Clinical trials: Ventricular Fibrillation
Cardiomyopathy, Arrhythmia-induced Cardiomyopathy (AiCM)
Characterization of Arrhythmia-induced Cardiomyopathy
The goal of the this observational study is to gather clinically available data on patients presenting with a suspicion for arrhythmia-induced cardiomyopathy (AiCM) at the University Hospital Basel.
- Trial name
- NCT05662293
- Testing
- Data collection: Major adverse cardiovascular event (MACE) assessment questionnaire (prospective part), Data collection: Quality of Life (QoL) Questionnaire (prospective part), Data collection (retrospective study)
- Where
- Switzerland
- Volunteers
- 2,700 people
- Sponsor
- University Hospital, Basel, Switzerland
Myocardial Infarction, Coronary Artery Disease
Arrhythmias in Post-Myocardial Infarction Patients
Patients are screened for significant arrhythmias and other possibly significant ECG-patterns directly after discharge and two weeks after myocardial infarction using wearable devices.
- Conditions
- Myocardial Infarction, Coronary Artery Disease, Arrythmia, ECG Electrical Alternans
- Trial name
- NCT03231826
- Where
- Finland
- Volunteers
- 445 people
- Sponsor
- Tampere University
Heart Failure, Cardiomyopathies
The Multicenter Cardiology Monitoring Platform Registry
The multicenter Cardiology Monitoring Platform registry (mCMP-registry) is a prospective observational registry including multi-omics (diagnostic) measurements performed as part of routine clinical care, bio-banking (optional)…
- Conditions
- Heart Failure, Cardiomyopathies, Atrial Fibrillation, Ventricular Arrythmia
- Trial name
- mCMPregistry (NCT04976348)
- Where
- Netherlands
- Volunteers
- 40,000 people
- Sponsor
- Maastricht University Medical Center
Ventricular Arrhythmias and Cardiac Arrest
Using Mirabegron to Control Arrhythmia-1
To evaluate mirabegron's effect on ventricular arrhythmia control. The study will be conducted in ambulatory patients with ventricular tachycardia (VT), organic heart diseases, and an implantable cardioverter-defibrillator (ICD).
- Trial name
- MACH-1 (NCT07566208)
- Testing
- Mirabegron
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Hypertension, Atrial Fibrillation
Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial
In patients with a standard indication for pacing and no previous history of AF, detection of Atrial High Rate Episodes predicts an increased risk of stroke and systemic embolism.
- Trial name
- NCT00256152
- Testing
- AF Suppression Pacing Algorithm
- Where
- Canada
- Volunteers
- 2,580 people
- Sponsor
- Abbott Medical Devices
Out-of-hospital Cardiac Arrest
Rapid Infusion of Cold Normal Saline During CPR for Patients With Out-of-hospital Cardiac Arrest
That paramedic core cooling during CPR using a rapid infusion of ice-cold (4 degrees C) large-volume (30mL/kg) normal saline improves outcome at hospital discharge compared with standard care in patients with out-of-hospital…
- Trial name
- RINSE (NCT01173393)
- Testing
- PARAMEDIC COOLING
- Where
- Australia
- Volunteers
- 1,220 people
- Sponsor
- Ambulance Victoria
Sinus Rhythm, Atrial Fibrillation
Prevention of Stroke and Sudden Cardiac Death by Recording of 1-Channel Electrocardiograms
Single-channel electrocardiograms (lead I of 12-lead surface ECG; 30 seconds) will be collected from subjects/patients at 11 clinical centers in Germany to train an Artificial Intelligence in the automatic diagnosis of regular…
- Conditions
- Sinus Rhythm, Atrial Fibrillation, Atrial Premature Complexes, Ventricular Premature Complexes
- Trial name
- PRICE (NCT04637230)
- Testing
- Electrocardiogram analysis by Artificial Intelligence
- Where
- Germany
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- A-Rhythmik GmbH
Ventricular Tachycardia, Ventricular Fibrillation
Post-marketing Registration Study of Nifekalant Hydrochloride (NIF) Injection
Retrospective and Prospective single arm, observational study to evaluate efficacy and safety of NIF in the treatment of ventricular tachycardia and ventricular fibrillation.
- Trial name
- NCT03853369
- Testing
- Nifekalant hydrochloride
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sichuan Baili Pharmaceutical Co., Ltd.
Out-of-Hospital Cardiac Arrest, Death, Sudden, Cardiac
The Use of Mobile Phones in Out of Hospital Cardiac Arrest to Increase Bystander CPR
Death from cardiac disease is one of the most common causes of death in the western world. The majority of these deaths takes place outside hospital as sudden cardiac death.
- Conditions
- Out-of-Hospital Cardiac Arrest, Death, Sudden, Cardiac, Heart Diseases, Ventricular Fibrillation
- Trial name
- RUMBA (NCT01789554)
- Testing
- MLS dispatch for bystander CPR
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Karolinska Institutet
Ventricular Tachycardia, Ventricular Flutter
Feature Assessment Study for Indications Based Programming
The purpose of this evaluation is to assess the acceptance level of specific programming recommendations based on the patient's clinical needs and primary indications when using the feature 'Indications Based Programming' (IBP)…
- Conditions
- Ventricular Tachycardia, Ventricular Flutter, Ventricular Fibrillation, Heart Failure
- Trial name
- FASt-IBP (NCT00711893)
- Testing
- Cognis 100-D, Teligen DR and VR 100 HE
- Where
- 28 sites in Austria, Belgium and 9 more
- Volunteers
- 301 people
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation, Heart Failure
The Use of Ranolazine for Atrial Fibrillation and Diastolic Heart Failure
The purpose of this study is to evaluate the efficacy of ranolazine in the prevention of recurrent atrial fibrillation in post-cardioversion patients with heart failure and preserved ejection fraction.
- Trial name
- RAD HF (NCT01887353)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Intermountain Health Care, Inc.
Atrial Fibrillation (AF), Atrial Fibrillation With Rapid Ventricular Response
Comparing Two Heart Medicines for Fast, Irregular Heartbeat (Atrial Fibrillation)
The goal of this clinical trial is to learn whether intravenous verapamil or intravenous metoprolol controls heart rate more effectively in adult patients who arrive at the emergency department with atrial fibrillation and a fast…
- Trial name
- NCT07706075
- Testing
- Verapamil Hydrochloride, Metoprolol tartrate
- Volunteers
- 120 people
- Sponsor
- Muhammad Ali Javed
COVID, Arrhythmia
COVIDAR - Arrhythmias in COVID-19
BACKGROUND AND RATIONALE: There is very limited literature available on the arrhythmia occurrence in the context of an infection by the SARS-CoV2 virus.
- Conditions
- COVID, Arrhythmia, Torsades de Pointe Caused by Drug, Qt Interval, Variation in
- Trial name
- COVIDAR (NCT04437901)
- Where
- 5 sites in Belgium, Italy and 3 more
- Volunteers
- 10,000 people
- Sponsor
- Hospital Clinic of Barcelona
Chronic Stable Angina, Coronary Artery Disease
Safety of Amiodarone and Ranolazine Together in Patients With Angina
Ranolazine is an effective and remarkably safe agent for the treatment of patients with chronic stable angina, but its inhibition of voltage gated potassium channels and electrocardiogram (EKG) corrected QT (QTc) prolongation…
- Conditions
- Chronic Stable Angina, Coronary Artery Disease, Atrial Fibrillation, Ventricular Tachycardia
- Trial name
- SARA (NCT01558830)
- Testing
- ranolazine
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cardiovascular Consultants of Nevada
Myocardial Infarction
MAP-IDM: Identification of Molecular Markers of Sudden Death at the Acute Phase of Myocardial Infarction
We propose a comparative case-control study on the 2 following groups of patients: Cases: 500 patients with ventricular fibrillation at the acute phase of myocardial infarct, Controls: 500 patients without ventricular…
- Trial name
- MAP-IDM (NCT00859300)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 1,011 people
- Sponsor
- Hospices Civils de Lyon
Heart Failure, Atrial Fibrillation (AF)
AI-Based Cardiac Analysis Using 12-Lead and 1-Lead ECG
This pilot study is designed to evaluate the clinical performance and utility of the SmartECG-EF software in patients undergoing evaluations at Inha University Hospital.
- Conditions
- Heart Failure, Atrial Fibrillation (AF), Electrocardiogram
- Trial name
- NCT07844434
- Testing
- SmartECG-EF
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Inha University Hospital
Ventricular Tachycardia, Ventricular Fibrillation
SD01 Master Study (Safety and Efficacy Study)
The study is designed to confirm safety and efficacy of the SD01 ICD (implantable cardioverter-defibrillator) lead.
- Conditions
- Ventricular Tachycardia, Ventricular Fibrillation, Heart Failure
- Trial name
- NCT01836497
- Testing
- SD01 ICD lead
- Where
- 14 sites in Czechia, France and 3 more
- Volunteers
- 163 people
- Sponsor
- Biotronik SE & Co. KG
Arrhythmogenic Cardiomyopathy (AC, ARVD/C), Ventricular Tachycardia (VT)
Treatment Registry of Arrhythmias, Complications and Electrocardiograms in Arrhythmogenic CardioMyopathies
TRACE-ACM is a multicenter, retrospective, observational study of patients with arrhythmogenic cardiomyopathy who received an implantable cardioverter-defibrillator (ICD) and had documented ventricular tachyarrhythmias.
- Conditions
- Arrhythmogenic Cardiomyopathy (AC, ARVD/C), Ventricular Tachycardia (VT), Ventricular Fibrillation, ICD
- Trial name
- TRACE-ACM (NCT07688200)
- Volunteers
- 300 people
- Sponsor
- Policlinico Casilino ASL RMB
Ventricular Fibrillation
VERRARI - "Are Ventricular Arrhythmic Episodes Reduced by Rate Response in ICDs?"
"The purpose of this study is to evaluate the influence of the rate response function of implantable cardioverter defibrillators (ICDs) on the frequency of ventricular arrhythmias in patients with an ICD."
- Trial name
- NCT00180427
- Testing
- ICD
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- Guidant Corporation
Cardiac Arrest, Ventricular Fibrillation
VectOr ChAnge defibriLlatIon in Refractory Shockable rhyThms
Management of cardiac arrest according to published guidelines has remained largely unchanged for a decade. Thames Valley Air Ambulance provide Critical Care Paramedic and Physician teams who respond to cardiac arrests and offer…
- Conditions
- Cardiac Arrest, Ventricular Fibrillation, Ventricular Tachycardia
- Trial name
- VOCALIST (NCT05926973)
- Testing
- Enhanced cardiac arrest bundle
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Thames Valley Air Ambulance