Clinical trials: Veteran
Falls
Targeting the Hip Abductors to Reduce Falls in Older Veterans Through A Virtual Multimodal Balance Intervention
Falls are a major health concern and a leading cause of injurious death and non-fatal injuries in older Veterans who are at greater risk for falls than non-Veterans.
- Trial name
- Virtual MMBI (NCT07109466)
- Testing
- Mulit-modality Balance Intervention, Gerofit
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder, Major Depressive Disorder
Adjunctive Pregnenolone in Post-Traumatic Stress Disorder (PTSD) and Depression in Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans
This study will be an 8-week randomized, placebo-controlled clinical trial of pregnenolone administered adjunctively to treatment as usual in PTSD and depression in OEF/OIF Veterans.
- Trial name
- NCT00993629
- Testing
- pregnenolone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Burn Pit Exposure
Tele-Exercise for MERP
During Operations Desert Shield and Desert Storm, Veterans in combat were exposed to a variety of airborne hazards, including oil well fire smoke, emissions from burn pits, and other substances associated with negative health…
- Trial name
- TEMPO (NCT07018466)
- Testing
- Tele-exercise, Standard of Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Moderate Cognitive Impairment, Traumatic Brain Injury
Foundations in Developing Precision Cognitive Restoration
This pilot study tests the merits of a unique research approach, transdiagnostic sampling. For Veterans with similar levels of cognitive impairments cause by different types of brain injuries (stroke or traumatic brain injury)…
- Conditions
- Moderate Cognitive Impairment, Traumatic Brain Injury, Stroke
- Trial name
- NCT05117502
- Testing
- intermittent Theta Burst Stimulation
- Where
- United States
- Sponsor
- VA Office of Research and Development
Chronic Pain, PTSD - Post Traumatic Stress Disorder
Virtual Reality and Cranial Nerve Non-invasive Neuromodulation to Improve Quality of Life for Veterans
Veterans in Canada are twice as likely as the general population to experience chronic pain. This pain is often linked to post-traumatic stress disorder (PTSD), and both have a major impact on their quality of life.
- Conditions
- Chronic Pain, PTSD - Post Traumatic Stress Disorder, Quality of Life (QOL)
- Trial name
- VR & CN-NINM (NCT07137845)
- Testing
- Virtual reality, Cranial nerve non-invasive neuromodulation (CN-NINM)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Université de Sherbrooke
Stress Disorders, Post-Traumatic
An Immersion Intervention for Symptoms of PTSD in Student Veterans
This study will explore the physical and psychological effects of warm water immersion to the chest on student Veterans who experience symptoms of Post-Traumatic Stress Disorder (PTSD) and may also have depression, anxiety and…
- Trial name
- NCT05309031
- Testing
- Water Immersion
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Nevada, Las Vegas
Tobacco Smoking, Alcohol-Related Disorders
Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease
Many Veterans who have chronic conditions like cardiovascular disease or diabetes smoke or drink too much alcohol, which can worsen the condition.
- Trial name
- MINDSET (NCT07039175)
- Testing
- MINDSET, Usual Care
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- VA Office of Research and Development
Aging, Mobility Limitations
Life 2: Improving Fitness and Function in Elders
The purpose of this study is to determine whether a 12-month physical activity counseling program, compared to usual care, improves physical performance in a sample of older veterans.
- Trial name
- Project LIFE (NCT00435188)
- Testing
- Multi-component physical activity counseling program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injury (=3 Years), Sublesional Bone Loss Secondary to SCI
Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI
Treatment for sublesional bone loss (osteoporosis) in persons with chronic, motor-complete spinal cord injury (SCI) has been limited and unsuccessful to date.
- Trial name
- Chronic Romo (NCT04232657)
- Testing
- Romosozumab, Denosumab
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury
Improving Work Outcomes for Veterans With Traumatic Brain Injury
The 12-month study will investigate a cognitive training augmentation of supported employment to improve cognitive performance and work outcomes, which are expected to result in improved quality of life and community integration…
- Trial name
- NCT00704067
- Testing
- Supported employment plus cognitive training, Enhanced supported employment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- United States Department of Defense
Urothelial Carcinoma
Detection and Risk Stratification in Veterans Presenting With Microscopic Hematuria
It is currently debated whether the use of invasive standard of care procedures, such as cystoscopy, a procedure which involves inserting a thin camera, called a cystoscope, into the bladder to look for signs of disease, is…
- Trial name
- microDRIVE (NCT05889195)
- Testing
- Cxbladder urine test
- Where
- 3 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Pacific Edge Limited
Hypertension, Obesity
A Randomized Trial of Behaviorally Designed Gamification and Social Incentives to Increase Physical Activity Among Overweight and Obese Veterans
Despite the many associated health benefits, more than half of Veterans do not achieve enough regular physical activity. The investigators' prior work has demonstrated that gamification, a method commonly used for health…
- Trial name
- STEP 4 Vets (NCT05554601)
- Testing
- gamification with collaboration, gamification with competition
- Where
- United States
- Volunteers
- 725 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Hypogonadism, Aging
Long-term Lifestyle Change and Testosterone Replacement
Older hypogonadal obese veterans previously participated in a 6 month lifestyle change (diet-induced weight loss and exercise) study with or without testosterone replacement therapy before being followed for the following year at…
- Conditions
- Hypogonadism, Aging, Overweight and Obesity
- Trial name
- LITE (NCT03256292)
- Testing
- Testosterone replacement, lifestyle
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Baylor College of Medicine
Spinal Cord Injury
Epidemiology and Cost of Falls in Veterans With a Spinal Cord Injury
Brief Summary Detailed Description Background: A multitude of risk factors for falling has been reported for the elderly, however many of these risk factors are not applicable to persons with a spinal cord injury, who use a…
- Trial name
- NCT00119522
- Where
- 3 sites in United States
- Volunteers
- 702 people
- Sponsor
- US Department of Veterans Affairs
Other Drug Substance Abuse
Iwin: Individual Well-Being Navigator
The overarching objective of this proposal is to conduct a randomized trial to evaluate the effectiveness of the Individual Well-Being Navigator (Iwin) mobile application, a substance abuse prevention and well-being enhancement…
- Trial name
- NCT02823535
- Testing
- Iwin: Individual Well-Being Navigator
- Where
- 4 sites in United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Pro-Change Behavior Systems
Posttraumatic Stress Disorder (PTSD)
Project Remission: Maximizing Outcomes With Intensive Treatments for Combat-Related PTSD
The study compares two intensive outpatient behavioral programs (Massed Prolonged Exposure versus Intensive Outpatient Prolonged Exposure) for the treatment of posttraumatic stress disorder (PTSD) in post-9/11 active duty service…
- Trial name
- NCT03529435
- Testing
- Massed Prolonged Exposure, Intensive Outpatient Prolonged Exposure
- Where
- 4 sites in United States
- Volunteers
- 234 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Knee Osteoarthritis
Non-Surgical Management of Knee Osteoarthritis in the Military Health System (MHS)
This study will compare two different treatment approaches for the management of knee osteoarthritis (OA). All subjects will receive a standardized approach consistent with the core set of recommendation from the Department of…
- Trial name
- NCT03747393
- Testing
- DoD/VA CPG Core Set + PT, DoD/VA CPG Core Set
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Brooke Army Medical Center
Multimorbidity, Physical Deconditioning
Multicomponent Telerehabilitation to Engage Veterans in Effective Self-Management of Complex Health Conditions
Medically complex older Veterans are at greater risk for progressive declines in physical function, lower quality of life, and increasing care needs.
- Trial name
- NCT06288438
- Testing
- Motivational Interviewing Techniques, Physical Therapy Interventions, Education
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury, Hopelessness
Window to Hope-Evaluating a Psychological Treatment for Hopelessness Among Veterans With Traumatic Brain Injury
The purpose of this project is to provide further evidence regarding a groundbreaking psychological treatment for suicide prevention in individuals with moderate to severe traumatic brain injury (TBI), Window to Hope (WtoH).
- Conditions
- Traumatic Brain Injury, Hopelessness, Suicide
- Trial name
- WtoH (NCT01691378)
- Testing
- Window to Hope, Waitlist Control
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Lisa Brenner
Pelvic Pain, Distress, Emotional
Pelvic Pain Education and Skills Training for Women Veterans
The goals of this pilot randomized clinical trial are three-fold: 1) to test the feasibility of conducting a larger randomized trial using a brief Acceptance and Commitment Training (ACT) group intervention for women veterans…
- Trial name
- NCT06062043
- Testing
- Brief ACT with CPP Education Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine