Clinical trials: Vitamin A Deficiency, active
Retinal Disease, Age-Related Macular Degeneration
Stem Cell Ophthalmology Treatment Study II
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.
- Conditions
- Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease
- Trial name
- SCOTS2 (NCT03011541)
- Testing
- Arm 1
- Where
- 4 sites in United States, Austria and 1 more
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Kidney Diseases, Dialysis; Complications
PRevEnting FracturEs in REnal Disease - 1
PREFERRED-1 is a pilot study designed to determine the feasibility of a large randomized, pragmatic, open-label, comparative-effectiveness trial of denosumab for the prevention of fragility fractures in people receiving…
- Conditions
- Kidney Diseases, Dialysis; Complications, Fragility Fracture, Chronic Kidney Disease-Mineral and Bone Disorder
- Trial name
- PREFERRED-1 (NCT05096195)
- Testing
- Denosumab 60 mg/ml, Calcium and vitamin D prophylaxis, Monitoring of post-injection calcium and phosphate
- Where
- 6 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Western University, Canada
Irritable Bowel Syndrome (IBS), Vitamin D Deficiency
Role of Vitamin D Supplementation in Children With Irritable Bowel Syndrome
This study was designed to determine whether vitamin D supplementation improved symptoms in children with irritable bowel syndrome, a condition associated with repeated abdominal pain and changes in bowel habits.
- Trial name
- NCT07914478
- Testing
- Vitamin D3
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Aziz Bhatti Shaheed Teaching Hospital
Critical Illness, Vitamin D Deficiency
The VITDALIZE Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients
In the VITdAL-ICU trial using a large oral dose of vitamin D3 in 480 adult critically ill patients, there was no benefit regarding the primary endpoint hospital length of stay.
- Conditions
- Critical Illness, Vitamin D Deficiency, Covid19
- Trial name
- VITDALIZE (NCT03188796)
- Testing
- Cholecalciferol
- Where
- 18 sites in Austria, Belgium and 2 more
- Volunteers
- 2,400 people
- Sponsor
- Medical University of Graz
X-linked Hypophosphatemia
A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia
A first-in-human study of KK8123 in adults with X-linked hypophosphatemia.
- Trial name
- NCT06525636
- Testing
- KK8123
- Where
- 10 sites in United States, Canada and 3 more
- Volunteers
- 39 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Vitamin D Deficiency
Vitamin D Status and Its Influencing Factors in Zhejiang Province: A Multicenter Cross-Sectional Study
Vitamin D deficiency is a global public health problem, with an estimated 1 billion people affected worldwide, and large-scale systematic data for Zhejiang Province remain scarce.
- Trial name
- NCT07866391
- Where
- 2 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Acute Respiratory Infections, Critical Illness in Children
Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections
Acute respiratory infections (ARIs) are among the leading causes of hospitalization, morbidity, and mortality in children worldwide, particularly among critically ill patients admitted to pediatric intensive care units (PICUs).
- Conditions
- Acute Respiratory Infections, Critical Illness in Children, Vitamin D Deficiency, Pediatric Respiratory Infections
- Trial name
- VITD-ARI (NCT06547749)
- Testing
- Serum 25-Hydroxyvitamin D Assessment
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Assiut University
X-linked Hypophosphatemia (XLH)
Effective Dosing of Burosumab in XLH
X-linked hypophosphataemia (XLH) is a rare, hereditary condition. The genetic defect leads to low blood phosphate levels and vitamin D suppression. Phosphate is required for strong bones and teeth and to store energy in cells.
- Trial name
- NCT07183579
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Vitamin A Deficiency, Idiopathic Scoliosis
Effect of Vitamin A Supplementation on Idiopathic Scoliosis
This study aims to investigate whether vitamin A supplementation can influence spinal curve magnitude in idiopathic scoliosis children and potentially prevent its de novo development.
- Trial name
- NCT07335991
- Testing
- Vitamin A, Nutritional Education
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Chronic Kidney Diseases, Hypertension
Integrated Diagnosis and Treatment of CKD on Outcomes
Objective: To establish a study cohort and follow up of patients with CKD in our hospital, and evaluate the status of integrated CKD diagnosis and treatment according to guidelines in the real world, as well as the clinical…
- Conditions
- Chronic Kidney Diseases, Hypertension, Hyperglycemia, Hyperlipidemias
- Trial name
- NCT05242055
- Testing
- Integrated diagnosis and treatment for CKD
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Capital Medical University
Visual Snow Syndrome, Migraine
Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli
The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: Does VSS arise from spontaneous activity in brain pathways?…
- Conditions
- Visual Snow Syndrome, Migraine, Healthy
- Trial name
- VPVSS (NCT06961864)
- Testing
- Visual Adaptation, Assessments and Questionnaires, Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pulpitis - Irreversible, Vitamin D Deficiency
Effect of Vitamin D on Postoperative Pain in Symptomatic Irreversible Pulpitis
Vitamin D deficiency (VDD) is a prevalent global health concern that has been linked to altered pain perception through its effects on inflammatory pathways, nociceptor activity, and neurotrophic signaling.
- Trial name
- NCT07579637
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Future University in Egypt
Non-allergic Asthma, Obesity
Effects of Vitamin D Supplementation in Adolescents With Asthma, Obesity and Vitamin D Deficiency.
Obesity has been associated with a specific non-allergic asthma phenotype and to a deficiency of vitamin D in at least 90% of the pediatric population.
- Conditions
- Non-allergic Asthma, Obesity, Vitamin D Deficiency
- Trial name
- NCT05431920
- Testing
- Vitamin D₃ (25-hydroxy vitamin D)
- Where
- Mexico
- Volunteers
- 264 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Diabetes Mellitus, Erectile Dysfunction
Is There a Benefit From Addition of Exercise in Diabetic Patients With ED Who Complain Low Vitamin D?
males with diabetes complain impotence in the presence of low vitamin D deficiency. pharacmological treatment of low vitamin D levels is necessary but changing lifestyle by performing exercise is also important
- Conditions
- Diabetes Mellitus, Erectile Dysfunction, Vitamin D Deficiency
- Trial name
- NCT07366970
- Testing
- exercise and vitamin D intake, vitamin D intake
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hypovitaminosis D
Cholecalciferol and Calcifediol Are Both Useful to Improve Vitamin D Serum Levels
Patients with hypovitaminosis D are randomized into three arms of treatment: Group A: Calcifediol 0,266mg each month Group B: Cholecalciferol 25000UI each 15 days Group C: Calcifediol 4 drops per day.
- Trial name
- VITD (NCT06138249)
- Testing
- Vitamin D
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Infant Vitamin K Status, Vitamin K Deficiency Bleeding
The OK Daily Study
The OK Daily Study is a multi-centred, part-randomised, part blinded, four cohort study. We are exploring daily dietary supplementation with vitamin K2, specifically menaquinone-7 (MK-7), given to breastfed infants or…
- Trial name
- NCT07620236
- Testing
- Combined MK-7 + vitamin D3 drops, Vitamin D3 Drops, MK-7 capsules
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Otosclerosis of Middle Ear, Bone Density
Investigating the Relationship Between Temporal Bone CT, Bone Density, and Hearing Loss in Otosclerosis Patients
The goal of this observational case-control study is to evaluate the relationship between temporal bone computed tomography (CT) findings, bone mineral density (BMD), and audiological parameters in adults diagnosed with…
- Conditions
- Otosclerosis of Middle Ear, Bone Density, Vitamin D Deficiency
- Trial name
- NCT06830187
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- İbrahim Emir Yeşil
Obesity, Bariatric Surgery
Effectiveness of a Modified Cost-Effective Dietary Plan in Promoting Weight Loss and Preservation of Lean Body Mass in Patients After Bariatric Surgery
This study will see if a low-cost dietary plan, based on the standard dietary guidelines of the American Society for Metabolic and Bariatric Surgery (ASMBS) and using locally available foods, can help patients lose weight and…
- Conditions
- Obesity, Bariatric Surgery, Nutritional Status, Body Composition
- Trial name
- NCT07111767
- Testing
- Low-Cost Post-Bariatric Diet, Standard High-cost Post-Bariatric Diet
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Khyber Teaching Hospital
Hypovitaminosis b 12
This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcting Early-onset Vitamin B12 Deficiency in Adult Patients Using Proton Pump Inhibitors (PPIs). The Primary Outcome is the Change in Serum Vitamin B12 Levels Over a 6-week
This randomized, clinical trial evaluates the efficacy of oral versus sublingual vitamin B12 supplementation in correcting early-onset vitamin B12 deficiency in adult patients using proton pump inhibitors (PPIs).
- Trial name
- NCT06966856
- Testing
- Cyanocobalamin 1000 Mcg Oral Tablet, Cyanocobalamin 1000 Mcg Sublingual Tablet, Proton Pump Inhibitor therapy only
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Tanta University
Vitamin A, Vitamin A Deficiency
Vitamin A Status in Patients With Vocal Fold Leukoplakia
This study will determine systemic vitamin A status and lesion histopathology of participants with vocal fold hyperkeratosis resulting in clinical leukoplakia.
- Conditions
- Vitamin A, Vitamin A Deficiency, Leukoplakia, Vocal Cord Neoplasm
- Trial name
- NCT05323292
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison