Clinical trials: Vision Disorder
Glaucoma, Neovascular, Vascular Endothelial Growth Factor Overexpression
Intracameral Versus Intravitreal Bevacizumab Injection in NVG: RCT
To prospect studying the efficacy and safety of treating NVG with the intracameral versus the intravitreal injection of Bevacizumab.
- Trial name
- NCT03648814
- Testing
- Intracameral injection, Intravitreal injection
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Prince of Songkla University
Visual Suppression, Amblyopia
Autostereoscopic Dynamic Near Vision Testing
This is an analysis of tests of near vision. Visual perception testing using a novel program on an interactive three dimensional electronic device: Autostereoscopic dynamic near games for monocular visual acuity, stereopsis and…
- Conditions
- Visual Suppression, Amblyopia, Color Vision Defects
- Trial name
- PDICheck (NCT04606355)
- Testing
- Visual Acuity, stereopsis, Color vision
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Tear Film Deficiency
Effect of Obesity on Tear Film and Ocular Health Among Diabetic Patients
To evaluate the effect of obesity on tear film and ocular health in diabetic patients. Research Design An observational cross-sectional study will be conducted.
- Trial name
- NCT06913452
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Superior University
Metastatic Colorectal Cancer
Ocular Blood Flow in Colorectal Cancer Patients
In colorectal cancer therapy anti-angiogenic strategies have become a cornerstone of treatment regimens in the metastatic setting.
- Trial name
- NCT02423785
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Vienna
Supranuclear Palsy, Progressive
Study of the Distractibility Syndrome in Patients With Progressive Supranuclear Palsy
The syndrome of distractibility is a behavioral disorder induced by a lesion or a dysfunction of the frontal lobe. This sign is frequent in patients with progressive supranuclear palsy (PSP), a neurodegenerative disorder with…
- Trial name
- NCT00139373
- Testing
- donepezil
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion
New Non-invasive Modalities for Assessing Retinal Structure and Function
This study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other…
- Conditions
- Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion, Hemianopia, Leber Hereditary Optic Neuropathy
- Trial name
- NCT03475173
- Testing
- LSFG-NAVI
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Randy Kardon
Ocular Inflammation, Infection Associated Blepharitis
Antibiotic Steroid Combination Compared With Individual Administration in the in the Treatment of Ocular Inflammation and Infection
To evaluate the efficacy and safety of fixed combination of azithromycin 1.5% + 0.5% Loteprednol eye drops for the treatment of ocular inflammation and infection associated bacterial blepharitis and / or keratitis and / or…
- Conditions
- Ocular Inflammation, Infection Associated Blepharitis, Keratitis, Conjunctivitis, Bacterial
- Trial name
- NCT01721694
- Testing
- azithromycin 1.5% + Loteprednol 0,5% (separately)
- Where
- Brazil
- Sponsor
- Adapt Produtos Oftalmológicos Ltda.
Hyperopia
Hyperopia Correction Using the NTK Optimal Keratoplasty (Opti-K) System
The purpose of this U.S. Clinical Trial on treatment of sighted eyes is to investigate the safety and effectiveness of optimal keratoplasty (Opti-K™) treatments for hyperopia correction using the NTK Enterprises (NTK) Opti-K…
- Trial name
- NCT01028937
- Testing
- Optimal Keratoplasty
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NTK Enterprises, Inc.
Glaucoma, Ocular Hypertension
Non-Interventional Study In Patients With Ocular Hypertension And Open Angle Glaucoma Treated With Xalatan And Xalacom
Non-interventional study to obtain real life data from the treatment with Xalatan and Xalacom in Germany and to assess the long-term efficacy and tolerability under routine conditions.
- Trial name
- XCHANGE (NCT01012245)
- Testing
- no intervention
- Volunteers
- 28,812 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pharyngitis, Tonsillitis
PASS Study To Evaluate The Potential Of Zithromax To Cause Ocular Problems In Pediatric Patients
This Post-Authorization Safety Study (PASS) is intended to fulfill a regulatory post-marketing requirement to provide data regarding visual abilities in children taking azithromycin (immediate-release formulation) for acute…
- Trial name
- NCT01919996
- Testing
- Azithromycin
- Where
- 6 sites in United States
- Volunteers
- 8 people
- Sponsor
- Pfizer
Glaucoma
Effects of a PF Ophthalmic Solution Containing HA0.4% and TAU 0.5%
Eligible patients underwent evaluation of ocular surface parameters by Ocular Surface Disease Index (OSDI) and Glaucoma Symptom Scale (GSS) questionnaires, Break Up Time test (BUT), Schirmer I test, corneal and conjunctival…
- Trial name
- NCT03480295
- Testing
- Hyaluronic acid 0.4% and Taurine 0.5%, Hyaluronic acid 0.2%
- Volunteers
- 39 people
- Sponsor
- Fondazione G.B. Bietti, IRCCS
Diplopia, Binocular Vision Suppression
Understanding Visual Confusion Using Stereoscopic Displays
In this research study we want to test how people understand a visual scene when the same image is presented to both the eyes, but portions of these images are altered in terms of contrast, depth or in some cases motion.
- Conditions
- Diplopia, Binocular Vision Suppression, Binocular; Fusion, With Defective Stereopsis, Monocular Diplopia
- Trial name
- NCT04957745
- Testing
- Binocular visual confusion (unilateral opaque), Unilateral monocular visual confusion (unilateral see-through), Bilateral monocular visual confusion (bilateral see-through)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Cataract, Glaucoma
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- NCT07218796
- Testing
- Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- SpyGlass Pharma, Inc.
Amblyopia
Electronic Recording of Compliance With Occlusion Therapy for Amblyopia
The purpose of this study was to determine whether compliance with occlusion therapy for amblyopia could be improved and, secondly, if risk factors for non-compliance could be identified.
- Trial name
- NCT00131729
- Testing
- Educational programme
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Advanced/Metastatic NSCLC, Advanced/Metastatic HER2-negative Breast Cancer
A Study Assessing Risk Factors for Oral Mucositis/Stomatitis and Ocular Surface Events in NSCLC and Breast Cancer
This study will identify risk factors for oral mucositis/stomatitis and ocular surface events (OSE) in patients with advanced/metastatic non-small cell lung cancer (NSCLC) and advanced/metastatic human epidermal growth factor…
- Trial name
- NCT06686602
- Testing
- No drug
- Where
- United States
- Volunteers
- 13,759 people
- Sponsor
- Daiichi Sankyo
Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma
Early Diagnosis, Pathogenesis and Progression of Open Angle Glaucoma
The Erlangen Glaucoma Registry is a clinical registry for cross sectional and longitudinal observation of patients with open angle glaucoma (OAG) or glaucoma suspect, founded in 1991.
- Conditions
- Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma, Ocular Hypertension
- Trial name
- NCT00494923
- Where
- Germany
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Amblyopia
Amblyopia Treatment for Children Aged 8 to 12 Years
This study is being done to assess the effect of at-home amblyopia treatment with Curesight™ for children aged 8 to 12 years. Curesight™ allows you to stream any videos on a computer screen at home but the amblyopic eye will see…
- Trial name
- NCT07281742
- Testing
- Curesight dichoptic videos
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Retina Foundation of the Southwest
Wet Macular Degeneration
Sub-tenon Triamcinolone Acetonide in Age-Related Macular Degeneration as Adjunct to Ranibizumab
In the Western World, Age Related Macular Degeneration (ARMD) is a leading cause of blindness. This disease was once thought to be a natural part of aging, but recent research has introduced effective treatments.
- Trial name
- STAR (NCT01249937)
- Testing
- Ranibizumab, Triamcinolone Acetonide
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Chronic Venous Insufficiency, CVI
Respiratory Functions, Aerobic Capacity and Quality of Life in Chronic Venous Insufficiency
This study aims to retrospectively examine the dataset obtained from a previously conducted study titled 'Inspiratory muscle training in individuals with chronic venous insufficiency: randomized controlled trial'.
- Trial name
- NCT06785805
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Izmir Democracy University
Coronary Vasospasm
Effect of Glucose on Ocular Blood Flow
The primary objective is to assess the effect of glucose on retinal vascular diameter in otherwise healthy vasospastic subjects compared to non-vasospastic controls.
- Trial name
- NCT00350129
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland