Clinical trials: Vitamin D Deficiency/Insufficiency
Chronic Kidney Disease, Renal Osteodystrophy
Serum Sclerostin Levels, Cardiovascular Parameters and Carpal Tunnel Syndrome in Maintenance Hemodialysis Patients
Sclerostin, the product of the SOST gene, located on chromosome 17, locus q11.2 in humans, was originally believed to be a non-classical Bone morphogenetic protein (BMP) antagonist.Sclerostin was recently identified as a…
- Conditions
- Chronic Kidney Disease, Renal Osteodystrophy, Left Ventricular Hypertrophy
- Trial name
- NCT01382966
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- RFM Renal Treatment Services
Chronic Kidney Disease, Vitamin D Deficiency
hCAP18 Levels and Vitamin D Deficiency in Chronic Kidney Disease
The human immune system produces a protein called hCAP18 (also known as LL-37 or cathelicidin). This protein is believed to help the body to fight infections.
- Trial name
- NCT01026363
- Testing
- Ergocalciferol, Calcitriol
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Impaired Fasting Glucose, Impaired Glucose Tolerance
D Vitamin Intervention in VA
This study will supplement African American male (AAM) veterans at risk for diabetes and newly diagnosed T2DM with vitamin D (low or higher dose) and evaluate whether vitamin D helps to improve early markers of diabetes.
- Conditions
- Impaired Fasting Glucose, Impaired Glucose Tolerance, Vitamin D Insufficiency
- Trial name
- DIVA (NCT01375660)
- Testing
- 50K vitamin D2
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- US Department of Veterans Affairs
Kidney Transplantation, Anemia
Correcting Anemia and Native Vitamin D Supplementation in Kidney Transplant Recipients
The purpose of this study is to evaluate the effect of anemia correction and vitamin D supplementation in kidney transplant recipients.
- Conditions
- Kidney Transplantation, Anemia, Vitamin D Deficiency, Renal Insufficiency, Chronic
- Trial name
- CANDLE-KIT (NCT01817699)
- Testing
- High Hb target, cholecalciferol
- Where
- Japan
- Volunteers
- 161 people
- Sponsor
- CANDLE-KIT Trial Study Group
Depression, Postpartum Depression
Is Vitamin D Insufficiency and Deficiency Associated With Antepartum and Postpartum Depression?
Our primary aim is to evaluate whether Vitamin D deficiency causes depressive symptoms in antepartum and postpartum depression and whether early correction of Vitamin D deficiency improves these symptoms.
- Trial name
- NCT02272387
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Kidney Failure, Chronic, Anemia
Cholecalciferol Supplementation for Anemia and Mineral and Bone Disorder in Hemodialysis Patients
The purpose of this study is to determine whether cholecalciferol supplementation decrease the blood concentrations of hepcidin-25 in hemodialysis patients.
- Conditions
- Kidney Failure, Chronic, Anemia, Vitamin D Deficiency, Bone Diseases, Metabolic
- Trial name
- CHAMBER (NCT02214563)
- Testing
- Cholecalciferol, Olive oil
- Where
- 7 sites in Japan
- Volunteers
- 90 people
- Sponsor
- Takayuki Hamano
Endometriosis, Vitamin D Deficiency/Insufficiency
Analysis of Vitamin D and VDR Expression in Endometriosis: A Case-Control Study
The goal of this cross-sectional prospective matching study is to evaluate whether serum vitamin D levels and vitamin D receptor (VDR) expression are associated with the presence and severity of endometriosis in women of…
- Conditions
- Endometriosis, Vitamin D Deficiency/Insufficiency, Vitamin D Status
- Trial name
- NCT06289257
- Testing
- Vitamin D level, Vitamin D receptor
- Where
- Thailand
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Chronic Kidney Disease
Different Effects of Non-calcium Phosphate Binders on Serum Calcium
Sevelamer hydrochloride (SE) can increase intestinal calcium absorption in contrast to lanthanum carbonate (LA). Study compared effect of LA and SE on serum and urine phosphate and calcium, and hormones regulating mineral-bone…
- Trial name
- NCT03451019
- Testing
- Sevelamer Hydrochloride, Lanthanum Carbonate
- Where
- Poland
- Volunteers
- 34 people
- Sponsor
- Medical University of Lodz
Chronic Kidney Disease Mineral and Bone Disorder
Phosphorus Absorption in Healthy Adults and in Patients With Moderate Chronic Kidney Disease
Chronic kidney disease (CKD) affects approximately 26 million Americans with many more at risk for disease development. Elevated serum phosphorus (P) and related abnormalities in P homeostasis due to progressive loss of kidney…
- Trial name
- NCT03108222
- Testing
- Phosphorus Absorption Test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Vitamin D Deficiency, Hypocalcemia
Effect of Vitamin D Supplement on Disease Activity in SLE
To study the effect of vitamin D supplementation on disease activity of SLE ( SLEDAI-2K ) and IL-6 level
- Conditions
- Vitamin D Deficiency, Hypocalcemia, Hyperparathyroidism, Systemic Lupus Erythematosus (Disorder)
- Trial name
- NCT05260255
- Testing
- vitamin D2 ( calciferol )
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Kidney Failure, Chronic, Chronic Kidney Disease-Mineral and Bone Disorder
DePTH: De-emphasize PTH
The De-emphasize Parathyroid Hormone (DePTH) Study is a 12-month pragmatic, randomized, parallel-group, active comparator, open-label, blinded end-point study of 90 patients with incident or prevalent secondary…
- Trial name
- NCT06288451
- Testing
- Oral calcitriol with cinacalcet rescue, IV activated vitamin D
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Washington
Vitamin D Deficiency, Vitamin D Insufficiency
Solius UV Light Source in Improving Serum Levels of 25-hydroxyvitamin D
This is a feasibility interventional study seeking to determine the safety and efficacy of the Solius Photobiologic System in increasing the serum levels of 25(OH)D in a vitamin D deficient/insufficient adult population.
- Trial name
- NCT04865432
- Testing
- UVB treatment
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston University
Coronary Artery Disease, Chronic Kidney Disease
Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease
The purpose of this study is to determine if vitamin D supplementation changes the results of certain tests associated with inflammation in the body using an oral, synthetic form of vitamin D called paricalcitol.
- Conditions
- Coronary Artery Disease, Chronic Kidney Disease, Hypovitaminosis D, Secondary Hyperparathyroidism
- Trial name
- VINCA-CKD (NCT01012414)
- Testing
- paricalcitol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Thomas Jefferson University
Chronic Kidney Disease, End Stage Renal Disease
Klotho Gene Polymorphism in Dialyzed Patients With Hyperphosphatemia
Patients with chronic kidney disease (CKD) and those with end-stage renal disease (ESRD) undergoing renal replacement therapies show elevated serum phosphate levels which predispose them to cardiovascular calcifications and high…
- Conditions
- Chronic Kidney Disease, End Stage Renal Disease, Hyperphosphatemia, Renal Osteodystrophy
- Trial name
- NCT00374712
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hydroxylase Deficiency
Influence of Kidney Performance and Magnesium on Formation of (OH)2-vitamin D3
Retrospective database analysis. The target values are the serum values of 25(OH)D, of 1,25(OH)2D, of magnesium and creatinine as well as age and sex of the patients. The laboratory values of the years 2017 and 2018 are included.
- Trial name
- NCT04237480
- Testing
- serum value 1,25(OH)2 vitamin D
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Kidney Disease Stage 5
Efficacy of Plant-protein Diets in Patients With Chronic Kidney Disease
The purpose of this study is to evaluate the efficacy of plant-protein diets for 12 weeks in patients with advanced chronic kidney disease.
- Trial name
- NCT05350098
- Testing
- Plant-protein Diets, Control Diets
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Osaka University
Chronic Kidney Disease Mineral and Bone Disorder, Chronic Kidney Disease (CKD)
The CPH-MBD Cohort
Persons with chronic kidney disease (CKD) have a 3-fold increased risk of bone fracture and a 10-fold increased risk of cardiovascular disease than the general population.
- Conditions
- Chronic Kidney Disease Mineral and Bone Disorder, Chronic Kidney Disease (CKD), Bone Markers
- Trial name
- NCT07193056
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Herlev Hospital
Chronic Kidney Diseases
SOP's for CKD-MBD-Biomarkers
CKD-MBD (Chronic Kidney Disease - Mineral and Bone Disorder) is an extensive disease and includes dysfunction of the mineral metabolism, the bone metabolism and cardiovascular diseases in the context of renal insufficiency.
- Trial name
- NCT02708368
- Testing
- blood withdrawal
- Where
- 2 sites in Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Osteoporosis, Chronic Kidney Disease Mineral and Bone Disorder
Osteoporosis & Renal Disease: Research in Primary Health Care Services
Osteoporosis, a silent and multifactorial systemic skeletal disorder, severely compromises bone strength and significantly increases the risk of fragility fractures.
- Trial name
- NCT07848490
- Testing
- Fracture risk assessment tool (FRAX), Dual-Energy X-ray Absorptiometry (DXA)
- Where
- Portugal
- Volunteers
- 622 people
- Sponsor
- Universidade do Porto
Vitamin D Deficiency, Vitamin D Insufficiency
Trial to Assess Vitamin D Requirements in Lactating Women
This is a randomized, placebo-controlled trial of vitamin D supplementation with 20mcg cholecalciferol (to achieve a total intake of 25mcg/day), with or without 500mg calcium to assess vitamin D requirements in lactating women…
- Trial name
- DMUMs (NCT01349127)
- Testing
- 20µg Vitamin D3, 20µg Vitamin D3 + 500 mg Calcium
- Where
- Ireland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University College Cork