Clinical trials: Ventral Hernia Repair
Pain, Postoperative, Anesthesia, Local
Improving Pain Relief Following Laparoscopic Ventral Hernia Repair
Aim The general aim of this study is to improve post-operative pain and reduce morphine consumption following laparoscopic ventral hernia repair (LVHR).
- Conditions
- Pain, Postoperative, Anesthesia, Local, Hernia, Ventral, Laparoscopy
- Trial name
- NCT02785276
- Testing
- AutoFuser Pain Pump, Ropivacaine, Normal Saline (0.9%)
- Where
- New Zealand
- Sponsor
- University of Auckland, New Zealand
Ventral Hernia
Investigating the Feasibility and Outcomes of Patient Self-Drain Removal After Ventral Hernia Repair
The goal of this randomized controlled trial is to teach patients to safely and effectively self-remove drains at home in adults (aged 18 and older) following a ventral hernia repair (VHR).
- Trial name
- SDR (NCT06237855)
- Testing
- Self-drain removal
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wake Forest University Health Sciences
Ventral Hernia, Umbilical Hernia
Case-control Study of Mesh-infection After a Size Tailored Hernia Repair With C-Qur V-Patch
Ventral hernias, such as umbilical, epigastric and trocar-site hernias, are best repaired with abdominal wall reinforcement by mesh implantation.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia, Trocar-site Hernia
- Trial name
- Re-SITUP (NCT01761708)
- Testing
- primary ventral hernia repair with mesh
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Ventral Hernia
Long-Term Follow-up After Ventral Hernia Repair With Strattice Mesh
This study will assess long-term outcomes (greater than 12 months) following ventral hernia repair with Strattice mesh reinforcement.
- Trial name
- NCT04853550
- Testing
- Strattice Mesh
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Louisville
Ventral Hernia, Postoperative Pain
Comparison of Two Plane Blocks Used in Open Ventral Hernia Repair Operations
The aim of this study is to compare the postoperative analgesic efficacy of bilateral erector spinae plane block and bilateral external oblique-intercostal plane block in patients undergoing open ventral hernia repair.
- Conditions
- Ventral Hernia, Postoperative Pain, Postoperative Nausea, Postoperative Vomiting
- Trial name
- NCT07163026
- Testing
- Erector Spine Plane Block, External Oblique - Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Hernia, Ventral
Effect of a Preoperative Pulsed Electromagnetic Field and Abdominal Exercises on Muscle Strength Post Ventral Hernioplasty
The aim of this study is to investigate the impact of a preoperative pulsed electromagnetic field and abdominal exercises on muscle strength post ventral hernioplasty.
- Trial name
- NCT05559190
- Testing
- Pulsed electromagnetic field, Graduated abdominal strengthening exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Ventral Hernia
Pain and Quality of Life After Retromuscular Ventral Hernia Repair (RECOVER)
The study aims to explore the difference in outcomes relating to pain and quality of life after open, laparoscopic, and robotic-assisted retromuscular ventral hernia repair.
- Trial name
- RECOVER (NCT04487522)
- Testing
- Open retromuscular ventral hernia repair, Laparoscopic retromuscular ventral hernia repair, Robotic-assisted retromuscular ventral hernia repair
- Where
- 4 sites in United States
- Volunteers
- 74 people
- Sponsor
- Intuitive Surgical
Hernia, Ventral, Pregnancy
Pregnancy Subsequent to Ventral Hernia Repair
We will examine the outcome of ventral hernia repair with subsequent pregnancy
- Trial name
- NCT02398565
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 7,612 people
- Sponsor
- Bispebjerg Hospital
Pain, Postoperative, Opioid Use
Impact of Quadratus Lumborum Block on Recovery Profile After Ventral Hernia Repair
Ventral hernia repair may be associated with significant postoperative pain. Pain is typically managed with intravenous (IV) and oral medications that come with their own risks, such as nausea, constipation, sedation, respiratory…
- Trial name
- NCT03794882
- Testing
- Quadratus Lumborum Block, Standard Medical Management
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Incisional Hernia
Botulinum Toxin A Facilitates Fascial Closure in Complex Incisional Hernias
Brief Study Description This prospective observational study evaluates the use of preoperative botulinum toxin A as part of a structured clinical pathway for patients undergoing elective repair of complex midline incisional…
- Trial name
- BRIDGE-HERNIA (NCT07349628)
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Ventral Hernia
Gentrix® Surgical Matrix for Soft Tissue Reinforcement in Ventral Hernia Repair
The purpose of this study is to collect additional safety data and demonstrate the performance of Integra Gentrix® Surgical Matrix for reinforcement of ventral hernia repairs.
- Trial name
- NCT05610267
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Integra LifeSciences Corporation
Ventral Hernia
Ventral Mesh Hernioplasty : Laparoscopic Versus Open Sublay
To compare between laparoscopic ventral hernia repair and open sublay technique (recurrence ,operative time ,bleeding ,rate of complication and injury , seroma, post operative pain)
- Trial name
- NCT06149858
- Testing
- hernioplasty
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ventral Hernia
Comparative Study of Biologic Mesh Versus Repair With Component Separation.
The purpose of this study is to compare open abdominal incisional hernia repair using XenMATRIX biologic mesh versus repair with their own tissue.
- Trial name
- Davol (NCT01295125)
- Testing
- XenMATRIX mesh, Open abdominal ventral hernia repair
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Post Abdominal Surgery Pain
A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery
The study schedule is comprised of a 14-day Screening Period, a treatment period and an observation period. All eligible subjects will be randomized into one of 3 treatment groups (1 of 2 dose levels or matched placebo).
- Trial name
- NCT02542384
- Testing
- CR845 IV 1 mcg/kg, CR845 IV 0.5 mcg/kg
- Where
- 23 sites in United States
- Volunteers
- 451 people
- Sponsor
- Cara Therapeutics, Inc.
Ventral Hernia
A Multicenter Belgian Trial of Ventral Hernia Repair (UNITE)
Patients with incisional midline ventral hernias with a minimal width of 3 cm and a maximal width of 8 cm, treated according to the standard practice of the participating investigators.
- Trial name
- RB-UNITE-01 (NCT04437043)
- Testing
- quality of life questionnaires
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Ventral Hernias
Abdominal Binder to Reduce Pain and Seroma Formation
Postoperative seroma formation is one of the most common complications after ventral hernia repair. Although some seromas may not have clinical impact, postoperative seroma formation often causes pain and discomfort and may even…
- Trial name
- ABD- BINDER (NCT01673568)
- Testing
- ETO garments
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Hvidovre University Hospital
Ventral Hernia, Ventral Incisional Hernia
Open Preperitoneal Mesh Versus Retromuscular Mesh Versus Suture Repair for Abdominal Wall Hernias
Randomized clinical trial comparing open preperitoneal mesh, retromuscular mesh and suture repair for ventral hernias less than 3 cm diameter
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Umbilical Hernia
- Trial name
- NCT03255239
- Testing
- Ventral hernia repair
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital Universitaire Taher Sfar
Hernia
AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE
The primary purpose of this clinical trial is to assess the safety and performance of the ECLIPSIUM device in securing mesh during ventral hernia repair.
- Trial name
- UNITE (NCT07277946)
- Testing
- ECLIPSIUM® System, Resorbable tacks (AbsorbaTack/SorbaFix)
- Where
- 12 sites in United States
- Volunteers
- 240 people
- Sponsor
- Tissium
Ventral Hernia
Laparoscopic Ventral Hernia Repair by Heavy Weight or Lighter Weight Mesh (COMPOSIX-trial)
1. General antibiotic prophylaxis: cefazoline (Cefacidal™) 2 gram iv administered 30 minutes before surgery 2. Laparoscopic surgery at least 5 cm overlap (mesh diameter should exceed hernia size by at least 10 cm) with or without…
- Trial name
- NCT00573105
- Testing
- Laparoscopic Ventral hernia repair by heavy weight mesh, Laparoscopic Ventral hernia repair by lighter weight mesh
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- University Hospital, Ghent
Ventral/Incisional Hernia Repairs
Trunk Strength Study
The purpose of this study is to measure abdominal wall strength both preoperatively and postoperatively in patients undergoing ventral/incisional hernia repairs.
- Trial name
- NCT01300936
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Kentucky