Clinical trials: Ventricular Arrhythmia
Cardiac Arrest, Out-Of-Hospital, Ventricular Fibrillation
Utility and Procedural Feasibility of REBOA Operationalized for Non-Trauma Application (UP-FRONT)
Single center randomized-controlled trial in out-of-hospital cardiac arrest (OHCA) patients. This study will investigate the feasibility and utility of the Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)…
- Conditions
- Cardiac Arrest, Out-Of-Hospital, Ventricular Fibrillation, Ventricular Tachycardia
- Trial name
- UP-FRONT (NCT05236920)
- Testing
- Resuscitative Endovascular balloon occlusion of the aorta using a REBOA catheter device
- Sponsor
- University of Alabama at Birmingham
Tachycardia, Atrioventricular Nodal Reentry
AV Nodal Reentrant Tachycardia Study
The purpose of this study is to determine/identify what mechanisms/factors are involved with regard to AV nodal reentrant tachycardia.
- Trial name
- AVNRT (NCT00618683)
- Testing
- Cardiac Invasive Electrophysiological Study
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Oklahoma
Heart Failure, Tachycardia, Ventricular
Effects of Monopolar Electrocautery Use During Surgery on Implanted Cardiac Defibrillators
This observational protocol will evaluate the effects of monopolar electrocautery (ME) on implantable cardioverter defibrillators (ICDs) in patients undergoing surgery.
- Trial name
- NCT01572246
- Testing
- Optimal placement of return pad
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- Oregon Health and Science University
Ventricular Tachycardia, Ischemic Cardiomyopathy
Venous Ethanol for Ventricular Tachycardia
Comparative effectiveness randomized clinical trial, comparing endocardial radiofrequency ablation alone vs radiofrequency ablation combined with venous ethanol in patients with ischemic ventricular tachycardia -Venous Ethanol…
- Trial name
- VELVET (NCT05511246)
- Testing
- Venous ethanol, Catheter ablation
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- The Methodist Hospital Research Institute
Paroxysmal Supraventricular Tachycardia (PSVT)
The PSVT Place Registry.Paroxysmal Supraventricular Tachycardia (PSVT) Registry.
Paroxysmal supraventricular tachycardia (PSVT) is a sporadic, sudden, and recurring tachycardia that is caused by an altered electrical conductivity in the heart.
- Trial name
- NCT03353610
- Where
- United States
- Volunteers
- 354 people
- Sponsor
- Milestone Pharmaceuticals Inc.
Atrial Fibrillation, Atrial Flutter
The Z Stitch Early Bed Rest Assessment Study
The goal of this study is to understand the effects of early mobilization after a Z stitch procedure in patients undergoing certain heart-related treatments.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia, Syncope
- Trial name
- ZEBRA (NCT06087497)
- Testing
- Early mobilization
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
Heart Failure With Reduced Ejection Fraction
Improving CRT Outcome With Non-Invasive Cardiac Mapping
The ICONIC-M study is a multicenter randomized controlled study to assess patient response to CRT comparing ECGI map guided left ventricular lead placement with empirical lead placement.
- Trial name
- ICONIC-M (NCT05564793)
- Testing
- Pre-implantation planning, Post-implantation assessment
- Where
- 11 sites in Netherlands, Portugal and 2 more
- Volunteers
- 330 people
- Sponsor
- EP Solutions SA
Slow Arrhythmia, His Bundle Pacing
Effect of His Bundle Pacing in Treatment of Slow Arrhythmia on Function of Left Atrial and Ventricle in Short Term
Bradyarrhythmia is one of the common diseases. Also, bradyarrhythmia could result in syncope, clinic convulsion, shock, sudden death and so on, which could influence people's life quality severely.
- Conditions
- Slow Arrhythmia, His Bundle Pacing, Function of Left Atrial and Ventricle
- Trial name
- NCT03685617
- Testing
- Dual Chamber Pacemaker, His Bundle Pacemaker
- Where
- China
- Volunteers
- 84 people
- Sponsor
- The Second Hospital of Hebei Medical University
Atrial Fibrillation
Propagation ANalysis for Arrhythmogenic Conduction Elimination to Prevent Atrial Flutter and Fibrillation (PANACEA-AF)
The purpose of this study is to perform ultra-high density mapping of the left atrium (a chamber of the heart) using the the Rhythmia Mapping System and to determine whether additional ablation in areas of wavefront…
- Trial name
- PANACEA-AF (NCT03737838)
- Testing
- Atrial fibrillation ablation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Chicago
Bradycardia, Heart Block
Right Ventricular Lead Placement in a Pacemaker Population: Evaluation of Apical and Alternative Position
This study is a long-term, prospective, and controlled evaluation of the mechanical dyssynchrony induced by right ventricular apical pacing, both in acute (spontaneous and stimulated) and chronic (12 and 24 months); the study…
- Conditions
- Bradycardia, Heart Block, Sick Sinus Syndrome
- Trial name
- NCT01647490
- Testing
- Permanent Cardiac Pacemaker Implantation
- Where
- 2 sites in Italy
- Volunteers
- 408 people
- Sponsor
- Ospedale Santa Maria di Loreto Mare
Ventricular Premature Complexes
CBT for Premature Ventricular Contractions
The purpose of the present interdisciplinary research program is to develop and evaluate a disease-specific cognitive behavior therapy (CBT) protocol to increase quality of life (QoL) and reduce symptom burden in patients with…
- Trial name
- PVC-CBT (NCT05087238)
- Testing
- CBT
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Premature Ventricular Beats
Study to Reduce Symptoms of Premature Beats With Ranolazine
Investigate whether ranolazine, a novel anti-anginal agent with antiarrhythmic properties, has a role in the management of symptomatic ventricular premature beats.
- Trial name
- RSVP (NCT01996618)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Walter Reed National Military Medical Center
Hypertrophic Cardiomyopathy
A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy
The purpose of this research study is to understand more about various heart rhythms (electrical problems) in persons with hypertrophic cardiomyopathy with and without sleep apnea.
- Trial name
- NCT04112290
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Mayo Clinic
Arrhythmogenic Right Ventricular Cardiomyopathy
Pilot Randomized Trial With Flecainide in ARVC Patients
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inherited arrhythmia disorder with high risk of ventricular tachycardia or fibrillation, and implantable cardioverter defibrillator remains as therapy of choice.
- Trial name
- NCT03685149
- Testing
- Flecainide Pill
- Where
- 6 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Rochester
Sick Sinus Syndrome, Atrioventricular Nodal Dysfunction
Left Bundle Branch Versus Minimized Ventricular Pacing in Patients With Sick Sinus Syndrome and Prolonged AV Interval
The goal of this clinical trial is to compare two pacemaker strategies: Left Bundle Branch Area Pacing (LBBAP) and Minimized Ventricular Pacing (MVP) in patients requiring a permanent pacemaker for sick sinus syndrome and…
- Trial name
- CLOSE-AV (NCT07314008)
- Testing
- LBBAP, MVP
- Where
- South Korea
- Volunteers
- 440 people
- Sponsor
- Asan Medical Center
Arrhythmias, Cardiac, Atrial Fibrillation
Activation Timing and Atrial Fibrillation
This is a single center, non-randomized, unblinded study of patients who are followed at Essentia Health - St. Mary's Medical Center and who are referred for a clinically indicated diagnostic electrophysiology (EP) study with or…
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Bundle Branch Block
- Trial name
- AF-Activate (NCT02063191)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Essentia Health
Cardiovascular Diseases, Coronary Artery Disease
AI-Powered Electrocardiography for Diagnosis and Prognostic Prediction in Cardiovascular Disease (AI-CVD): Multicenter Retrospective Study
This multicenter retrospective study aims to develop, validate, and clinically apply an artificial intelligence (AI)-powered electrocardiography (ECG) algorithm for the diagnosis and prognostic prediction of cardiovascular…
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Failure, Atrial Fibrillation (AF)
- Trial name
- AI-CVD (NCT07856472)
- Testing
- Retrospective ECG Data Analysis
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Inha University Hospital
Mitral Valve Insufficiency, Atrial Fibrillation
Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation
A large left atrial (LA) volume, which represents chronic diastolic dysfunction, is associated with a poor outcome, regardless of systolic function.
- Conditions
- Mitral Valve Insufficiency, Atrial Fibrillation, Heart Failure
- Trial name
- NCT01172184
- Testing
- Cardiac catheterization
- Where
- Taiwan
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Left Ventricular Dysfunction, Ventricular Dysfunction
Low Ejection Fraction in Single Lead ECG
The purpose of this research is to prospectively test and validate the single-lead Low EF algorithm in outpatients in order to test the performance of a single-lead ECG based algorithm to identify people with decreased left…
- Conditions
- Left Ventricular Dysfunction, Ventricular Dysfunction, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT05010655
- Testing
- Use of Eko DUO Electronic Stethoscope
- Where
- 2 sites in United States
- Volunteers
- 1,935 people, healthy volunteers welcome
- Sponsor
- Eko Devices, Inc.
Premature Ventricular Complexes, Ventricular Arythmias
WHEN DO WE HAVE to PERFORM CARDIAC MAGNETIC RESONANCE in PATIENTS REFERRED for PREMATURE VENTRICULAR COMPLEXES by THEIR CARDIOLOGISTS
Premature ventricular complexes (PVC) are a common entity affecting approximatively 20% of the general population. It can be discovered incidentally on electrocardiogram (ECG) or associated with symptoms with a wide spectrum from…
- Conditions
- Premature Ventricular Complexes, Ventricular Arythmias, Cardiac Magnetic Resonance Imaging, Focal or Diffuse Fibrosis
- Trial name
- IRMESV (NCT06801743)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens