Clinical trials: Visceral Hypersensitivity
Insulin Sensitivity and Lipid Metabolism
How Menopause Affects Lipid Metabolism in the Visceral Fat Depots
The purpose of the study is to describe the molecular mechanisms related to an increased visceral fat mass and changed T-cell homeostasis.
- Trial name
- NCT02524457
- Testing
- This is an observational study. There are no interventions
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostatic Neoplasms, Neoplasm Metastasis
A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)
The purpose of this study is to learn whether adding abemaciclib to abiraterone plus prednisone prolongs the time before prostate cancer gets worse. Participation may last approximately 60 months.
- Conditions
- Prostatic Neoplasms, Neoplasm Metastasis, Urogenital Neoplasms, Physiological Effects of Drugs
- Trial name
- CYCLONE 3 (NCT05288166)
- Testing
- Abemaciclib, Abiraterone, Prednisone or Prednisolone
- Where
- 266 sites in United States, Argentina and 22 more
- Volunteers
- 925 people
- Sponsor
- Eli Lilly and Company
Irritable Bowel Syndrome
Citalopram in Irritable Bowel Syndrome
Hypotheses: 1. Primary null hypothesis: The rate of clinical response, assessed as patient-reported global symptom rating and "adequate relief of IBS symptoms," does not differ between non-depressed IBS patients treated with the…
- Trial name
- NCT00477165
- Testing
- Citalopram
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Stanford University
Dysmenorrhea, Pain
Examining the Role of Improved NSAID Management in Treating Dysmenorrhea and Bladder Pain
The goal of this study is to see if optimized use of naproxen for treatment of dysmenorrhea will improve pain report from baseline.
- Trial name
- NCT03697720
- Testing
- Naproxen
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Endeavor Health
Heartburn, Dyspepsia
The Effects of Tegaserod on Mechanical Sensitivity of the Esophagus and Stomach in Patients With Heartburn and Dyspepsia.
Investigate the role of tegaserod in modulating gastric sensitivity to mechanical distention of the stomach
- Trial name
- NCT00171457
- Testing
- Tegaserod
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Novartis
Prostate Cancer, Organoid
Observation of Clinical Consistency of Organoid-chips Drug Sensitivity in Chemotherapy for PCa With Visceral Metastasis
This project plans to establish an organoid chip model of prostate cancer patients with internal organ metastasis from surgical or biopsy tissue sources, and test the sensitivity of commonly used chemotherapy drugs based on…
- Trial name
- NCT06536725
- Testing
- Building Organoid-on-chips models
- Where
- 2 sites in China
- Volunteers
- 35 people
- Sponsor
- Tianjin Medical University Second Hospital
Irritable Bowel Syndrome (IBS)
New Microbiota-endocrine Axis in Fructose Malabsorption-caused Visceral Hypersensitivity in Irritable Bowel Syndrome.
Irritable bowel syndrome (IBS) affects around 4% of the general population and remains the most common functional bowel disorder.
- Trial name
- ENDOLORII (NCT07337707)
- Testing
- urine intestinal permeability test or lactulose/mannitol test, Blood test, food diary
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Rouen