Clinical trials: Viral Respiratory Tract Infections
Coronavirus Infection, COVID-19
WGS Analysis of COVID-19 Positive Patients
We aim to better understand the mode of action of COVID-19 in the context of its interaction with the host genome through whole-genome sequencing.
- Trial name
- NCT04353401
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Vanda Pharmaceuticals
Covid19
OCTA Study: Retinal Vascular Changes in Patients With SARS-CoV-2 Infection
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that have been affected by COVID-19.
- Trial name
- NCT04601012
- Testing
- Optical coherence tomography angiography
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
COVID-19
Prevalence of DVT or PE in Patients Infected With COVID-19 Admitted to Hospital
The main objectives are: To establish the prevalence of deep venous thrombosis through ultrasonography in Patients infected with COVID-19 admitted to hospital. To identify patients with higher risk of deep venous thrombosis.
- Trial name
- SCREENING (NCT04380792)
- Where
- Spain
- Volunteers
- 2,497 people
- Sponsor
- Manuel Monreal
COVID-19, Cytokine Storm
CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19
COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2. COVID-19 causes life threatening complications known as Cytokine Release Syndrome or Cytokine Storm and Acute Respiratory Distress…
- Conditions
- COVID-19, Cytokine Storm, Acute Respiratory Distress Syndrome
- Trial name
- CORONA (NCT04378244)
- Testing
- DeltaRex-G
- Sponsor
- Aveni Foundation
COVID-19
Clinical Trial of Mycobacterium w in COVID-19 Positive Patients, Hospitalized But Not Critically Ill
This is a randomized, double blind, two arms, placebo controlled, clinical trial to study to evaluate the the safety and efficacy of Mycobacterium w in combination with standard of care versus placebo with standard of care for…
- Trial name
- NCT04358809
- Testing
- Suspension of heat killed (autoclaved) Mycobacterium w
- Where
- 4 sites in India
- Volunteers
- 480 people
- Sponsor
- Cadila Pharnmaceuticals
COVID-19, Acute Kidney Injury
Applying Artificial Intelligence to Identify Subphenotypes of Acute Kidney Injury in Mexican Patients With Severe COVID-19
The goal of this observational study was to identify subphenotypes of acute kidney injury patients with COVID-19, and the investigators analyzed their impact on mortality.
- Trial name
- IA-COVAKI (NCT06471101)
- Testing
- clusters
- Where
- Mexico
- Volunteers
- 2,934 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
COVID-19
A Phase 3 Randomized, Double-Blind Placebo Controlled, Multi-regional Trial to Evaluate the Efficacy and Safety of GT0918 for the Treatment of Mild to Moderate COVID-19 Male Patients
The purpose of this study is to assess the efficacy and safety of Proxalutamide (GT0918) in male outpatients with mild to moderate COVID-19 disease
- Trial name
- NCT04869228
- Where
- Brazil
- Volunteers
- 380 people
- Sponsor
- Suzhou Kintor Pharmaceutical Inc,
COVID 19
Transpulmonary Pressure Measurements in Intubated Children With Covid-19 Respiratory Failure
The purpose of this study is to gather information to help doctors understand how Covid-19 affects the lungs in children.
- Trial name
- NCT04519411
- Testing
- Transpulmonary pressure measurements
- Sponsor
- Mayo Clinic
Covid19, Obstetric Anesthesia
Obstetric Anesthesia Experiences in COVID-19 Positive Patients
At the end of 2019, a new coronavirus named COVID-19 (SARS-CoV-2), one of the lower respiratory tract samples was detected in China.
- Trial name
- NCT04691934
- Testing
- Anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Turkiye Yuksek Ihtisas Education and Research Hospital
COVID-19, Vaccine
Evaluation of Menstrual Irregularities and Abnormal Uterine Bleeding After Covid-19 Vaccine
Covid-19 vaccines offered a good opportunity to counteract the spread of Sars-Cov-2 infection among the general population, reducing significantly both morbidity and mortality.
- Conditions
- COVID-19, Vaccine, Menstrual Irregularity, Menopausal Bleeding
- Trial name
- MECOVAC-1 (NCT05083065)
- Testing
- Covid-19 vaccine
- Where
- Italy
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Alopecia Areata, Alopecia Totalis
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Alopecia Areata (& Ophiasis)
- Trial name
- NCT05098600
- Testing
- Exposure of interest
- Where
- Czechia
- Volunteers
- 123 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
COVID-19
ALBERTA HOPE COVID-19 for the Prevention of Severe COVID19 Disease
Albertans with COVID-19 are at risk of deteriorating and developing severe illness. Those over age 40 or with co-morbid illness, and likely those who are immune suppressed, are at highest risk.
- Trial name
- NCT04329611
- Testing
- Hydroxychloroquine
- Where
- 2 sites in Canada
- Volunteers
- 148 people
- Sponsor
- Dr. Michael Hill
Severe COVID-19
Assessment of Efficacy and Safety of Therapy With COVID-19 Convalescent Plasma in Subjects With Severe COVID-19 (IPCO)
This phase 2b clinical study will enroll adult subjects of both sexes with ARDS due to COVID-19 necessitating invasive mechanical ventilation.
- Trial name
- IPCO (NCT04712344)
- Testing
- COVID-19 convalescent plasma
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
COVID-19
[14C] Study on Mass Balance and Biotransformation of STI-1558 in Healthy Chinese Adult Male Subjects
This trial adopts a single-center, single-dose, single-period, non-randomized, open-label study design. It is planned to enroll 6~8 healthy male subjects, and each subject receives single oral administration of drug solution…
- Trial name
- NCT05754411
- Testing
- [14C]STI-1558
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Zhejiang ACEA Pharmaceutical Co. Ltd.
COVID-19
Clinical Trial For SARS-CoV-2 Vaccine (COVID-19)
This study is a randomized, double-blinded, and placebo controlled phase III clinical trial of the SARS-CoV-2 inactivated vaccine manufactured by Sinovac Research \& Development Co., Ltd.
- Trial name
- NCT04582344
- Testing
- CoronaVac
- Where
- 25 sites in Turkey (Türkiye)
- Volunteers
- 10,214 people, healthy volunteers welcome
- Sponsor
- Health Institutes of Turkey
COVID-19
Effect of Daily Oral Administration of Food Supplement NLC-V in Patients Diagnosed With COVID-19
This study is designed to evaluate the safety and efficacy of NLC-V in patients diagnosed with COVID-19.
- Trial name
- NCT05226767
- Testing
- NLC-V
- Where
- Israel
- Volunteers
- 31 people
- Sponsor
- Todos Medical, Ltd.
COVID-19
Efficacy of the Infusion of Donor Plasma in COVID-19 Infection
Objectives Primary objectives To assess the superiority or not of the infusion of anti-COVID immune plasma infusion versus a placebo (non-immune plasma) to patients over 65 years of age recently infected with the SARS-CoV-2…
- Trial name
- NCT05247307
- Testing
- convalescent plasma infusion covid 19
- Where
- Spain
- Volunteers
- 93 people
- Sponsor
- Hospital Galdakao-Usansolo
Xerostomia, COVID-19
The Use of Photobiomodulation in the Treatment of Oral Complaints of Long COVID-19.A Randomized Controlled Trial.
Coronavirus (COVID-19) is a newly emerging zoonotic agent that emerged in December 2019 in China (2019-nCoV) as a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV -2).
- Conditions
- Xerostomia, COVID-19, Long COVID, Persistent COVID-19
- Trial name
- NCT05760092
- Testing
- Institutional standard treatment for xerostomia and Long Covid, Photobiomodulation Therapy
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Nove de Julho
COVID
Clinical Trial of Allogeneic Mesenchymal Cells From Umbilical Cord Tissue in Patients With COVID-19
The disease caused by the SARS-CoV-2 virus is a viral disease that infects the lungs, producing flu-like symptoms. Elderly infected patients and/or those with co-morbidities may suffer from acute respiratory distress syndrome due…
- Trial name
- MESCEL-COVID19 (NCT04366271)
- Testing
- Mesenchymal cells, Standard of care
- Where
- 6 sites in Spain
- Sponsor
- Hospital Infantil Universitario Niño Jesús, Madrid, Spain
Covid19, Hydrogen-oxygen Gas
Hydrogen-Oxygen Generator With Nebulizer for Adjuvant Treatment of COVID-19 Positive Patients
This is a prospective, multicenter, randomized, controlled, superiority clinical trial. It is expected that the test group would have better effectiveness than the control group in the primary evaluation indicator (time to…
- Conditions
- Covid19, Hydrogen-oxygen Gas, AMS-H-03
- Trial name
- NCT05539664
- Testing
- Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03, the hospital routine oxygen supply equipment (wall oxygen or cylinder oxygen)
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Ruijin Hospital
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