Clinical trials: Viral Pneumonia
Severe Sepsis
Symphony IL-6 Study in Patients at Risk of Severe Sepsis
Symphony IL-6 is a device that quantitates human IL-6 by fluorescence enzyme immunoassay (FEIA) from whole-blood specimens. Use of Symphony IL- 6 removes the need for plasma separation before testing.
- Trial name
- NCT05665153
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Bluejay Diagnostics, Inc.
COVID-19, SARS-COV-2 Infection
A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age
This study is designed to find out how well the COVID-19 vaccine protects people 50 to 64, who don't have any serious health problems, compared to a group that receives a vaccine that doesn't contain an ingredient to protect…
- Trial name
- NCT07300839
- Testing
- BNT162b2 Vaccine
- Where
- 196 sites in United States
- Volunteers
- 5,240 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
SARS-CoV-2
A Study of Secutrelvir in Participants With Coronavirus Disease 2019 (COVID-19) Who Are at High Risk for Progression to Severe Disease
The primary purpose of this study is to evaluate the efficacy and safety of secutrelvir in symptomatic nonhospitalized adult and adolescent participants with COVID-19 who are at high risk for progression to severe disease.
- Trial name
- NCT07743580
- Testing
- Secutrelvir
- Where
- 51 sites in United States, Bulgaria and 1 more
- Volunteers
- 2,000 people
- Sponsor
- Shionogi
Cardiac Arrest, Needle Stick
Needle Stick Injuries in Emergency Medical Service Practice
During the pandemic era, medical personnel should wear full protective suits. However, they limit the performance of medical procedures. One of the main questions is whether to use double gloves.
- Conditions
- Cardiac Arrest, Needle Stick, Injuries, Glowe
- Trial name
- NCT04363788
- Testing
- double gloves
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Lazarski University
COVID-19, Pneumonia
Efficacy and Safety of Jaktinib in Participants With Severe Novel Coronavirus Pneumonia(COVID-19)
This study adopts a randomized, double-blind, placebo parallel control design, and is expected to include 168 eligible patients with severe novel coronavirus pneumonia.
- Trial name
- COVID-19 (NCT05702788)
- Testing
- Jaktinib hydrochloride tablets
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
COVID-19, Vaccines
Immunogenicity Evaluation of Omicron Variant-based Vaccine and a Trivalent Vaccine in Adults Against COVID-19 in Chile
Phase 2 clinical trial in adults previously vaccinated against SARS-CoV-2 in Chile with an initial schedule of two doses of CoronaVac® plus two booster doses with different vaccines.
- Trial name
- CoronaVarCL (NCT05593042)
- Testing
- CoronaVac®, Omicron Vaccine, Trivalent Vaccine
- Where
- 3 sites in Chile
- Volunteers
- 551 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
SARS-CoV2 Infection, Covid19
Impact of SARS-CoV-2 (COVID-19) Infection, Treated in Ambulatory Care, on Long-term Quality of Life in a Parisian Military Population
In April 2020, a meta-analysis on the long-term sequelae of respiratory syndromes related to seasonal coronaviruses (SARS and MERS) showed a significant alteration in quality of life, with in particular a decrease in physical and…
- Trial name
- COVIDAMBUCMA1 (NCT04893070)
- Testing
- Questionnaires COVID+, Questionnaires COVID-
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
COVID-19 Pneumonia, COVID-19
Clinical, Virological, Serological and Immunological Characteristics During and Following COVID-19 Hospitalization
Assessment of the association between the severity of COVID-19 and SARS-CoV-2 NAb titers levels for up to six months following primary infection using a live virus NAb assay.
- Trial name
- COVISERA (NCT05274373)
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- Nordsjaellands Hospital
Corona Virus Infection, COVID
Assessing the Safety of Pregnancy In the CoRonavirus (COVID-19) pandEmic
Prospective nationwide cohort study of pregnant women enrolled early in gestation and followed for Covid-19 exposure and infection, with follow up of obstetrical outcomes and infant development through the first year of life.
- Conditions
- Corona Virus Infection, COVID, Pregnancy Related, Early Pregnancy
- Trial name
- ASPIRE (NCT04388605)
- Where
- United States
- Volunteers
- 7,965 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
COVID-19
Safety and Immunogenicity Study of EgyVax Vaccine Candidate for Prophylaxis of COVID-19 Infection
This is a phase I, prospective, three-arm, open-label, randomized, first in human (FIH) clinical trial to assess the safety and immunogenicity of EgyVax vaccine candidate for prophylaxis of SARS-CoV-2 infection (COVID-19).
- Trial name
- Sphinx (NCT05218070)
- Testing
- EgyVax Vaccine Candidate
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Eva Pharma
Covid19
SuPAR in Adult Patients With Covid-19
The biomarker soluble urokinase plasminogen activator receptor (suPAR) is the soluble form of the cell membrane-bound protein urokinase plasminogen activator receptor (uPAR), which is expressed mainly on immune cells, endothelial…
- Trial name
- SPARCOL (NCT04590794)
- Testing
- Soluble Urokinase Plasminogen Activator Receptor
- Where
- Greece
- Volunteers
- 767 people
- Sponsor
- University of Thessaly
Use of Stem Cells for COVID-19 Treatment
Treatment of COVID-19 Patients Using Wharton's Jelly-Mesenchymal Stem Cells
The purpose of this study is to investigate the potential use of Wharton's Jelly Mesenchymal stem cells (WJ-MSCs) for treatment of patient diagnosed with Corona Virus SARS-CoV-2 infection, and showing symptoms of COVID-19.
- Trial name
- NCT04313322
- Testing
- WJ-MSCs
- Where
- Jordan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Stem Cells Arabia
Long COVID
Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19
Plain Language Summary: This study is a clinical trial to see if ketamine can help treat symptoms of Long COVID, especially fatigue and problems with thinking clearly (often called "brain fog").
- Trial name
- NCT06821087
- Testing
- Ketamine only
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
COVID-19
Investigation of Subsequent and Co-infections Associated With SARS-CoV-2 (COVID-19)
Multicenter retrospective chart review of patients admitted to any of the four Methodist Health System hospitals
- Trial name
- NCT04561193
- Testing
- Observational
- Where
- United States
- Volunteers
- 417 people
- Sponsor
- Methodist Health System
COVID-19
AZD1222 Vaccine for the Prevention of COVID-19
The purpose of this study is to evaluate safety and immunogenicity of AZD1222 for COVID-19 prevention in the Russian Federation
- Trial name
- NCT04540393
- Testing
- AZD1222
- Where
- 4 sites in Russia
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
COVID-19
Non-contact ECG Sensor System for COVID19
The purpose of this study is two-fold. First we would like to confirm that non-contact ECG provides equivalency to current contact methods of obtaining ECG data.
- Trial name
- NCT04341506
- Testing
- Non-contact ECG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern Medicine
COVID-19, Placenta Diseases
Angiogenic Factors in the Placentas of Women With COVID-19
Aim: There have been few studies since the beginning of the pandemic researching the histopathologies and conducting molecular investigations of the placentas of SARS-CoV-2 positive pregnant women.
- Conditions
- COVID-19, Placenta Diseases, Angiogenesis
- Trial name
- NCT06644521
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
SARS-CoV-2
Lactoferrin for Prevention of COVID-19 in Health Care Workers
Clinical trial in health care personnel (physicians, nurses or nurse assistants) to determine the effect of orally-administered bovine lactoferrin to prevent SARS-CoV-2 infection.
- Trial name
- LF-COVID (NCT04526821)
- Testing
- Bovine Lactoferrin, Maltodextrin
- Where
- 2 sites in Peru
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
SARS-CoV-2
Moderna COVID-19 Vaccine mRNA-1273 Observational Pregnancy Outcome Study
The main goal of this study is to evaluate the outcomes of pregnancy in females exposed to the Moderna COVID-19 vaccine (mRNA-1273) during pregnancy.
- Trial name
- NCT04958304
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
COVID19
Risks of COVID19 in the Pregnant Population
It is unclear how COVID19 can be passed from mother to infant. The study investigators aim to collect maternal and neonatal samples from COVID19-infected pregnant women and compare them to pregnant women who have clinical…
- Trial name
- NCT04379284
- Testing
- Biospecimen collection
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Mayo Clinic
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