Clinical trials: Vision, open to volunteers
Radiation Retinopathy, Visual Impairment
Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy
This randomized controlled trial will evaluate the effect of intravitreal faricimab or fluocinolone acetonide (FAc) intravitreal implant compared with observation on long-term visual acuity following treatment of choroidal…
- Trial name
- AL (NCT05844982)
- Testing
- Faricimab, fluocinolone acetonide
- Where
- 29 sites in United States
- Volunteers
- 600 people
- Sponsor
- Jaeb Center for Health Research
Computer Vision Syndrome
Comparative Effects of Exercises on Pain, Cervical Proprioception, Neck Disability and Visual Performance in Patients With Computer Vision Syndrome.
This study aims to compare the effectiveness of cervical sensorimotor training and oculomotor training in patients with Computer Vision Syndrome (CVS).
- Trial name
- NCT07892040
- Testing
- Cervical Sensorimotor Training, Occulomotor Training
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- University of Management and Technology Lahore
Leber Congenital Amaurosis 10, Blindness
Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)
The purpose of this double-masked, randomized, placebo-controlled, paired-eye study is to evaluate the efficacy, safety and tolerability of Sepofarsen in subjects with Leber Congenital Amaurosis (LCA) due to the c.2991+1655A>G…
- Conditions
- Leber Congenital Amaurosis 10, Blindness, Leber Congenital Amaurosis, Sensation Disorders
- Trial name
- HYPERION (NCT06891443)
- Testing
- sepofarsen
- Where
- 18 sites in United States, Australia and 8 more
- Volunteers
- 32 people
- Sponsor
- Laboratoires Thea
Low Vision Aids
Assessing the Impact of eSight Go At-Home Usage in Individuals With Visual Impairment
This research aims to test the updated version of Gentex's device, eSight Go, an image enhancing wearable device to assist those with vision impairments limiting activities of daily living.
- Trial name
- eSight (NCT07149259)
- Testing
- At Home Use
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brooks Rehabilitation
Vision, Ocular
Visual Attention and Eye Movements
The purpose of this study is to provide information about how the brain processes sensory inputs using visual stimuli throughout various psychophysical experiments.
- Trial name
- NCT03298737
- Testing
- Covert Spatial Attention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Vision Loss Night, Vision Disorders
OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity
The goal of this clinical trial is to learn if Phentolamine Ophthalmic Solution works to treat adults that have had keratorefractive surgery and have decreased visual acuity under mesopic conditions.
- Trial name
- LYNX-3 (NCT07140783)
- Testing
- 0.75% Phentolamine Ophthalmic Solution
- Where
- 20 sites in United States
- Volunteers
- 580 people
- Sponsor
- Opus Genetics, Inc
Vergence Disorders, Binocular Vision Dysfunction
Effectiveness of Osteopathy as an Adjunct to Optometric Vision Therapy in Vergence Disorders
Vergence disorders are common binocular vision conditions that can cause symptoms such as eyestrain, blurred vision, headaches, and difficulty maintaining clear vision during near tasks.
- Conditions
- Vergence Disorders, Binocular Vision Dysfunction, Convergence Insufficiency
- Trial name
- OSTEOVERG (NCT07452679)
- Testing
- Optometric Vision Therapy, Osteopathic Manual Therapy
- Where
- Andorra
- Volunteers
- 100 people
- Sponsor
- Jordi Zaragoza
Visual Loss
Evaluation of a Scalable Educational Intervention for Adjustment and Coping to Vision Loss
The goal of this interventional study is to learn if an educational intervention improves awareness in people experiencing visual loss.
- Trial name
- NCT07715695
- Testing
- audiovisual educational intervention
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Brigham and Women's Hospital
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) and Leber's hereditary optic…
- Trial name
- NCT06792500
- Testing
- Glycerol Tributyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Washington University
Vision and Hearing Loss, Vision Impairment
SENSE-Brain Health Pro for Older Adults With Sensory Loss
The goal of this study is to learn about the outcomes, usability, and accessibility of the online Brain Health Pro program for older adults with hearing difficulties, vision difficulties, or both.
- Conditions
- Vision and Hearing Loss, Vision Impairment, Hearing Impairment, Vision Difficulty
- Trial name
- SENSE-BHPro (NCT07856888)
- Testing
- Brain Health Pro
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Université de Montréal
Vision Disorder, Stroke
Visual Impairment and Functional Visual Performance Following Acquired Brain Injury: A Cross-Sectional Study
This cross-sectional observational study aims to characterize acquired visual impairment in adults with acquired brain injury and to examine the relationship between objectively identified visual impairment and self-reported…
- Conditions
- Vision Disorder, Stroke, Brain Injuries
- Trial name
- NCT07858708
- Where
- Czechia
- Volunteers
- 108 people
- Sponsor
- Charles University, Czech Republic
Schizophrenia, Schizoaffective Disorder
NEURO-COGS: Neurometabolic Mechanisms of Cognitive Training in Schizophrenia
This study will examine brain metabolic and excitatory/inhibitory mechanisms related to cognitive and visual functioning in adults with schizophrenia and healthy control participants.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Cognitive Impairment, Visual Impairment
- Trial name
- NCT07788755
- Testing
- Perceptual Discrimination Training, Cognitive Control Training
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Apple Vision Pro, Image Guided Procedure
Spatial Computing With the Apple Vision Pro in Image-guided Procedures
To learn if it is possible to use Apple Vision Pro (AVP) technology during image-guided procedures.
- Conditions
- Apple Vision Pro, Image Guided Procedure, Spatial Computing
- Trial name
- NCT07819513
- Testing
- CT guided biopsy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Brain Injuries
Pilot Study of Individualized Neurovisual Rehabilitation Following Acquired Brain Injury
This prospective single-group pilot study will evaluate the feasibility and preliminary outcomes of an individualized neurovisual rehabilitation program for adults with visual impairment following acquired brain injury.
- Trial name
- NCT07849582
- Testing
- Individualized Neurovisual Rehabilitation
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- Charles University, Czech Republic
Amblyopia, Amblyopia Unilateral
Non-invasive Induction of Metaplasticity for Amblyopia
The goal of this clinical trial is to determine the efficacy of flicker therapy as an adjunct therapy to treat amblyopia beyond the critical period in adolescents and adults aged 14-40 years who have amblyopia of ≥3 lines of…
- Conditions
- Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
- Trial name
- NIMA (NCT07846397)
- Testing
- Flicker
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Neurocognitive Deficit
Validation of MoCA-B and MoCA-Blind for Screening Cognitive Decline
The objective of this observational study is to assess the efficacy of two neuropsychological tests (MoCA-B and MoCA-Blind) in detecting cognitive decline in older adults.
- Trial name
- NCT07846839
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Optic Neuritis, Optic Neuropathy
Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is Suspected
Optic neuritis is an important cause of acute or subacute visual loss. In clinical practice, optic neuritis must often be distinguished from other optic neuropathies, retinal diseases, anterior-segment or ocular media disorders…
- Conditions
- Optic Neuritis, Optic Neuropathy, Visual Loss
- Trial name
- GX-ICON (NCT07623252)
- Where
- 9 sites in China
- Volunteers
- 500 people
- Sponsor
- First Affiliated Hospital of Guangxi Medical University
Low Vision, Low Vision Aids
Beacon Sensors and Telerehabilitation to Assess and Improve Use of Devices (BeST-AID) for Low Vision
One goal of this research is to conduct a non-inferiority trial of telerehabilitation versus in-office care to provide follow-up training to individuals with low vision to enhance their quality of life by using magnification…
- Trial name
- BeST-AID (NCT06107881)
- Testing
- Low Vision Rehabilitation
- Where
- 9 sites in United States
- Volunteers
- 350 people
- Sponsor
- University of California, Los Angeles
Metamorphopsia, Aniseikonia
Virtual Reality Aniseikonia and Metamorphopsia Testing
The purpose of this study is to assess whether the use of small, lightweight, portable virtual reality headset devices can provide a more accessible, reliable, contained, and convenient testing environment compared to previous…
- Trial name
- NCT07838181
- Testing
- Aegenta VR
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Visual Fatigue, Dry Eye
A Study of Full-Spectrum Screen Lighting for Reducing Screen-Related Eye Fatigue and Dry Eye
This study will evaluate whether full-spectrum screen bar lighting can reduce eye fatigue and dry eye symptoms after a standardized screen task.
- Conditions
- Visual Fatigue, Dry Eye, Computer Vision Syndrome
- Trial name
- NCT07706231
- Testing
- Full-spectrum screen bar light, Brightness-matched screen task without screen bar lighting
- Where
- China
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University