Clinical trials: Ventricular Arrythmia
Heart Failure, Implantable Defibrillator User
Global Electrical Heterogeneity and Clinical Outcomes
This retrospective multicenter cohort will validate an independent association of electrocardiographic (ECG) global electrical heterogeneity (GEH) measures with sustained ventricular tachyarrhythmias and appropriate ICD therapies…
- Conditions
- Heart Failure, Implantable Defibrillator User, Ventricular Arrythmia
- Trial name
- GEHCO (NCT03210883)
- Where
- 6 sites in United States
- Volunteers
- 3,471 people
- Sponsor
- Larisa Tereshchenko
Ventricular Fibrillation, Ventricular Arrythmia
Noninvasive Electrocardiographic Imaging for Individuals at Risk for Apparently Idiopathic Ventricular Fibrillation.
This study aims to evaluate the electrophysiological properties of the heart conduction system in patients with unexplained polymorphic ventricular tachycardia (VT) and/or ventricular fibrillation (VF), in patients with specific…
- Conditions
- Ventricular Fibrillation, Ventricular Arrythmia, Polymorphic Ventricular Tachycardia, Sudden Cardiac Death
- Trial name
- VIGILANCE (NCT03963271)
- Testing
- ECG-Imaging
- Where
- 3 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Maastricht University Medical Center
Cardiac Arrest, Ventricular Arrythmia
Prophylactic Amiodarone for Shockable Cardiac Arrest
The aim of this study is to determine whether the prophylactic amiodarone can prevent re-arrest with ventricular shockable rhythm in patients who treated with targeted temperature management after return of spontaneous…
- Trial name
- NCT04845607
- Testing
- Amiodarone Injection
- Where
- South Korea
- Volunteers
- 302 people
- Sponsor
- Won Young Kim
Sudden Cardiac Death, Cardiac Arrest
Experience From the Italian S-ICD Registry
The purpose of this registry is to collect data on implant parameters, early, mid and long-term clinical effectiveness of Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) therapies in order to better understand how to…
- Conditions
- Sudden Cardiac Death, Cardiac Arrest, Ventricular Arrythmia, Implantable Cardiac Defibrillator
- Trial name
- ELISIR (NCT04373876)
- Testing
- Subcutaneous Implantable Cardioverter Defibrillator
- Where
- 18 sites in France, Germany and 2 more
- Volunteers
- 500 people
- Sponsor
- Luigi Sacco University Hospital
Cardiac Arrhythmia, Atrial Fibrillation
Vektor vMap™ Clinical Validation Study
This is a retrospective, multi center clinical study collecting existing, de-identified subject data from medical records to be analyzed using an independent core laboratory to validate performance of a computational ECG mapping…
- Conditions
- Cardiac Arrhythmia, Atrial Fibrillation, Ventricular Arrythmia, Premature Ventricular Complexes Multiple
- Trial name
- NCT04559061
- Testing
- Cardiac ablation procedure
- Where
- 4 sites in United States
- Volunteers
- 225 people
- Sponsor
- Vektor Medical
Congenital Heart Disease, Fallot Tetralogy
Prospective Evaluation of Programmed Ventricular Stimulation Before Pulmonary Valve Replacement in Patients With Tetralogy of Fallot
Severe pulmonary regurgitation is common in patients with Tetralogy of Fallot and results in progressive right ventricular dilatation and dysfunction.
- Conditions
- Congenital Heart Disease, Fallot Tetralogy, Ventricular Arrythmia, Pulmonary Valve Regurgitation
- Trial name
- NCT04205461
- Testing
- Programmed ventricular stimulation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Paris Cardiovascular Research Center (Inserm U970)
Sudden Cardiac Arrest, Ventricular Arrythmia
Improve Sudden Cardiac Arrest Study
The purpose of this study is to demonstrate that primary prevention patients with one or more additional risk factors (1.5 prevention criteria: syncope/pre-syncope, non-sustained ventricular tachycardia (NSVT), frequent…
- Trial name
- NCT02099721
- Testing
- ICD or CRT-D Device
- Where
- 93 sites in Argentina, Belarus and 14 more
- Volunteers
- 4,222 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
COVID, Arrhythmia
COVIDAR - Arrhythmias in COVID-19
BACKGROUND AND RATIONALE: There is very limited literature available on the arrhythmia occurrence in the context of an infection by the SARS-CoV2 virus.
- Conditions
- COVID, Arrhythmia, Torsades de Pointe Caused by Drug, Qt Interval, Variation in
- Trial name
- COVIDAR (NCT04437901)
- Where
- 5 sites in Belgium, Italy and 3 more
- Volunteers
- 10,000 people
- Sponsor
- Hospital Clinic of Barcelona
Ventricular Arrythmia
Safety and Efficacy of Catheter Ablation of Idiopathic Ventricular Arrhythmias Arising From Cardiac Outflow Tracts
Ventricular arrhythmias arising from cardiac outflow tract affect quality of life and can cause decrease in left ventricular ejection fraction. Drugs used for treating those arrhytmias may be ineffective or may have side effects.
- Trial name
- NCT03258112
- Testing
- Radiofrequency cardiac catheter ablation
- Sponsor
- Assiut University
Diabetes Mellitus, Heart Failure
Sodium-glucose Co-transporter 2 Inhibitors Effects in Failing Heart Patients
SLGT2 therapy is safety used in heart failure (HF) patients with depressed left ventricle ejection fraction (LVEF) and diabetes mellitus (DM).
- Conditions
- Diabetes Mellitus, Heart Failure, Ventricular Arrythmia
- Trial name
- NCT03977116
- Testing
- SLGT2
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Campania Luigi Vanvitelli
Arrhythmia, Atrial Fibrillation
Esophageal 3D Mapping System for Cardiac Arrhythmias
The aim of the study is to develop and validate a novel esophageal mapping system to improve the diagnostics of cardiac arrhythmias.
- Conditions
- Arrhythmia, Atrial Fibrillation, Atrial Flutter, Atrial Tachycardia
- Trial name
- esoECG-3D (NCT03365440)
- Testing
- esoECG-3D catheter
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ventricular Arrythmia, Infarction, Myocardial
A Novel Myocardial Impedance Mapping System for Ablation of Post-infarction Ventricular Arrhytmias in Humans
Precise identification of the infarct scar is essential for successful catheter ablation of ventricular arrhythmias in patients with chronic myocardial infarction.
- Trial name
- NCT04000412
- Testing
- CardioZ multifrequency impedance recording system
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Ventricular Arrythmia, Lead
Safety and Electrical Performance Evaluation of INVICTA Leads Models Equipped With DF4 Connector
The primary objective of this study is to assess the safety and key electrical performance of the INVICTA leads equipped with DF4 connector: ACTIVE fixation type models (single and dual coil: INVICTA 1CR, INVICTA 2CR) and PASSIVE…
- Conditions
- Ventricular Arrythmia, Lead, ICD, Heart Failure
- Trial name
- FRIENDS (NCT03766919)
- Testing
- Implant of the INVICTA lead
- Where
- 10 sites in France, Italy and 2 more
- Volunteers
- 33 people
- Sponsor
- MicroPort CRM
Ventricular Tachycardia, Arrythmia
Rook Epicardial Access Device Study
The purpose of this study is to confirm the efficacy and safety of the Talon Surgical Rook® Epicardial Access Kit as a pericardial access device.
- Trial name
- NCT03427333
- Testing
- The Rook® Epicardial Access Kit
- Where
- Czechia
- Volunteers
- 13 people
- Sponsor
- Talon Surgical
Ventricular Arrythmia
China Inherited Ventricular Arrhythmias Registry
This is an observational, prospective, multi-center registry, aiming at building a risk stratification for malignant inherited ventricular arrhythmias, including Brugada syndrome(Brs)、Long QT syndrome(LQTS)、Short QT…
- Trial name
- NCT03880708
- Where
- China
- Volunteers
- 500 people
- Sponsor
- China National Center for Cardiovascular Diseases
Ventricular Arrythmias
Efficacy of the ATP Switch Automatic Programming in Implantable Cardioverter Defibrillator (ICD) and Cardiac Resynchronization Therapy Defibrillator (CRT-D) Implanted Patients
Primary objective is to assess the efficacy of the new ATP Autoswitch function in simple, dual or triple chamber ICD.
- Trial name
- ASAP (NCT01169246)
- Where
- France
- Volunteers
- 1,254 people
- Sponsor
- MicroPort CRM
Heart Failure, Ventricular Arrythmias
Safety and Efficacy of Automatic Testing Feature in New ICDs and CRT-Ds
This study is a prospective, non-randomized, multi-center clinical trial that will assess the safety and effectiveness of investigational models of the Promote™ RF CRT-D and Current™ RF ICD devices.
- Trial name
- NCT00746356
- Testing
- Testing of the autocapture features of the device
- Where
- 5 sites in United States
- Volunteers
- 128 people
- Sponsor
- Abbott Medical Devices
Tetralogy of Fallot, Implantable Defibrillator User
French National Registry of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator
National french registry of patients with tetralogy of Fallot and implantable cardioverter defibrillator.
- Conditions
- Tetralogy of Fallot, Implantable Defibrillator User, Congenital Heart Disease, Sudden Cardiac Death
- Trial name
- DAI-T4F (NCT03837574)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Paris Sudden Death Expertise Center
Ventricular Arrythmia
China Structural Ventricular Arrhythmias Registry
This is an observational, prospective, multi-center registry ,aiming at building a risk stratification for malignant structural ventricular arrhythmias.
- Trial name
- NCT03821051
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Atrial Arrhythmia, Ventricular Arrythmia
Real Zero Fluoroscopy Catheter Ablation.
A Retrospective Propensity Matched Study comparing: real zero fluoroscopy catheter ablation conventional fluoroscopy catheter ablation without 3D system conventional fluoroscopy catheter ablation with 3D system
- Conditions
- Atrial Arrhythmia, Ventricular Arrythmia, Arrhythmia, Arrhythmias, Cardiac
- Trial name
- ZERO-Fluoro (NCT03458273)
- Testing
- Zero fluoroscopy ablation, Conventional ablation without 3D, Conventional ablation with 3D
- Where
- 3 sites in Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Lublin