Clinical trials: Ventricular Tachyarrhythmia
Ventricular Tachycardia, Arrhythmia
Imaging With a Radio Tracer to Guide VT Ablations
Some patients are at risk for life-threatening fast heart rates. These can frequently be treated by using a catheter inside the heart to burn away the cells that create the fast heart rates.
- Trial name
- NCT01250912
- Testing
- 123I-metaiodobenzylguanidine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Maryland, Baltimore
Ventricular Tachycardia
Non-invasive Ablation of Ventricular Tachycardia
Phase I/II study of 4-D Navigated Non-invasive radiosurgical ablation of ventricular tachycardia (NIRA-VT).
- Trial name
- NCT03601832
- Testing
- 4-D navigated stereotactic radiosurgical ablation
- Where
- 3 sites in Czechia
- Volunteers
- 10 people
- Sponsor
- University Hospital Ostrava
Chagas Cardiomyopathy, Ventricular Arrythmia
Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease
Ventricular tachycardia (VT) is the main cause of sudden death in patients with structural heart diseases. The use of ICD (implantable cardio-defibrillator) could prevent sudden death, however, the occurrence of repetitive shock…
- Trial name
- NCT04239144
- Testing
- Bilateral sympathectomy, Catheter ablation
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo General Hospital
Myocardial Infarction, Ventricular Tachycardia
Risk Stratification of VT / VF After Myocardial Infarction Based on Cardiac MRI 2
Implantable cardioverter-defibrillators (ICD) are currently recommended (ESC guidelines 2015) for the primary prevention of sudden cardiac death (SCD) in patients with a remote myocardial infarction (MI) and a low (≤35%) left…
- Conditions
- Myocardial Infarction, Ventricular Tachycardia, Ventricular Fibrillation
- Trial name
- TVScreen-2 (NCT05226234)
- Testing
- MRI
- Where
- France
- Volunteers
- 275 people
- Sponsor
- Central Hospital, Nancy, France
Catecholaminergic Polymorphic Ventricular Tachycardia
Flecainide for Catecholaminergic Polymorphic Ventricular Tachycardia
The purpose of this study is to test whether the addition of oral flecainide to standard therapy will reduce ventricular ectopy on exercise test compared to placebo plus standard therapy in patients with Catecholaminergic…
- Trial name
- NCT01117454
- Testing
- Flecainide Acetate, Beta blocker
- Where
- 10 sites in United States
- Volunteers
- 14 people
- Sponsor
- Vanderbilt University Medical Center
Ischemic Ventricular Tachycardia
Dynamic Substrate Mapping (DSM) for Ischemic VT
This is a prospective, non-randomized study to determine the feasibility of using a new technique called Dynamic Substrate Mapping (DSM) to help guide the treatment of ischemic ventricular tachycardia (IVT).
- Trial name
- DSM (NCT00558857)
- Testing
- Dynamic Substrate Mapping-guided ablation
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Abbott Medical Devices
Ventricular Tachycardia
MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry
Data collection registry for patients with ventricular tachycardia to help physicians give better care for patients clinically and procedurally.
- Trial name
- MANAGE-VT (NCT06455488)
- Testing
- Ventricular Tachycardia Ablation, ICD Implant, Antiarrhythmic drug
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- CorVita Science Foundation
Cardiac Arrhythmias, Acute Myocardial Infarction (AMI)
Predict Arrhythmia Risk Using Intelligent Software
Cardiac arrhythmias frequently occur in patients admitted to the Coronary Care Unit (CCU). The majority of these patients are treated for an acute myocardial infarction, which carries an increased risk of life-threatening…
- Conditions
- Cardiac Arrhythmias, Acute Myocardial Infarction (AMI), Ventricular Tachycardia (VT), Ventricular Fibrillation
- Trial name
- PARIS (NCT07792694)
- Where
- Netherlands
- Volunteers
- 3,000 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Ischemic Cardiomyopathy, Ventricular Tachycardia
Repeated Endocardial Mapping for Efficacy Assessment After Catheter Ablation for Ischemic Ventricular Tachycardia
Patients with ischemic ventricular tachycardia (VT) are frequently treated with radiofrequency catheter ablation. The efficacy of catheter ablation is limited for various reasons; one of those being incomplete myocardial and…
- Trial name
- REMAP-VT (NCT05713357)
- Testing
- Catheter ablation
- Where
- Slovenia
- Volunteers
- 20 people
- Sponsor
- University Medical Centre Ljubljana
Post-myocardial Infarction Ventricular Tachycardia
Facilitating Catheter Guidance to Optimal Site for VT Ablation
Each year in the UK, approximately 150,000 people have a heart attack when the blood supply to their heart is compromised. As a result, affected regions of the heart can become diseased and scarred.
- Trial name
- CPS (NCT03862989)
- Testing
- Radiofrequency catheter ablation
- Where
- United Kingdom
- Sponsor
- University of Exeter
Syncope, Bradycardia
Registry of Device Implantation
The implantable device therapy for cardiac arrhythmias has been an established therapy, and one of the common standard procedures in cardiac clinical practice.
- Conditions
- Syncope, Bradycardia, Tachycardia, Sudden Cardiac Death
- Trial name
- NCT03360227
- Testing
- implantation of cardiac devices
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Ventricular Tachycardia, Ischemic Cardiomyopathy
SMART Identification of Ventricular Tachycardia Isthmus
Context : Ventricular tachycardia (VT) are serious heart rhythm disorders which can lead to sudden death. A curative treatment for these abnormalities in the cardiac electrical conduction system is possible through an…
- Trial name
- SMARTIS (NCT04852497)
- Testing
- Ventricular tachycardia ablation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Heart Failure, Ventricular Tachycardia
Biomarkers in Risk Stratification of Sustainted Ventricular Tachycardia or Electrical Storm After Ablation
Prevalence of HF reaches 1-2% of developed populations, and consequently a significant problem becomes more frequent occurrence of ventricular arrhythmias (VA) - sustained ventricular tachycardia (sVT) and electrical storm (ES)…
- Conditions
- Heart Failure, Ventricular Tachycardia, Ventricular Dysfunction
- Trial name
- STORM (NCT02784912)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Warsaw
Polymorphic Ventricular Tachycardia, Heart Failure
Radiofrequency Ablation for Polymorphic Ventricular Tachycardia With Heart Failure (RFCA for PMVT-HF)
This is a prospective, randomized, controlled trial to investigate the efficacy of radiofrequency catheter ablation (RFCA) combined with guideline-directed medical therapy (GDMT) compared to GDMT alone in patients with…
- Trial name
- NCT07130175
- Testing
- Radiofrequency Catheter Ablation, Guideline-Directed Medical Therapy (GDMT)
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Qian Feng
Ventricular Arrhythmia, Ventricular Tachycardia (V-Tach)
Proton Radiosurgery for the Treatment of Malignant Ventricular Tachyarrhythmias
Ventricular arrhythmias (VAs) are the leading cause of sudden cardiac death (SCD) worldwide. The implantable defibrillator (ICD) increases survival in patients at risk of VA, with data of superiority to antiarrhythmic drugs.
- Trial name
- TOVEL (NCT06769451)
- Testing
- Stereotactic Arrhythmia Radioablation (STAR) with Proton Therapy
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Azienda Sanitaria Universitaria Integrata del Trentino
Ventricular Tachycardia
Modification of Rhythmic Risk Assessment by Ventricular Tachycardia Ablation
Sudden cardiac death is a frequent cause of cardiovascular mortality. Numerous rhythmic risk assessment criterion have been described targeting the substratum, the cardiac nervous tone or the trigger of arrhythmias.
- Trial name
- NCT03453645
- Testing
- ventricular tachycardia ablation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Ventricular Tachycardia
Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation
The purpose of this research study is to evaluate the safety and feasibility of the Impella 2.5 Circulatory Support System for use during mapping and ablation of ventricular tachycardia in the setting of Ventricular dysfunction.
- Trial name
- PERMIT1 (NCT01294267)
- Testing
- Circulatory Support System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vivek Reddy
Ventricular Tachycardia, Atrial Fibrillation
Vein of Marshall Ethanol Infusion for Persistent Atrial Fibrillation
The broad, long-term objective of this project is to evaluate the therapeutic value of vein of Marshall (VOM) ethanol infusion when added to catheter ablation of atrial fibrillation (AF).
- Trial name
- VOM-R01 (NCT01898221)
- Testing
- Ethanol, Ablation
- Where
- 12 sites in United States
- Volunteers
- 343 people
- Sponsor
- The Methodist Hospital Research Institute
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy
Mechanical Alternans Study
The purpose of this study is to determine whether mechanical alternans (alternating strong and weak heart beats with a constant beat-to-beat interval), can be used to predict malignant ventricular arrhythmias, requiring…
- Conditions
- Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy, Heart Failure
- Trial name
- MAS (NCT01557465)
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Johns Hopkins University
Ventricular Tachycardia (VT)
Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial
The current standard of care for ventricular tachycardia (VT) includes the use of medicine called anti-arrhythmic drugs (AADs) and Implantable Cardioverter Defibrillator (ICD) therapy.
- Trial name
- PAUSE-SCD (NCT02848781)
- Testing
- Implantable Cardioverter Defibrillator (ICD), Catheter Ablation
- Where
- 12 sites in United States, China and 3 more
- Volunteers
- 180 people
- Sponsor
- University of Arizona