Clinical trials: Ventricular Tachycardia (VT)
Ischemic Ventricular Tachycardia
Dynamic Substrate Mapping (DSM) for Ischemic VT
This is a prospective, non-randomized study to determine the feasibility of using a new technique called Dynamic Substrate Mapping (DSM) to help guide the treatment of ischemic ventricular tachycardia (IVT).
- Trial name
- DSM (NCT00558857)
- Testing
- Dynamic Substrate Mapping-guided ablation
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Abbott Medical Devices
Scar-related Monomorphic Sustained VT
Pivotal Study to Evaluate Catheter Ablation in Patients With Scar-Related Monomorphic Sustained VT in the Ventricular Ectopy and Reduction in Tachycardia Ablation Studies Program VERITAS SCAR VT
The VERITAS VT Study is a prospective, multicenter, international, single-arm clinical investigation designed to evaluate the safety and effectiveness of the FieldForce™ Pulsed Field Ablation System for the treatment of sustained…
- Trial name
- NCT07794215
- Testing
- System is an investigational catheter-based device designed to deliver pulsed field ablation energy to cardiac tissue for the treatment of sustained monomorphic VT
- Volunteers
- 180 people
- Sponsor
- Field Medical
Ventricular Tachycardia
VT Cryoablation System Post-Market Clinical Follow-up (PMCF) Study
The PMCF is a prospective, single-arm, multi-center, controlled study of up to 130 patients designed to collect safety and performance data regarding the use of the Adagio VT Cryoablation System in the treatment of recurrent…
- Trial name
- NCT06384599
- Testing
- VT Cryoablation System
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Adagio Medical
Ventricular Tachycardia, Arrythmia
SERF VT Ablation Early Feasibility Study (EFS)
This is an early feasibility, non-randomized, open-label, single group, interventional study to be conducted in up to 20 US subjects to evaluate the technical feasibility of the Durablate Catheter and Thermedical Ablation System…
- Conditions
- Ventricular Tachycardia, Arrythmia, Heart Diseases, Cardiovascular Diseases
- Trial name
- SERF VT EFS (NCT03628534)
- Testing
- Saline Enhanced Radiofrequency (SERF) ablation
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Thermedical, Inc.
Ventricular Tachycardia, Monomorphic
Fast VT Episodes Are Terminated by ATP One Shot
Many arrhythmias detected in the ventricular fibrillation (VF)-zone picture monomorphic ventricular tachycardia (VT) and, hence, could be terminated by antitachycardia pacing (ATP) treatment.
- Trial name
- FavoriteATP (NCT00617578)
- Testing
- ATP One Shot ON, ATP One Shot OFF
- Where
- 14 sites in Austria, Finland and 2 more
- Volunteers
- 194 people
- Sponsor
- Biotronik SE & Co. KG
Ventricular Tachycardia
FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study
This clinical investigation is intended to demonstrate the safety and effectiveness of ventricular ablation therapy using the FlexAbility Sensor Enabled Ablation Catheter in patients with drug-refractory monomorphic ventricular…
- Trial name
- LESS-VT (NCT03490201)
- Testing
- Market Approved RF Ablation System, FlexAbility SE Ablation Catheter
- Where
- 32 sites in United States, Australia and 6 more
- Volunteers
- 592 people
- Sponsor
- Abbott Medical Devices
Ventricular Tachycardia, Arrythmia
Rook Epicardial Access Device Study
The purpose of this study is to confirm the efficacy and safety of the Talon Surgical Rook® Epicardial Access Kit as a pericardial access device.
- Trial name
- NCT03427333
- Testing
- The Rook® Epicardial Access Kit
- Where
- Czechia
- Volunteers
- 13 people
- Sponsor
- Talon Surgical
Monomorphic Ventricular Tachycardia
Cryoablation for Monomorphic Ventricular Tachycardia (CryoCure-VT)
A prospective, single-arm, multi-center, pre-market, clinical study designed to provide safety and performance data regarding the use of the Adagio Medical VT Cryoablation System in the treatment of ventricular tachycardia.
- Trial name
- CryoCure-VT (NCT04893317)
- Testing
- Ablation in the ventricles with the Adagio Medical VT Cryoablation System
- Where
- 7 sites in Belgium, Canada and 4 more
- Volunteers
- 64 people
- Sponsor
- Adagio Medical
Ventricular Tachycardia
VT Ablation in the iCMR
The VISABL-VT is a prospective, single-arm, multi-center, interventional investigation of the safety and efficacy of radiofrequency (RF) ablation of ventricular tachycardia associated with ischemic cardiomyopathy performed with…
- Trial name
- VISABL-VT (NCT05543798)
- Testing
- Vision-MR Ablation Catheter 2.0
- Where
- 3 sites in Germany, Netherlands
- Volunteers
- 64 people
- Sponsor
- Imricor Medical Systems
Ventricular Tachycardia
Unpinning Termination Therapy for VT (US)
This observation study evaluates the safety and performance of UPT therapy in subjects during either an indicated ventricular tachycardia ablation procedure or an ICD implant procedure.
- Trial name
- NCT03093051
- Testing
- Unpinning Termination therapy
- Where
- 7 sites in United States
- Volunteers
- 6 people
- Sponsor
- Cardialen, Inc.
Ventricular Arrhythmia
Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator
The primary objective of this study is to evaluate the effect of eleclazine (GS-6615) compared to placebo on the overall occurrence of appropriate implantable cardioverter-defibrillator (ICD) interventions (antitachycardia pacing…
- Trial name
- TEMPO (NCT02104583)
- Testing
- Eleclazine
- Where
- 84 sites in United States, Canada and 7 more
- Volunteers
- 313 people
- Sponsor
- Gilead Sciences
Ventricular Tachycardia, Sustained, Ventricular Tachycardia, Monomorphic
Cryoablation for Monomorphic Ventricular Tachycardia (VTS)
The objective of this clinical study is to evaluate the safety and effectiveness of the Adagio Medical vCLAS Ventricular Ablation System (including VTS Catheter and Console) in the ablation treatment of Sustained Monomorphic…
- Trial name
- FULCRUM-VT (NCT07650032)
- Testing
- Ultra Low Temperature Ablation (ULTA)
- Where
- 10 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Adagio Medical
Ventricular Tachycardia
Stereotaxis Study To Obliterate Persistent Ventricular Tachycardia
This is a prospective, non-randomized, multi-center clinical case series evaluating the outcomes of the magnetic navigation system in ventricular tachycardia (VT) cases.
- Trial name
- STOP-VT (NCT00851279)
- Testing
- Magnetic irrigated ablation catheter
- Where
- 4 sites in United States, Czechia and 1 more
- Volunteers
- 53 people
- Sponsor
- Stereotaxis
Sustained VT
Cryoablation for Monomorphic Ventricular Tachycardia
The objective of this clinical study is to evaluate the safety and effectiveness of the Adagio VT Cryoablation System in the ablation treatment of Sustained Monomorphic Ventricular Tachycardia (SMVT)
- Trial name
- FULCRUM-VT (NCT05675865)
- Testing
- cryoablation procedure
- Where
- 15 sites in United States, Canada
- Volunteers
- 206 people
- Sponsor
- Adagio Medical
Ventricular Tachycardia (VT), Ventricular Fibrillation
Evolution of Intracardiac Electrograms Recorded by Left Bundle Branch Pacing Lead in Patients With ICD or CRT-D
The goal of this observational study is to investigate the changes of LBB EGM during daily activities and overdrive pacing at the time of peri-implantation and up to 6-month follow-ups of ICD/CRT-D patients.
- Trial name
- NCT06745778
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
CPVT1, Heart Defects, Congenital
Effectiveness of CRD-4730 in Participants With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
This is a Phase 2, multicenter, double-blind, sponsor unblinded, placebo-controlled, single-dose clinical study of CRD-4730 to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of CRD-4730 when…
- Conditions
- CPVT1, Heart Defects, Congenital, Heart Diseases, Ventricular Tachycardia
- Trial name
- CPVT (NCT06005428)
- Testing
- CRD-4730
- Where
- 11 sites in United States, Canada and 2 more
- Volunteers
- 7 people
- Sponsor
- Cardurion Pharmaceuticals, Inc.