Clinical trials: Venous Thrombosis (Disorder)
Venous Thromboembolism
Incidence of Venous Thromboembolism and Professional Practices in Brest Area
The aim of this study estimate VTE incidence. Investigators prospectively record all cases of symptomatic pulmonary embolism (PE) and deep vein thrombosis (DVT) of the lower limbs diagnosed between March 1, 2013 and February 28…
- Trial name
- EPIGETBO III (NCT02895971)
- Where
- France
- Volunteers
- 1,416 people
- Sponsor
- University Hospital, Brest
Cardiovascular Diseases, Thromboembolism
Epidemiology of Venous Thromboembolism
To evaluate potentially modifiable lifestyle predictors of venous thromboembolism and their joint associations with biochemical and genetic determinants.
- Conditions
- Cardiovascular Diseases, Thromboembolism, Peripheral Vascular Diseases
- Trial name
- NCT00041457
- Sponsor
- Brigham and Women's Hospital
Acute Kidney Injury, Deep Venous Thrombosis
Norwegian Intensive Care Unit Dalteparin Effect Study
The main purpose of the NORIDES study is to investigate the effect of pharmacological thromboprophylaxis with low molecular weight heparins (LMWHs) in critically ill patients, and how it is affected by presence of acute kidney…
- Trial name
- NORIDES (NCT01721928)
- Testing
- Continuous venovenous hemodialysis
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Oslo University Hospital
Acute Lymphoblastic Leukemia
Hemostasis During Asparaginase Treatment in Acute Lymphoblastic Leukemia(ALL)
Asparaginase is an important drug in the treatment of childhood leukemia. One of the rare but severe side effects to the treatment is thrombosis in or outside the central nervous system.
- Trial name
- NCT01094392
- Where
- 4 sites in Denmark
- Volunteers
- 65 people
- Sponsor
- Aarhus University Hospital
Venous Thromboembolism
The Clinical Utility of Thrombelastography in Guiding Prophylaxis of Venous Thromboembolism Following Trauma
This study plans to learn more about how to prevent blood clots in the veins of your extremities. You are at risk of forming these clots after a major injury and when you have had surgery and are hospitalized on bed rest.
- Trial name
- VTEPX (NCT01050153)
- Testing
- Dalteparin sodium, Dalteparin sodium/aspirin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Denver Health and Hospital Authority
Portal Vein Thrombosis
Efficacy and Safety of Rivaroxaban in Acute Non-neoplastic Portal Vein Thrombosis in HCV
Portal vein thrombosis (PVT) in patients with liver cirrhosis may be due to neoplastic growth or non-neoplastic causes. Treating PVT with anticoagulation in liver cirrhosis is difficult to be established but may be of great…
- Trial name
- NCT03201367
- Testing
- Rivaroxaban, symptomatic therapy for ascites, abdominal pain
- Volunteers
- 40 people
- Sponsor
- Zagazig University
Diabetic Macular Edema, Macular Edema
Influence of Systemic Parameters in Diabetic Macular Edema - LIPSIA Study
This study aims to evaluate the influence and prognostic value of systemic factors (such as the cardiovascular and metabolic status) on the treatment response to anti-VEGF therapy in macular edema due to diabetes or retinal vein…
- Conditions
- Diabetic Macular Edema, Macular Edema, Retinal Vein Occlusion
- Trial name
- NCT03762226
- Testing
- Anti-VEGF
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Leipzig
Venous Thromboembolism
Title: Randomized Trial of an EHR Embedded Risk Calculator vs. Standard VTE Prophylaxis for Medical Patients
Venous thromboembolism (VTE) is a serious source of hospital morbidity and mortality. Chemoprophylaxis with heparin has been shown to reduce the occurrence of VTE, but it increases the risk of bleeding and it is uncomfortable to…
- Trial name
- NCT03243708
- Testing
- Risk calculator
- Where
- United States
- Volunteers
- 90,537 people
- Sponsor
- The Cleveland Clinic
Retinal Vein Occlusion
Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Retinal Vein Occlusion
Open-label, dose ascending safety, tolerability, and proof of concept study to evaluate the use of ANXV (human recombinant Annexin A5) in the treatment of subjects with recently diagnosed Retinal Vein Occlusion.
- Trial name
- NCT05532735
- Testing
- ANXV
- Where
- 7 sites in United States
- Volunteers
- 16 people
- Sponsor
- Annexin Pharmaceuticals AB
COVID-19, Critical Illness
Risk of Venous Thromboembolism in Critically Ill Patients With Severe COVID-19
Severe COVID-19 patients at a high risk of venous thromboembolism. We studied patients in 2 intensive care units of university hospitals in Barcelona and Badalona, Spain.
- Conditions
- COVID-19, Critical Illness, Venous Thromboembolism, Venous Thromboses
- Trial name
- NCT04374617
- Testing
- Duplex ultrasound and Computed Tomography Angiography
- Where
- 3 sites in Spain
- Volunteers
- 230 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Atrial Fibrillation, Venous Thromboembolism
NOACs Use in AF or VTE (SUNSHINE Registry)
The outcomes regiStry for non-vitamin k antagonist oral anticoagUlants treatmeNt in variouS tHrombotIc dIseases for better cliNical practicE (SUNSHINE) is a multicenter, prospective, observational non-interventional…
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Oral Anticoagulant
- Trial name
- NCT05378308
- Testing
- Patients with Atrial Fibrillation (AF) or venous thromboembolism (VTE)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Henan Provincial People's Hospital
Venous Obstruction
RECANA OUS - Recana Thrombectomy Catheter System for Venous Obstruction and Occlusion Study (RECANA-OUS-UK)
The goal of this clinical investigation is to learn if the Recana Thrombectomy Catheter System can treat chronic venous obstruction and occlusion in participants with symptomatic post-thrombotic venous inflow/outflow obstruction.
- Trial name
- NCT07219758
- Testing
- Recana Thrombectomy Catheter System
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Intervene, Inc.
Hepatocellular Carcinoma, Portal Vein Tumor Thrombosis
Safety and Efficacy of Radiotherapy Plus Sintilimab for HCC With Portal Vein Tumor Thrombosis
The proposed study is an open-label, single-center, single arm phase 1b study to evaluate the safety and efficacy of radiotherapy plus sintilimab for HCC with PVTT.
- Trial name
- NCT04104074
- Testing
- Radiotherapy, Sintilimab
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Venous Thromboembolism
VTE Prophylaxis Guidelines in Hospitalized Elders
Guideline directed use of pharmacologic Venous thromboembolism (VTE) prophylaxis emphasizes mobility evaluation. Mobility is a key component of risk stratification.
- Trial name
- NCT03025100
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Duke University
Cardiovascular Complications, Hemorrhagic Disorders
Comparison of Accidents and Their Circumstances With Oral Anticoagulants
Differences in efficacy and safety between new oral anticoagulants (NOAC) and vitamin K antagonist (VKA) in real practice remain uncertain.
- Conditions
- Cardiovascular Complications, Hemorrhagic Disorders, Embolism and Thrombosis
- Trial name
- CACAO (NCT02376777)
- Testing
- Follow up
- Where
- 33 sites in France
- Volunteers
- 4,162 people
- Sponsor
- CNGE IRMG Association
Myeloproliferative Neoplasm (MPN), Essential Thrombocythemia (ET)
Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients
Myeloproliferative neoplasms (MPNs) are blood disorders that occur when the body makes too many white or red blood cells, or platelets.
- Conditions
- Myeloproliferative Neoplasm (MPN), Essential Thrombocythemia (ET), JAK2 Mutation, Polycythemia Vera (PV)
- Trial name
- AIRPORT-MPN (NCT04243122)
- Testing
- Apixaban 2.5 MG Oral Tablet [ELIQUIS], Aspirin 81 mg
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Ottawa Hospital Research Institute
Acute Coronary Syndrome, Venous Thrombosis
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)
This prospective cohort study will provide information about: Characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed standard of care for the first…
- Conditions
- Acute Coronary Syndrome, Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation
- Trial name
- NCT02468102
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Standard of care drugs
- Where
- Sweden
- Volunteers
- 99,999 people
- Sponsor
- Bayer
Lymphoma, Acute Lymphoblastic Leukemia
A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase
The purpose of this study is to compare the effect of a blood thinning drug called Apixaban versus no administration of a blood thinning drug, in preventing blood clots in children with leukemia or lymphoma.
- Trial name
- NCT02369653
- Testing
- Apixaban, No systemic anticoagulant prophylaxis
- Where
- 96 sites in United States, Australia and 10 more
- Volunteers
- 512 people
- Sponsor
- Bristol-Myers Squibb
Venous Thromboembolism
Safety and Pharmacokinetics Study of DU-176b Administered to Patients With Severe Renal Impairment Undergoing Orthopedic Surgery of The Lower Limbs
To assess the safety and pharmacokinetics of DU-176b administered to patients with severe renal impairment undergoing orthopedic surgery of the lower limbs, compared with DU-176b administered to patients with mild renal…
- Trial name
- NCT01857583
- Testing
- 15mg DU-176b, 30mg DU-176b, Fondaparinux
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Macular Edema
A Study to Evaluate an Updated Dexamethasone Intravitreal (Into the Eye) Applicator in Adult Participants With Macular Edema Due to Diseases of the Retina
The Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) Applicator is used to deliver an implant with medicine to the eye. AbbVie is updating the DEX PS DDS Applicator.
- Trial name
- NCT04976777
- Testing
- Updated DEX PS DDS Applicator, Approved DEX PS DDS Applicator, Dexamethasone
- Where
- 7 sites in United States
- Volunteers
- 54 people
- Sponsor
- AbbVie
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