Clinical trials: Viral Respiratory Infection
Covid19, Angiogenesis
Endothelial Damage and Angiogenesis Biomarkers During COVID-19
Severe SARS-CoV-2 disease is characterized by a progressive hypoxemic respiratory failure. Autopsies from these patients show severe endothelial damage with extensive vascular thrombosis, microangiopathy, and occlusion of…
- Conditions
- Covid19, Angiogenesis, Endothelial Dysfunction, Cardiovascular Morbidity
- Trial name
- NCT04609332
- Testing
- Endothelial damage and angiogenic biomarkers
- Where
- Chile
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chile
Covid19, Mucormycosis
Mucormycosis in COVID-19
The purpose is to allow phsyician reporters to contribute to MUNCO registry. Mucormycosis in COVID-19 is a rapidly escalating medical emergency reported in high numbers in India during the ongoing coronavirus surge.
- Conditions
- Covid19, Mucormycosis, Aspergillosis, Candida Infection
- Trial name
- MUNCO (NCT04935463)
- Where
- United States
- Volunteers
- 728 people
- Sponsor
- Montefiore Medical Center
COVID-19, Olfactory Disorder
Fluvoxamine to Augment Olfactory Recovery For Long COVID-19 Parosmia
This study will investigate the efficacy of oral fluvoxamine in olfactory improvement following Covid-19- associated parosmia. This is a randomized, double-blinded, placebo-controlled trial.
- Conditions
- COVID-19, Olfactory Disorder, Parosmia
- Trial name
- FluCOP (NCT05216614)
- Testing
- Fluvoxamine
- Where
- United States
- Sponsor
- Washington University School of Medicine
COVID-19
The Use of Chinese Herbal Medicine and Vitamin C by Hospital Care Workers in HK to Prevent COVID-19
This is a prospective randomized controlled trial study to explore whether the combination of Chinese herbal medicine and Vitamin C is effective and safe to prevent COVID-19 transmission among health care workers in Hong Kong…
- Trial name
- CHM-Cov-19-RCT (NCT05360004)
- Testing
- Chinese herbal medicine
- Volunteers
- 652 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
COVID-19
Worldwide Trends on COVID-19 Research After the Declaration of COVID-19 Pandemic
On 11th of March 2020, WHO characterized COVID-19 infection as a Pandemic. After the COVID-19 infection is declared as a Pandemic there was an outburst regarding COVID-19 Research.
- Trial name
- NCT04460547
- Testing
- Convalescent Plasma Transfusion, Hydroxychloroquine, DAS181
- Volunteers
- 200 people
- Sponsor
- Qassim University
Post COVID-19 Condition, Post-COVID-19 Syndrome
The COPE Study: Pilot Intervention to Improve Symptom Self-management and Coping in Adults With Post COVID-19
This project is a randomized controlled pilot trial using mixed methods to examine the feasibility, acceptability, and initial effects of a telemedicine group-based intervention designed to improve symptom management and coping…
- Trial name
- NCT05658536
- Testing
- 6-Week Self-Management Group
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Washington
Coronavirus Infection, COVID
Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation
In December 2019 in the city of Wuhan in China, a series of patients with unclear pneumonia was noticed, some of whom have died of it.
- Conditions
- Coronavirus Infection, COVID, SARS-CoV 2, Respiratory Failure
- Trial name
- CYCOV-II (NCT04385771)
- Testing
- vv-ECMO + cytokine adsorption (Cytosorb adsorber), vv-ECMO only (no cytokine adsorption)
- Where
- 3 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Dr. Alexander Supady
COVID-19
QT-Logs : Artificial Intelligence for QT Interval Analysis of ECG From Smartwatches in Patient Receiving Treatment for Covid-19
This observational pilot prospective study will evaluate a new method for remote monitoring of corrected QT measurement using an artificial intelligence (AI)-based solution and ECG data collected via smartwatches (AI-QTc), in…
- Trial name
- QT-Logs (NCT04371744)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Covid19
Vital Sensor Monitors for CV19 Detection
This study will monitor physical bio-markers such as heart rate, respiratory rate, and temperature to detect potential COVID-19 infections.
- Trial name
- NCT04635787
- Testing
- ANNE One
- Where
- United States
- Volunteers
- 324 people
- Sponsor
- Northwestern University
Patient Hospitalized in Disease Infectious Unit, Patient Hospitalized in Intensive Reanimation Unit
Study of the Consequences of Infection on Compliance of Modalities of Decisions of Limitations and Stops of Treatments (COVID-19-LAT)
This survey is performed to examine if during the Covid's crisis, the practitionner's have respected the modalities of the law about the end of life, in particular concerning limitations and stop of therapeutics
- Conditions
- Patient Hospitalized in Disease Infectious Unit, Patient Hospitalized in Intensive Reanimation Unit, Patient Hopsitalized in Internal Medicine Unit
- Trial name
- COVID-19-LAT (NCT04452487)
- Testing
- decisions of limitations and stop processing
- Where
- 3 sites in France
- Volunteers
- 2,500 people
- Sponsor
- University Hospital, Clermont-Ferrand
Post-acute Corona Virus 19 (COVID-19) (Long COVID)
Phase 2 Study of RSLV-132 in Subjects With Long COVID
The purpose of this study is to assess the efficacy (decrease in profound fatigue), safety and pharmacokinetics of RSLV-132 in subjects with long Corona Virus (COVID) syndome
- Trial name
- NCT04944121
- Testing
- RSLV-132, Sodium Chloride 0.9%
- Where
- 5 sites in United States
- Volunteers
- 112 people
- Sponsor
- Resolve Therapeutics
Pneumonitis, SARS-CoV Infection
GLS-1027 for the Prevention of Severe Pneumonitis Caused by SARS-CoV-2 Infection (COVID-19)
This clinical trial will evaluate the safety, tolerability and efficacy of GLS-1027 in the prevention of severe pneumonitis caused by SARS-CoV-2 infection
- Trial name
- NCT04590547
- Testing
- GLS-1027
- Where
- 17 sites in United States, Bulgaria and 3 more
- Volunteers
- 132 people
- Sponsor
- GeneOne Life Science, Inc.
COVID-19
NutriCovid30 : Nutritional Evaluation for Covid-19 Infection at D30
Describe the main clinical features impacting the food intake, and therefore the nutritional status of a population infected by a coronavirus.
- Trial name
- NCT04365816
- Testing
- Interview
- Where
- France
- Volunteers
- 403 people
- Sponsor
- University Hospital, Grenoble
COVID 19
Therapeutic Plasma Exchange in Resistant Cytokine Storm of COVID 19
This research is planned to illustrate the efficacy of Therapeutic Plasma Exchange (TPE) treatment in COVID-19 patients with resistant cytokine storm state.
- Trial name
- NCT04457349
- Testing
- Therapeutic Plasma Exchange (TPE)
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Alexandria University
Pregnancy Related, COVID
imPROving prenaTal carE During ConfinemenT
This study is a non-randomized, quasi-experimental, monocentric study comparing two prenatal monitoring modes in low-risk pregnancy: including at least one remote consultation (phone or teleconsultation) versus face-to-face…
- Trial name
- PROTECT (NCT04368832)
- Testing
- Remote consultation
- Where
- France
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
COVID-19
MG Granules Improve COVID-19 Efficacy and Safety of Convalescent Exercise Tolerance
The global coronavirus pandemic has infected nearly 659 million people and killed more than 6.6 million in the past three years.
- Trial name
- NCT05722093
- Testing
- Manzi Guben granules
- Volunteers
- 360 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
COVID-19, Coronavirus
Outcomes of Elective Cancer Surgery During the COVID-19 Pandemic Crisis
CovidSurg-Cancer is an international, multicentre, observational cohort study designed to evaluate the 30-day COVID-19 infection rates in elective cancer surgery during the COVID-19 pandemic.
- Conditions
- COVID-19, Coronavirus, Cancer, Surgery
- Trial name
- CovidSurg-Can (NCT04384926)
- Testing
- Elective Cancer Surgery
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- University of Birmingham
Covid 19
IMU-838 and Oseltamivir in the Treatment of COVID-19
To evaluate whether time-to-improvement is significantly better in IMU-838 plus Oseltamivir (IONIC Intervention) and standard care vs. Oseltamivir and standard care in adult subjects with coronavirus disease (COVID-19)
- Trial name
- IONIC (NCT04516915)
- Testing
- IMU-838, Oseltamivir
- Where
- United Kingdom
- Volunteers
- 38 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Coronavirus Disease 2019, Character of the Severe Patients
The Clinical Difference Between the Nonfatal Patients and the Fatal Patients With Severe COVID-19
To investigate the difference of the difference between the nonfatal Coronavirus Disease 2019 (COVID-19) Patients and the fatal Patients .The cross sectional study was undertaken to compare the clinical information (laboratory…
- Trial name
- NCT04403009
- Testing
- no intervention
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
COVID 19
Hydroxychloroquine, Oseltamivir and Azithromycin for the Treatment of COVID-19 Infection: An RCT
To evaluate the effectiveness of Hydroxychloroquine Sulfate (200 mg orally 8hr thrice a day for 5 days) vs oseltamivir (75 mg orally twice a day for 5 days) vs Azithromycin (500 mg orally daily on day 1, followed by 250 mg orally…
- Trial name
- PROTECT (NCT04338698)
- Testing
- Hydroxychloroquine, Oseltamivir, Azithromycin
- Where
- 11 sites in Pakistan
- Volunteers
- 550 people
- Sponsor
- Shehnoor Azhar