Clinical trials: Vestibular Disease
Vestibular Diseases
Virtual Reality in Children With and Without Vestibular Deficits
Vestibular information is important in establishing a child's static and dynamic postural control. Any vestibular deficit can have major consequences on development, spatial cognition and quality of life.
- Trial name
- ReViCHILD (NCT04791748)
- Testing
- Vestibular tests, Virtual reality
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Brain Injuries, Disorder of Consciousness
Verticalization Robotic Exoskeleton DoC
Mobilization, specifically verticalization, has been shown to play a role in enhancing consciousness. Vestibular stimulation has the potential to influence the neural substrate of consciousness, but this modality has not been…
- Trial name
- NCT04833543
- Testing
- Robotic Mobility Device (REX), Tilt Table
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Memorial Hermann Health System
Vestibular Disease, Vestibular Dysfunction
Four Ways to Be Dizzy: When Physiology Fails to Explain Disability Insights From the UVIS International Survey
The aim of this international study is to better understand how vestibular disorders affect daily life, including physical balance, vision and movement tolerance, emotional wellbeing, and cognitive functioning.
- Trial name
- UVIS (NCT07297355)
- Where
- 3 sites in United States, Belgium and 1 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Dizziness, Vertigo
Trental for the Treatment of Vertigo/Dizziness/Imbalance
Imbalance, dizziness and vertigo as a result of problems in the inner ear (vestibular dysfunction) are becoming increasingly more prevalent in Americans 40 years of age and older.
- Trial name
- NCT02592863
- Testing
- Pentoxifylline
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Missouri-Columbia
Meniere Disease, Allergic Rhinitis
Repurposed Use of Allergic Rhinitis and Allergic Asthma Drug to Reduce Vertigo and Hearing Loss in Meniere's Disease
The purpose of this study is to evaluate a previously FDA-approved medication that is known to help with allergy symptoms to see if it can decrease symptoms in patients with Meniere's Disease.
- Conditions
- Meniere Disease, Allergic Rhinitis, Vertigo
- Trial name
- NCT04815187
- Testing
- Montelukast
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- House Ear Institute
Vestibulocochlear Nerve Diseases, Vestibular Disorder
Vestibular Balance Therapy Intervention for Children
The goal of this within groups clinical trial is to determine the feasibility of a home-based vestibular balance therapy program for children with vestibular hypofunction.
- Conditions
- Vestibulocochlear Nerve Diseases, Vestibular Disorder, Bilateral Vestibular Loss
- Trial name
- VBT-C (NCT05741515)
- Testing
- Vestibular Balance Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Alabama at Birmingham
Vertigo, Peripheral
The Effect of Pinhole Glasses on Vestibular Electrical Stimulation
Balance is the ability to control and maintain the body's center of gravity within the support area. One of the important causes of imbalance is right or left sided unilateral vestibular hypofunction.
- Trial name
- NCT05516017
- Testing
- Vestibular Electrical Stimulator and Pinhole Glasses, Vestibular Electrical Stimulator
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Simulation, Dizziness
Virtual Patient Education From Real Cases
Misdiagnosis of neurological conditions is common in healthcare settings, sometimes with devastating consequences. Most diagnostic errors result from failures in bedside diagnostic reasoning.
- Conditions
- Simulation, Dizziness, Vertigo, Stroke
- Trial name
- ViPER (NCT04553640)
- Testing
- Group A/Intervention Curriculum, Group B/Control Curriculum
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Vestibulodynia (VBD) From at Least 6 Months
Ultrasound Evaluation and Vestibular Perception Thresholds Changes in Women Affected by Vestibulodynia (VBD) After One Cycle of Pixel CO2-Alma Fractionated Laser
Vestibulodynia (VBD), term revised by Consensus Terminology and Classification of Persistent Vulvar Pain and Vulvodynia in 2015, is a vulvar pain of at least 3 months' duration, without clear identifiable cause and localized at…
- Trial name
- NCT05156489
- Testing
- Fractionated Laser (Pixel CO2-Alma)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Filippo Murina
Vertigo
The Head Impulse Test in the Screening of Vestibular Function
The alternate binaural bithermal caloric test (ABBT) is a well established examination in the evaluation of the dizzy patient. ABBT is useful in detecting the side of peripheral vestibulopathy by stimulating each ear separately…
- Trial name
- NCT01426932
- Testing
- Video recording of Head Impulse Test
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Vestibular Disorder
Concurrent Vestibular Activation and Postural Training Using Virtual Reality
Postural instability is a common symptom of vestibular dysfunction that impacts a person's day-to-day activities. Vestibular rehabilitation is effective in decreasing dizziness, visual symptoms and improving postural control…
- Trial name
- VR-HS-WST (NCT05942781)
- Testing
- Vestibular training using VR followed by Control, Control followed by Vestibular training using VR
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Clarkson University
Autism Spectrum Disorder, Vestibular Hypofunction
Effect of Cawthorne Cooksey Exercises on Balance in Autistic Children With Vestibular Hypofunction.
The objective of the study is to determine the effects of cawthorne cooksey exercises on balance in autistic children with vestibular hypofunction.
- Trial name
- ASD (NCT07061119)
- Testing
- Conventional treatment, cawthorne cooksey exercises
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Provoked Vestibulodynia, Secondary Provoked Vestibulodynia
Topical Ketotifen 0.25% for Secondary Vestibulodynia
This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled trial evaluating the safety and efficacy of topical ketotifen fumarate 0.25% cream in adult women with secondary provoked vestibulodynia (PVD).
- Conditions
- Provoked Vestibulodynia, Secondary Provoked Vestibulodynia, Vulvodynia, Vulvary Pain Disorders
- Trial name
- NCT07257029
- Testing
- Ketotifen Fumarate 0.25% Cream
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Center for Vulvovaginal Disorders
Nystagmus, Dizziness
Effects of Cervical and Oculomotor Exercises in Young Adults With Benign Paroxysmal Positional Vertigo
Benign paroxysmal positional vertigo (BPPV) is the most common type of dizziness disorder in the community.Its cardinal symptoms include vertigo which is induced by change in position of head, turning over in bed, looking up…
- Trial name
- NCT07587528
- Testing
- Occulomotor exercises, Cervical Exercises
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Foundation University Islamabad
Vestibular Schwannoma
Role of ChatGPT in Vestibular Schwannoma Management
Previous studies have demonstrated that patients frequently undergo significant decision conflict regarding major medical decisions in otolaryngology. There lack validated tools available for decision support for patients.
- Trial name
- NCT06163664
- Testing
- Use of chatGPT for 1 week
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southern California
Oroantral Communication, Acute Oroantral Communication
Acute Oroantral Communication Closure: Resorbable Collagen Membrane vs. Buccal Advancement Flap Outcomes
Oroantral communication (OAC) is an abnormal opening between the oral cavity and the maxillary sinus that may occur after extraction of posterior maxillary teeth.
- Conditions
- Oroantral Communication, Acute Oroantral Communication, Oroantral Fistula, Post-extraction Maxillary Sinus Communication
- Trial name
- AOC (NCT07476664)
- Testing
- Resorbable collagen membrane OAC closure, Buccal advancement flap OAC closure
- Where
- Poland
- Volunteers
- 24 people
- Sponsor
- Medical University of Silesia
Vestibular Diseases
Transcutaneous Auricular Vagus Nerve Stimulation on Dizziness & Balance in Elderly Population
The objective of the study is to determine the effects of transcutaneous auricular vagus nerve stimulation on dizziness and balance on elderly population with unilateral vestibular hypofunction.
- Trial name
- NCT06303271
- Testing
- Vagus Nerve Stimulation (VNS) and Caw Thorne Cooksey, Caw Thorne Cooksey
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Vestibular Schwannoma, Acoustic Neuroma
Study of Aspirin in Patients With Vestibular Schwannoma
This is a phase II prospective, randomized, double-blind, longitudinal study evaluating whether the administration of aspirin can delay or slow tumor growth and maintain or improve hearing in VS patients.
- Conditions
- Vestibular Schwannoma, Acoustic Neuroma, Neurofibromatosis 2
- Trial name
- NCT03079999
- Testing
- Aspirin
- Where
- 5 sites in United States
- Volunteers
- 97 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Substance Use Disorders
Investigating the Efficacy of Caloric Vestibular Stimulation in the Treatment of Substance Use Disorders
The purpose of this study is to determine efficacy and effect of CVS (caloric vestibular stimulation)
- Trial name
- NCT03652311
- Testing
- ThermoNeuroModulation TNM Device
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Inner Ear Disease, Equilibrium; Disorder, Labyrinth
Unilateral Peripheral Vestibular Dysfunction: Reeducation and Spatial Orientation.
Motor control includes postural control and voluntary movement. For an optimal motor control it is necessary that brain integrates vestibular, visual and somatosensorial inputs properly, in a nonlinear way.
- Conditions
- Inner Ear Disease, Equilibrium; Disorder, Labyrinth, Spatial Navigation
- Trial name
- NCT03171181
- Testing
- Vestibular reeducation
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza