Clinical trials: Ventricular Tachycardia Ablation
Ventricular Tachycardia
Modification of Rhythmic Risk Assessment by Ventricular Tachycardia Ablation
Sudden cardiac death is a frequent cause of cardiovascular mortality. Numerous rhythmic risk assessment criterion have been described targeting the substratum, the cardiac nervous tone or the trigger of arrhythmias.
- Trial name
- NCT03453645
- Testing
- ventricular tachycardia ablation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Ventricular Tachycardia
A Study of Early Robotic Ablation by Substrate Elimination of Ventricular Tachycardia
Ventricular tachycardia (VT) is an abnormal rapid heartbeat which occurs after a heart attack and can cause sudden death. Patients at risk of this rhythm disturbance usually receive an implantable cardioverter defibrillator (ICD)…
- Trial name
- ERASE-VT (NCT01182389)
- Testing
- Robotic VT Ablation, Conventional Therapy
- Where
- 3 sites in United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Ventricular Tachycardia
Stereotaxis Study To Obliterate Persistent Ventricular Tachycardia
This is a prospective, non-randomized, multi-center clinical case series evaluating the outcomes of the magnetic navigation system in ventricular tachycardia (VT) cases.
- Trial name
- STOP-VT (NCT00851279)
- Testing
- Magnetic irrigated ablation catheter
- Where
- 4 sites in United States, Czechia and 1 more
- Volunteers
- 53 people
- Sponsor
- Stereotaxis
Ventricular Tachycardia
Endo- and Epicardial vs. Endocardial Ablation of Ventricular Tachycardia in Patients With Cardiac Disease
A significant portion of patients with cardiac diseases like coronary artery disease (CAD), dilated cardiomyopathy (DCM) and arrhythmogenic right ventricular cardiomyopathy (ARVC) develops ventricular tachycardia (VT).
- Trial name
- VTeee (NCT01767220)
- Testing
- Strategy 1 - endocardial ablation, Strategy 2 - endocardial and epicardial ablation
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Rostock
Ventricular Tachycardia
Physiologically Guided VT Ablation
The purpose of this study is to determine the efficacy of VT ablation guided by functional evaluation of the substrate to specifically target the reentry-vulnerable zones in patients with infarct-related VT.
- Trial name
- NCT04004624
- Testing
- Ablation
- Volunteers
- 80 people
- Sponsor
- Center for Cardiovascular Reseach and Innovation
Ventricular Tachycardia, Ischemic Cardiomyopathy
Catheter Ablation for Nonsustained Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy
Despite established implantable cardioverter-defibrillator (ICD) therapy and catheter ablation for sustained ventricular tachycardia (VT) in patients with ischemic heart disease (IHD) and reduced left ventricular ejection…
- Conditions
- Ventricular Tachycardia, Ischemic Cardiomyopathy, Reduced LVEF
- Trial name
- nsVT (NCT03147027)
- Testing
- VT ablation, medication
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Ventricular Tachycardia, Premature Ventricular Contraction
DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation
The purpose of this study is to learn if taking a drug called direct oral anticoagulant after an ablation procedure keeps blood clots from forming and lowers the chance of having a stroke in patients with ventricular tachycardia…
- Conditions
- Ventricular Tachycardia, Premature Ventricular Contraction, Stroke
- Trial name
- STROKE-VT (NCT02666742)
- Testing
- DOAC, Aspirin
- Where
- 5 sites in United States, India
- Volunteers
- 246 people
- Sponsor
- Kansas City Heart Rhythm Institute
Ventricular Tachycardia, Myocardial Fibrosis
Ventricular Tachycardia Ablation and Myocardial Scar Characterization With Magnetic Resonance
Previous monocentric experiences have already highlighted the role of preoperative cardiac imaging, in particular of cardiac magnetic resonance (CMR) and tomography (CT), in improving the ablation results of scar-related…
- Trial name
- VOYAGE (NCT04694079)
- Testing
- Group 1, CMR-guided/aided VT ablation, Group 2, CMR-aided VT ablation, Group 3, Electroanatomical guided ablation
- Where
- 7 sites in Italy
- Volunteers
- 104 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Defibrillators, Implantable, Tachycardia, Ventricular
Catheter Ablation Versus Amiodarone for Shock Prophylaxis in Defibrillator Patients With Ventricular Tachycardia
Implantable Cardioverter Defibrillators (ICDs) provide a shock or pacing therapy to bring back a normal heart beat when a patient experiences a dangerous abnormal heart rhythm such as ventricular tachycardia (VT).
- Trial name
- CEASE-VT (NCT01097330)
- Testing
- Ablation, Amiodarone
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 12 people
- Sponsor
- Population Health Research Institute
Ventricular Tachycardia (VT)
Dynamic Voltage Mapping to Personalise the Ventricular Tachycardia Substrate
Ventricular tachycardia (VT) is a life-threatening heart rhythm disorder and one of the commonest causes of heart-related sudden death. It often affects people who have had a heart attack or other structural heart damage.
- Trial name
- DYNAMITE-VT (NCT07573579)
- Testing
- Dynamic Voltage Mapping, Standard of Care Ablation
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Ventricular Tachycardia, ICD
Improving Patient Reported Outcome Measures in Catheter Ablation
This study will assess whether more frequent measurement of patient reported outcome measures (PROMs) - specifically health related quality of life (HRQL) - can improve the evaluation of the clinical effectiveness and…
- Conditions
- Ventricular Tachycardia, ICD, Quality of Life
- Trial name
- NCT04499326
- Testing
- Validated quality of life questionnaire (EQ-5D & C-CAP)
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Barts & The London NHS Trust
Ventricular Tachycardia, Ischemic Heart Disease
Pulsed Field Ablation for Post-Infarction Ventricular Tachycardia
ASCEND is a randomized controlled open-label pilot study evaluating the safety and effectiveness of pulsed field ablation (PFA) with the novel FARAPOINT catheter compared to the standard radiofrequency (RFA) ablation with…
- Conditions
- Ventricular Tachycardia, Ischemic Heart Disease, Sustained VT
- Trial name
- ASCEND-VT (NCT06891456)
- Testing
- RFA Ablation, PFA Ablation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Pasquale Santangeli
Heart Failure
Primary Preventive Ventricular Tachycardia Ablation In High-Risk Patients Who Receive A Prophylactic Implantable Cardioverter Defibrillator
This prospective, multicenter, open-label, randomized-controlled trial compares two treatment strategies in high-risk ischemic cardiomyopathy (ICM) patients referred for primary ICD implantation.
- Trial name
- PREVENT-VT (NCT06543173)
- Testing
- Prophylactic Catheter-based VT Ablation
- Where
- 5 sites in Denmark, France and 1 more
- Volunteers
- 62 people
- Sponsor
- University of Rochester
Ventricular Tachycardia, Ischemic Cardiomyopathy
Venous Ethanol for Ventricular Tachycardia
Comparative effectiveness randomized clinical trial, comparing endocardial radiofrequency ablation alone vs radiofrequency ablation combined with venous ethanol in patients with ischemic ventricular tachycardia -Venous Ethanol…
- Trial name
- VELVET (NCT05511246)
- Testing
- Venous ethanol, Catheter ablation
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- The Methodist Hospital Research Institute
Structural Heart Disease
Optimised Decrement Evoked Potential (DeEP) Mapping to Guide Ventricular Tachycardia (VT) Ablation in Patients With Structural Heart Disease VT
Ventricular tachycardia (VT) is a life-threatening heart rhythm disorder. Special pacemakers called implantable cardiac defibrillators (ICDs) help treat VT episodes, however they do not prevent the VT episodes from occurring.
- Trial name
- Opto-DeEP (NCT06937983)
- Testing
- Optimised DeEP-guided ablation
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Ventricular Tachycardia (V-Tach), Implantable Cardioverter Defibrillator (ICD)
Parallel Mapping for Ventricular Tachycardia
Catheter ablation in patients with ventricular tachycardia using a new mapping algorithm called, parallel mapping, that is aimed to increase the specificity of mapping and the outcome of ablation.
- Conditions
- Ventricular Tachycardia (V-Tach), Implantable Cardioverter Defibrillator (ICD), Arrythmia
- Trial name
- NCT04477499
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- The Cleveland Clinic
Ventricular Arrythmia, Ventricular Premature Complexes
Zero-fluoroscopic Ablation Versus Conventional Fluoroscopic Ablation for the Treatment of Ventricular Arrhythmias
This study is intended to compare the feasibility, safety and efficacy of a zero-fluoroscopy approach using Ensite NavX as the only imaging modality with conventional fluoroscopic approach for the catheter ablation of idiopathic…
- Conditions
- Ventricular Arrythmia, Ventricular Premature Complexes, Ventricular Tachycardia
- Trial name
- ZFOVA (NCT03041519)
- Testing
- Zero-fluoroscopy ablation, Conventional fluoroscopy ablation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tongji Hospital
Ventricular Tachycardia, Cardiomyopathy
Renal Denervation In Patient Undergoing VT Ablation:Combined Renal Denervation and VT Ablation vs. Simply VT Ablation
Study hypothesis: With optimal medical therapy and repeated ablations, an additional renal denervation may have protective effects in terms of vegetative intrinsic activity and lead to a significant reduction in VT Burdens.
- Trial name
- ARDEVAT (NCT02071511)
- Testing
- Ablation of ventricular arrhythmias, Ablation of ventricular arrhythmias + renal denervation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Ventricular Tachycardia
VT Ablation in the iCMR
The VISABL-VT is a prospective, single-arm, multi-center, interventional investigation of the safety and efficacy of radiofrequency (RF) ablation of ventricular tachycardia associated with ischemic cardiomyopathy performed with…
- Trial name
- VISABL-VT (NCT05543798)
- Testing
- Vision-MR Ablation Catheter 2.0
- Where
- 3 sites in Germany, Netherlands
- Volunteers
- 64 people
- Sponsor
- Imricor Medical Systems
Ventricular Tachycardia (VT)
VT ART Consortium: Radioablation for Ventricular Tachycardia
The overall objective of the study is to evaluate the efficacy and safety of stereotactic radiation therapy in the non invasive ablation of ventricular tachycardia refractory to any other type treatment.
- Trial name
- VT-ART-P (NCT06922214)
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS