Clinical trials: Ventilator Acquired Pneumonia
Respiratory Failure
Occurrence of Ventilator Associated Pneumonia in Italian ICU Using Cuffed Tracheostomy Tubes With Subglottic Secretion Drainage
Ventilator-associated pneumonia (VAP) is a serious complication and carries increased risks of morbidity and mortality for patients who require mechanical ventilation.
- Trial name
- VICTOR (NCT02223988)
- Testing
- subglottic secretion removal
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Turin, Italy
Neonatal SEPSIS, Nosocomially Acquired Neonatal Sepsis
A Study on Ventilator-associated Pneumonia as a Risk for Nosocomial Infection in Mechanically Ventilated Neonates In NICU of Assiut University Children Hospital (Nicu Eta)
Abstract Background: Neonatal ventilator associated pneumonia (VAP) is a major hospital-acquired infection in acute care settings, associated with high mortality and poor outcome.
- Trial name
- nicu eta (NCT03310840)
- Testing
- others
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ventilator Associated Pneumonia
The Effect of Colistin Inhalation on Ventilator Associated Pneumonia
The study has been conducted to measure the clinical outcome of early intervention with colistin inhalation in patients with ventilator associated pneumonia suspected to have multidrug resistant gram -ve bacteria
- Trial name
- NCT03622450
- Testing
- Colistin, Carbapenem + Aminoglycoside/ Quinolone
- Volunteers
- 40 people
- Sponsor
- Nourhan Hassan Osama Thuraya Mohamed
Ventilator Acquired Pneumonia
Assessment of the Role of Probiotics in Prevention of Ventilator-Associated Pneumonia in Neonates
Evaluate the preventive value of probiotics on VAP among ventilated neonates.
- Trial name
- NCT07001163
- Testing
- Probiotic
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Lamiaa Khaled Zidan
Ventilator Associated Pneumonia, Tracheobronchitis
Effect of Chlorhexidine-Induced Oral Care on Ventilator-Related Some Respiratory System Complications
Ventilator-associated pneumonia and ventilator-associated treakeabronchitis in respiratory tract infections associated with ventilator are common infections in intensive care unit and cause significant morbidity, mortality and…
- Trial name
- NCT04505202
- Testing
- 0.12% chlorhexidine gluconate
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Ventilator Associated Pneumonia (VAP)
Serial, Non-invasive Analysis of Exhaled Breath Condensate in Ventilated Trauma Patients
To determine if the analysis of exhaled breath condensate correlates with the development \& resolution of pneumonia.
- Trial name
- NCT02652247
- Testing
- molecular analysis of exhaled breath condensate, molecular analysis of mini-bronchoalveolar lavage (BAL) aspirate, molecular analysis of bronchoalveolar lavage (BAL) aspirate
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Vanderbilt University Medical Center
Pneumonia, Ventilator-Associated
Effect of Additional Nebulized Amikacin in Ventilator-Associated Pneumonia Caused by Gram Negative Bacteria
The purpose of this study is to determine the cure rate from ventilator-associated pneumonia (VAP) caused by Gram negative bacteria when administering add on nebulized amikacin to intravenous antibiotics compared to intravenous…
- Trial name
- NCT02574130
- Testing
- Amikacin
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Thammasat University
Wounds and Injuries, Respiratory Failure
Prehospital Ventilator-Associated Pneumonia Prevention Trial
Traumatic injury in rural America is a significant cause of morbidity and mortality, and the challenges of a rural trauma system can put patients at unique risk.
- Conditions
- Wounds and Injuries, Respiratory Failure, Pneumonia, Ventilator-Associated
- Trial name
- P-VAPP (NCT01902446)
- Testing
- Chlorhexidine gluconate
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Nicholas M Mohr
Ventilator-Associated Pneumonia, Tracheobronchitis
CT Scan and Lung Ultrasonography to Improve Diagnostic of Ventilation Acquired Pneumonia in ICU
We aim to show that systematic ultrasonography performed in ventilated patients suspected of ventilation-acquired pneumonia could improve the accuracy of diagnostic of pneumonia, and helps defining the diagnostic of…
- Trial name
- ECTOPICUS (NCT03018431)
- Testing
- CT Scan
- Where
- 2 sites in France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Ventilator Associated Pneumonia
PREdiction of CEphalosporinase Producing Enterobacteria During Ventilator-associated Pneumonia for Therapeutic Stewardship
Ventilator-associated pneumonia is the leading cause of nosocomial infection in the ICU. Cephalosporinase-producing Enterobacteriaceae have an increasing incidence.
- Trial name
- NCT05486130
- Where
- France
- Volunteers
- 345 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Infection, Bacteremia
Pharmacodynamic Parameters of Two Different Doses of Cefepime
Pharmacokinetics is the study of the disposition of drugs in the body, while pharmacodynamics considers the interaction of the drug at the site of infection over time.
- Conditions
- Infection, Bacteremia, Pneumonia
- Trial name
- NCT00177736
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Pittsburgh
Tracheostomy, Endotracheal Tube
Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients.
Artificial airways, such as endotracheal tubes and tracheostomies, in the pediatric and neonatal intensive care units (PICU, NICU respectively) are lifesaving for patients in respiratory failure, among other conditions.
- Conditions
- Tracheostomy, Endotracheal Tube, Ventilator Associated Pneumonia, Tracheitis
- Trial name
- NCT06201130
- Testing
- Suctioning of artificial airway
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwell Health
Pneumonia, Ventilator-Associated
Bilateral Bronchoalveolar Lavage in Ventilator-associated Pneumonia
The purpose of this study is to assess microbiologic concordance rates between right- and left-lung bronchoalveolar lavage cultures from patients with suspected ventilator-associated pneumonia, identify predictors of concordance…
- Trial name
- NCT02542553
- Testing
- Bilateral BAL
- Volunteers
- 79 people
- Sponsor
- Catholic University of the Sacred Heart
Pneumonia
A Peri-intubation Oral Intervention to Reduce Oral Flora and VAP
The purpose of this study is determine if a single, early dose of chlorhexidine applied within 12 hours after endotracheal tube insertion will reduce the bacteria in the oral cavity and the incidence of pneumonia in trauma…
- Trial name
- NCT00248300
- Testing
- Chlorhexidine
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Virginia Commonwealth University
Ventilator Acquired Pneumonia, Catheter Related Bloodstream Infection
Effect of Use of Probiotics on Systemic Infection in Critically Ill Patients: a Double Blind, Randomized, Placebo-controlled Trial
The primary goal of this study is to assess the benefit of probiotics in preventing or minimizing of various type of systemic infection in critically ill adult patients.
- Conditions
- Ventilator Acquired Pneumonia, Catheter Related Bloodstream Infection, Urinary Tract Infection, Diarrhea
- Trial name
- NCT07164781
- Testing
- Bacillus clausii, Sugar tablets
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Nosocomial Pneumonia
International Study on NoSocomial Pneumonia in Intensive CaRE (PneumoINSPIRE)
The International study on NoSocomial Pneumonia in Intensive CaRE (PneumoINSPIRE) is a prospective, international, multicentre, observational, cohort study.
- Trial name
- PneumoINSPIRE (NCT02793141)
- Testing
- No intervention
- Where
- 2 sites in Australia, Greece
- Volunteers
- 1,657 people
- Sponsor
- The University of Queensland
Pneumonia
Oral Care Protocol for Preventing Ventilator- Associated Pneumonia
The Nosocomial Pneumonia remains to be a major complication for patients who were incubated with ventilation. Most cases are attributed to increased bacteria flora in oropharyngeal secretion and aspiration of those organisms.
- Trial name
- VAP (NCT00604916)
- Testing
- standardized oral care protocol - electronic toothbrush, mimic protocol
- Volunteers
- 53 people
- Sponsor
- Mackay Memorial Hospital
Oral Infection, Ventilator-associated Pneumonia
Evaluating the Effectiveness of the Tongue Cleaner in Critical Patients
The concern with oral infection and its systemic repercussions is old, many studies have been undertaken to establish this relationship more precisely.
- Trial name
- NCT01294943
- Testing
- Tongue cleaner
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Ventilator Associated Pneumonia
The Diagnostic and Prognostic Utility of Procalcitonin (ProCT) for Ventilator-associated Pneumonia (VAP)
Our aim in this study is to investigate the potential role of serum ProCT as an early diagnostic marker and later prognostic indicator for VAP.
- Trial name
- NCT00498121
- Testing
- PROCALCITONIN LEVEL
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pneumonia, Ventilator-Associated
Immunity Markers in Intensive Care Patients and Ventilator-associated Pneumonia
The goal of this observational study is to show the direct correlation between the occurrence of recurrence of VAP and postagressive immunoparalysis, monitored by HLA-DR rate below litterature-acknowledged threshold, in a well…
- Trial name
- IMMUNAIX (NCT06607055)
- Testing
- Blood collection
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Intercommunal Aix-Pertuis