Clinical trials: Vertebral Fractures
Vertebral Compression Fractures
Vertebroplasty In The Treatment Of Acute Fracture Trial - The VITTA Trial
The VITTA trial is a randomized, controlled, single-blinded, cross-over trial comparing percutaneous vertebroplasty with facet block in patients with acute (<1month) and painful vertebral compression fractures.
- Trial name
- VITTA (NCT02370628)
- Testing
- Percutaneous vertebroplasty, Facet block
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Osteoporosis
Treatment of Childhood Osteoporosis With Alendronate (Fosamax)
Bones grow and stay strong through a continuous process of formation (building) and resorption (break down). When more bone is formed than resorbed, the density (level of calcium) in bone increases and the bones become stronger.
- Trial name
- NCT00001720
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Acromegaly, Osteoporosis Risk
Bone MicroArchitecture in Acromegaly
The investigators will conduct a cross-sectional study of bone density, bone microarchitecture, vertebral fractures and trabecular bone score in 25 patients with acromegaly treated with Pegvisomant, the growth hormone (GH)…
- Trial name
- NCT03225040
- Testing
- Pegvisomant
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Columbia University
Spine Disease, Spinal Fractures
Evaluation of the Safety and Efficacy of Smart Orthopedic Minimally Invasive Surgical Systems for Spinal Surgery
To evaluate the safety and effectiveness of the intelligent orthopedic minimally invasive surgery system developed by Shenzhen Xinjunte Intelligent Medical Equipment Co., Ltd. in spinal surgery.
- Trial name
- NCT04956588
- Testing
- surgical robot, controlled approach
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Degenerative Disc Disease (DDD), Spinal Stenosis
PMCF Study on the Effectiveness and Safety of METROSAN Spinal Systems and BONEGRAFT Filling Materials
This is a prospective, multi-center, observational Post-Market Clinical Follow-Up (PMCF) study designed to collect additional safety and clinical performance data on CE-marked Titania® spinal instrumentation and fusion systems…
- Conditions
- Degenerative Disc Disease (DDD), Spinal Stenosis, Spondylolisthesis, Spinal Deformities
- Trial name
- INFO SPINE (NCT07615491)
- Testing
- Titania® Cervical Interbody Fusion Cage (Titanium), Titania® Cervical Interbody Fusion Cage (PEEK), Titania® Posterior Cervical Stabilization System
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 561 people
- Sponsor
- Metrosan End. ve Elk. Mek. Cihazlar ve Tibbi Malz. San. Tic. Ltd. Co.
Osteoporotic Vertebral Compression Fractures
Tripod-Fix Vertebral Body Augmentation System in Osteoporotic Vertebral Compression Fractures Treatment
This study is to evaluate the safety and effectiveness of the Tripod-Fix with Tecres Mendec® Spine HV System to treat subjects with osteoporotic vertebral compression fractures.
- Trial name
- NCT06261242
- Testing
- Tripod-Fix Vertebral Body Augmentation System (Tripod-Fix)
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Cheng-Kung University Hospital
Osteoporosis, Back Pain
VERTOS-II. Percutaneous Vertebroplasty Versus Conservative Therapy
Percutaneous vertebroplasty is a new procedure for treating painful osteoporotic compression fractures of the spine. Five-thousand out of 12.000 patients (16.000 vertebral fractures/year in the Netherlands) present with sudden…
- Trial name
- NCT00232466
- Testing
- Vertebroplasty
- Where
- 6 sites in Belgium, Netherlands
- Volunteers
- 200 people
- Sponsor
- Clinical Research Office Imaging Division
Low Trauma Non Vertebral Fracture
Study of Current Practice Evaluating the Efficacy of a Mobile Short Message Service (SMS) on Post-fracture Management.
The purpose of the study is to show that the standardized sending of SMS improve the bone mineral density (BMD) screening of patients seen in the Emergency department for low trauma fracture.
- Trial name
- Ostéo-SMS (NCT01915745)
- Testing
- Use of SMS
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 1, Bone Fracture
Prevalence of Vertebral Fractures in Patients With Type 1 Diabetes
Background : Type 1 diabetes is associated with an increased risk of fractures. The mechanisms accounting for this bone fragility are not yet fully understood.
- Conditions
- Diabetes Mellitus, Type 1, Bone Fracture, Bone Health
- Trial name
- DenSiFy (NCT04064437)
- Testing
- Clinical tests, Biochemical tests, DXA scan
- Where
- 2 sites in Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Vertebral Body Fracture
Creation of a Small Cavity Reduces the Rate of Cement Leakage During Vertebral Body Augmentation
Leakage of polymethylmethacrylate (PMMA) is the most common complication during vertebral body augmentation and can lead to serious patient morbidity.
- Trial name
- NCT02557113
- Testing
- Vertebroplasty, Cavuplasty
- Volunteers
- 36 people
- Sponsor
- Mohammad ARAB MOTLAGH
Discectomy, Vertebral Fractures
Comparative Study Between ESPB Versus IV Morphine as Postoperative Analgesia After Spine Surgeries .
Postoperative pain is often severe in patients undergoing lumbar surgery. Due to postoperative pain, patients are unwilling to get out of bed at an early stage, which affects their recovery.
- Trial name
- NCT05350696
- Testing
- Erector Spinae plane block (plain pubivicaine), Intravenous morphine group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Single Level Stable Thoracolumbar Fracture Type AO A3, Multiple Level Stable Thoracolumbar Fracture Type AO A3
Spine FA3 - a Prospective, International, Multicenter Cohort Study on Treatment of of AO A3 Thoracolumbar Fractures
Thoracolumbar fractures are the most common spinal fractures with an average annual incidence between 18 and 30 per 100'000 inhabitants. The majority of these fractures are AO type A3 ("burst fractures").
- Trial name
- FA3 (NCT01751633)
- Testing
- Surgical, Conservative treatment
- Where
- 8 sites in Brazil, Chile and 4 more
- Volunteers
- 38 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Vertebral Fractures
Prevalence of Vertebral Fractures in HIV Infected Patients Older Than 50 Years
Prospective cohort study to determine the prevalence of vertebral fractures in HIV infected patients older than 50 years.
- Trial name
- FractaVIH (NCT02131571)
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Lumbar Vertebral Fracture
Percutaneous Screw Fixation vs. Open Fixation in the Treatment of Thoracolumbar Fractures
In this single-center retrospective study, the investigators will include all patients admitted to Parkland Hospital who underwent surgical fixation of thoracolumbar fractures between the years 2000 and 2017.
- Trial name
- PrecScrew (NCT04495400)
- Testing
- Thoracolumbar Fracture Fixation
- Where
- United States
- Volunteers
- 485 people
- Sponsor
- University of Texas Southwestern Medical Center
Osteoporotic Fracture of Vertebra
Vertebroplasty and Kyphoplasty in Osteoporotic Vertebral Body Fractures.
Vertebral body fractures are a major health care problem in all countries with incidence 1.4%. They are a common cause of severe debilitating pain, with consequent deteriorated quality of life, physical function and psychosocial…
- Trial name
- NCT03682328
- Testing
- vertebroplasty, kyphoplaty
- Volunteers
- 23 people
- Sponsor
- Assiut University
Pathologic Fracture of the Vertebra Due to Osteoporosis
Clinical Evaluation of the Crosstrees Pod™ in the Treatment of Pathologic Fracture of the Vertebral Body (Levels T4 - L5) in Adult Patients
The clinical trial is being conducted to evaluate the performance of the Crosstrees System in reducing pain and decreasing the risk of cement leakage associated with vertebroplasty and kyphoplasty.
- Trial name
- NCT00933036
- Testing
- Crosstrees Pod system for PVA
- Where
- 9 sites in United States
- Volunteers
- 135 people
- Sponsor
- Crosstrees Medical Inc.
Osteoporotic Vertebral Fracture, Prediction Model
Construction and Validation of a Risk Prediction Model for Secondary Vertebral Fracture in Patients With Osteoporotic Vertebral Compression Fractures After Percutaneous Vertebroplasty
"Retrospectively collecting clinical data from post-PVA (Percutaneous Vertebroplasty) patients, recording incidences of secondary vertebral fractures, and conducting statistical analysis to create a risk prediction model for…
- Trial name
- NCT06172179
- Testing
- No interventions
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University