Clinical trials: Ventral Hernia
Hernia, Ventral, Hernia, Abdominal
Abdominal Wall Tension in Patients Undergoing Ventral Hernia Repair Without Component Separation
The purpose of this study is to use a scale to learn more about the tension of the abdominal wall in hernia repairs without component separation. 1.
- Conditions
- Hernia, Ventral, Hernia, Abdominal, Hernia Abdominal Wall
- Trial name
- NCT06051578
- Testing
- Abdominal wall tension measurement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Hernia, Ventral, Hernia, Hiatal
GORE® ENFORM Biomaterial Product Study
A prospective, retrospective, non-randomized, multicenter study with two independent hernia study cohorts (Ventral / Incisional Hernia Repair and Diaphragmatic / Hiatal Hernia Repair).
- Conditions
- Hernia, Ventral, Hernia, Hiatal, Hernia, Diaphragmatic, Incisional Hernia
- Trial name
- ENF 18-06 (NCT04718168)
- Testing
- Gore ENFORM Biomaterial (Preperitoneal), Gore ENFORM Biomaterial (Intraperitoneal)
- Where
- 9 sites in United States
- Volunteers
- 245 people
- Sponsor
- W.L.Gore & Associates
Ventral Hernia, Incisional Hernia
oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias
This study investigates on the effect of two different operative techniques to treat large abdominal wall defects. The goal of this clinical trial is to learn if the minimally-invasive, robotically-assisted ventral hernia repair…
- Conditions
- Ventral Hernia, Incisional Hernia, Abdominal Wall Defect
- Trial name
- PRIOR (NCT06364306)
- Testing
- Robotically-assisted ventral hernia repair (RVHR), Open ventral hernia repair (OVHR)
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 140 people
- Sponsor
- University Hospital, Basel, Switzerland
Ventral Hernia, Abdominal Wall Defect
ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair
This study investigates on the effect of two different operative techniques to treat abdominal wall hernias. The goal of this clinical trial is to learn if the eTEP (Extended totally extraperitoneal repair) technique leads to a…
- Trial name
- ALPINE (NCT06367309)
- Testing
- Extended totally extraperitoneal repair, Intraperitoneal onlay mesh
- Where
- Switzerland
- Volunteers
- 138 people
- Sponsor
- University Hospital, Basel, Switzerland
Hernia, Inguinal, Hernia, Femoral
Recover@Home Postoperative Follow-up Study
This proposal describes a human subjects research study evaluating mHealth Ambulatory Surgery with Follow-up Nurse (Recovery@Home), as an alternative postoperative care pathway for selected low-acuity surgical procedures in…
- Conditions
- Hernia, Inguinal, Hernia, Femoral, Hernia, Umbilical, Hernia, Ventral
- Trial name
- NCT07714343
- Testing
- Recovery@home
- Where
- 4 sites in Uganda
- Volunteers
- 194 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hernia, Hernia, Ventral
Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia
The purpose of RECOVER is to evaluate the performance and safety of Transorb™ self-gripping resorbable mesh in high-risk subjects (at least one risk factor impairing wound healing) when used for reinforcement of abdominal wall…
- Conditions
- Hernia, Hernia, Ventral, Hernia, Abdominal, Hernia Abdominal Wall
- Trial name
- RECOVER (NCT06449378)
- Testing
- Transorb™ Self-Gripping Resorbable Mesh
- Where
- 13 sites in United States, Belgium and 1 more
- Volunteers
- 163 people
- Sponsor
- Medtronic - MITG
Ventral Hernia, Inguinal Hernia
Methocarbamol in Ventral and Inguinal HR
The purpose of this study is to gather information on methocarbamol as a pain management treatment for ventral or inguinal hernia repair.
- Trial name
- NCT05388929
- Testing
- Methocarbamol, Standard Opioid, Standard opioid plus methocarbamol
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Prisma Health-Upstate
Hernia Incisional Ventral
LIQUIBAND FIX8® for Ventral Incisional Hernia
This study is designed to evaluate the safety and performance of device LiquiBand FIX8 Open hernia mesh fixation device. The use of this device is not experimental, as it is already approved for use in the EU (CE-marked).
- Trial name
- LBF8-03 (NCT07295379)
- Testing
- LIQUIBAND FIX8
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- Advanced Medical Solutions Ltd.
Ventral Hernia
CYP2D6 Genotype-guided Management of Opioid Analgesics in Patients Undergoing Elective Ventral Hernia Repairs
Pilot pragmatic trial using an implementation science approach to determine the feasibility of a CYP2D6-guided opioid prescribing for patients undergoing elective VHRs compared to usual care.
- Trial name
- NCT06565546
- Testing
- Opioid pain medication prescribed based on CYP2D6 genotype testing PLUS Acetaminophen and Gabapentin, Acetaminophen and Gabapentin: standard postoperative pain medications
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Ventral Incisional Hernia
Shear-Wave Elastography
Prospective cohort study of patients with midline ventral incisional hernia with a range of hernia morphology who plan to undergo open retromuscular VHR.
- Trial name
- ELASTOGRAPHY (NCT06306976)
- Testing
- Elective Midline Laparotomy, Imaging: Ultrasound, Tensiometry
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Ventral Hernia Repair
Effect of Pressure Biofeedback Training After Ventral Hernioplasty
The goal of this clinical trial is to evaluate the effect of pressure biofeedback training on abdominal muscle strength and quality of life in adults following ventral hernioplasty.
- Trial name
- NCT07642219
- Testing
- pressure biofeedback training, conventional physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Ventral Hernia Repair, Opioid Consumption, Postoperative
Opioid Education Ventral Hernia Repair
The goal of this study is to learn if opioid education before surgery affects prescribed opioid use after surgery in participants who are undergoing a ventral hernia repair.
- Trial name
- NCT07639281
- Testing
- Opioid and Surgery Education Video, Surgery Education Video
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Tori Dotson
Ventral Hernia, Hernia
Pilot Trial of Abdominal Core Rehabilitation To Improve Outcomes After Ventral Hernia Repair
This study aims to evaluate the potential role of physical therapy in improving outcomes after ventral hernia repair.
- Conditions
- Ventral Hernia, Hernia, Herniorrhaphy, Abdominal Wall
- Trial name
- ABVENTURE-P (NCT05142618)
- Testing
- Supervised Physical Therapy, Post-operative Precautions
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Ohio State University
Frailty, Ventral Hernia
Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair
The purpose of this study is to assess the physical fitness of patients undergoing hernia repair and correlate the postoperative outcomes and recovery as well as assess the impact of a targeted physical exercise program…
- Trial name
- NCT06874413
- Testing
- Prehabilitation, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Prisma Health-Upstate
Ventral Hernia
A Multicenter Belgian Trial of Ventral Hernia Repair (UNITE)
Patients with incisional midline ventral hernias with a minimal width of 3 cm and a maximal width of 8 cm, treated according to the standard practice of the participating investigators.
- Trial name
- RB-UNITE-01 (NCT04437043)
- Testing
- quality of life questionnaires
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Abdominal Hernia
Open Versus Robotic-assisted Ventral Hernia Repair, Short and Long-term Outcome
In this randomized clinical trial, the investigators will compare the conventional open repair for hernia in the anterior abdominal wall with the robotic-assisted approach.
- Trial name
- NCT05906017
- Testing
- Open Hernia surgery, Robotic Hernia surgery
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- University of Southern Denmark
Hernia, Ventral, Hernia, Inguinal
Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh
This study is designed to evaluate the post-operative complications and hernia recurrence following the use of OviTex in subjects with ventral or inguinal hernias.
- Trial name
- BRAVOII (NCT04779918)
- Testing
- OviTex Reinforced Tissue Matrix
- Where
- 10 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Tela Bio Inc
Inguinal Hernia, Ventral Hernia
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Hernia Surgery (Enable Hernia Repair)
A prospective, multicenter, single-arm pivotal study will be performed with 192 subjects enrolled to have an inguinal or ventral robotic hernia repair procedure using the Medtronic Hugo™ RAS system.
- Trial name
- NCT06445504
- Testing
- Robotic-Assisted Surgery (RAS) Hernia Repair Surgery
- Where
- 7 sites in United States
- Volunteers
- 206 people
- Sponsor
- Medtronic - MITG
Ventral Hernia Midline, Hernia Lumbar
Prospective Study of Minimally Invasive (Laparoscopic and Robotic) Hernia Repair (Incisional and Primary, Midline and Lateral, Not Inguinal)
The participating researchers register all adult patients (who have given informed written consent) scheduled for elective repair of an abdominal wall hernia (NOT inguinal hernias) via minimally invasive operation technique…
- Conditions
- Ventral Hernia Midline, Hernia Lumbar, Incisional Hernia Repair
- Trial name
- PROMISER (NCT07544238)
- Testing
- Minimally invasive hernioplastia
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Hernia, Ventral, Neuromuscular Blockade
Prospective Randomized Trial of Moderate vs Deep Neuromuscular Blockade During Laparoscopic Ventral Hernia Repair
The proposed study aims to assess the effect of different levels of muscle relaxation on the success of low-pressure insufflation, surgical conditions and patient recovery following laparoscopic repair of a ventral hernia (VHR)…
- Conditions
- Hernia, Ventral, Neuromuscular Blockade, Pneumoperitoneum
- Trial name
- NCT03201744
- Testing
- Patients will be randomized to moderate (TOF 1-2) or deep (post tetanic count 1-2) relaxation. Low pressure insufflation (start pressure set at 8 mm Hg)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stony Brook University