Clinical trials: Venous Thromboembolic Event
Deep Vein Thrombosis
Single Complete Compression Ultrasonography to Rule Out Deep Vein Thrombosis During Pregnancy and Postpartum
The objective of the EDVIGE study is to determine whether a negative single distal and proximal leg veins compression ultrasonography safely rules out the diagnosis of deep vein thrombosis in pregnant and post-partum women with…
- Trial name
- EDVIGE (NCT00740454)
- Testing
- Lower limb veins compression ultrasonography
- Where
- 2 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Brest
Pulmonary Embolism, Chronic Obstructive Pulmonary Disease
Pulmonary Embolism as a Cause of COPD Exacerbations
The primary objective is to demonstrate the clinical benefits of an active strategy for the diagnosis and treatment of PE compared to usual care in patients with unexplained exacerbations of COPD who require hospital admission.
- Trial name
- SLICE (NCT02238639)
- Testing
- Diagnostic and therapeutic strategy: Highly sensitive D-dimer testing and, if positive, multidetector computed tomographic pulmonary angiography (MDCT).
- Where
- 19 sites in Spain
- Volunteers
- 746 people
- Sponsor
- Ministry of Health, Spain
Venous Thromboembolism
EXCLAIM:Extended Prophylaxis for Venous ThromboEmbolism (VTE) in Acutely Ill Medical Patients With Prolonged Immobilization
Primary objective: To demonstrate the superiority of extended VTE prophylaxis with enoxaparin 40mg sc qd for 28 ± 4 days, compared to placebo, both following 10 ± 4 days of initial treatment with enoxaparin 40mg sc qd Secondary…
- Trial name
- NCT00077753
- Testing
- enoxaparin sodium
- Where
- 20 sites in United States, Argentina and 18 more
- Volunteers
- 4,726 people
- Sponsor
- Sanofi
Cancer, Venous Thromboembolism
CANBESURE STUDY (Cancer, Bemiparin and Surgery Evaluation)
The aim of the study is to evaluate the efficacy and safety of Bemiparin, a second-generation LMWH, in the prophylaxis of VTE (using a postoperative regimen, i.e.
- Trial name
- NCT00219973
- Testing
- Bemiparin
- Where
- 4 sites in Portugal, Romania and 2 more
- Volunteers
- 526 people
- Sponsor
- Rovi Pharmaceuticals Laboratories
Prostate Cancer, Venous Thromboembolism
PREvention of VENous ThromboEmbolism Following Radical Prostatectomy
The PREVENTER Trial aims to compare the use of perioperative pharmacologic prophylaxis (subcutaneous heparin) with intermittent pneumatic compression devices (IPCs) to the use of IPCs alone for the prevention of venous…
- Conditions
- Prostate Cancer, Venous Thromboembolism, Lymphocele After Surgical Procedure, Deep Venous Thrombosis
- Trial name
- PREVENTER (NCT03006562)
- Testing
- Subcutaneous Heparin
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Johns Hopkins University
Deep Venous Thrombosis
D-Dimer Guided Oral Anticoagulant Treatment (OAT)
This clinical trial will investigate the hypothesis that D-Dimer testing can be successfully used to tailor the duration of OAT in patients after an unprovoked episode of deep venous thrombosis (DVT) using a prospective…
- Trial name
- DDOAT2006 (NCT00895505)
- Testing
- Phenprocoumon, Warfarin-Natrium
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bonn
Venous Thromboembolism
Prescription and Utilization of Low Molecular Weight Heparin in Usual Medical Practice for the Curative Treatment of Venous Thromboembolism in Patients With Cancer
The study purpose is to document the prescription and the use of Low Molecular Weight Heparin in usual medical practice in patients with cancer and established Venous Thromboembolism.
- Trial name
- NCT01803022
- Where
- France
- Volunteers
- 419 people
- Sponsor
- LEO Pharma
Deep Venous Thrombosis, Pulmonary Embolism
Risk Factors for Venous Thromboembolism
Deep venous thrombosis is the presence of blood clots, usually in the legs that lead to either local problems or breathing problems if the clot moves to the lungs.
- Trial name
- NCT00018772
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Deep Venous Thrombosis
Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies
The goal of the CRETE Studies is to investigate the newly identified age-dependent heterogeneity in the efficacy of enoxaparin in reducing the risk of central venous catheter-associated deep venous thrombosis in critically ill…
- Trial name
- CRETE (NCT04924322)
- Testing
- Enoxaparin
- Where
- 22 sites in United States
- Volunteers
- 258 people
- Sponsor
- Yale University
Cerebral Vein Thrombosis, Deep Vein Thrombosis
Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy
This randomized phase III trial studies the best dose of apixaban and how well it works in preventing secondary cancer related venous thrombosis in cancer patients who have completed anticoagulation therapy.
- Conditions
- Cerebral Vein Thrombosis, Deep Vein Thrombosis, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT03080883
- Testing
- Apixaban
- Where
- 32 sites in United States
- Volunteers
- 370 people
- Sponsor
- Academic and Community Cancer Research United
Venous Thromboembolism, Venous Thromboses
inDividual, Targeted thrombosIS Prophylaxis Versus the Standard 'One Size Fits All' Approach in Patients Undergoing Total hIp or Total kNee replaCemenT
After hip or knee replacement all patients receive a standardized treatment with blood thinners, this medication is called thrombosis prophylaxis.
- Conditions
- Venous Thromboembolism, Venous Thromboses, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- DISTINCT (NCT06581965)
- Testing
- Short duration prophylaxis, Higher intensity and longer duration prophylaxis, Control
- Where
- 13 sites in Netherlands
- Volunteers
- 10,078 people
- Sponsor
- Leiden University Medical Center
Thromboembolism, Arterial
Fiix-prothrombin Time for Monitoring Warfarin
Experiments suggest that during treatment with vitamin K antagonists (VKA) the activity of coagulation factors (F) II and X better reflect anticoagulation than does FVII.
- Conditions
- Thromboembolism, Arterial, Venous
- Trial name
- Fiix (NCT01565239)
- Testing
- Fiix prothrombin time
- Where
- Iceland
- Volunteers
- 1,156 people
- Sponsor
- Landspitali University Hospital
Venous Thromboembolism
Development and Validation of the Patient-completed Caprini Risk Score
The investigators aimed to test the reliability and validity of the Chinese version of patient-completed CRS in hospitalized patients and to evaluate whether this form can be widely used in clinical practice instead of only…
- Trial name
- NCT04663477
- Testing
- patient-completed Caprini Risk Score
- Where
- China
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Venous Thromboses, Colorectal Cancer
The Correlation of a D-dimer Testing Protocol With Venous Thromboembolism in Surgical Colorectal Patients
The purpose of this study is to evaluate the use of a D-dimer based protocol to screen for thrombotic events in colorectal surgical patients.
- Conditions
- Venous Thromboses, Colorectal Cancer, Diverticular Diseases, Crohn Disease
- Trial name
- NCT05246943
- Testing
- D-dimer and lower limb venous duplex
- Sponsor
- The University of Texas Medical Branch, Galveston
Dose Adjustment of Enoxaparin in ICU Patients
Anti-factor Xa Based Venous Thromboembolism Prophylaxis
Introduction: Venous thromboembolism (VTE) in the intensive care unit (ICU) is associated with significant morbidity and mortality therefore prevention is imperative to reduce its burden.
- Trial name
- NCT05221879
- Testing
- Dose adjustment of Enoxaparin in patients with sub-therapuetic (prophylactic) levels of factor 10a
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Meir Medical Center
Venous Thromboembolism, Cancer
Cancer Associated Thrombosis : What is the Proportion of Patients Ineligible to a Study as CARAVAGGIO
Venous thromboembolism is a common and fatal disease closely related to cancer. The therapeutic challenge is major due to the high risk of recurrent thromboembolism and bleeding in patients with cancer.
- Trial name
- NCT04846556
- Testing
- data collection
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Venous Thromboembolism, Major Bleed
Direct Oral Anticoagulants and Venous Thromboembolism
The purpose of this study is to determine whether use of direct oral anticoagulants (DOACs) is associated with an increased risk of major bleeding compared to warfarin use, for the treatment of venous thromboembolism (VTE).
- Trial name
- NCT02833987
- Testing
- Apixaban (ATC B01AF02), Dabigatran (ATC B01AE07), Rivaroxaban (ATC B01AF01)
- Where
- Canada
- Volunteers
- 59,525 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
Venous Thromboembolism
Venous thromboEmbolism Risk Profiles in Chinese hoSpitalized patiEnts (VERSE Study)
Venous thromboembolism (VTE) is a complex multifactorial disease, mainly manifested by deep vein thrombosis (DVT) and pulmonary embolism (PE).
- Trial name
- NCT05058521
- Where
- China
- Volunteers
- 27,490 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Venous Thromboembolism, Deep Venous Thrombosis
Rate of Venous Thrombosis in Acutely Ill Patients Hospitalized in Internal Medicine Wards
After reports from observational studies suggesting an association between acutely ill medical patients and venous thromboembolism (VTE), interventional trials with anticoagulants drugs have demonstrated a significant reduction…
- Trial name
- AURELIO (NCT03157843)
- Testing
- low-molecular-weight heparin
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- University of Roma La Sapienza
Deep Vein Thrombosis, Venous Thromboembolism
Single Session Percutaneous Mechanical Thrombectomy for the Treatment of Ilio-femoral Deep Vein Thrombosis: A Preliminary Evaluation
Venous thromboembolism (VTE) is a common condition that occurs when a clot develops in one of your veins. It affects 5% of the population and is the third most common circulatory condition after heart attack and stroke.
- Trial name
- SPADE (NCT02066597)
- Testing
- Thrombectomy
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Ottawa Hospital Research Institute