Clinical trials: Visual Acuity
Visual Acuity
2-week Evaluation of Marketed Silicone Hydrogel Contact Lenses in Indian Population
The primary objective of this study is to evaluate the clinical performance of two marketed silicone hydrogel contact lenses in an Indian population in the following areas: physiological characteristics, comfort characteristics…
- Trial name
- NCT02394808
- Testing
- senofilcon A, lotrafilcon B
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Marketed Contact Lens Real World Through Focus Curve
This is a single-visit prospective study to establish a real world Marketed Contact Lens 'Through Focus Curve' (TFC) measurement by comparing the consistency of vision between myopes and hyperopes.
- Trial name
- NCT02679976
- Testing
- etafilcon A
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Study to Evaluate the Visual Performance of Three Multifocal IOLs
The purpose of this study is to compare the performances of 2 bifocal IOLs and 1 trifocal IOL for far, near and intermediate vision.
- Trial name
- NCT02990689
- Testing
- Trifocal Intraocular Lens, Bifocal Intraocular Lens, Low Addition Bifocal Intraocular Lens
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Diabetes Mellitus, Macular Edema
Intravitreal Aflibercept Injection in Vision Impairment Due to DME
To determine the efficacy of intravitreally (IVT) administered VEGF Trap-Eye on the best-corrected visual acuity (BCVA) assessed by the early treatment diabetic retinopathy study (ETDRS) chart in subjects with diabetic macular…
- Trial name
- VIVID-DME (NCT01331681)
- Testing
- VEGF Trap-Eye (BAY86-5321), Macular Laser Photocoagulation (Control)
- Where
- 73 sites in Australia, Austria and 9 more
- Volunteers
- 406 people
- Sponsor
- Bayer
Non-Infectious Anterior Uveitis
Oftac Eye Drops (0.05% Tacrolimus Ophthalmic Emulsion) for the Treatment of Active Non-infectious Anterior Uveitis
The goal of this clinical trial is to assess the safety and tolerability of Oftac in active non-infectious anterior uveitis patients. The main questions it aims to answer are: 1.
- Trial name
- NCT07869953
- Testing
- Oftac: 0.05% tacrolimus ophthalmic emulsion
- Where
- 7 sites in Israel
- Volunteers
- 18 people
- Sponsor
- BioNanoSim Ltd.
Visual Acuity, Meibomian Gland
Clinical Evaluation of Therapeutic Meibomian Gland Expression
This will be a single centre pilot study to evaluate appearance of the Meibomian glands.
- Trial name
- NCT04997135
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of a Lipid- Based Lubricating Eye Drop
This is a single visit, randomized, double masked, bilateral, non-dispensing, 2×2 crossover study to assess visual acuity.
- Trial name
- NCT06131476
- Testing
- Blink® Tears eye drops, Investigational lipid eye drops
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Comparison of ACUVUE® OASYS MAX 1-Day Multifocal and DAILIES® AquaComfort Plus® Multifocal
This study is a 4-visit, multi-site, prospective, controlled, randomized, single-masked (subjects), two-arm parallel group, bilateral, dispensing clinical trial to compare the performance of the Test lens to the Control lens in…
- Trial name
- NCT07788521
- Testing
- Senofilcon A, Nelfilcon A
- Where
- 11 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Approved and Investigational Contact Lenses Using New UV Additive
Randomized, 8-visit dispensing study over 14 weeks to evaluate the safety and efficacy of an investigational contact lens with a new UV blocker compared to a marketed contact lens.
- Trial name
- NCT02982018
- Testing
- senofilcon A with new UV blocker, senofilcon A
- Where
- 6 sites in United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of ACUVUE OASYS® 1-Day for Astigmatism Lenses Produced on a New Manufacturing Line
This is a bilateral, dispensing, randomized, controlled, double-masked, 2×2 cross-over study to evaluate the clinical performance of ACUVUE OASYS® 1-Day for Astigmatism contact lenses produced on a recently qualified…
- Trial name
- NCT04794270
- Testing
- ACUVUE OASYS® 1-Day for Astigmatism - TAM 24, ACUVUE OASYS® 1-Day for Astigmatism
- Where
- 5 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Relapsing Remitting Multiple Sclerosis, Optic Neuropathy
Nanocrystalline Gold to Treat Remyelination Failure in Chronic Optic Neuropathy In Multiple Sclerosis
The objective of this trial is to assess the efficacy and safety of CNM-Au8 as a remyelinating treatment for vision-impairing MS lesions in participants who have chronic vision impairment as a result of Relapsing-Remitting…
- Conditions
- Relapsing Remitting Multiple Sclerosis, Optic Neuropathy, Optic; Neuritis, With Demyelination
- Trial name
- VISIONARY-MS (NCT03536559)
- Testing
- CNM-Au8
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 73 people
- Sponsor
- Clene Nanomedicine
Visual Acuity
Clinical Performance of Two Daily Disposable Silicone Hydrogel Contact Lenses
This is a subject-masked, randomized, bilateral, 2x2 crossover clinical investigation that will assess lens fit acceptance.
- Trial name
- NCT05554640
- Testing
- Acuvue® Oasys MAX 1-Day, Dailies Total 1
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Aphakia, Cataract
Comparison of Aspheric Toric & Non-toric Aphakic Intraocular Lenses
The purpose of this multi-center clinical trial is to determine the safety and efficacy of the HSO Toric IOLs for the correction of aphakia and reduction of pre-existing refractive astigmatism.
- Trial name
- COAST (NCT01268540)
- Testing
- FY-60AD, NHT15, NHT30, & NHT53
- Where
- 6 sites in United States
- Volunteers
- 235 people
- Sponsor
- Hoya Surgical Optics, Inc.
Retinal Dystrophies, Color Vision Defects
Natural History Study of Inherited Retinal Diseases
This prospective, observational investigation seeks to delineate the interplay between chromatic vision deficits and both functional visual outcomes and anatomical retinal biomarkers in individuals affected by Inherited Retinal…
- Conditions
- Retinal Dystrophies, Color Vision Defects, Vision Disorders, Macular Degeneration
- Trial name
- MojiLVCDT (NCT07085533)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhongmou Therapeutics
Visual Acuity
Evaluation of a Toric Multifocal Contact Lens Manufactured in Etafilcon Material in a Low ADD Hyperopic Population
The study is a bilateral, single-masked, single-arm, 3-visit dispensing study. There will be one study treatment, with the subject being in the treatment for approximately 12-16 days.
- Trial name
- NCT03713281
- Testing
- Toric Multifocal etafilcon A with PVP
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Biomarker Discovery in Two Daily Disposable Contact Lenses
This is a non-masked, non-randomized, stratified, 4-arm parallel group, non-interventional study where subjects will be enrolled into one of four arms based on their habitual contact lenses.
- Trial name
- NCT03440242
- Testing
- JJVC Contact Lens, Marketed Contact Lens
- Where
- 2 sites in India
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Visual Acuity With a Reusable Toric Multifocal Contact Lens
The study is a bilateral, single-masked, single-arm, 4-visit dispensing study evaluating the visual performance of the study lenses.
- Trial name
- NCT05000164
- Testing
- Bausch + Lomb Ultra® Multifocal for Astigmatism
- Where
- 9 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of 2-Week Reusable ACUVUE 2 Vivid Style
This will be a single site, non-randomized, dispensing, brand-masked to the subject, bilateral single treatment study. There will be 2 study visits with a 10 to 14-day contact lens wear period between visits.
- Trial name
- NCT03431441
- Testing
- JJVC Marketed Contact Lens
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Investigational Multifocal Contact Lenses
3-visit dispensing study to evaluate the subjective feedback of a multifocal contact lens in a population of presbyopic patients. Subjects will wear the contact lenses for a total of 12-16 days.
- Trial name
- NCT03059810
- Testing
- etafilcon A
- Where
- 9 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses
This study is a 2-phase adaptive approach utilizing a 2×2 crossover design. The study lenses will be worn in a bilateral fashion for a period of approximately 1-week each.
- Trial name
- NCT04968925
- Testing
- ACUVUE Oasys 1-Day, Precision 1
- Where
- 10 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.