Clinical trials: Venous Thromboembolic Event
COVID-19
Effect of Anticoagulation Therapy on Clinical Outcomes in COVID-19
Patients with moderate to severe COVID-19 present a very high risk of thromboembolic disease.This multicenter, prospective, randomized, event-driven study evaluates rivaroxaban compared with standard of care with…
- Trial name
- COVID-PREVENT (NCT04416048)
- Testing
- Rivaroxaban, Standard Of Care (SOC)
- Where
- 24 sites in Germany
- Volunteers
- 111 people
- Sponsor
- Charite University, Berlin, Germany
Venous Thromboembolism
ICU Venous Thromboembolism Incidence Study in a Chinese Population
Venous thromboembolism (VTE) is one of the major public health problems in Western country. More than 100,000 Americans die each year from VTE.
- Trial name
- NCT01504087
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Pulmonary Embolism
Venous Thromboembolism (VTE) Treatment Study in Japanese Pulmonary Embolism (PE) Patients
The objective of this study is to evaluate the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of rivaroxaban in the treatment of pulmonary embolism (PE) and the prevention of the occurrence and the recurrence…
- Trial name
- NCT01516814
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Unfractionated heparin, Warfarin
- Where
- 31 sites in Japan
- Volunteers
- 40 people
- Sponsor
- Bayer
Cardiovascular Diseases, Pulmonary Embolism
Epidemiology of Venous Thrombosis and Pulmonary Embolism
To investigate venous thromboembolism in two carefully conducted prospective epidemiologic studies of African American and white adults -- the Atherosclerosis Risk in Communities (ARIC) Study and the Cardiovascular Health Study…
- Conditions
- Cardiovascular Diseases, Pulmonary Embolism, Venous Thrombosis
- Trial name
- LITE (NCT00005504)
- Volunteers
- 21,680 people
- Sponsor
- University of Minnesota
Venous Thromboembolism, Pulmonary Embolism
: Pharmacokinetics of Enoxaparin After Coronary Artery Bypass Graft Surgery
To evaluate the pharmacokinetics of thromboprophylactic doses of LMWH enoxaparin in postoperative CABG patients, drug is administered either as a continuous intravenous infusion (CIV) or subcutaneous bolus (SCB) once per 72h.
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Thromboprophylaxis
- Trial name
- NCT02474212
- Testing
- Enoxaparin
- Where
- Finland
- Volunteers
- 85 people
- Sponsor
- Tampere University Hospital
Venous Thromboembolism
Venous Thromboembolism Prophylaxis in Medical and Surgical ICUs in a Single University Hospital
Venous thromboembolism(VTE) is the third most common cardiovascular complication among hospitalized patients, and can even cause death.
- Trial name
- NCT01851239
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Open Fracture of Hip
Rivaroxaban Safety Profile in the Prophylaxis of Venous Thromboembolism After Hip Fracture Surgery
Arterial and venous thromboembolism represents one of the most common preventable health problems. Patients undergoing surgery, especially hip fracture surgery are at high risk for deep vein thromboembolism (VTE) without…
- Trial name
- NCT01509118
- Where
- 7 sites in Thailand
- Volunteers
- 500 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Pulmonary Embolism, Venous Thrombosis
Incidence of Venous Thromboembolic Disease and Portal Vein Thrombosis After Hepatectomy. A Cohort Study.
Observational. Retrospective cohort.
- Conditions
- Pulmonary Embolism, Venous Thrombosis, Portal Thrombosis
- Trial name
- NCT02597218
- Where
- Argentina
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Venous Thromboembolism, Deep Venous Thrombosis
Twice Daily Enoxaparin Prophylaxis in Reconstructive Surgery Patients
Blood clots that form in the extremities (deep venous thrombosis) and lungs (pulmonary embolus) are feared complications of reconstructive surgery.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus
- Trial name
- NCT02687204
- Testing
- Twice daily enoxaparin prophylaxis, Real time dose adjustment
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Utah
Pregnancy Complications, Proteinuria in Pregnancy
Sonoclot to Evaluate Thrombotic Risk in Proteinuric Pregnancy
There is a lack of consensus on whether women with proteinuric kidney disease benefit from prophylactic anticoagulation during pregnancy to reduce the risk of venous thromboembolism.
- Conditions
- Pregnancy Complications, Proteinuria in Pregnancy, Chronic Kidney Diseases, Venous Thromboembolism
- Trial name
- NCT05108389
- Testing
- Viscoelastic haemostasis monitor output
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Venous Thromboembolism
Eliquis Regulatory Post Marketing Surveillance (rPMS)
The objective of this regulatory Post-Marketing Surveillance in Korea is to reconfirm the clinical usefulness of Eliquis through collecting, reviewing, identifying and verifying the safety and effectiveness information about…
- Trial name
- NCT01885585
- Testing
- Apixaban
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Bristol-Myers Squibb
No Condition, Healthy Individuals, No Conditions, Aged 20-64
Evaluating the Hemodynamic Performance of the VenAir Sequential Compression System
The goal of this clinical trial is to learn an Intermittent Pneumatic Compression Device (IPCD), VenAir, effectiveness in healthy adults. The main questions this research aims to answer are: 1.
- Trial name
- NCT07287007
- Testing
- VenAir, SCD700
- Where
- Taiwan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Wellell Inc. Taiwan
Drug Drug Interaction Study
Rivaroxaban Sotorasib Interaction Study
Venous thromboembolic Events (VTEs) are common in lung cancer patients with an incidence of >15%, requiring anticoagulant treatment or prophylaxis.
- Trial name
- ROSIE (NCT06314763)
- Testing
- Rivaroxaban 20mg, Sotorasib 960mg
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Major Non-cardiac Surgeries
A Trial of a Hospital Policy of Tranexamic Acid Use to Reduce Transfusion in Major Non-cardiac Surgery
A Phase IV trial of a hospital policy of Tranexamic acid to reduce transfusion in major non-cardiac surgery.
- Trial name
- TRACTION (NCT04803747)
- Testing
- Tranexamic acid (TXA)
- Where
- 10 sites in Canada
- Volunteers
- 8,421 people
- Sponsor
- University of Manitoba
Atrial Fibrillation, Venous Thromboembolism
Warfarin Patient Self-management Implementation in the US Healthcare System
In the US, patients receiving warfarin therapy are rarely allowed to engage in patient self-management (PSM) which is less burdensome, less expensive, and safer than standard clinic-directed warfarin management.
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Heart Valve Diseases
- Trial name
- NCT04766216
- Testing
- Patient self-management, Usual care provided by anticoagulation providers
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Utah
Deep Vein Thrombosis
Incidence of Venous Thromboembolism in Children Undergoing Elective Neurosurgical Procedures
The purpose of this study is to determine how frequently children undergoing elective neurosurgical procedures develop blood clots in the deep veins of the legs while hospitalized.
- Trial name
- NCT02037607
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Venous Thrombosis, End Stage Renal Failure With Renal Transplant
The Risk of Venous Clotting in Patients After Renal Transplant
Clots that develop in the deep veins of the legs or the lungs can result in pain, heart and lung disease and may lead to death if unrecognized or not treated.
- Conditions
- Venous Thrombosis, End Stage Renal Failure With Renal Transplant, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- REPORT (NCT01413464)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Venous Thromboembolism
Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Knee Replacement Surgery
The primary objective was to demonstrate the dose-response of Semuloparin sodium (AVE5026) for the prevention of Venous Thromboembolism [VTE] in patients undergoing total knee replacement [TKR] surgery.
- Trial name
- TREK (NCT00331838)
- Testing
- Semuloparin sodium, Enoxaparin sodium
- Where
- 19 sites in Argentina, Bulgaria and 17 more
- Volunteers
- 705 people
- Sponsor
- Sanofi
Neoplasms, Venous Thromboembolism
National Evaluation of the Adherence to Recommendations of Venous Thrombo Embolism Treatment in Cancer Patients
Treatment of venous thromboembolism in cancer patients is specific and has been validated in trials that favor the use of LMWH (Low Molecular Weight Heparin) instead of VKA (Vitamin K Antagonist) treatment during 6 months.
- Trial name
- CARMEN (NCT01362933)
- Testing
- VTE treatment in cancer patient description
- Where
- 49 sites in France
- Volunteers
- 502 people
- Sponsor
- Floralis
Venous Thromboembolism, Varicose Veins
THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)
Endovenous interventions are keyhole operations for varicose veins that are carried out from within the vein itself. Varicose veins are enlarged veins close to the surface of the skin.
- Trial name
- THRIVE (NCT05735639)
- Testing
- Dalteparin Sodium, Tinzaparin Sodium, Enoxaparin Sodium
- Where
- United Kingdom
- Volunteers
- 3,175 people
- Sponsor
- Imperial College London