Clinical trials: Vitamin D, open to volunteers
X-linked Hypophosphatemia
A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia
A first-in-human study of KK8123 in adults with X-linked hypophosphatemia.
- Trial name
- NCT06525636
- Testing
- KK8123
- Where
- 10 sites in United States, Canada and 3 more
- Volunteers
- 39 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Obesity & Overweight, Vitamin D
Exercise Training and Vitamin D Metabolism
The prevalence of Vitamin D deficiency is significantly higher in adults with overweight/obesity compared to those with normal body mass index (BMI).
- Trial name
- Hybri-D (NCT07300332)
- Testing
- Exercise training, Control
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Diabetic Neuropathy
Vitamin D, Nerve Growth Factor and Nerve Conduction Studies in Adult Male Type 2 Diabetic Neuropathy Patients
study the relationship of vitamin d with nerve growth factor level and nerve conduction studies in adult male type 2 diabetic neuropathy patients
- Trial name
- NCT07236723
- Testing
- nerve conduction studies, Nerve Growth Factor, 25(OH) vitamin D
- Where
- 2 sites in Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Aswan University
Vitamin D Deficiency
Vitamin D Status and Its Influencing Factors in Zhejiang Province: A Multicenter Cross-Sectional Study
Vitamin D deficiency is a global public health problem, with an estimated 1 billion people affected worldwide, and large-scale systematic data for Zhejiang Province remain scarce.
- Trial name
- NCT07866391
- Where
- 2 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Healthy Adult, Cognitive Measures
Multivitamin Intervention and Cognitive Function
The purpose of this trial is to learn how a multivitamin combined blueberry polyphenol supplement (Vitals+) influences cognitive function in healthy adults.
- Trial name
- NCT06795789
- Testing
- Vitals+ (combined multivitamin and polyphenol supplement)
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Braincare Limited
Alopecia Areata
Comparison of Topical Calcipotriol and Intralesional Steroids in Alopecia Areata
This randomized controlled trial compares the effectiveness of topical calcipotriol and intralesional corticosteroids in the treatment of alopecia areata.
- Trial name
- CALISTA-AA (NCT07453238)
- Testing
- Calcipotriol, Triamcinolone Acetonide
- Volunteers
- 60 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Acute Respiratory Infections, Critical Illness in Children
Serum Vitamin D Status in Critically Ill Children With Acute Respiratory Infections
Acute respiratory infections (ARIs) are among the leading causes of hospitalization, morbidity, and mortality in children worldwide, particularly among critically ill patients admitted to pediatric intensive care units (PICUs).
- Conditions
- Acute Respiratory Infections, Critical Illness in Children, Vitamin D Deficiency, Pediatric Respiratory Infections
- Trial name
- VITD-ARI (NCT06547749)
- Testing
- Serum 25-Hydroxyvitamin D Assessment
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Assiut University
Epilepsy
Effects of Mega-dose Vitamin D Pulse and Maintenance Therapy on Seizure Frequency, Fatigue, and Quality of Life: A Prospective Study
This prospective study aims to evaluate the effects of mega-dose vitamin D pulse therapy followed by maintenance therapy on seizure frequency, fatigue, and quality of life in patients with epilepsy.
- Trial name
- NCT06736002
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chin-Wei Huang
Vitamin D, Dietary Supplement
Non-inferiority RCT on Fish Waste-Derived vs. Synthetic Vitamin D Supplementation in Healthy Adults With Suboptimal Vitamin D Levels
Vitamin D is a fat-soluble vitamin with hormone-like properties, essential for numerous physiological processes in humans. It plays a central role in maintaining calcium and phosphorus homeostasis, promoting intestinal absorption…
- Trial name
- NCT07127796
- Testing
- Dietary Supplement - Fish-derived Vitamin D, Dietary Supplement - Synthetic Vitamin D
- Volunteers
- 48 people
- Sponsor
- University of Bologna
X-linked Hypophosphatemia (XLH)
Effective Dosing of Burosumab in XLH
X-linked hypophosphataemia (XLH) is a rare, hereditary condition. The genetic defect leads to low blood phosphate levels and vitamin D suppression. Phosphate is required for strong bones and teeth and to store energy in cells.
- Trial name
- NCT07183579
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Selective Eating, Emotional Dysregulation
Unflavored Powdered Multivitamin in Children
The goal of this clinical trial is to learn whether a daily unflavored powdered multivitamin (EllaOla Kids Essentials) improves mood and behavior in children aged 4 to 11 who are picky eaters and experience behavioral challenges.
- Conditions
- Selective Eating, Emotional Dysregulation, Child Behavior, Healthy Children (Wellness Study)
- Trial name
- BLOSSOM (NCT07863050)
- Testing
- EllaOla Kids Essentials Unflavored Powdered Multivitamin
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- EllaOla
Maxillary Canine Retraction, Local Calcitriol Delivery
Clinical Evaluation of Local Calcitriol Delivery on Maxillary Canine Retraction
This study will evaluate the effect of locally applied Calcitriol on dental and skeletal changes during upper canine retraction.
- Conditions
- Maxillary Canine Retraction, Local Calcitriol Delivery, Orthodontic Tooth Movement
- Trial name
- CALCR25 (NCT07200349)
- Testing
- Calcitriol Delivery
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Type 2 Diabetes
Relationship Between Insulin Resistance and Vitamin D in Type 2 Diabetes Mellitus (DM)
The primary aim of the study is to evaluate the association between vitamin D levels and triglyceride-glucose index as a marker of insulin resistance in patients with type 2 DM.
- Trial name
- DM (NCT07467161)
- Volunteers
- 165 people
- Sponsor
- Assiut University
Old Age; Atrophy
The Effect of a Combined Personalized Nutritional Intervention and a Personalized Graded Activity Functional Training Program on Physical Performance in Hospitalized Older Patients, Compared to Usual Care
This project aims to improve physical performance in older patients, by offering a personalized combined nutritional intervention with a physical activity training program.
- Trial name
- FITFOOD (NCT05413616)
- Testing
- FITFOOD lifestyle intervention
- Where
- Netherlands
- Volunteers
- 136 people
- Sponsor
- Radboud University Medical Center
Renal Osteodystrophy, Chronic Kidney Diseases
Precision Medicine Approaches to Renal Osteodystrophy
Treatment of renal osteodystrophy is impeded by the lack of practical and accurate tools to determine underlying bone turnover. Gold standard bone biopsy is not practical in the clinic for the vast majority of kidney disease…
- Conditions
- Renal Osteodystrophy, Chronic Kidney Diseases, CKD-MBD, Bone Turnover Rate Disorder
- Trial name
- PMaROD (NCT05880914)
- Testing
- miRNAseq analysis, Standard treatment for bone disorder
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Thomas Nickolas
Acute Coronary Syndromes
Impact of Atorvastatin Versus Rosuvastatin on 25 Hydroxy Vitamin D Levels in Patients With Acute Coronary Syndrome
there will be 2 groups of patients with acute coronary syndrome. The patients will receive one of the 2 study drugs and impact on raising Vitamin D level will be seen after 6 months
- Trial name
- NCT06765265
- Testing
- Rosuvastatin 20 mg/day, Atorvastatin 40 mg
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- King Edward Medical University
T Cell Response to Dried Plum, Vitamin D Influence on Immune Response
Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women
Prior studies have shown that dietary supplementation with dried plums (also known as prunes) reduces bone loss in postmenopausal women.
- Conditions
- T Cell Response to Dried Plum, Vitamin D Influence on Immune Response, Dried Plum and Immune Function
- Trial name
- NCT07222111
- Testing
- Dried plums
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Healthy Volunteer
Supplementation Absorption Comparison
The goal of this interventional study is to compare the absorption of supplements with and without absorption enhancing technology in healthy volunteers.
- Trial name
- PHAABS (NCT07791797)
- Testing
- Aquacelle® Omega 3, Comparator Omega 3, Plexosome® Vitamin D3
- Where
- Australia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Vitamin D Insufficiency
Investigating the Impact of Vitamin D Biofortified Tomatoes on Serum Levels of 25(OH)D
In the UK, vitamin D deficiency occurs frequently especially during the winter months. Vitamin D biofortified tomatoes have been developed using precision breeding technique by researchers at John Innes Centre.
- Trial name
- ViTaL-D (NCT07142759)
- Testing
- Precision Bred Provitamin D-rich Tomato Soup, Precision Bred Vitamin D-rich Tomato Soup, Wild-type (store-bought) Tomato Soup
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- Quadram Institute Bioscience
Hemodialysis, Chronic Pain
Effects of Multiple Mega-dose of Vitamin D3 Supplementation on Ameliorating Moderate to Severe Chronic Pain in Hemodialysis Patients
Pain is a major complaint in hemodialysis (HD) patients. Concentrations of parathyroid hormone (PTH) >250 pg/ml are associated with chronic pain.
- Conditions
- Hemodialysis, Chronic Pain, Hyperparathyroidism
- Trial name
- NCT05667090
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University Hospital