Clinical trials: Vision, Ocular
Obstructive Sleep Apnea Syndrome, Glaucoma
Obstructive Sleep Apnea Syndrome in Glaucoma
The aim of the study is to determine if plasma matrix-metalloproteinase activity can predict glaucoma in patients with OSAS and if the level of plasma matrix-metalloproteinase activity will decrease after one month of…
- Trial name
- NCT00313092
- Testing
- nCPAP treatment
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Selim Orguel
Open Angle Glaucoma, Ocular Hypertension
Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension
The objective of this clinical study is to evaluate the safety and efficacy of NCX 470 Ophthalmic Solution in lowering intraocular pressure (IOP) in patients with ocular hypertension or open-angle glaucoma.
- Trial name
- Mont Blanc (NCT04445519)
- Testing
- NCX 470 0.065% (initial phase of trial), Latanoprost 0.005% (initial phase of trial), NCX 470 0.1% (initial phase of trial)
- Where
- United States
- Volunteers
- 691 people
- Sponsor
- Nicox Ophthalmics, Inc.
Hyperopia, Presbyopia
The VIS Opti-K Low Vision Aid Device Provides Vision Improvement.
The VIS Opti-K Low Vision Aid device will be used to provide vision improvement to patients with refractive disorders (hyperopia and presbyopia).
- Trial name
- Opti-K Pres (NCT06597292)
- Testing
- Vision improvement
- Where
- 2 sites in United States, Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VIS, Inc.
Age-related Macular Degeneration, Diabetic Vascular Diseases
Comfort and Antimicrobial Efficacy of Chlorhexidine vs Betadine for Intravitreal Injections
The purpose of this prospective interventional study is to compare patient experience, ocular surface irritation, and bacterial colony counts and microbial spectrum between povidine iodine and aqueous chlorhexidine as ocular…
- Conditions
- Age-related Macular Degeneration, Diabetic Vascular Diseases, Proliferative Retinopathy, Retina Vein Occlusion
- Trial name
- NCT03571100
- Testing
- Chlorhexidine, Povidine-Iodine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- MidAtlantic Retina
Open-angle Glaucoma, Ocular Hypertension
Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV®
The purpose of this study is to evaluate the additive intraocular pressure (IOP) lowering effect of Brinzolamide 1%/Brimonidine 0.2% (SIMBRINZA®) dosed twice daily (BID) when added to Travoprost 0.004%/Timolol 0.5% (DUOTRAV®) in…
- Trial name
- NCT02730871
- Testing
- Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension, Brinzolamide/brimonidine vehicle, Travoprost 0.004%/timolol 0.5% solution
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Alcon Research
Guillain-Barré Syndrome, Miller Fisher Syndrome
International Guillain-Barré Syndrome Outcome Study
International GBS Outcome Study (IGOS) is a study conducted by the members of the Inflammatory Neuropathy Consortium (INC) and Peripheral Nerve Society (PNS) on disease course and outcome in Guillain-Barré syndrome (GBS).
- Trial name
- IGOS (NCT01582763)
- Where
- 138 sites in United States, Argentina and 19 more
- Volunteers
- 2,000 people
- Sponsor
- Erasmus Medical Center
Glaucoma, Open-Angle
Early Evaluation of the Beacon Aqueous Microshunt in Patients Refractory to Drug Therapy in the European Union
This is prospective, non-randomized, single-arm study to assess the safety and effectiveness of lowering intraocular pressure with the Beacon Aqueous Microshunt. A total of 65 subjects will be enrolled at five centers.
- Trial name
- EARLY BIRD EU (NCT03634319)
- Testing
- Beacon Aqueous Microshunt
- Where
- 2 sites in Germany
- Volunteers
- 10 people
- Sponsor
- MicroOptx
Glaucoma, Macular Disease
CEI Van Outreach Screening Study
The primary goal of the trial is to show that optical coherence tomography (OCT) technology can be used to effectively screen for diseases of the eye including glaucoma, macular diseases and keratoconus.
- Conditions
- Glaucoma, Macular Disease, Keratoconus
- Trial name
- NCT01510392
- Testing
- OCT imaging, the FDA Cleared iVue
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
Cone-Rod Degeneration, Rod-Cone Degeneration
Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease
Background: The retina is a thin layer of tissue at the back of the eye. Retinal disease usually reduces a person s mobility because it affects how he or she moves through familiar and unfamiliar environments.
- Trial name
- NCT04289571
- Testing
- VR Mobility Tool
- Where
- 2 sites in United States, Australia
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract
Cataract Surgery Technique and Ocular Clarity
The goal of this study is to study the restoration of quality of vision, expressed as straylight, in the immediate period after cataract surgery with two different phacoemulsification technologies.
- Trial name
- NCT05489198
- Testing
- cataract surgery with Centurion phacoemulsification system, cataract surgery with Quatera 700 phacoemulsification system
- Volunteers
- 15 people
- Sponsor
- Amphia Hospital
Ocular Surface Disease
Comparison Between Lathe Cut Versus Cast Molding Soft Contact Lens Technique on Ocular Surface Integrity
"Comparison between Lathe Cut versus Cast Molding Soft Contact Lens Technique on Ocular Surface Integrity" investigates the impact of two different manufacturing methods on the health and integrity of the ocular surface.
- Trial name
- NCT06495112
- Testing
- Soft contact lens with lathe cut technique Lathe, Soft contact lens with cast molding technique
- Where
- Pakistan
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Superior University
Computer Vision Syndrome, Asthenopia
Yogic Eye Exercises for Computer Vision Syndrome in Female Design Students
Computer vision syndrome (CVS) is a cluster of eye and musculoskeletal complaints - dryness, redness, blurred vision, foreign body sensation, excessive tearing, and neck, shoulder or back pain - that arises from prolonged work at…
- Conditions
- Computer Vision Syndrome, Asthenopia, Eye Strain, Dry Eye
- Trial name
- NCT07816419
- Testing
- Yogic eye exercise programme
- Where
- Saudi Arabia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- King Saud University
Cataracts, Corneal Edema
Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.
The purpose of this clinical research study is to investigate the efficacy of predosing patients undergoing cataract surgery with the potent corticosteroid difluprednate ophthalmic emulsion 0.05% compared to prednisolone acetate…
- Conditions
- Cataracts, Corneal Edema, Retinal Structural Change, Deposit and Degeneration, Visual Acuity Reduced Transiently
- Trial name
- NCT01244334
- Testing
- Difluprednate ophthalmic emulsion 0.05%, Prednisolone acetate 1%
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- Edward J. Holland
Digital Technology, Healthy
A Vision-Based Characterization of Human Movement Scaling in Large-Amplitude Tasks
This pilot study investigates the feasibility of objectively quantifying movement amplitude and amplitude decay during large-amplitude exercises using RGB camera-based video analysis in healthy volunteers.
- Trial name
- NCT07387887
- Testing
- Large-Amplitude Exercise Observation and Video Recording
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Biruni University
Cancer
Imatinib Mesylate And Cyclophosphamide In Metronomic Administration: Dose Escalation Study Of Imatinib Mesylate
The purpose of this study is to determine the maximum tolerated dose of imatinib mesylate, given in association with a fixed dose of cyclophosphamide (50 mg bid).
- Trial name
- PALANGI3 (NCT01046487)
- Testing
- Imatinib mesylate, Cyclophosphamide (Dosing level 1 ), Imatinib mesylate, Cyclophosphamide (Dosing level 2), Imatinib mesylate, Cyclophosphamide (Dosing level 3)
- Where
- 3 sites in France
- Volunteers
- 26 people
- Sponsor
- Centre Oscar Lambret
Age Related Macular Degeneration, Diabetic Retinopathy
Strategies for Improving Linkage-to-Care After Eye Disease Screening
The goal of this randomized, parallel-group, controlled trial is to compare methods of improving linkage-to-care for participants in the Village Integrated Eye Worker II (VIEW II) trial who are referred to the eye hospital…
- Conditions
- Age Related Macular Degeneration, Diabetic Retinopathy, Glaucoma
- Trial name
- NCT06943599
- Testing
- Text Message Reminder, Health Worker Visit
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of California, San Francisco
Amblyopia
OKKO Space Academy to Check Children's Vision at Home
The purpose of this study is to determine the feasibility of the OKKO Space Academy app as a vision measuring and home-monitoring tool for children aged 3-8 years undergoing amblyopia treatment.
- Trial name
- NCT05313516
- Testing
- OKKO Health app
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Pterygium, Dry Eye
Using Impression Cytology to Observe the Cytological Changes of Ocular Surface Cells in Various Ocular Surface Disorders
Currently, due to the advantage of noninvasive, localized, rapid, painless and easily repeatable of impression specimens, the technique is an ideal method of investigating ocular surface disorders when the diagnosis is not…
- Conditions
- Pterygium, Dry Eye, Tumor
- Trial name
- NCT01387971
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Vestibular Function Tests, Nystagmus Vestibular
Post- Rotatory Nystagmus Test: Normative Data for Spanish Adolescents and Adults
The vestibulo-ocular reflex is the motor response of our eyes in the opposite direction to a translational or rotational movement of our head.
- Trial name
- NCT04788134
- Testing
- Post-rotatory nystagmus test
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Quesada, Rocío Vico