Clinical trials: Viral Respiratory Infection
Aging, Falling
Effectiveness of Online Exercise Training in Geriatric Population During COVID-19
The aim of this study is to investigate the effectiveness of online exercise training in geriatric population whose daily life activity level decreased during COVID-19 pandemic.
- Conditions
- Aging, Falling, Dependence, Inactivity, Physical
- Trial name
- NCT06548880
- Testing
- Structured exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medipol University
Bronchiolitis
High Flow Nasal Cannula Use in Infants With Bronchiolitis
Infants with viral bronchiolitis are currently treated with oxygen therapy if oxygen saturation is low. In earlier observational clinical studies, the use of high flow nasal cannulae therapy in infants with bronchiolitis has been…
- Trial name
- NCT02737280
- Testing
- Airvo (TM, Fisher & Paykel Healthcare) - High flow oxygen therapy, MedKit Finland - Usual oxygen therapy
- Where
- 4 sites in Finland
- Volunteers
- 18 people
- Sponsor
- University of Oulu
Acute Viral Respiratory Infection
Botanical Therapy for Acute Viral Respiratory Infections
This Phase 1 study will evaluate the feasibility and safety of implementing a host pathologic state-directed botanical therapeutic platform in adults with acute viral respiratory infections.
- Trial name
- DPBT-AVRI (NCT07805447)
- Testing
- PurInf I Botanical Formulation, PurInf II Botanical Formulation, PurInf III Botanical Formulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- All Natural Medicine Clinic, LLC
Vascular Stiffness, Cardiorespiratory Fitness
Comparison of Home- vs. Gym-based Exercise Delivery Modes
Home-based exercise interventions were the only alternatives to attenuate physical deconditioning and ameliorate traditional and emergent cardiovascular risk factors progression during the COVID-19 outbreak.
- Trial name
- UPSIDE DOWNS (NCT05701943)
- Testing
- Home-Based, Gym-Based
- Where
- Portugal
- Volunteers
- 17 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Covid19, Hypertension
Inspiratory Muscle Trainer and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) COVID-19 Persistent Symptoms
Inspiratory muscle training considered as safe and valid method to improve respiratory muscle strength and functional capacity among uncountable conditions which could improve post COVID-19 persistent symptoms including but not…
- Conditions
- Covid19, Hypertension, Corona Persistent Symptoms
- Trial name
- NCT04919031
- Testing
- Inspiratory muscle trainer, diaphragmatic release
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Covid19, Physical Disability
Activity Level and Quality of Life of Individuals With Physical Disabilities
This study; It will be done in order to compare the quality of life and physical activity levels of physically disabled individuals who continue and do not continue rehabilitation during COVID-19.
- Conditions
- Covid19, Physical Disability, Quality of Life
- Trial name
- NCT04900402
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
COVID-19
Pan-European Study on Geriatric Rehabilitation After COVID-19 Disease
Older and more vulnerable persons are more likely to get very ill when infected with the coronavirus, and have the highest COVID-19 morbidity and mortality rate.
- Trial name
- EU-COGER (NCT05749731)
- Where
- 51 sites in Czechia, Germany and 8 more
- Volunteers
- 723 people
- Sponsor
- Leiden University Medical Center
Coronavirus
Convalescent Plasma to Limit Coronavirus Associated Complications
Researchers are trying to assess the treatment potential and safety of anti-SARS-CoV-2 convalescent plasma in patients with acute respiratory symptoms with confirmed COVID-19.
- Trial name
- NCT04325672
- Testing
- Convalescent Plasma
- Sponsor
- Mayo Clinic
Covid19
Application of Machine Learning Based Approaches in Emergency Department to Support Clinical Decision Managing SARS-CoV-2 Infected Patients
The aim of the study is to develop a prognostic prediction model based on machine learning algorithms in patients affected by coronavirus disease 2019 (COVID-19), the prediction model will be capable to recognize patient with…
- Trial name
- NCT04825301
- Where
- Italy
- Volunteers
- 779 people
- Sponsor
- University of L'Aquila
Contamination by COVID 19 During Oral Care
Risk of Contamination by COVID-19 During Oral Care With Aerosolization
The sudden Covid-19 pandemic has led all healthcare workers to adapt to an unprecedented situation by continuing to provide care while protecting themselves and their patients.
- Trial name
- Bu-Covid (NCT04817319)
- Testing
- Oral care with/without aerosolization
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19, Virus Diseases
Personalised Immunotherapy for SARS-CoV-2 (COVID-19) Associated With Organ Dysfunction
Our aim is to conduct one trial of personalized immunotherapy in patients with SARS-CoV-2 (COVID-19) associated with organ dysfunction and with laboratory findings of macrophage activation syndrome or immune dysregulation.
- Conditions
- COVID-19, Virus Diseases, Macrophage Activation Syndrome, Corona Virus Infection
- Trial name
- ESCAPE (NCT04339712)
- Testing
- Anakinra, Tocilizumab
- Where
- 17 sites in Greece
- Volunteers
- 102 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Ventilation During Resuscitation
Mouth-to-mouth Ventilation Efficiency Through Breathable Self-sterilizing Respirator During BLS in COVID-19 Pandemic
Complex practical BLS training have been stopped all over the world due to COVID-19 pandemic in 2020. While launching the new Simulation Centre at Medical Faculty of Masaryk University in Brno, Czech Republic, teachers and…
- Trial name
- MOVERESP (NCT04867265)
- Testing
- Mout-to-mouth ventilation, Mout-to-mouth ventilation with quantitative analysis
- Where
- Czechia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
SARS-CoV-2 Infection, COVID-19
Study to Describe the Safety, Tolerability, Immunogenicity, and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals
This is a Phase 1/2/3, randomized, placebo-controlled, observer-blind, dose-finding, vaccine candidate-selection, and efficacy study in healthy individuals.
- Trial name
- NCT04368728
- Testing
- BNT162b1, BNT162b2, BNT162b2SA
- Where
- 175 sites in United States, Argentina and 4 more
- Volunteers
- 46,969 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Dental Anxiety, Covid19
Music for Decreasing Dental Anxiety During Oral Surgery in Coronavirus Disease 2019 (COVID-19)
Approximately 100 patients undergoing oral surgery will be divided in 3 groups of musical audition to control anxiety: baroque (N=35), classicism (N=35) and control group (N=30).
- Trial name
- NCT05052034
- Testing
- Music
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- European University of Madrid
Cross Sectional Hospital Based Study
Risk Perception Associated With Covid-19 Among Anesthetists
Since the outbreak of the COVID-19 pandemic, the anesthesiologists are involved in the riskiest interventions e.g. airway management, endotracheal intubation, and resuscitation.
- Trial name
- NCT04861272
- Testing
- Survey
- Where
- Saudi Arabia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- King Saud University
Influenza, COVID-19
Influenza & COVID-19 Obstetric and Perinatal Epidemiology Study in India
This study will be conducted as a prospective cohort study, enrolling all eligible women in their first trimester of pregnancy during a baseline visit during week 6-13 of pregnancy at Government Medical College Hospital, Nagpur.
- Conditions
- Influenza, COVID-19, SARS-COV-2 Infection, Other Respiratory Viruses
- Trial name
- ICOPE (NCT06168019)
- Testing
- Exposures
- Where
- 2 sites in United States, India
- Volunteers
- 10,000 people
- Sponsor
- Boston University
Sepsis, Viral Pneumonia
Discover the Immune Signature of Sepsis Caused by Acute Pulmonary Infection: A Cohort Study
The goal of this observational study is to describe the immune signature of acute pulmonary infection.The main questions it aims to answer are: 1. Nasal mucosal immune response in patients with influenza infection 2.
- Conditions
- Sepsis, Viral Pneumonia, Influenza, Upper Respiratory Tract Infection
- Trial name
- DISPLAY (NCT05612893)
- Testing
- pathogen
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Covid19
Persistence of Neutralizing Antibodies 6 and 12 Months After a Covid-19
Covid-19 is associated with the onset of anti-SARS-CoV-2 antibodies; in a majority of patients, neutralizing antibodies are detected. However, the long-term persistence of such protective antibodies is not known.
- Trial name
- PANCOLIN (NCT04543006)
- Testing
- serology
- Volunteers
- 170 people
- Sponsor
- University Hospital, Grenoble
Cardiomyopathies
Myocardial Involvement of Severe Acute Respiratory Syndrome-Cov-2 (Covid19) Infected Patients
The effects of severe acute respiratory syndrome SARS-Cov-2 (Covid-19) on the myocardium and their role in the clinical course of infected patients are still unknown.
- Trial name
- COCARDE (NCT04358952)
- Testing
- Global Longitudinal Strain
- Where
- France
- Volunteers
- 122 people
- Sponsor
- University Hospital, Toulouse
Cancer
Immune Responses in Oncology Patients to Novel Coronavirus Vaccines (IROC)
The goals of this study are to assess initial or booster vaccine performance (safety and efficacy) and to collect serum and peripheral blood mononuclear cells (PBMCs) pre and post-vaccination to assess immune and other response…
- Trial name
- NCT04930055
- Testing
- COVID-19 Vaccination
- Where
- 2 sites in United States
- Volunteers
- 2,206 people, healthy volunteers welcome
- Sponsor
- Indiana University