Clinical trials: Venous Thrombosis (Disorder)
Venous Thromboses, Venous Disease
The GORE® VIABAHN® FORTEGRA Venous Stent Iliofemoral Study
This study is a prospective, non-randomized, multicenter, single-arm, clinical study to evaluate the performance, safety and efficacy of the GORE® VIABAHN® FORTEGRA Venous Stent (formerly known as GORE® VIAFORT Vascular Stent)…
- Conditions
- Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
- Trial name
- NCT05489588
- Testing
- GORE® VIAFORT Vascular Stent
- Where
- 24 sites in United States
- Volunteers
- 165 people
- Sponsor
- W.L.Gore & Associates
Antithrombin Deficiency, Congenital
Assess Incidence of Deep Vein Thrombosis(DVT)Following Administration of Recombinant Human Antithrombin (rhAT) to Hereditary Antithrombin(AT) Deficient Patients in High Risk Situations.
Patients with hereditary antithrombin (AT) deficiency are at increased risk of venous thrombosis and pulmonary embolism, particularly during certain high risk procedures.
- Trial name
- rhAT (NCT00056550)
- Testing
- Recombinant Human Antithrombin (rhAT)
- Where
- 11 sites in United States, France and 4 more
- Volunteers
- 14 people
- Sponsor
- rEVO Biologics
Venous Stasis, Deep Venous Thrombosis
Comparison of the Effects of Lower Limb Immobilisation With Cast and Orthosis
In this study we are going to measure the blood flow in the lower limbs under cast immobilisation and also under mobilisation with an orthosis.
- Trial name
- NCT03420664
- Testing
- Orthosis VACOped, Below knee cast
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Deep Venous Thrombosis, Colonic Cancer
Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in Colorectal Cancer
The chemoprophylaxis of deep vein thrombosis (DVT) with subcutaneous low-molecular-weight heparin (enoxaparin) in the postoperative period of elective surgeries is already well established in the literature and in clinical…
- Trial name
- Ésquilo (NCT05303818)
- Testing
- Rivaroxaban 10 MG
- Where
- Brazil
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Hospital do Servidor Publico Estadual
Deep Vein Thrombosis, Total Hip Prosthesis
Generation of Thrombin and Prediction of Deep Vein Thrombosis Post Prosthetic Orthopedic Surgery of the Lower Limbs
The numerical ratio between the value of the thrombin generation test performed without soluble thrombomodulin and the value of the thrombin generation test performed in the presence of soluble thrombomodulin, performed…
- Conditions
- Deep Vein Thrombosis, Total Hip Prosthesis, Knee Prosthesis
- Trial name
- GT-PT (NCT03634124)
- Testing
- Blood test, Doppler ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Venous Thromboembolism, Ovarian Neoplasms
Venous Thromboembolic Complications in Ovarian Cancer
Objectives of the study are: To estimate the incidence of venous thromboembolism (VTE) in a cohort of women with suspected ovarian cancer and evaluate changes in the coagulation system in case of benign or malignant disease.
- Conditions
- Venous Thromboembolism, Ovarian Neoplasms, Ovarian Cancer, Deep Vein Thrombosis
- Trial name
- NCT02480790
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Ole Thorlacius-Ussing, MD, DMSc, Professor of Surgery
Age- Related Macular Degeneration, Diabetic Retinopathy
A Case-Control Study Revealing Intraocular Microenvironment Characteristics in Patients With Ocular Diseases Based on Multi-Omics Analysis
This project systematically investigates the role of the intraocular microbiome in various ocular diseases, including age-related macular degeneration, diabetic retinopathy, and cataracts.
- Conditions
- Age- Related Macular Degeneration, Diabetic Retinopathy, Retinal Vein Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT07897513
- Testing
- Not applicable- observational study
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Macular Edema, Retinal Vein Occlusion
A Safety and Efficacy Study of OZURDEX® in Macular Edema Associated With Branch Retinal Vein Occlusion
This study will evaluate the safety and efficacy of OZURDEX® (700 µg dexamethasone implant) in patients with macular edema associated with branch retinal vein occlusion.
- Trial name
- COBALT (NCT01903720)
- Testing
- dexamethasone implant
- Where
- South Korea
- Volunteers
- 71 people
- Sponsor
- Allergan
Venous Thromboembolism, Pulmonary Thromboembolisms
Time of Treatment With LMWH in Cancer Patients With Thromboembolic Disease
Cancer is the most important acquired risk factor of thromboembolisms. More than 20% of all episodes of venous thromboembolism (VT) or pulmonary thromboembolisms (PT) are cancer related.
- Conditions
- Venous Thromboembolism, Pulmonary Thromboembolisms, Cancer
- Trial name
- NCT03134820
- Volunteers
- 352 people
- Sponsor
- Delos Clinical
DVT - Deep Vein Thrombosis
Predictive Value of Modified Caprini Score and D-Dimer in Managing Lower Limb Venous Thrombosis in Cardiothoracic Patients
The goal of this observational study is to evaluate the predictive efficacy of the Modified Caprini Risk Assessment Score and D-Dimer in identifying and managing lower extremity venous thrombosis (LEVT) among cardiothoracic…
- Trial name
- DVT (NCT06729021)
- Testing
- GCS, LMWH
- Where
- Iraq
- Volunteers
- 112 people
- Sponsor
- Al-Nahrain University
Deep Vein Thrombosis, Deep Vein Thrombosis, Pulmonary Embolus
Determining the Validity of ThinkSono Guidance for Ultrasound Image Acquisition and Remote Detection
The purpose of this study is to confirm the safety and efficacy of ThinkSono Guidance, a software data collection and communication tool designed to collect ultrasound data to help detect blood clots in veins.
- Trial name
- DVT GUARD (NCT06652568)
- Testing
- ThinkSono System
- Where
- 5 sites in United States
- Volunteers
- 634 people
- Sponsor
- ThinkSono, Ltd.
Venous Thromboembolism, Deep Venous Thrombosis
A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE
This is a Phase 3,multicenter, randomized, open-label, blinded endpoint evaluation study comparing the effect of abelacimab relative to apixaban on venous thromboembolism (VTE) recurrence and bleeding in patients with cancer…
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism
- Trial name
- ASTER (NCT05171049)
- Testing
- Abelacimab, Apixaban
- Where
- 209 sites in United States, Australia and 19 more
- Volunteers
- 1,150 people
- Sponsor
- Anthos Therapeutics, Inc.
Age-Related Macular Degeneration, Diabetic Retinopathy
National Eye Institute Biorepository for Retinal Diseases
Background: To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time.
- Conditions
- Age-Related Macular Degeneration, Diabetic Retinopathy, Von Hippel-Lindau Syndrome, Retinal Disease
- Trial name
- NCT01496625
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Atrial Fibrillation, Deep Venous Thrombosis
Modeling Genotype and Other Factors to Enhance the Safety of Coumadin Prescribing
The study goal is to conduct a randomized controlled trial to compare safety and accuracy of dosing based on clinical information including the clinical reason for your taking coumadin, your age, gender, your body surface area…
- Conditions
- Atrial Fibrillation, Deep Venous Thrombosis, Heart Valve Replacement, Pulmonary Embolism
- Trial name
- NCT00484640
- Testing
- Coumadin
- Where
- 2 sites in United States
- Volunteers
- 260 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Deep Venous Thrombosis, Pulmonary Embolism
The DARE Warfarin CER Study
Approximately half a million Americans annually experience venous thromboembolic disease, including deep venous thrombosis (DVT) and pulmonary embolism (PE).
- Trial name
- NCT03271450
- Testing
- Dabigatran: extended treatment (e.g at least 90 days), Dabigatran: extended treatment (e.g at least 180 days), Dabigatran: extended treatment (e.g at least 270 days)
- Where
- United States
- Volunteers
- 416,000 people
- Sponsor
- Brigham and Women's Hospital
Central Venous Catheter Thrombosis
Thrombotic Complications After Central Venous Catheterization
Rationale: Complications related to central venous catheterization are mechanical, infectious or thrombotic in origin. Potential complications of catheter-related thrombosis are not insubstantial and include pulmonary embolism…
- Trial name
- TARZAN (NCT04302376)
- Testing
- Cather-related thrombosis ultrasonography
- Where
- Netherlands
- Volunteers
- 173 people
- Sponsor
- Amsterdam UMC, location VUmc
Deep Vein Thrombosis, Pulmonary Embolism
Exercise Intolerance and Skeletal Muscle Bioenergetics in Children With Deep Venous Thrombosis
This is a prospective cohort study of 30 patients who are 8-21 years of age with venous thromboembolism (VTE)- either lower extremity deep venous thrombosis (DVT) or pulmonary embolism (PE).
- Trial name
- NCT04294849
- Testing
- Magnetic Resonance Imaging, Bicycle Ergometry, Lab Panel
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Texas Southwestern Medical Center
Myeloproliferative Neoplasm, Splanchnic Vein Thrombosis
Outcomes in Patients With Myeloproliferative Neoplasm and Splanchnic Vein Thrombosis
Patients with Myeloproliferative neoplasms are at particular risk for developing arterial and venous thrombosis, especially thrombosis in the splanchnic venous system.
- Conditions
- Myeloproliferative Neoplasm, Splanchnic Vein Thrombosis, Splanchnic Venous Thrombosis, Myeloproliferative Disorders
- Trial name
- Mascot (NCT04631458)
- Testing
- standard of care.
- Volunteers
- 40 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Budd-Chiari Syndrome
Budd-Chiari Syndrome in China: Balloon Angioplasty Alone or Combined With Stent Placement?
Budd-Chiari syndrome (BCS) is defined as the hepatic outflow obstruction from the small hepatic veins to the confluence between inferior vena cava and right atrium, which often leads to the life-threatening complications, such as…
- Trial name
- NCT02201485
- Testing
- Stent, Balloon
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Central Venous Catheters, Central Venous Catheter Thrombosis
Catheter Associated Asymptomatic Thrombosis in Intensive Care Unit
This study aims to describe the incidence of catheter-related and non-catheter-related thrombosis in a population of adults in ICU and to assess its correlation with alteration of coagulation parameters.
- Conditions
- Central Venous Catheters, Central Venous Catheter Thrombosis, Thrombosis, Venous, Intensive Care Unit
- Trial name
- CAAT (NCT04503135)
- Testing
- ultrasound
- Where
- Italy
- Volunteers
- 203 people
- Sponsor
- Policlinico Hospital
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