Clinical trials: Venous Thromboembolic Event
Thromboembolism, Venous
Evaluation of Chemical Venous Thromboembolism Prophylaxis in Trauma
Venous thromboembolism (VTE) causes up to 100,000 deaths annually. Between 10%-30% of patients die within one month of VTE diagnosis, while survivors remain at increased risk for VTE recurrence or other complications like…
- Trial name
- NCT06025162
- Testing
- enoxaparin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Methodist Health System
Dose Adjustment of Enoxaparin in ICU Patients
Anti-factor Xa Based Venous Thromboembolism Prophylaxis
Introduction: Venous thromboembolism (VTE) in the intensive care unit (ICU) is associated with significant morbidity and mortality therefore prevention is imperative to reduce its burden.
- Trial name
- NCT05221879
- Testing
- Dose adjustment of Enoxaparin in patients with sub-therapuetic (prophylactic) levels of factor 10a
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Meir Medical Center
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Russian Non-Interventional Study on Compliance of Venous Thromboembolism (VTE)
This is a local, prospective, multicenter, non-interventional, observational study. Primary objective is to describe how in "real life" thromboprophylaxis is carried out after the discharge from a hospital in the patients who…
- Trial name
- SOPRANO (NCT01444586)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- Russia
- Volunteers
- 2,293 people
- Sponsor
- Bayer
Placental Vascular Pathologies, Venous Thromboembolism Diseases
Prediction of the Risk of Placental Vascular Pathology and Venous Thromboembolic Disease
Venous thromboembolic (VTE) disease is the first cause of maternal mortality in the world. Some other pregnancy pathologies called Placental Vascular Pathologies (PVP) are linked to VTE by biological thrombophilia and are the…
- Trial name
- AngioPred (NCT00695942)
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hip Fractures, Venous Thromboembolism (VTE)
Delivery and Implementation of a Randomised Crossover Trial on Thrombosis
What is the Study About? The DIRECT study (Delivery and Implementation of a Randomised Crossover Trial on Thrombosis) is a large research project investigating the best way to prevent blood clots (thrombosis) in people who break…
- Trial name
- DIRECT (NCT06937372)
- Testing
- Patients in hospitals allocated to this arm will receive aspirin as their routine thromboprophylaxis after surgery., Low molecular weight heparin (LMWH)
- Where
- United Kingdom
- Volunteers
- 21,194 people
- Sponsor
- Queen Mary University of London
Thromboembolism
A Comparison of Certoparin and Unfractionated Heparin in the Prevention of Thromboembolic Events in Acutely Ill Medical Patients
This study is designed to provide efficacy and safety data for certoparin in the prophylaxis of venous thromboembolism in immobilized, acutely ill medical patients.
- Trial name
- NCT00451412
- Testing
- Certoparin, Unfractionated Heparin
- Where
- Germany
- Volunteers
- 3,254 people
- Sponsor
- Novartis
Sickle Cell Disease, Central Venous Catheter Thrombosis
THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS)
Research Question: In adult SCD patients with CVC, is it feasible and safe to conduct an adequately powered RCT to evaluate the use of rivaroxaban as thromboprophylaxis in this population? Study Design: The study is a vanguard…
- Conditions
- Sickle Cell Disease, Central Venous Catheter Thrombosis, Venous Thromboembolism
- Trial name
- THIS (NCT05033314)
- Testing
- Rivaroxaban 10 MG
- Where
- 3 sites in Canada
- Volunteers
- 4 people
- Sponsor
- University Health Network, Toronto
Postpartum Hemorrhage, Venous Thromboembolism
Timing of Thromboprophylaxis After Postpartum Hemorrhage
Postpartum hemorrhage is a leading cause of maternal morbidity and mortality worldwide. Women who experience severe postpartum hemorrhage are at increased risk of both recurrent bleeding and venous thromboembolism.
- Conditions
- Postpartum Hemorrhage, Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- NCT07689136
- Testing
- Pharmacologic Thromboprophylaxis
- Where
- Tunisia
- Volunteers
- 236 people
- Sponsor
- University Tunis El Manar
Venous Thromboembolism
Prevention of Venous Thromboembolism in Subjects Undergoing Hip Fracture Surgery or Surgery in the Lower Extremities
The study objective is to evaluate the efficacy and safety of oral YM150 for prevention of venous thromboembolism in subjects undergoing hip fracture surgery or surgery in the lower extremities.
- Trial name
- NCT00937911
- Testing
- YM150
- Where
- 8 sites in Japan
- Volunteers
- 101 people
- Sponsor
- Astellas Pharma Inc
COVID-19, Venous Thromboembolism
Prevention of Arteriovenous Thrombotic Events in Critically-Ill COVID-19 Patients Trial
The researchers wanted to learn how to help sick patients who are in the hospital because of COVID-19. They are trying to find out the best way that is safe to stop blood clots that could be dangerous from forming in patients…
- Conditions
- COVID-19, Venous Thromboembolism, Arterial Thrombosis
- Trial name
- COVID-PACT (NCT04409834)
- Testing
- Unfractionated Heparin IV, Enoxaparin 1 mg/kg, Clopidogrel
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- The TIMI Study Group
Venous Thromboembolism, Deep-Vein Thrombosis
Implementing a Tool to Identify Risk for Venous Thromboembolism in Cancer Patients
Cancer increases the risk of deep vein blood clots and clots traveling to the lungs (emboli) which cause morbidity (leg swelling, pain, and shortness of breath), sudden death, delays cancer treatment, and decreases cancer…
- Conditions
- Venous Thromboembolism, Deep-Vein Thrombosis, Pulmonary Embolism, Cancer
- Trial name
- NCT01602432
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Atrial Fibrillation, Cardiac Thrombus
VKORC1 and CYP2C9 Gene Polymorphisms and Warfarin Management
The investigators aimed to use pharmacogenetic information in clinical practise which may lead to rapid, efficient, and safe warfarin dosing in this observational prospective study.
- Conditions
- Atrial Fibrillation, Cardiac Thrombus, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT00970892
- Testing
- Warfarin dose titration
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Ankara University
Thromboembolism
A Study to Compare Health Care Costs Between Apixaban and Low Molecular Weight Heparin in Patients With Venous Thromboembolism and Cancer
The purpose of this study is to evaluate the health care resource utilization and costs associated with treating patients diagnosed with cancer and venous thromboembolism with apixaban or low molecular weight heparin.
- Trial name
- NCT05643885
- Where
- United States
- Volunteers
- 7,304 people
- Sponsor
- Pfizer
Thromboembolism
Factor Xa Inhibitor YM150 for the Prevention of Blood Clot Formation in Veins After Scheduled Hip Replacement (ONYX-2)
The purpose of this study is to find the best possible (optimal) dose (effect versus adverse events) of YM150 to prevent the risk of blood clot formation after scheduled hip replacement surgery.
- Trial name
- NCT00353678
- Testing
- YM150
- Where
- 79 sites in Austria, Bosnia and Herzegovina and 15 more
- Volunteers
- 1,141 people
- Sponsor
- Astellas Pharma Inc
Bariatric Surgery, Anti-Xa Activity
The OAT Trail: The Obesity Anti-Coagulation Thromboprophylaxis Trial.
Blood clots in the legs or lungs (called venous thromboembolism or VTE) are one of the most serious complications after weight loss surgery.
- Conditions
- Bariatric Surgery, Anti-Xa Activity, VTE (Venous Thromboembolism), Obesity & Overweight
- Trial name
- The OAT-RCT (NCT07559643)
- Testing
- Anti-Xa Activity Monitoring, Tinzaparin (Leo), enoxaparin
- Where
- Ireland
- Volunteers
- 180 people
- Sponsor
- University College Dublin
Cardiovascular Diseases, Pulmonary Embolism
Epidemiology of Venous Thrombosis and Pulmonary Embolism
To investigate venous thromboembolism in two carefully conducted prospective epidemiologic studies of African American and white adults -- the Atherosclerosis Risk in Communities (ARIC) Study and the Cardiovascular Health Study…
- Conditions
- Cardiovascular Diseases, Pulmonary Embolism, Venous Thrombosis
- Trial name
- LITE (NCT00005504)
- Volunteers
- 21,680 people
- Sponsor
- University of Minnesota
Venous Thromboembolism
Risk, Predictors, Impact and Outcome of Anticoagulation-associated Abnormal Menstrual Bleeding
This study is an international, multicenter, academically sponsored, observational study, that focusses on fertile female patients with proven symptomatic deep vein thrombosis of the legs (DVT) or acute pulmonary embolism (PE).
- Trial name
- TEAM-VTE (NCT04748393)
- Where
- 7 sites in Austria, France and 4 more
- Volunteers
- 90 people
- Sponsor
- Leiden University Medical Center
Venous Thromboembolic Disease
Comparative Study of the Hemorrhagic Risk in Patients Over 75 Years of Age Taking Enoxaparin
Elderly subjects are at greater risk of thrombophlebitis than the general population, but also of bleeding when anticoagulant therapy is initiated.
- Trial name
- ENOX-VTD-H (NCT05150314)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Strasbourg, France
Deep Venous Thrombosis, Pulmonary Embolism
FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease
This is a multi-center prospective cohort study of patients with first-episode deep venous thrombosis and pulmonary embolism.
- Trial name
- NCT04583878
- Testing
- Blood draw (Visit 1), Blood draw (Visits 2 and 3)
- Where
- 14 sites in United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Deep Vein Thrombosis, Coronary Artery Bypass Surgery
A Study of the Efficacy of Preventive Dosing of Fondaparinux Sodium Versus Placebo for the Prevention of Venous Thromboembolism (VTE) in Patients Undergoing Coronary Bypass Surgery Receiving Routine Mechanical Prophylaxis
This trial is a prospective, single-center Phase II randomized study to demonstrate the superior efficacy of Fondaparinux Sodium subcutaneous injections in patients undergoing CABG surgery (isolated and redo isolated) versus…
- Conditions
- Deep Vein Thrombosis, Coronary Artery Bypass Surgery, Venous Thromboembolism
- Trial name
- NCT00789399
- Testing
- Fondaparinux
- Volunteers
- 78 people
- Sponsor
- Prairie Education and Research Cooperative