Clinical trials: Vitamin A Deficiency
Vitamin D Deficiency, Pregnancy
Vitamin D Status of Pregnant Women and Their Children in Eau Claire, South Carolina
Science News (October 2004) called vitamin D deficiency a "silent epidemic" in America, with no group unaffected. Using new guidelines of optimal vitamin D levels, more than 90% of African American women now suffer from vitamin D…
- Trial name
- NCT00412087
- Testing
- cholecalciferol (vitamin D3), cholecalciferol
- Where
- United States
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Chronic Kidney Disease, Vitamin D Deficiency
Vitamin D and Coronary Calcification Study
Patients with chronic kidney disease (CKD) have a higher mortality rate than the general population, with cardiovascular disease (CVD) accounting for approximately 50% of deaths.
- Conditions
- Chronic Kidney Disease, Vitamin D Deficiency, Coronary Calcification, Disorders of Calcium and Bone Metabolism
- Trial name
- VCOR (NCT00752102)
- Testing
- Calcitriol (Rocaltrol®), Paricalcitol
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Joslin Diabetes Center
X-linked Hypophosphatemia
X-linked Hypophosphatemia and FGF21
Fibroblast Growth Factor 23 and Fibroblast Growth Factor 21 are two endocrine Fibroblast Growth Factors, requiring Klotho as a co-factor to promote their systemic actions.
- Trial name
- XLH 21 (NCT03596554)
- Testing
- Descriptive study
- Where
- 3 sites in France
- Volunteers
- 39 people
- Sponsor
- Hospices Civils de Lyon
Vitamin D Deficiency, Thoracic Surgery
Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level
Our research group has shown that almost all children with congenital heart disease (CHD) are vitamin D deficient following heart surgery.
- Conditions
- Vitamin D Deficiency, Thoracic Surgery, Pediatric Disorders, Heart Defects, Congenital
- Trial name
- HICCUPS 2 (NCT01838447)
- Testing
- Cholecalciferol
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Children's Hospital of Eastern Ontario
Vitamin D Deficiency
Muscle Metabolic Function in Older Adults With Different Vitamin D Status Before and After Exercise
This is a small pilot aerobic training trial designed to examine differences between normal-high and low vitamin D levels and 7-days of aerobic training on local VO2 measured by non-invasive Hybrid Diffuse Optical Spectroscopy.
- Trial name
- NCT02485197
- Testing
- 7 continuous days of aerobic training
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- David Travis Thomas
Cytokine Storm
The Effect of D3 on Selected Cytokines Involved in Cytokine Storm in the Covid-19 Uninfected Jordanian People
The effect of Weekly 50,000 IU vitamin D3 supplements on the serum levels of selected cytokines involved in cytokine storm of Covid-19; A randomized clinical trial in the Covid-19 uninfected people with vitamin D deficiency.
- Trial name
- NCT04476745
- Testing
- Vitamin D3
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Arterial Hypertension, Vitamin D Deficiency
Styrian Vitamin D Hypertension Trial
In this randomized, double-blind, placebo-controlled trial we plan to enrol 200 vitamin D deficient hypertensive patients. Our main objective is to evaluate whether vitamin D3 supplementation with 2,800 IU daily for 8 weeks has…
- Trial name
- NCT02136771
- Testing
- Vitamin D3
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Graz
Vitamin D Deficiency
Controlled Trial of Prenatal Vitamin D3 Supplementation to Prevent Vitamin D Deficiency in Mothers and Their Infants
The purpose of this research study is to compare the effects of higher dose vitamin D with commonly recommended dose in pregnant women to see which is better in achieving and/or maintaining sufficient vitamin D blood levels…
- Trial name
- PA 03-103 (NCT00610688)
- Testing
- Prenatal Vitamin, Cholecalciferol (Vitamin D3)
- Where
- 2 sites in United States, United Arab Emirates
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
X-Linked Hypophosphatemia
Efficacy and Safety of Burosumab Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With XLH
The primary objective of this study is to evaluate the effect of KRN23 (burosumab) therapy in improving rickets in children with XLH compared with active control (oral phosphate/active vitamin D).
- Trial name
- NCT02915705
- Testing
- burosumab, Oral Phosphate Supplement, active vitamin D
- Where
- 16 sites in United States, Australia and 5 more
- Volunteers
- 61 people
- Sponsor
- Kyowa Kirin, Inc.
Vitamin A Deficiency in Children
Prevalence Of Vitamin A Deficiency In Critically Ill Children With Sepsis And Its Association With Clinical Outcomes
Aim of the work is to assess the prevalence of vitamin A deficiency in critically ill children with sepsis and the association between vitamin A deficiency and clinical outcomes
- Trial name
- NCT06391437
- Testing
- Extraction of blood sample
- Where
- Egypt
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Benha University
Polycystic Ovary Syndrome, Vitamin D Deficiency
The Effects of Vitamin D on Angiogenic Factors in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) affects 5 to 10% of women of reproductive age. It is characterized by a cluster of hyperandrogenism, hyperinsulinemia, menstrual dysfunction, hirsutism and infertility.
- Trial name
- NCT02460380
- Testing
- Vitamin D3
- Volunteers
- 93 people
- Sponsor
- Maimonides Medical Center
Undernutrition
Nutributter Programming to Prevent Undernutrition: an Evaluation
This randomized, controlled effectiveness study examines Nutributter programming within an integrated package of maternal and child health services offered by Haiti's Ministry of Health (MSPP) to prevent undernutrition among…
- Trial name
- NPPU (NCT01552512)
- Testing
- Nutributter Program, Integrated Package
- Where
- Haiti
- Volunteers
- 1,228 people
- Sponsor
- Washington University School of Medicine
Sepsis
Adrenal Cortical Function and Vitamin A Deficiency in Sepsis
The study involves the participant to receive a 250 mcg Cortrosyn (ACTH) Stimulation Test to test the ability of the body to make Cortisol.
- Trial name
- NCT03152474
- Testing
- Solumedrol 20mg, Vitamin A 100,000 IU
- Volunteers
- 300 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Diabetes Mellitus Type 2, Hypovitaminosis D
Diabetes Intervention Trial With Vitamin D in Subjects of Nordic and Sub-Indian Ethnicity
The aim of this 6 months study is to evaluate the metabolic effects of 400.000-600.000 IU of vitamin D supplementation in subjects with type 2 diabetes and hypovitaminosis D.
- Trial name
- DIVINE (NCT00992797)
- Testing
- Cholecalciferol, Orange juice
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital, Aker
Thiamine Deficiency
Further Development and Assessment of Tools to Measure Risk Factors for and Treatment of Thiamine Deficiency Disorders
Thiamine deficiency, including the most severe form infantile beriberi, is a public health concern across South and Southeast Asia, where monotonous diets rely on thiamine-poor white rice.
- Trial name
- NCT05390086
- Testing
- Standard of care
- Where
- 2 sites in Laos
- Volunteers
- 42 people
- Sponsor
- University of California, Davis
X-linked Hypophosphatemia
Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)
The primary efficacy objective of this study is to establish the effect of burosumab treatment compared with placebo on increasing serum phosphorus levels in adults with XLH.
- Trial name
- NCT02526160
- Testing
- burosumab
- Where
- 25 sites in United States, France and 5 more
- Volunteers
- 134 people
- Sponsor
- Kyowa Kirin, Inc.
Methicillin Resistant Staphylococcus Aureus, Vitamin D3 Deficiency
Efficacy Study of Vitamin D Supplementation to Meticillin Resistant Staphylococcus Aureus (MRSA) Carriers
The purpose of this study is to treat persistent MRSA carriers with vitamin D supplementation during a 12 month to see if the number of MRSA positive patients can be reduced.
- Trial name
- D-STAPH (NCT02178488)
- Testing
- Cholecalciferol
- Where
- 2 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Peter Bergman