Clinical trials: Venous Thromboembolic Event
Venous Thromboembolism (VTE)
Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers
This study is researching an experimental drug called REGN7508 (called "study drug") and will consist of 2 parts: Part 1 and Part 2.
- Trial name
- ROXI-CAT-II (NCT07493304)
- Testing
- REGN7508, Apixaban
- Where
- 13 sites in United States, Bulgaria and 3 more
- Volunteers
- 1,600 people
- Sponsor
- Regeneron Pharmaceuticals
Venous Thromboembolism, Atrial Fibrillation
EUropean Pharmacogenetics of AntiCoagulant Therapy - Warfarin
Rationale: The narrow therapeutic range and wide inter-patient variability in dose requirement make anticoagulation response to coumarin derivatives unpredictable.
- Trial name
- EU-PACT (NCT01119300)
- Testing
- Genotype-guided dosing algorithm, Standard care
- Where
- 3 sites in Sweden, United Kingdom
- Volunteers
- 455 people
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Pulmonary Embolism, Venous Thromboembolism
Risk of Pulmonary and Venous Thromboembolism in Pregnancies After in Vitro Fertilization
Occurrence of venous thromboembolism during in Vitro Fertilization (IVF) pregnancies has been reported in numerous case reports and in two small consecutive series.
- Trial name
- NCT01524393
- Where
- Sweden
- Volunteers
- 140,458 people
- Sponsor
- Danderyd Hospital
Thromboprophylaxis
Apixaban to Prevent Venous Thromboembolism in Ambulatory Lung Cancer Patients Undergoing Systemic Anticancer Treatment
The aim of this trial is to find out if a tablet called apixaban can reduce blood clots in people with lung cancer having chemotherapy or similar treatments.
- Trial name
- THROMBO-STOP (NCT07160686)
- Testing
- Apixaban
- Where
- 8 sites in United Kingdom
- Volunteers
- 1,456 people
- Sponsor
- University of Birmingham
Deep Venous Thrombosis, Pulmonary Embolism
Comparing Enoxaparin to Fondaparinux to Prevent Venous Thromboembolism (VTE) in Bariatric Surgical Patients
This pilot study is designed to determine the feasibility of conducting a randomized clinical trial comparing fondaparinux sodium (Arixtra) once daily with enoxaparin (Lovenox®) twice daily with respect to preventing deep vein…
- Trial name
- NCT00894283
- Testing
- Enoxaparin, Fondaparinux
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Johns Hopkins University
Trauma, Surgery
Lovenox 30 mg Twice Daily (BID) Versus 40 mg Once Daily (QD)
The risk of developing a blood clot occurs in up to 60% of all critical care patients. Many times enoxaparin (or Lovenox) is given to patients who are at a higher risk of developing clots in their legs or lungs.
- Conditions
- Trauma, Surgery, Deep Vein Thrombosis (DVT), Thromboembolic Events
- Trial name
- NCT02342444
- Testing
- Enoxaparin Sodium Injection 30 mg BID, Enoxaparin Sodium Injection 40 mg QD
- Where
- United States
- Volunteers
- 606 people
- Sponsor
- Oregon Health and Science University
Pulmonary Thromboembolism
Computed Tomography CT Venography During Postpartum Venous Thromboembolism
The purpose of this study is to determine whether systematically performing computed tomography (CT) venography (i.e a CT acquisition of the pelvis and of the lower limbs, during the venous phase of opacification) in addition to…
- Trial name
- CTVENPOSTPART (NCT02616991)
- Testing
- computed tomography venography
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hematoma Postoperative, Venous Thromboembolism
Use of Tranexamic Acid in Reduction Mammoplasty
Breast reduction mammoplasty (BRM) is among the most commonly performed procedures in plastic surgery. However, postoperative hematoma is one of the most common complications following BRM.
- Trial name
- TREX-ARM (NCT04947514)
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Cerebral Venous Thrombosis
Efficacy Comparison of Warfarin Versus Rivaroxaban CVT
With regard to Cerebral Venous Thrombosis (CVT) importance as a life threatening disease, specific care is necessary, Known anti-coagulants have limitations.Vitamin K antagonists such as Warfarin, require laboratory monitoring…
- Trial name
- NCT03747081
- Testing
- Rivaroxaban, Warfarin
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Isfahan University of Medical Sciences
Venous Thromboembolism
Eliquis (VTE Treatment and Prevention of Recurrent VTE) rPMS
To assess the real-world safety/effectiveness of Eliquis in Korean venous thromboembolism (VTE) patients and patient characteristics that are associated with bleeding among patients taking Eliquis.
- Trial name
- NCT02546817
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Bristol-Myers Squibb
Venous Thromboembolism, Deep Vein Thrombosis
SToP: Venous Thromboembolism Screening in the Trauma Population
This is a prospective, randomized vanguard trial of trauma patients admitted to the trauma surgery service at Intermountain Medical Center who are deemed to be at high risk for venous thromboembolism.
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Trauma, Multiple
- Trial name
- SToP (NCT02978950)
- Testing
- Duplex ultrasound surveillance, No ultrasound surveillance
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Intermountain Health Care, Inc.
Venous Thromboembolic Disease
Observational Prospectif Monocentric Registry of Patients Suffering From VIE
Patients with an episode of VTE (DVT and / or PE) have a mortality rate of 16-21% at 1 year after diagnosis. Morbidity associated with VTE is marked by the risk of recurrence, estimated at 30% and estimated at 29% after 8 years…
- Trial name
- REMOTEV (NCT02188056)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Crohn Disease, Ulcerative Colitis
SAVES-IBD: Safety & Efficacy of Aspirin vs. Standard of Care for VTE Prophylaxis After IBD Surgery
Aim to determine if aspirin 81 mg orally twice daily is effective and safe as an extended VTE chemoprophylaxis agent after major abdominal surgery for IBD patients.
- Conditions
- Crohn Disease, Ulcerative Colitis, Venous Thromboembolism
- Trial name
- SAVES-IBD (NCT05104229)
- Testing
- Aspirin 81Mg Ec Tab, Standard of Care
- Where
- United States
- Sponsor
- Stefan Holubar MD MS FACS, FASCRS
Obstructive Sleep Apnea, Venous Thrombosis
Obstructive Sleep Apnea and Venous Thromboembolism
There is a clear link between obstructive sleep apnea (OSA) and cardiovascular disease. However, there has been no clear link between OSA and venous thromboembolism (VTE). The objective of this study is to evaluate such a link.
- Conditions
- Obstructive Sleep Apnea, Venous Thrombosis, Pulmonary Embolism, Venous Thromboembolism
- Trial name
- OSAVTE (NCT01051297)
- Volunteers
- 85 people
- Sponsor
- University of Missouri-Columbia
Deep Vein Thrombosis, Venous Thromboembolism
Single Session Percutaneous Mechanical Thrombectomy for the Treatment of Ilio-femoral Deep Vein Thrombosis: A Preliminary Evaluation
Venous thromboembolism (VTE) is a common condition that occurs when a clot develops in one of your veins. It affects 5% of the population and is the third most common circulatory condition after heart attack and stroke.
- Trial name
- SPADE (NCT02066597)
- Testing
- Thrombectomy
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Ottawa Hospital Research Institute
Venous Thromboembolism
Treatment Patterns Among Patients With Venous Thromboembolism in the United States
The purpose of this study is to assess outpatient treatment patterns following hospitalization for venous thromboembolism (VTE). VTE is a condition that occurs when blood clot forms in the vein.
- Trial name
- NCT05795062
- Testing
- apixaban, warfarin
- Where
- United States
- Volunteers
- 13,945 people
- Sponsor
- Pfizer
Peritoneal Metastases, Peritoneal Carcinomatosis
Changes in Coagulation in Colorectal Cancer Patients Undergoing Surgical Treatment
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) has prolonged the survival substantially for selected patients with peritoneal metastases from colorectal cancer.Bleeding and thromboembolic disease…
- Conditions
- Peritoneal Metastases, Peritoneal Carcinomatosis, Colorectal Neoplasms Malignant, Intestinal Neoplasms
- Trial name
- CONTEST (NCT04744688)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Thrombophlebitis
POST (Prospective Observational Superfial Thrombophlebitis)
We performed a national cross-sectional and prospective large epidemiological cohort study in patients with ST. Office- and hospital-based vascular medicine French practitioners enrolled all consecutive patients with a…
- Trial name
- POST (NCT00818688)
- Testing
- compression ultrasonography at 3 months
- Where
- 5 sites in France
- Volunteers
- 844 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cancer, Venous Thromboembolism
Identification of Novel Biomarkers to Aid in the Detection of Occult Cancer in Patients With Venous Thromboembolism
Venous thromboembolism is a common and serious complication in cancer, and is associated with a substantially increased morbidity and mortality. Furthermore, VTE may be the earliest sign of cancer.
- Trial name
- NCT03781531
- Where
- 2 sites in Sweden
- Volunteers
- 1,000 people
- Sponsor
- Danderyd Hospital
Atrial Fibrillation, Thromboembolism, Venous
DOCE Study Interaction Between Direct Oral Anticoagulants and Drug-metabolizing Enzyme Inducers
Aim of the study is to investigate whether the influence of drugs inducing of CYP 3A4 isoenzyme of CYP450 and P-gp transporter significantly affect plasma levels of DOACs in patients with NVAF and venous thromboembolism
- Trial name
- NCT05750680
- Testing
- DOACs
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS