Clinical trials: Vertebra; Degeneration
Lumbar Spine Degeneration
Mini-invasive Lumbar Arthrodesis in Ambulatory
Degenerative lumbar pathologies are characterised by functional impairment and the occurrence of severe chronic pain and disability Arthrodesis of the lumbar spine is a common surgery for the treatment of degenerative lumbar…
- Trial name
- ALAMBU (NCT04914728)
- Testing
- mini-invasive lumbar arthrodesis
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Elsan
Degenerative Disc Disease
Pilot Study of rhBMP-2/BCP in Patients With Spinal Degeneration With Instability Requiring Surgical Fusion
This study is designed to generate data relating to patient safety, bone generating activity associated with the use of the rhBMP-2/BCP device as compared to autograft and to evaluate the feasibility of conducting a larger…
- Trial name
- NCT01495234
- Testing
- rhBMP-2/BCP device
- Volunteers
- 15 people
- Sponsor
- Medtronic Spinal and Biologics
Lumbar Spine Degeneration
MOTUS Total Joint Replacement Investigational Device Exemption Study
This study is designed to collect safety and efficacy data on patients who plan to undergo a single-level total joint replacement of the lumbar spine using the MOTUS device (MOTUS Total Joint Replacement procedure) to demonstrate…
- Trial name
- NCT05438719
- Testing
- MOTUS Total Joint Replacement
- Where
- 14 sites in United States
- Volunteers
- 158 people
- Sponsor
- 3Spine
Surgical Wound Infection, Spinal Deformity
Comparison of Antibiotic Protocols in Spine Patients With Postoperative Drains
In spine surgery, postoperative spinal drains are often utilized to prevent fluid buildup around the spinal cord. The purpose of this study is to determine whether postoperative antibiotic treatment continued for the duration of…
- Conditions
- Surgical Wound Infection, Spinal Deformity, Spinal Degeneration
- Trial name
- NCT01608854
- Testing
- Antibiotic Protocol
- Where
- United States
- Volunteers
- 539 people
- Sponsor
- NYU Langone Health
Low Back Pain, Disc Disease
Bone Marrow Concentrate (BMC) Injection in Intervertebral Discs
Intradiscal delivery of bone marrow concentrate (BMC) into discs, facet, epidural space, and sacroiliac joints
- Conditions
- Low Back Pain, Disc Disease, Disc Degeneration, Arthropathy Vertebrae
- Trial name
- NCT04559295
- Testing
- Bone Marrow Concentrate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stem Cures
Degenerative Disc Disease, Cervical Spine Degeneration
Stand-Alone Cage Verus Anterior Plating for Anterior Cervical Discectomy and Fusion.
The purpose of this study is to compare the clinical results between two different techniques for ACDF: 1. Stand-alone ACDF, which means the placement of an interbody device (cage) without anterior fixation or plating; 2.
- Trial name
- NCT03312192
- Testing
- Interbody Cage, Interbody Cage and Anterior Plating
- Where
- United States
- Sponsor
- Rush University Medical Center
Spinal Tumor, Traumatic Injury of Spine
Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery
The research project is testing whether in screw insertion of spine surgery using "Anatase" Spine Surgery Navigation System is at least as safe and accurate as using O-arm assisted spine surgery- Medtronic Stealthstation S7…
- Conditions
- Spinal Tumor, Traumatic Injury of Spine, Degenerative Spine Disease
- Trial name
- NCT04578691
- Testing
- "Anatase" Spine Surgery Navigation System, Medtronic Stealthstation S7 Treatment Guidance System
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Lumbar Spine Degeneration
rhBMP-2 Versus Vivigen in Lumbar Fusion Procedures
This study is aimed at comparing the overall efficacy (clinical and radiographic) of Vivigen, a novel cellular allograft product, and rhBMP-2 when utilized in lumbar fusion procedures.
- Trial name
- NCT03527966
- Testing
- 5cc Vivigen and local autograft, Small kit rhBMP-2 with local autograft
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Hyperalgesia
Local Anesthetic Infiltration to Prevent Postoperative Pain After Lumbar Surgery
Posterior lumbar arthrodesis causes severe postoperative pain, hampering patients's postoperative reconvalescence especially functional rehabilitation.
- Trial name
- ICALP (NCT00825422)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Vertebral Disc Degenerative Disease
Calculating the Volume of the Paravertebral Space
Volume of the paravertebral spaces of the tharic and lumbar regions will be measured.
- Trial name
- NCT05414604
- Testing
- 3D spine CT
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kocaeli University
Pressure Ulcer, Sleep Disorder
Adaptation of Mattresses Made With Different Materials to Personal Anthropometry Values and Body Postures
Sleep disorders affect 40% of the adult population each year and are often associated with morbidity and mortality (Kripke et al., 2002; F.-Z. Low et al., 2017).
- Conditions
- Pressure Ulcer, Sleep Disorder, Spine Degeneration, Body Structure, Altered From Its Original Anatomical Structure
- Trial name
- NCT05486039
- Testing
- Changing behaviour
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Lumbar Spine Degeneration
3Spine Lumbar Fusion Real World Evidence Study
This study is designed to collect real world evidence (RWE) safety and efficacy data on patients who plan to undergo a single-level Transforaminal lumbar interbody fusion (TLIF) or Posterior lumbar interbody fusion (PLIF)…
- Trial name
- NCT04823858
- Testing
- Lumbar Interbody Fusion
- Where
- 20 sites in United States
- Volunteers
- 176 people
- Sponsor
- 3Spine
Lumbar Spine Degeneration
Study Using the SpinalStim Device Following Lumbar Fusion Surgery
This study examines the effect of adjunctive use of the SpinalStim bone growth stimulator on lumbar fusion rate in high risk subjects who have had lumbar fusion surgery.
- Trial name
- NCT03176303
- Testing
- SpinalStim
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Orthofix Inc.
Hyperkyphosis, Walking, Difficulty
Walking and Balance Related to Sagittal Spinal Posture Alignment
This study aims to improve understanding of the relationship between spinal alignment and walking and balance in people who have degenerative spinal conditions.
- Conditions
- Hyperkyphosis, Walking, Difficulty, Balance; Distorted, Spinal Disease
- Trial name
- WiSPA (NCT04008459)
- Testing
- Therapeutic exercise class
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- University of Oxford