Clinical trials: Visual Performance
Cataract Extraction, Corneal Astigmatism
Assessment of Visual Performance in Patients With Low Levels of Astigmatism
To assess visual performance in patients with low levels (0.5-0.75 Diopters) of corneal astigmatism.
- Trial name
- NCT00842231
- Testing
- Visual performance measures
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Presbyopia
Multifocal Visual Performance Study
The purpose of this trial was to compare the functional visual performance of Precision Profile Multifocal (MF) contact lenses to Progressive Addition Lens (PAL) spectacles in a presbyopic population.
- Trial name
- NCT03757039
- Testing
- Multifocal soft contact lenses, Progressive addition lens spectacles
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 42 people
- Sponsor
- Alcon Research
Visual Performance
Evaluation of Two Marketed Multifocal Contact Lenses
This is a single-masked, randomized, cross-over, dispensing, 6- visit pilot study. The purpose of this clinical study is to evaluate the performance of two marketed multifocal lenses.
- Trial name
- NCT03322423
- Testing
- Multifocal Contact Lens 1, Multifocal Contact Lens 2, Spherical Contact Lens 2
- Where
- 5 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Performance
Visual Performance of Senofilcon A With and Without a New UV/HEV-filter
This study will occur in two non-dispensing phases: Phase 1 is a non-randomized, non-masked, non-dispensing study where subjects will wear their own contact lenses for approximately 1 hour.
- Trial name
- NCT05021081
- Testing
- TRP-200, ACUVUE Oasys 1-Day
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Multifocal High ADD Contact Lens Proof of Concept Trial
The purpose of this study is to evaluate the visual performance of a new multifocal High ADD contact lens compared to the currently-marketed AIR OPTIX® AQUA MULTIFOCAL (AOAMF) High ADD Contact Lens.
- Trial name
- NCT02117544
- Testing
- Lotrafilcon B multifocal contact lenses (new), Lotrafilcon B multifocal contact lenses
- Volunteers
- 268 people
- Sponsor
- Alcon Research
Visual Performance
Investigation of Ocular Signs & Symptoms in Wearers Fitted With Contact Lenses Following Digital Device Use
The objective of this study is to assess how various silicone hydrogel lenses perform when worn by subjects who are heavy digital device users.
- Trial name
- NCT02394756
- Testing
- Marketed Soft Contact lens, AIR OPTIX® AQUA, Biofinity®
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Performance of Two Daily Disposable Silicone Hydrogel Contact Lenses
This is a subject-masked, randomized, bilateral, 2x2 crossover clinical investigation that will assess lens fit acceptance.
- Trial name
- NCT05554640
- Testing
- Acuvue® Oasys MAX 1-Day, Dailies Total 1
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Visual Performance of Soft Contact Lenses With Myopia Control Optics
This is a multi-site, bilateral, dispensing, randomized, controlled, single-masked, 3x3 crossover study with a run-in period.
- Trial name
- NCT05141448
- Testing
- 1-Day Acuvue Moist, EMO-118, EMO-114
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Visual Assessment of DAILIES® AquaComfort Plus® for Astigmatism as Compared to 1-DAY ACUVUE® MOIST® for Astigmatism
The purpose of this study is to evaluate functional vision associated with rotational stability at blink of DAILIES® AquaComfort Plus® Toric (DACP T) compared to 1-DAY ACUVUE® MOIST® for Astigmatism (1DAM A).
- Trial name
- NCT02071771
- Testing
- Nelfilcon A toric contact lenses, Etafilcon A toric contact lenses
- Volunteers
- 80 people
- Sponsor
- Alcon Research
Cataract
Effect of Blue Light Filtration on Visual Performance
The purpose of this study is to evaluate photostress recovery with blue light filter clip-on glasses among pseudophakes [ie, subjects in which the natural lens of the eye has been replaced with an artificial lens (intraocular…
- Trial name
- NCT01938989
- Testing
- Clear clip-on glasses, Blue light filter clip-on glasses
- Volunteers
- 158 people
- Sponsor
- Alcon Research
Dry Eye Syndromes
Evaluation of Maintaining Visual Performance in Participants Who Engage in Electronic Visual Tasking While Using Restasis®
This study will evaluate the efficacy of Restasis® in participants with dry eye disease who engage in electronic visual tasking.
- Trial name
- EMPOWER (NCT02554981)
- Testing
- Cyclosporine 0.05% Ophthalmic Emulsion
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Allergan
Dry Eye Syndromes
Investigation of Maintaining Visual Performance Achieved With Cyclosporine Therapy
This study will evaluate the safety and efficacy of cyclosporine 0.05% ophthalmic emulsion (Restasis®) in patients with dry eye disease.
- Trial name
- IMPACT (NCT02121847)
- Testing
- cyclosporine 0.05% ophthalmic emulsion, carboxymethylcellulose-based lubricant eye drops
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Allergan
Visual Acuity
Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses
This will be an open-label, 3-visit, single-arm, dispensing clinical trial to evaluate visual acuity.
- Trial name
- NCT06377488
- Testing
- JJVC Investigational Multifocal Toric Contact Lens manufactured in Senofilcon A (C3) material with UV blocker / HEV filter
- Where
- 15 sites in United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors, Myopia
Performance Assessment of a Modified Daily Disposable Contact Lens
The purpose of this study is to compare visual acuity between two daily disposable contact lenses.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT03762668
- Testing
- Modified delefilcon A contact lenses, Delefilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Dry Eye
The Effect of Systane Ultra Lubricant Eye Drops (FID 112903) on Visual Performance
To evaluate the effect of 2 different lubricant eye drops on visual function of patients with dry eye
- Trial name
- NCT00673764
- Testing
- Systane Ultra Lubricant Eye Drops, Optive Lubricant Eye Drops
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Alcon Research
Astigmatism
Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)
The purpose of this study is to generate clinical data to quantify the impact of residual astigmatism on the overall visual performance during distance, intermediate, and near viewing in patients implanted with Clareon Vivity…
- Trial name
- NCT06784063
- Testing
- Clareon Vivity Extended Vision IOL
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Refractive Error, Astigmatism
Visual Performance Investigation of Two Toric Soft Contact Lenses
The purpose of this study is to compare the amount of coma as measured by aberrometry induced by two silicone hydrogel toric lenses in astigmatic participants.
- Conditions
- Refractive Error, Astigmatism, Myopia, Hyperopia
- Trial name
- CARDINAL (NCT01858701)
- Testing
- Lotrafilcon B toric contact lens, Comfilcon A toric contact lens
- Volunteers
- 49 people
- Sponsor
- Alcon Research
Visual Acuity
Evaluation of On-eye Optical Performances of the RMY-100 Lens
This is a two-arm parallel, non-masked, bilateral, non-dispensing study with one Test arm and one concurrent, non-randomized Control arm to evaluate the one-eye optical performances of the test soft contact lens and compare with…
- Trial name
- NCT03670277
- Testing
- etafilcon A, Habitual Orthokeratology Lenses
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Performance of Senofilcon A Investigational Lens
This study is a controlled, randomized, subject-masked, 2-arm parallel, 2-week dispensing, bilateral evaluation where the study lenses are worn for a minimum of 5 days per week and 6 hours per day.
- Trial name
- NCT05300763
- Testing
- senofilcon A prototype, Dailies Total 1
- Where
- 19 sites in United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia, Refractive Error
DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance
The purpose of this study is to evaluate the visual performance of DAILIES® Aqua Comfort Plus® (DACP) MF contact lens using new objective measurements.
- Trial name
- NCT02235831
- Testing
- Nelfilcon A MF contact lenses (DACP MF), Nelfilcon A single vision contact lenses (DACP)
- Volunteers
- 24 people
- Sponsor
- Alcon Research