Clinical trials: Vision Therapy
Pendular Nystagmus, Oculopalatal Tremor
Treatment of Pendular Nystagmus in OPT
Pendular nystagmus corresponds to an enduring to and fro eye oscillation without resetting quick phases. The most common causes of acquired pendular nystagmus (APN) are multiple sclerosis (MS) and focal brainstem lesions…
- Trial name
- NCT02466191
- Testing
- Memantine, Gabapentin
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Hospices Civils de Lyon
Glaucoma
Safety of Topical Insulin Drops for Open-angle Glaucoma
Glaucoma, a leading cause of irreversible blindness worldwide, is characterized by a permanent loss of retinal ganglion cells (RGCs), a group of central nervous system (CNS) neurons that convey visual information from the retina…
- Trial name
- NCT04118920
- Testing
- Topical insulin (4 units), Topical insulin (20 units), Artificial tears
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lateral Epicondylitis, Tennis Elbow
Comparison of Two Different Splints in the Treatment of Lateral Epicondylitis
Lateral epicondylitis (LE) or tennis elbow; is the most common cause of lateral pain in the elbow, with an incidence of 1-3% in the general population.
- Trial name
- NCT04773249
- Testing
- Lateral Epicondylitis Bandage, Wrist Extension Splint
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people
- Sponsor
- Dokuz Eylul University
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Ocular Pain
Evaluate the TetraLens, a Tetracaine Releasing Therapeutic Bandage Contact Lens in Patients Undergoing PRK Procedure
The goal of this clinical trial is to determine the safety, efficacy, and comfort of the investigational TetraLens bandage contact lens in patients who have undergone photorefractive keratectomy (PRK).
- Trial name
- NCT06085352
- Testing
- TetraLens bandage contact lens, Control Acuvue Oasys Bandage contact Lens
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vance Thompson Vision
Homonymous Hemianopsia
Ongoing Effect of Expansion Prisms Following the Discontinuation of Use on Visual Field Enlargement and Retrograde Ganglion Cell Degeneration in Homonymous Hemianopia Patients
The goal of this observational study is to learn about the long-term effects of Pelli prism in Hemianopia patients who take Prisms for awareness of the area they cannot see.
- Trial name
- NCT06674369
- Testing
- Peli prism for hemianopia
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Okan University
Primary Open Angle Glaucoma
CRISPR/Cas9 Instantaneous Gene Editing Therapy to Intraocular Hypertensive POAG With MYOC Mutation
This study is intented to evaluate the safety, tolerability and preliminary efficacy of CRISPR/Cas9 Instantaneous Gene Editing Therapy (BD113 virus-like particle, also BD113vLVP) in patients with primary open-angle glaucoma…
- Trial name
- NCT06465537
- Testing
- BD113vVLP
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Shanghai BDgene Co., Ltd.
Nystagmus
Cross-over Comparison of Gabapentin and Memantine as Treatment for Acquired Nystagmus
Involuntary oscillations of the eyes (nystagmus) impairs vision so that affected patients, who have neurological disorders such as Multiple Sclerosis (MS) , cannot read or watch TV.
- Trial name
- NCT00928954
- Testing
- gabapentin, memantine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Case Western Reserve University
Age Related Macular Degeneration (AMD)
Safety Study of PF582 Versus Lucentis in Patients With Age Related Macular Degeneration
The aim of this study is to test if PF582 (ranibizumab) is safe and similar to Lucentis (ranibizumab). Participants will have a screening visit to check for eligibility.
- Trial name
- NCT02121353
- Testing
- Lucentis, PF582
- Where
- 2 sites in New Zealand
- Volunteers
- 25 people
- Sponsor
- Pfenex, Inc
Behcet's Disease, Panuveitis
Interferon-alpha2a Versus Cyclosporin A for Severe Ocular Behcet's Disease (INCYTOB)
The purpose of this study is to investigate if interferon-alpha2a is superior to the standard treatment with cyclosporin A for the treatment of severe ocular manifestations of Behcet's disease.
- Conditions
- Behcet's Disease, Panuveitis, Posterior Uveitis, Retinal Vasculitis
- Trial name
- INCYTOB (NCT00167583)
- Testing
- Cyclosporin A, Interferon-alpha2a
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- University Hospital Tuebingen
Amblyopia, Amblyopia Unilateral
Valproate for the Treatment of Residual Amblyopia
The goal of this clinical trial is to determine the efficacy of valproate as an adjunct therapy to treat amblyopia beyond the critical period in children aged 8-17 years who have amblyopia of ≥3 lines of interocular…
- Conditions
- Amblyopia, Amblyopia Unilateral, Amblyopia, Anisometropic, Amblyopia Strabismic
- Trial name
- VARA (NCT07226141)
- Testing
- Valproate, Patch
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Boston Children's Hospital
Graft Versus Host Disease in Eye, Ocular Complications
Ocular Complications From Cancer Therapy - Patient Registry and Biobank
The purpose of this study is to collect data on patients seen at University of Maryland after undergoing cancer therapy. Previous medications, ocular history, medical history, clinical evaluations, surgical procedures and…
- Conditions
- Graft Versus Host Disease in Eye, Ocular Complications, Inflammatory Dry Eye Disease
- Trial name
- NCT06874283
- Testing
- Eye exam
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Glaucoma, Glaucoma Eye
MicroPulse TLT - UK Study
This Prospective Interventional Study will assess the efficacy of MPTLT in the UK.
- Conditions
- Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle, Glaucoma Secondary
- Trial name
- MPTLTUKS (NCT05593354)
- Testing
- Micropulse Transscleral laser therapy
- Volunteers
- 250 people
- Sponsor
- Imperial College Healthcare NHS Trust
Primary Open-Angle Glaucoma (POAG)
MEXIDOL® Sequential Therapy of Patients With Primary Open-angle Glaucoma (POAG)
Hypothesis: The use of neurocytoprotectors helps restore the functional activity of mitochondria, improve the nervous activity of the retina and optic nerve, and stabilize the glaucomatous process.
- Trial name
- NCT06437639
- Testing
- Mexidol
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Pharmasoft
Glaucoma, Open-angle
Non Interventional Study With Primary Open Angle Glaucoma and/or Ocular Hypertension Patients Treated With Xalacom® After Failure of Previous Antiglaucoma Therapy.
This study is designed to evaluate the safety and tolerability of Xalacom in patients with primary glaucoma
- Trial name
- NCT00801437
- Testing
- Xalacom
- Where
- 39 sites in Slovakia
- Volunteers
- 457 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Glaucoma
Surgical Retinotomy for the Treatment of Glaucoma
Glaucoma is a leading cause of blindness worldwide. It is caused by persistently elevated intraocular pressure causing progressive visual field loss.
- Trial name
- NCT03798145
- Testing
- Surgical Retinotomy
- Sponsor
- Stanford University
Patient Satisfaction, Waiting Times, Patient Pathways, Effect of Lifestyle-related, Clinical and Demographic Parameters on Outcomes
Reducing Waiting Time for Vision Refraction Services
The Out-Patient Departments (OPD) is often the first point of contact for patients seeking healthcare services and involves the coordination of both administrative and clinical processes.
- Trial name
- NCT07416175
- Testing
- VRR service optimization
- Volunteers
- 350 people
- Sponsor
- Seva Canada Society
Wet Age-related Macular Degeneration, Neovascular Age-related Macular Degeneration
ADVM-022 Intravitreal Gene Therapy for Wet AMD
ADVM-022 (AAV.7m8-aflibercept) is a gene therapy product developed for the treatment of neovascular (wet) age-related macular degeneration (wet AMD).
- Trial name
- OPTIC (NCT03748784)
- Testing
- ADVM-022
- Where
- 11 sites in United States
- Volunteers
- 30 people
- Sponsor
- Adverum Biotechnologies, Inc.
Experience, Life, Dialysis
What Does the Patient Experience Represent for Patients and Caregivers in Dialysis?
The primary objective of this work is to describe the vision, representations, and beliefs of professionals and patients regarding the role and place of the user during their care journey at the Calydial renal health facility.
- Conditions
- Experience, Life, Dialysis, Patient Engagement, Patient Participation
- Trial name
- EnquêteXP (NCT06529887)
- Where
- 4 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Calydial
Allergic Conjunctivitis (AC)
A Multi-Center Environmental Study for the Treatment of Moderate to Severe Ocular Allergic Conjunctivitis
This is a Phase III multi-center, double-masked, vehicle-controlled, randomized, parallel group study evaluating the efficacy, safety and tolerability of EBI-005 as compared to vehicle given as a topical ophthalmic solution in…
- Trial name
- EBI-005-AC-2 (NCT02492321)
- Testing
- EBI-005
- Where
- 11 sites in United States
- Volunteers
- 250 people
- Sponsor
- Eleven Biotherapeutics