Clinical trials: Visualization
Homonymous Hemianopsia, Homonymous Quadrantanopia
PAVE (Parallactic Visual-Field Enhancement) System for Treatment of Chronic Visual Field Loss Due to Stroke, Traumatic Brain Injury, or Brain Surgery
This is a research study to evaluate the effectiveness of the PAVE (Parallactic Visual-Field Enhancement) System for the treatment of chronic visual field loss due to stroke, traumatic brain injury, or brain surgery.
- Trial name
- NCT07185971
- Testing
- PAVE (Parallactic Visual-Field Enhancement) treatment using a virtual reality head mounted display
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- NeuroAEye LLC
Diabetic Macular Edema
Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema
The purpose of this study was to evaluate the efficacy and safety of brolucizumab in treatment of patients with visual impairment due to diabetic macular edema (DME).
- Trial name
- KESTREL (NCT03481634)
- Testing
- Brolucizumab, Aflibercept
- Where
- 116 sites in United States, Argentina and 12 more
- Volunteers
- 566 people
- Sponsor
- Novartis Pharmaceuticals
Postoperative Visual Outcomes Following Cataract Surgery in Patients With Prior Myopic Corneal Laser Vision Correction
Evaluation of Cataract Surgery Outcomes in Patients With Prior Laser Vision Correction Implanted With the CT LUCIA Lens
This is a prospective, Phase IV, post-approval observational study evaluating postoperative outcomes in patients with a history of myopic corneal laser vision correction (LVC) undergoing bilateral cataract surgery with…
- Trial name
- NCT07084545
- Testing
- CT LUCIA 621P Intraocular Lens Implantation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Carl Zeiss Meditec AG
Depressive Disorder, Major Depressive Disorder
Study of Virtual Reality-based Medical Device for Patients with Depressive Disorder
This study apply a wearable visual device (HMD)-VR-based software medical device for patients with depressive disorder for 8 weeks.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Depressive Episode
- Trial name
- NCT05701345
- Testing
- OMNIFIT DTx-MDD, standard treatment
- Where
- 5 sites in South Korea
- Volunteers
- 162 people
- Sponsor
- Omni C&S
Asthenopia
Objective and Subjective Evaluation of Ophthalmic Lenses With Extra Power
To evaluate subjective visual performance and objective visual parameters when wearing ophthalmic lenses with extra power (+0.4 D or +0.6 D), and ophthalmic lenses with a selective blue cut filter.
- Trial name
- NCT05089240
- Testing
- Ophthalmic lens with extra power
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Essilor International
Visual Display Users With Previously Undiagnosed Dry Eye
Study of External Neuromodulation to Improve Signs and Symptoms of Dry Eye in Visual Display Terminal Users
Two study arms - sham and treatment; There will be a cross over of the sham group to the treatment group at day 15.
- Trial name
- NCT04763018
- Testing
- iTEAR100
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Olympic Ophthalmics, Inc.
Leber Hereditary Optic Disease
Efficacy and Safety Study of Bilateral IVT Injection of GS010 at Two Dose Levels in LHON Patients
The goal of this Clinical trial is to assess the safety and efficacy of GS010 at two dose levels on visual acuity and retinal mitochondrial activity in patients affected with ND4 Leber Hereditary Optic Neuropathy (LHON)
- Trial name
- REVISE (NCT07303296)
- Testing
- GS010 High dose, GS010 Low dose
- Where
- France
- Volunteers
- 14 people
- Sponsor
- GenSight Biologics
Neovascular Age-related Macular Degeneration (nAMD)
A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)
Study WR42221 is a Phase IIIb, global, multicenter, randomized, visual assessor-masked study designed to assess the efficacy, safety, and pharmacokinetics of the Port Delivery System with ranibizumab (PDS) 100 mg/mL delivered…
- Trial name
- NCT04657289
- Testing
- Ranibizumab, Port Delivery System with Ranibizumab
- Where
- 104 sites in Argentina, Australia and 14 more
- Volunteers
- 451 people
- Sponsor
- Hoffmann-La Roche
Glioma, Malignant, Computer-Assisted
Radiomics-Based Visualization and Quantitative Validation of IDH1 Heterogeneity in Gliomas
The goal of this clinical trail is to non-invasively visualise and quantitatively validate an radiomics model of genetic heterogeneity in adult patients with diffuse glioma to help clinicians better guide surgical resection and…
- Trial name
- NCT05969691
- Testing
- Validation of IDH1 mutations from the radiomics model
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Mingge LLC
Visual Acuity
Clinical and Laboratory Study of Lysozyme Deposition on Daily Disposable Contact Lenses
In vitro studies show that some hydrogel materials uptake more lysozyme than other hydrogel materials and that this protein remains largely active and promotes reduced cytokine response in an in vitro culture of human corneal…
- Trial name
- NCT02365298
- Testing
- etafilcon A, nelfilcon A
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population
This is a single-masked, randomized-controlled, dispensing clinical trial. A total of approximately 60 eligible myopic subjects will be targeted to complete the study.
- Trial name
- NCT03581825
- Testing
- senofilcon A Multifocal, senofilcon A Sphere, etafilcon A Multifocal
- Where
- 6 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Evaluation of Orientation and Visual Acuity of Four Toric Soft Contact Lenses When Head is Tilted at 90 Degrees
The purpose of this study is to determine the relative performance of a new toric soft contact lens against three toric contact lens currently available in market, specifically with orientation and visual acuity when head is…
- Trial name
- NCT00583908
- Testing
- senofilcon A, balafilcon A toric, lotrafilcon B toric
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Intervertebral Disc Degeneration
Safety and Performance of the SPINEVISION Hexanium ACIF in the Treatment of Cervical Spine Degenerative Disc Disease
The goal of this observational study is to confirm the safety and efficacy of the Hexanium ACIF system in the treatment of skeletally mature patients suffering from degenerative disc disease (disease that occurs when the spinal…
- Trial name
- NCT06155409
- Testing
- Anterior cervical interbody fusion
- Where
- 6 sites in France
- Volunteers
- 148 people
- Sponsor
- SPINEVISION SAS
Peri-orbital Wrinkles, Peri-oral Wrinkles
Peri-orbital and Peri-oral Wrinkle Reduction Trial
This is prospective, multi-center, single-blinded, non-randomized clinical trial. Enrolled subjects will receive two Ulthera® treatments on the peri-orbital and peri-oral regions, each treatment provided 30 days apart.
- Trial name
- NCT01981252
- Testing
- Ulthera® System Treatment
- Where
- 5 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Visual Acuity
The Effects of Contact Lenses With UV/HEV-Filter on Visual Function
This is a 2-phase, single-site, non-dispensing, randomized, controlled, double-masked, 2x2 crossover study to objectively measure potential benefits of a new UV/HEV filter using psychophysical testing techniques.
- Trial name
- NCT05601544
- Testing
- ACUVUE OASYS 1-Day, ACUVUE OASYS MAX 1-Day, ACUVUE OASYS Multifocal
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population Phase 2
This is a single-masked, randomized-controlled, dispensing clinical trial. A total of approximately 60 eligible hyperopic subjects will be targeted to complete this study.
- Trial name
- NCT03586648
- Testing
- senofilcon A Multifocal, senofilcon A Sphere, etafilcon A Multifocal
- Where
- 6 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Dynamic Characterisation of Meibomian Gland Structure
This will be a single center pilot study to evaluate appearance of the Meibomian glands.
- Trial name
- NCT04649606
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Two Cosmetic Contact Lenses
This is a single visit, single-masked, non-dispensing, randomized, controlled, 2×2 bilateral crossover study to evaluate visual acuity.
- Trial name
- NCT06864858
- Testing
- etafilcon A with PVP with cosmetic pattern contact lens, 1-DAY ACUVUE® DEFINE® with LACREON®, FRESH Honey
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Diabetic Macular Edema
A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)
This Phase 3 study will evaluate the efficacy, durability, and safety of KSI-301 compared to aflibercept in participants with treatment-naïve DME.
- Trial name
- GLEAM (NCT04611152)
- Testing
- KSI-301, Aflibercept
- Where
- 75 sites in United States, Germany and 6 more
- Volunteers
- 460 people
- Sponsor
- Kodiak Sciences Inc
Subjects Undergoing Cataract Surgery and Insertion of IOL
Clinical Evaluation of TrueVision System: LRI and Capsulorhexis Templates
To evaluate the ability of the TRUEVISION 3D VISUALIZATION AND GUIDANCE SYSTEM FOR MICROSURGERY to provide the ophthalmic surgeon appropriate alignment, orientation and sizing information during cataract or refractive lens…
- Trial name
- NCT01123343
- Testing
- TrueVision 3D Visualization and Guidance System for MicroSurgery
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- TrueVision Systems, Inc