Clinical trials: Viral Load
SARS-CoV-2
ACE2 Chewing Gum on SARS-CoV-2 Viral Load (COVID 19)
A randomized double-blind, placebo controlled clinical trial of the safety, tolerability, and antiviral activity of angiotensin-converting enzyme 2 (ACE2) chewing gum over a 3-day period in non-hospitalized subjects with Severe…
- Trial name
- NCT05433181
- Testing
- ACE2 Chewing Gum
- Where
- United States
- Sponsor
- University of Pennsylvania
Chronic Hepatitis B, Antiviral Treatment
Roll-over After 3-year Trial for Tenofovir in Mild Chronic Hepatitis B
This open-label study is an roll-over extension of a randomized trial "Efficacy of Tenofovir Disoproxil Fumarate in Chronic Hepatitis B Patients with High Viral Load but Slight Aminotransferase Elevation" (NCT01522625).
- Trial name
- NCT02463019
- Testing
- Tenofovir Disoproxil Fumarate
- Volunteers
- 160 people
- Sponsor
- E-DA Hospital
Cognitive Disorders, HIV Infections
HIV Levels in Cerebrospinal Fluid and Brain Function in Patients Receiving Anti-HIV Drugs
The purpose of this study is to see whether anti-HIV drugs that reduce HIV in the blood also reduce HIV in the cerebrospinal fluid (CSF). CSF is the fluid found around the brain and spinal cord.
- Trial name
- NCT00001103
- Where
- 26 sites in United States, Puerto Rico
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19, Coronavirus
Efficacy of Mouthwashes in Reducing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Viral Load in the Saliva
This is a single-blind, parallel-group, randomized pilot study designed to evaluate and compare the efficacy of 3 different mouthwashes containing 0.2% Chlorhexidine digluconate, 1.5% Hydroxide peroxide or Cetylpyridinium…
- Trial name
- COVID-19 (NCT04723446)
- Testing
- Corsodyl® Alcohol free -0.2 % Chlorhexidine digluconate, Colgate Peroxyl® -1.5% Hydrogen peroxide, Oral-B® Gum & Enamel Care -Cetylpyridinium chloride
- Where
- 2 sites in United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
HIV-1-infection
Alternative Viral Load Tests During Start of Antiretroviral Therapy
A pilot study of alternative viral load testing with samples collected in the clinic and at home compared to traditional viral load monitoring in participants engaged in HIV care.
- Trial name
- NCT05418790
- Testing
- TASSO device
- Sponsor
- Luis Montaner
HIV Infections
A Study to Evaluate the Effects of Different Methods of Birth Control on the Drug Actions of Zidovudine (an Anti-HIV Drug) in HIV-Positive Women and to Compare Zidovudine Metabolism in Men and Women
The purpose of this study is to look at the effects of different methods of birth control (oral and injectable) on how the body absorbs, makes available, and removes zidovudine (ZDV).
- Trial name
- NCT00000897
- Testing
- Zidovudine
- Where
- 6 sites in United States
- Volunteers
- 42 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
2019 Novel Coronavirus Infection
Povidone Iodine Nasal Irrigation and Gargling to Reduce Viral Load in Asymptomatic Patients With COVID-19
The emergence of a novel coronavirus(SARS-CoV-2) in late 2019 has resulted in a global epidemic of the infectious condition COVID-19.
- Trial name
- SMART-CORE (NCT05375773)
- Testing
- PVP-I Nasal Irrigation and gargling
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Ruijin Hospital
HIV Infections
The Effects of Anti-HIV Drugs in HIV-Infected Patients Who Do Not Have AIDS
Immunopathogenesis objectives: To compare and quantitatively determine HIV burden and HIV replication in peripheral blood (PB) and lymphoid tissue (LT).
- Trial name
- NCT00001024
- Testing
- Zidovudine, Didanosine
- Where
- 8 sites in United States
- Volunteers
- 32 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19
COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Camostat Sub-Protocol
The overall objective of this study is to efficiently evaluate the clinical efficacy and safety of different investigational therapeutics among adults who have COVID-19 but are not yet sick enough to require hospitalization.
- Trial name
- COPPS (NCT04662073)
- Testing
- Camostat
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Stanford University