Pathology and Genomics Biopsy Study
The purpose of this research is to gather information on the safety and effectiveness of core biopsy of vascular anomalies for clinical pathology and clinical genomics studies.
- Conditions
- Vascular Malformations, Vascular Anomaly, Hemangioma, Arteriovenous Malformations
- Trial name
- NCT04836884
- Testing
- Percutaneous Vascular Anomaly/Malformation Biopsy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Ovary Cancer
Validation of Tie2 as the First Tumour Vascular Response Biomarker for VEGF Inhibitors: VALTIVE1
Tumours require a blood supply to provide them with oxygen and nutrients and to enable spread of cancer through blood vessels to other organs (metastasis).
- Trial name
- VALTIVE1 (NCT04523116)
- Where
- 4 sites in United Kingdom
- Volunteers
- 176 people
- Sponsor
- University of Manchester
Vascular Malformations, Vascular Malformation Peripheral
Influence of Flat-knitted Compression Stockings Class I and II on Venous Malformations
Diseases with vascular malformations are rare and often congenital, affecting patients of all ages. Depending on their extent and localization, they can cause discomfort and, especially if activity is restricted, lead to loss or…
- Conditions
- Vascular Malformations, Vascular Malformation Peripheral, Venous Malformation, Vascular Diseases
- Trial name
- NCT04637997
- Testing
- compression stockings class I, compression stockings class II
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University Hospital Erlangen
Aneurysm, Arteriovenous Malformations
Post Market Clinical Follow-Up for ED Coil / Electro-detach Generator v4
This is a multicenter post-marketing clinical follow-up study to collect safety and performance data in a prospective cohort of patients who will have undergone coil embolization using the ED Coil and ED Detach Generator v4.
- Conditions
- Aneurysm, Arteriovenous Malformations, Arterio-venous Fistula
- Trial name
- NCT03853070
- Testing
- ED Coil / Electro-detach Generator v4
- Where
- 3 sites in Belgium, Germany
- Volunteers
- 100 people
- Sponsor
- Kaneka Corporation
Hemangiomas, Venous Malformations
Airway Vascular Lesions
Controversy exists in the treatment of airway hemangiomas ranging from tracheotomy, various lasers, to open removal, none of which have proven to be a gold standard.
- Conditions
- Hemangiomas, Venous Malformations, Lymphatic Malformations
- Trial name
- NCT00866827
- Testing
- Protocols for Treatment
- Volunteers
- 75 people
- Sponsor
- University of Arkansas
Blue Rubber Bleb Nevus Syndrome, Venous Malformation
Efficacy of Rapamycin (Sirolimus) in the Treatment of BRBNS, Hereditary or Sporadic Venous Malformation
A prospective, nonrandomized, open-label, single-arm clinical trial to study efficacy of rapamycin (sirolimus) in the treatment of Blue Rubber Bleb Nevus Syndrome, hereditary or sporadic venous malformation
- Trial name
- NCT03767660
- Testing
- Rapamycin
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking Union Medical College Hospital
Intracerebral Hemorrhage, Arterio-venous Malformation
Multicenter Validation of the AVICH Score
The primary objective of this multicenter study is to validate the AVICH score in terms of patient outcome prediction in AVM patients with associated ICH. Secondary objectives are the impact of pretreatment of the AVICH score.
- Trial name
- AVICH (NCT02920645)
- Testing
- AVM-related ICH
- Volunteers
- 500 people
- Sponsor
- University of Zurich
Congenital Venous Malformation
Systemic and Local Diffusion of Ethanol After Administration of Ethanol 96% Formulated in a Gel and Ethanol 98% Solution by the Percutaneous Route, in Patients With Congenital Venous Malformations:Pharmacokinetic, Pharmacodynamic and Clinical Study.
Absolute ethanol has been used "off-label" as an unmodified formulation (solution) in Congenital Venous Malformations (CVM). Despite its effectiveness, absolute ethanol appears difficult to handle because of its high diffusion…
- Trial name
- NCT00462462
- Testing
- Ethanol 96% Gel, Ethanol 98% Solution
- Where
- 2 sites in United States, France
- Volunteers
- 32 people
- Sponsor
- Orfagen
Hemangiomas, Vascular Malformations
Diagnosis of Hemangiomas and Vascular Malformations
To develop a non-invasive, simple and affordable, measurement technique to differentiate hemangiomas from subtypes of VMS. The purpose of this study is to determine the best office based diagnositc instrument for differentiating…
- Conditions
- Hemangiomas, Vascular Malformations, Venular Malformations, Venous Malformations
- Trial name
- NCT00577213
- Volunteers
- 56 people
- Sponsor
- University of Arkansas
CCSVI, Chronic Cerebrospinal Venous Insufficiency
Multi-center Registry for CCSVI Testing and Treatment
Patients suspected of CCSVI (chronic cerebrospinal venous insufficiency) may be tested and if appropriate treated with catheter venoplasty by an interventional radiologist in their local community who has been credentialled…
- Conditions
- CCSVI, Chronic Cerebrospinal Venous Insufficiency, Venous Malformations of CNS Draining Veins
- Trial name
- CCSVI (NCT01205633)
- Testing
- venous angioplasty
- Where
- 9 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Hubbard Foundation