Clinical trials: Venous Thromboembolic Event
Glioma, Malignant
Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients
Glioma is a common brain tumor with a high risk of venous thromboembolism during treatment, especially in the months after surgery.
- Trial name
- NCT06196918
- Testing
- Rivaroxaban 10 MG
- Where
- 8 sites in China
- Volunteers
- 320 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Venous Thrombosis
Evaluation of the Duration of Therapy for Thrombosis in Children
The Kids-DOTT trial is a randomized controlled clinical trial whose primary objective is to evaluate non-inferiority of shortened-duration (6 weeks) versus conventional-duration (3 months) anticoagulation in children with…
- Trial name
- Kids-DOTT (NCT00687882)
- Testing
- Shortened duration (6 weeks) of anticoagulant therapy, Conventional duration (3 months) of anticoagulant therapy, No Intervention
- Where
- 63 sites in United States, Australia and 4 more
- Volunteers
- 532 people
- Sponsor
- Johns Hopkins All Children's Hospital
Venous Thromboembolism
Phase IIa Venous Thromboembolism (VTE) Prevention Study In Total Knee Replacement (TKR)
This study was designed to assess the safety and efficacy of GW813893 in the prophylaxis of VTE following TKR and to provide evidence to enable the selection of the appropriate dose(s) and dose regimen of GW813893 for future…
- Trial name
- NCT00541320
- Testing
- GW813893
- Where
- 8 sites in United States
- Sponsor
- GlaxoSmithKline
Venous Thromboembolism
Optimal Prophylactic Method of Venous Thromboembolism (VTE)
This study is to define the optimal method of prophylaxis for patients with gastrectomy in Korea and the investigators hypothesized only mechanical method would be enough for preventing VTE on perioperative period.
- Trial name
- NCT01448746
- Testing
- low molecular weight heparin
- Where
- South Korea
- Volunteers
- 682 people
- Sponsor
- The Catholic University of Korea
Multiple Myeloma, Venous Thromboembolism
Validation of the 4TS RAM in the Prevention of Venous Thromboembolism in Patients With Plasma Cell Dyscrasias.
Patients with newly diagnosed symptomatic multiple myeloma per IMWG criteria prior to therapy initiation are enrolled in the study.
- Trial name
- ROADMAP-MM (NCT03405571)
- Testing
- No intervention
- Where
- Greece
- Volunteers
- 800 people
- Sponsor
- University of Athens
Venous Thromboembolic Disease, Pulmonary Embolism
CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism
Although pharmacologic and mechanical methods to prevent VTE are safe, effective, cost-effective, and advocated by authoritative guidelines,many studies continue to demonstrate that these preventive methods are significantly…
- Conditions
- Venous Thromboembolic Disease, Pulmonary Embolism, Venous Thromboembolism, Deep Venous Thrombosis
- Trial name
- NCT04211181
- Testing
- The multifaceted interventions, Routine VTE prophylaxis
- Where
- China
- Volunteers
- 5,800 people
- Sponsor
- China-Japan Friendship Hospital
Cerebral Venous Thrombosis
Anticoagulation Combined With Tocilizumab for Interleukin-6 Receptor Inhibition in Acute Cerebral Venous Thrombosis
This study aims to evaluate the efficacy and safety of tocilizumab, an interleukin-6 (IL-6) receptor antagonist, combined with standard anticoagulant therapy compared with standard anticoagulant therapy alone in patients with…
- Trial name
- NCT07801638
- Testing
- Tocilizumab, Standard Treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Capital Medical University
Total Knee Replacement
Safety and Efficacy of TeaRx Xa Factor Direct Inhibitor Versus Enoxaparin as a Venous Thromboembolic Events (VTE) Prevention Following Total Knee Replacement
To evaluate influence of therapy on the following efficacy and safety parameters in different TeaRx dose groups and Enoxaparin group: Total venous thromboembolic events (VTE), which includes confirmed deep venous thrombosis…
- Trial name
- NCT03088358
- Testing
- TeaRx, Enoxaparin
- Where
- 8 sites in Russia
- Volunteers
- 200 people
- Sponsor
- TeaRx LLC
COVID-19, Critical Illness
Risk of Venous Thromboembolism in Critically Ill Patients With Severe COVID-19
Severe COVID-19 patients at a high risk of venous thromboembolism. We studied patients in 2 intensive care units of university hospitals in Barcelona and Badalona, Spain.
- Conditions
- COVID-19, Critical Illness, Venous Thromboembolism, Venous Thromboses
- Trial name
- NCT04374617
- Testing
- Duplex ultrasound and Computed Tomography Angiography
- Where
- 3 sites in Spain
- Volunteers
- 230 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Venous Thromboembolism
Electronic Alert System for Improving Thromboprophylaxis in Hospitalized Medical Patients
The investigators aim to investigate whether a computer-based alert system in the electronic patient chart and order entry system using the Geneva Risk Score as clinical decision support tool to estimate the risk of venous…
- Trial name
- NCT03124017
- Testing
- Electronic alert and the Geneva Risk Score calculation tool issued in the electronic patient chart
- Where
- Switzerland
- Volunteers
- 1,756 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pulmonary Hypertension, Thromboembolism, Pulmonary
Perioperative Portal Vein Pulsatility as a Postoperative Prognostic Indicator in Pulmonary Endarterectomy
The investigators aim to evaluate the utility of portal vein pulsatility as a predictor of the composite outcome of persistent organ dysfunction plus death in patients undergoing elective or urgent pulmonary endarterectomy for…
- Conditions
- Pulmonary Hypertension, Thromboembolism, Pulmonary, Perioperative/Postoperative Complications, Venous Hypertension
- Trial name
- PVP-ETO-CPC (NCT03197792)
- Testing
- All patients
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Blood Disease, Thrombotic Disorder
Examining the Experiences of Children With Blood Disorders
This is a 3-phase mixed methods study design. A literature review (Phase 1) has been completed to determine the areas of exploration and to identify challenges faced and the impact of the blood disorder on pediatric patients.
- Conditions
- Blood Disease, Thrombotic Disorder, Venous Thromboembolism, Hemostatic Disorder
- Trial name
- NCT04600609
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Texas Southwestern Medical Center
Venous Thromboembolism, Deep Vein Thrombosis
RIVAroxaban Versus Low-molecular Weight Heparin in Patients With Lower Limb Trauma Requiring Brace or CASTing
Lower limb trauma requiring immobilization is a very frequent condition that is associated with an increased risk of developing venous thromboembolism (VTE).
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism, Lower Limb Trauma
- Trial name
- RIVACAST (NCT06195540)
- Testing
- Rivaroxaban 10 MG, Low Heparin Molecular Weight
- Where
- 37 sites in France
- Volunteers
- 1,424 people
- Sponsor
- University Hospital, Angers
Deep Venous Thrombosis
Doppler Ultrasound Imaging of Plastic Surgery Patients for DVT Detection
This prospective controlled study examines the use of Doppler ultrasound as a means to screen elective plastic surgery patients for the presence of deep venous blood clots both before and after surgery.
- Trial name
- NCT02123550
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Swanson Center
Women's Health, Blood Coagulation Disorders
The Effect of the Mini-pill on Blood Factors in Women at Increased Risk for Forming Blood Clots
We propose a prospective cohort study to assess the effect of the progesterone only contraceptive pill (minipill) on coagulation parameters known to be associated with risk of thrombosis (blood clots) in women who are at…
- Trial name
- NCT00580424
- Testing
- Norethindrone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Venous Thromboembolism (VTE), Total Joint Arthroplasty
Efficacy of Aspirin in Preventing Venous Thromboembolism
Efficacy of aspirin and enoxaparin in preventing venous tromboembolism was compared after total knee or hip arthroplasty.
- Conditions
- Venous Thromboembolism (VTE), Total Joint Arthroplasty, Total Hip Arthroplasty (THA)
- Trial name
- NCT06635317
- Testing
- Aspirin, enoxaparin
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
DVT - Deep Vein Thrombosis, VTE (Venous Thromboembolism)
Padua Prediction Score for VTE Risk in Thoracic Surgery Patients
The goal of this observational study is to assess the predictive accuracy of the Padua Prediction Score (PPS) for venous thromboembolism (VTE) risk in thoracic surgery patients.
- Trial name
- DVT (NCT06732726)
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- Al-Nahrain University
Lung Cancer, Venous Thromboembolism
Development and Application of a Thrombosis Risk Prediction Model in Lung Cancer Patients Treated With Immune Checkpoint Inhibitors
The purpose of this observational study is to explore the incidence, risk factors, and relationship with therapeutic outcomes of VTE (venous thromboembolism) and ATE (arterial thromboembolism) associated with immune checkpoint…
- Conditions
- Lung Cancer, Venous Thromboembolism, Arterial Thromboembolism, Immune Checkpoint Inhibitors (ICIs)
- Trial name
- NCT06950697
- Where
- 5 sites in China
- Volunteers
- 2,400 people
- Sponsor
- Beijing Chao Yang Hospital
Advanced Cancer, Metastatic Cancer
Prevention of Venous and Arterial Thromboembolism, in Cancer Patients Undergoing Chemotherapy, With a Low Molecular Weight Heparin (Nadroparin Calcium)
In this phase III, multicenter study, 1200 patients with lung, breast, gastrointestinal (stomach, colon-rectum, pancreas), ovarian or head and neck cancer undergoing chemotherapy will be randomly assigned (at the beginning of…
- Trial name
- NCT00951574
- Testing
- Nadroparin calcium
- Where
- 46 sites in Italy
- Volunteers
- 1,166 people
- Sponsor
- Italfarmaco
Deep Vein Thrombosis (DVT)
Improving Emergency Department Testing for Deep Vein Thrombosis
This observational study will use a new way to test for deep vein thrombosis (DVT) of the leg. A DVT is a blood clot in the leg and is a medical problem that can cause swelling, pain, and redness.
- Trial name
- NCT06195787
- Where
- Canada
- Volunteers
- 458 people
- Sponsor
- Dr. Kerstin de Wit