Clinical trials: Vestibular
Vestibular Diseases, Labyrinth Diseases
Evaluation of a Sensory Enrichment Multimodal Device (SEMD) on Physical Therapy Patients With Disequilibrium
Purpose of this study is to determine the efficiency and safety of a Sensory Enrichment Multimodal Device (SEMD) when applied in conjunction with usual care vestibular-balance physical therapy for rehabilitation of patients who…
- Conditions
- Vestibular Diseases, Labyrinth Diseases, Ear Diseases, Otorhinolaryngologic Diseases
- Trial name
- SEMD (NCT01483937)
- Testing
- Usual care physical therapy plus SEMD, Usual care physical therapy only
- Where
- 4 sites in United States
- Volunteers
- 32 people
- Sponsor
- Karen L Atkins
Vestibular Schwannoma
Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma
This trial will evaluate the safety and tolerability of a single unilateral administration of one of three dose levels of AAVAnc80-antiVEGF and will evaluate the Akouos delivery device to safely achieve the intended product…
- Trial name
- NCT06517888
- Testing
- AAVAnc80-antiVEGF via Akouos Delivery Device
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Akouos, Inc.
Post Concussion Syndrome
Effects of Osteopathic Treatment on Vestibular Disturbed Active Post Concussed Individual
The proposed study is a randomized clinical trial with the purpose of determining the efficacy of osteopathic treatment on vestibular symptoms of the post concussed vestibular disturbed athlete as determined by the Dizziness…
- Trial name
- PCS (NCT01962883)
- Testing
- Osteopathic treatment
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Collège d'Études Ostéopathiques
Mild Traumatic Brain Injury, Vestibular Neuropathy
Incremental Velocity Error as a New Treatment in Vestibular Rehabilitation
The objective for this study is to compare outcome measures from vestibular rehabilitation (VPT) delivered in a traditional method against a new device Incremental Velocity Error (IVE) that improves physiologic performance of the…
- Trial name
- INVENT (NCT03846830)
- Testing
- Incremental Velocity Error (IVE), Traditional Vestibular Rehabilitation (VPT)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
Peripheral Vertigo.
Promethazine vs. Lorazepam for Treatment of Vertigo
This study was a prospective, randomized, double-blind, parallel group clinical trial designed to compare the efficacy of intravenous (IV) promethazine and lorazepam for the treatment of peripheral vertigo in Emergency Department…
- Trial name
- NCT01827293
- Testing
- Promethazine, Lorazepam
- Where
- Iran
- Volunteers
- 210 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Menière's Disease
Latanoprost for the Treatment of Menière's Disease
The purpose of the study is to evaluate the dose regimen, efficacy and safety of latanoprost for the treatment of Menière's disease.
- Trial name
- NCT01973114
- Testing
- Latanoprost
- Where
- 12 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Synphora AB
Insomnia, Sleep Disturbance
Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Insomnia
Insomnia is known to be one of the most common health concerns in in the general population and has been associated with several health consequences.
- Trial name
- NCT04452981
- Testing
- VeNS
- Where
- 2 sites in Hong Kong, United Kingdom
- Volunteers
- 153 people
- Sponsor
- Neurovalens Ltd.
Neurofibromatosis 2, Vestibular Schwannoma
Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors
The purpose of this study is to determine if Lapatinib has any effect on tumors found in patients with Neurofibromatosis Type 2 (NF2). NF2 is a condition that mainly affects the skin and nervous system.
- Trial name
- NCT00973739
- Testing
- Lapatinib
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Fibromyalgia, Vestibular Disease
Effectiveness of Vestibular Rehabilitation for Improving Health Status in Patients With Fibromyalgia
The purpose of this study is to analyze the effectiveness of Vestibular Rehabilitation for improving balance and quality of life of patients with Fibromyalgia Syndrome (SFM).
- Conditions
- Fibromyalgia, Vestibular Disease, Postural Balance, Vestibular Rehabilitation
- Trial name
- NCT05300529
- Testing
- Vestibular Rehabilitation Exercises, Conventional Rehabilitation exercises
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- University of Jaén
Persistent Postural Perceptual Dizziness, Vestibular Disease
How do Individuals Respond to a Diagnosis of 3PD
No studies have explored how patients with chronic dizziness react to a diagnosis of Persistent Postural Perceptual Dizziness (3PD) and their beliefs and representations of the diagnostic label.
- Conditions
- Persistent Postural Perceptual Dizziness, Vestibular Disease, Chronic Dizziness
- Trial name
- NCT04260568
- Testing
- Semi-structured interviews
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Obesity, Metabolic Syndrome
Effect of Vestibular Stimulation on Fat Consumption and Energy Expenditure as Assessed Using Indirect Calorimetry
There is an ongoing and worsening problem with obesity in the developed, and much of the developing world. Although it has long been realized that Western diets that are rich in sugar and fat play an important role in this, it…
- Trial name
- NCT03138382
- Testing
- Vestibular Nerve Stimulator
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Vestibular Diseases, Vestibular Disorder
Effectiveness of Vestibular Electrical Stimulation in Vestibular Rehabilitation
This study aimed to evaluate the effectiveness of the vestibular rehabilitation program applied to patients with chronic unilateral vestibular hypofunction and the vestibular electrical stimulation applied to the trapezius…
- Conditions
- Vestibular Diseases, Vestibular Disorder, Vestibular Vertigo
- Trial name
- NCT06563076
- Testing
- Vestibular Rehabilitation, Vestibular Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Ankara City Hospital Bilkent
Reflex, Abnormal, Bilateral Vestibulopathy
Covert Saccade Triggers in Bilateral Vestibular Hypofunction
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia.
- Conditions
- Reflex, Abnormal, Bilateral Vestibulopathy, Healthy Volunteers
- Trial name
- CS-TRIGGER (NCT04268615)
- Testing
- Covert Saccades and Virtual Reality, Actives versus passives Head Impulses, Visually guided saccades
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Allergy
Efficacy and Tolerability of Two Different Administration Routes With SLITonePLUS Birch
Multicentre Phase II trial, comparing two different administration routes of SLITonePLUS Birch in regard to pharmacodynamic efficacy and tolerability.
- Trial name
- NCT01191359
- Testing
- oral immunotherapy
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- ALK-Abelló A/S
Motion Sickness, Seasickness
Galvanic Vestibular Stimulation as a Novel Treatment for Seasickness
subjects with severe seasickness, who failed to habituate to sea conditions after at least six month of active sailing, were enrolled to the single-blind randomized control study.
- Conditions
- Motion Sickness, Seasickness, Habituation, Vestibular Time Constant
- Trial name
- NCT05004818
- Testing
- GVS stimulation coupled with inverse phase rotatory chair stimulation at sinusoidal harmonic acceleration protocol
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Persistent Postural Perceptual Dizziness
The Effect of Virtual Reality (VR) Versus Conventional Vestibular Rehabilitation and Progressive Muscle Relaxation (PMR) to Improve Balance and Stress Among Patients of Persistent Postural Perceptual Dizziness (PPPD).
To compare the effect of virtual reality (VR) versus conventional vestibular rehabilitation and progressive muscle relaxation (PMR) to improve balance and stress among patients of persistent postural perceptual dizziness (PPPD).
- Trial name
- VR (NCT06479408)
- Testing
- progressive muscle relaxation (PMR) technique and vestibular rehabilitation exercises, virtual reality (VR)
- Where
- Pakistan
- Volunteers
- 25 people
- Sponsor
- Shalamar Institute of Health Sciences
Vestibular Hypofunction, Vestibular Assessment
The Effect of Otolith Dysfunction and Its Rehabilitation in Vestibular Diseases
This randomized controlled study compared the clinical and electrophysiological effectiveness of three vestibular rehabilitation approaches in patients with unilateral peripheral vestibular disease accompanied by otolith…
- Conditions
- Vestibular Hypofunction, Vestibular Assessment, Vestibular Exercises, Vestibulopathy
- Trial name
- NCT07606196
- Testing
- Cawthorne-Cooksey Exercises, 2D Visual Habituation, 3D/Virtual Reality Visual Habituation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Medipol University
Motion Sickness, Space, Visually Induced Motion Sickness
Virtual Reality in the Rehabilitation of Visually Induced Motion Sickness
In recent years, rapidly advancing virtual reality (VR) technology has been widely used in many fields, from education to health and from entertainment to therapeutic applications, by creating interactive and highly immersive…
- Conditions
- Motion Sickness, Space, Visually Induced Motion Sickness, Vestibular Rehabilitation in MS
- Trial name
- VIMS (NCT07318142)
- Testing
- The effects of virtual reality exposure were assessed using posturography.
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Vestibular Disorder
Vestibular Rehabilitation for Unsteadiness After Intratympanic Gentamicin in Patients With Meniere's Disease
To investigate the efficacy of vestibular rehabilitation treatment on unsteadiness after intratympanic gentamicin in patients with Meniere's disease.
- Trial name
- NCT06143462
- Testing
- Usual care, Health Education, vestibular rehabilitation
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Vestibular Schwannoma, Unilateral Vestibular Deficit
Mapping of Vestibular Centers Activation Using fMRI in Patients With Vestibular Schwannoma
The goal of this clinical trial is to visualize the possible activation of vestibular centers in the brain using in patiens with unilateral vestibular damage, specifically in patients after vestibular schwannoma surgery.
- Conditions
- Vestibular Schwannoma, Unilateral Vestibular Deficit, Healthy
- Trial name
- NCT07130851
- Testing
- vestibular schwannoma resection
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marketa Bonaventurova