Clinical trials: Veteran, open to volunteers
PTSD - Post Traumatic Stress Disorder
Transcranial Magnetic Stimulation in Veterans With PTSD
With this research investigators hope to begin to understand how rTMS can improve posttraumatic stress disorder (PTSD) symptoms.
- Trial name
- NCT07336251
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- White River Junction Veterans Affairs Medical Center
Functional Impairment, Frailty
A Partnered Evaluation to Improve the Identification and Management of Functional Impairment and Frailty Among Older Veterans in Primary Care Settings
Maintaining functional status, or the ability to perform daily activities, is central to older adults' quality of life, health, and ability to remain independent.
- Trial name
- NCT06404970
- Testing
- Screening intervention, Standard bundle of implementation strategies, Enhanced bundle of implementation strategies
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- VA Office of Research and Development
Aging, Fall Risk
Implementation of Routine Walking Speed Measurements in Older Veterans
Walking speed is a powerful predictor of mortality and adverse health consequences (e.g. fall or hospitalization) in older adults.
- Conditions
- Aging, Fall Risk, Mobility Limitation
- Trial name
- NCT07513805
- Testing
- Usual Care, FASTER
- Where
- United States
- Volunteers
- 10,500 people
- Sponsor
- VA Office of Research and Development
Social Anxiety Disorder
Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety Disorder
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective treatment for individuals with depressive/anxiety disorders.
- Trial name
- NCT05858346
- Testing
- Transdiagnostic Behavior Therapy, Cognitive Behavioral Therapy for Social Anxiety Disorder
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- VA Office of Research and Development
Psychosocial Functioning, Stress Disorders, Post-Traumatic
A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms
Posttraumatic stress disorder (PTSD) and depression are the two most common mental health conditions among Veterans. When Veterans experience both, there is a negative impact on their functioning, making it difficult to function…
- Conditions
- Psychosocial Functioning, Stress Disorders, Post-Traumatic, Depressive Disorder, Major
- Trial name
- NCT06689787
- Testing
- Self-Guided STAIR Coach with Real-Time Assessment, Real-Time Assessment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Diagnoses of Depression, Anxiety
Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0)
The proposed project is a randomized controlled trial that seeks to test the effectiveness of a peer-facilitated, patient navigation program to improve mental healthcare experiences and outcomes for under-supported Veterans from…
- Conditions
- Diagnoses of Depression, Anxiety, PTSD
- Trial name
- PARTNER-MH (NCT07645274)
- Testing
- PARTNER-MH, Educational Brochure
- Where
- 2 sites in United States
- Volunteers
- 268 people
- Sponsor
- VA Office of Research and Development
Chronic Pain
Assessing the Efficacy of an Acceptance-Based Digital Intervention for Veterans With Chronic Pain
Pain has been identified as among the most frequent presenting medical complaints, in particular within primary care for Veterans.
- Trial name
- VACT-CP (NCT06058624)
- Testing
- Veteran ACT for Chronic Pain (VACT-CP), Online Pain School
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Concussion, Mild Traumatic Brain Injury, Brain Injury
Expanding Access to mTBI Treatment for Veterans and Service Members With Co-occurring Substance Use
The purpose of this research is to determine whether military veterans and service members with mild traumatic brain injury with and without co-occurring substance use can complete and benefit from integrated interdisciplinary…
- Conditions
- Concussion, Mild Traumatic Brain Injury, Brain Injury, Traumatic Brain Injury, Substance Use
- Trial name
- ExpandAccess (NCT06620900)
- Testing
- Integrated Model of Care
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Shepherd Center, Atlanta GA
Chronic Pain
Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention - UH3
The goal of the RAMP mind-body program is to provide Veterans with information and tools that can help them manage their pain. The program explores the important connection between our bodies and minds, and how to use this…
- Trial name
- RAMP (NCT07541599)
- Testing
- RAMP Program
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Schizophrenia, Psychosis
Enhancing Rehabilitation for Veterans With Serious Mental Illness
This study addresses the critical need for innovative therapeutic interventions in Veterans with serious mental illnesses (SMI) receiving care in VA Psychosocial Rehabilitation and Recovery Centers (PRRCs).
- Conditions
- Schizophrenia, Psychosis, Serious Mental Illness, PTSD
- Trial name
- NCT06586164
- Testing
- Targeted Cognitive Training
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Tobacco Use Disorder
Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness
Seventy to eighty percent of Veterans experiencing homelessness (VEH) smoke, which is four times the rate of the U.S. population and 2.5 times higher than among impoverished Americans.
- Trial name
- New HART (NCT07714200)
- Testing
- Cognitive Behavioral Therapy for Smoking Cessation, Nicotine Replacement Therapy, Bupropion
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Chronic Low-back Pain (cLBP)
Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain
Chronic low back pain (CLBP) is a major health challenge in Canada, leading to substantial disability and socioeconomic burden, particularly among Veterans. In military Veterans, LBP is the most common chronic pain condition.
- Trial name
- NCT06999772
- Testing
- Active rTMS, Psychologically-informed physiotherapy (PiP), Usual physiotherapy
- Where
- 2 sites in Canada
- Volunteers
- 96 people
- Sponsor
- Laval University
Posttraumatic Headache
Multisite Advancement of Research on Chronic Posttraumatic Headache
Posttraumatic headache (PTH) is a common and highly disabling consequence of traumatic brain injury (TBI) in U.S. military service members and veterans.
- Trial name
- NCT05620719
- Testing
- Cognitive Behavioral Therapy for Posttraumatic Headache, Treatment as Usual, Telemedicine-based Cognitive Behavioral Therapy (TCBT)
- Where
- 8 sites in United States
- Volunteers
- 525 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Substance Use Disorder
Personalized Approach to Healthy Use and Recovery (PATH) Trial
An important part of substance use treatment for many people is learning what triggers their substance use and urges, and how they can better manage those triggers.
- Trial name
- PATH (NCT06580457)
- Testing
- Personal Causal Model + Personalized Feedback
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- VA Office of Research and Development
COPD, Chronic Musculoskeletal Pain
The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
Persons with COPD benefit from being physically active, but they are often limited by chronic musculoskeletal pain. This project will determine whether a non-pharmacologic, integrated, technology-mediated walking and Tai Chi…
- Trial name
- WATCH for Pain (NCT05701982)
- Testing
- Every Step Counts-Tai Chi, Usual Care
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Parkinson's Disease
Non-invasive VNS for Parkinson's Gait
More than 110,000 US Veterans living with Parkinson's disease (PD) currently receive PD-related care and services from the VA. Fall prevention is a priority for Veterans living PD.
- Trial name
- NCT06562569
- Testing
- non-invasive cervical vagal nerve stimulation ncVNS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Post-Traumatic Stress Disorder (PTSD)
Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD
Leveraging veterans' intimate relationships during treatment for posttraumatic stress disorder (PTSD) has the potential to concurrently improve PTSD symptoms and relationship quality.
- Trial name
- CBCT-OT RCT (NCT06194851)
- Testing
- Oxytocin nasal spray, Saline nasal spray, Brief Cognitive-Behavioral Conjoint Therapy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Military Transition, Community Reintegration
Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans
The objective of this study is to develop and pilot a program designed to improve mental health outcomes and reduce suicide risk during the transition from military to civilian life.
- Conditions
- Military Transition, Community Reintegration, Mental Health, Suicidal Ideation
- Trial name
- NCT06778278
- Testing
- Transition Health and Resilience through Valued Experiences (THRiVE) Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- RTI International
PTSD, Post Traumatic Stress Disorder
Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery
The overall strategy is to recruit veterans with PTSD who report minimal current cannabis use but are interested in or considering therapeutic cannabis to manage mental health symptoms (anxiety, depression, PTSD and/or…
- Conditions
- PTSD, Post Traumatic Stress Disorder, Suicide, Cannabis Use
- Trial name
- CAPER (NCT06222268)
- Testing
- Cannabidiol (CBD) only, Delta-9-tetrahydrocannabinol (THC) only, THC:CBD 1:1
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Leslie Lundahl
Post Traumatic Stress Disorder
Cognitive Processing Therapy for Posttraumatic Stress Disorder and Co-occurring Lived Experience Stress
Populations facing health disparities include groups with significantly higher rates of posttraumatic stress disorder than the general population who frequently experience lived experience stress, which may complicate…
- Trial name
- NCT07714083
- Testing
- Standard CPT, CPT-LEAP
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Boston University